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Published by Robert Bruce at August 29th, 2023 , Revised On September 5, 2023

Biology Research Topics

Are you in need of captivating and achievable research topics within the field of biology? Your quest for the best biology topics ends right here as this article furnishes you with 100 distinctive and original concepts for biology research, laying the groundwork for your research endeavor.

Table of Contents

Our proficient researchers have thoughtfully curated these biology research themes, considering the substantial body of literature accessible and the prevailing gaps in research.

Should none of these topics elicit enthusiasm, our specialists are equally capable of proposing tailor-made research ideas in biology, finely tuned to cater to your requirements. 

Thus, without further delay, we present our compilation of biology research topics crafted to accommodate students and researchers.

Research Topics in Marine Biology

• Impact of climate change on coral reef ecosystems.
• Biodiversity and adaptation of deep-sea organisms.
• Effects of pollution on marine life and ecosystems.
• Role of marine protected areas in conserving biodiversity.
• Microplastics in marine environments: sources, impacts, and mitigation.

Biological Anthropology Research Topics

• Evolutionary implications of early human migration patterns.
• Genetic and environmental factors influencing human height variation.
• Cultural evolution and its impact on human societies.
• Paleoanthropological insights into human dietary adaptations.
• Genetic diversity and population history of indigenous communities.

Biological Psychology Research Topics 

• Neurobiological basis of addiction and its treatment.
• Impact of stress on brain structure and function.
• Genetic and environmental influences on mental health disorders.
• Neural mechanisms underlying emotions and emotional regulation.
• Role of the gut-brain axis in psychological well-being.

Cancer Biology Research Topics 

• Targeted therapies in precision cancer medicine.
• Tumor microenvironment and its influence on cancer progression.
• Epigenetic modifications in cancer development and therapy.
• Immune checkpoint inhibitors and their role in cancer immunotherapy.
• Early detection and diagnosis strategies for various types of cancer.

Also read: Cancer research topics

Cell Biology Research Topics

• Mechanisms of autophagy and its implications in health and disease.
• Intracellular transport and organelle dynamics in cell function.
• Role of cell signaling pathways in cellular response to external stimuli.
• Cell cycle regulation and its relevance to cancer development.
• Cellular mechanisms of apoptosis and programmed cell death.

Developmental Biology Research Topics 

• Genetic and molecular basis of limb development in vertebrates.
• Evolution of embryonic development and its impact on morphological diversity.
• Stem cell therapy and regenerative medicine approaches.
• Mechanisms of organogenesis and tissue regeneration in animals.
• Role of non-coding RNAs in developmental processes.

Also read: Education research topics

Human Biology Research Topics

• Genetic factors influencing susceptibility to infectious diseases.
• Human microbiome and its impact on health and disease.
• Genetic basis of rare and common human diseases.
• Genetic and environmental factors contributing to aging.
• Impact of lifestyle and diet on human health and longevity.

Molecular Biology Research Topics 

• CRISPR-Cas gene editing technology and its applications.
• Non-coding RNAs as regulators of gene expression.
• Role of epigenetics in gene regulation and disease.
• Mechanisms of DNA repair and genome stability.
• Molecular basis of cellular metabolism and energy production.

Research Topics in Biology for Undergraduates

• 41. Investigating the effects of pollutants on local plant species.
• Microbial diversity and ecosystem functioning in a specific habitat.
• Understanding the genetics of antibiotic resistance in bacteria.
• Impact of urbanization on bird populations and biodiversity.
• Investigating the role of pheromones in insect communication.

Synthetic Biology Research Topics 

• Design and construction of synthetic biological circuits.
• Synthetic biology applications in biofuel production.
• Ethical considerations in synthetic biology research and applications.
• Synthetic biology approaches to engineering novel enzymes.
• Creating synthetic organisms with modified functions and capabilities.

Animal Biology Research Topics 

• Evolution of mating behaviors in animal species.
• Genetic basis of color variation in butterfly wings.
• Impact of habitat fragmentation on amphibian populations.
• Behavior and communication in social insect colonies.
• Adaptations of marine mammals to aquatic environments.

Also read: Nursing research topics

Best Biology Research Topics 

• Unraveling the mysteries of circadian rhythms in organisms.
• Investigating the ecological significance of cryptic coloration.
• Evolution of venomous animals and their prey.
• The role of endosymbiosis in the evolution of eukaryotic cells.
• Exploring the potential of extremophiles in biotechnology.

Biological Psychology Research Paper Topics

• Neurobiological mechanisms underlying memory formation.
• Impact of sleep disorders on cognitive function and mental health.
• Biological basis of personality traits and behavior.
• Neural correlates of emotions and emotional disorders.
• Role of neuroplasticity in brain recovery after injury.

Biological Science Research Topics: 

• Role of gut microbiota in immune system development.
• Molecular mechanisms of gene regulation during development.
• Impact of climate change on insect population dynamics.
• Genetic basis of neurodegenerative diseases like Alzheimer’s.
• Evolutionary relationships among vertebrate species based on DNA analysis.

Biology Education Research Topics 

• Effectiveness of inquiry-based learning in biology classrooms.
• Assessing the impact of virtual labs on student understanding of biology concepts.
• Gender disparities in science education and strategies for closing the gap.
• Role of outdoor education in enhancing students’ ecological awareness.
• Integrating technology in biology education: challenges and opportunities.

Biology-Related Research Topics

• The intersection of ecology and economics in conservation planning.
• Molecular basis of antibiotic resistance in pathogenic bacteria.
• Implications of genetic modification of crops for food security.
• Evolutionary perspectives on cooperation and altruism in animal behavior.
• Environmental impacts of genetically modified organisms (GMOs).

Biology Research Proposal Topics

• Investigating the role of microRNAs in cancer progression.
• Exploring the effects of pollution on aquatic biodiversity.
• Developing a gene therapy approach for a genetic disorder.
• Assessing the potential of natural compounds as anti-inflammatory agents.
• Studying the molecular basis of cellular senescence and aging.

Biology Research Topic Ideas

• Role of pheromones in insect mate selection and behavior.
• Investigating the molecular basis of neurodevelopmental disorders.
• Impact of climate change on plant-pollinator interactions.
• Genetic diversity and conservation of endangered species.
• Evolutionary patterns in mimicry and camouflage in organisms.

Biology Research Topics for Undergraduates 

• Effects of different fertilizers on plant growth and soil health.
• Investigating the biodiversity of a local freshwater ecosystem.
• Evolutionary origins of a specific animal adaptation.
• Genetic diversity and disease susceptibility in human populations.
• Role of specific genes in regulating the immune response.

Cell and Molecular Biology Research Topics 

• Molecular mechanisms of DNA replication and repair.
• Role of microRNAs in post-transcriptional gene regulation.
• Investigating the cell cycle and its control mechanisms.
• Molecular basis of mitochondrial diseases and therapies.
• Cellular responses to oxidative stress and their implications in ageing.

These topics cover a broad range of subjects within biology, offering plenty of options for research projects. Remember that you can further refine these topics based on your specific interests and research goals.

Frequently Asked Questions 

What are some good research topics in biology?

A good research topic in biology will address a specific problem in any of the several areas of biology, such as marine biology, molecular biology, cellular biology, animal biology, or cancer biology.

A topic that enables you to investigate a problem in any area of biology will help you make a meaningful contribution. 

How to choose a research topic in biology?

Choosing a research topic in biology is simple. 

Follow the steps:

• Generate potential topics. 
• Consider your areas of knowledge and personal passions. 
• Conduct a thorough review of existing literature.
•  Evaluate the practicality and viability. 
• Narrow down and refine your research query. 
• Remain receptive to new ideas and suggestions.

Who Are We?

For several years, Research Prospect has been offering students around the globe complimentary research topic suggestions. We aim to assist students in choosing a research topic that is both suitable and feasible for their project, leading to the attainment of their desired grades. Explore how our services, including research proposal writing , dissertation outline creation, and comprehensive thesis writing , can contribute to your college’s success.

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Dorsal root ganglion-derived exosomes deteriorate neuropathic pain by activating microglia via the microRNA-16-5p/HECTD1/HSP90 axis

The activated microglia have been reported as pillar factors in neuropathic pain (NP) pathology, but the molecules driving pain-inducible microglial activation require further exploration. In this study, we in...

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MicroRNA-721 regulates gluconeogenesis via KDM2A-mediated epigenetic modulation in diet-induced insulin resistance in C57BL/6J mice

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Rapid development and mass production of SARS-CoV-2 neutralizing chicken egg yolk antibodies with protective efficacy in hamsters

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Obesity, associated with the intake of a high-fat diet (HFD), and anxiety are common among those living in modern urban societies. Recent studies suggest a role of microbiome-gut-brain axis signaling, includin...

General regulatory factors exert differential effects on nucleosome sliding activity of the ISW1a complex

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Establishment of primary prostate epithelial and tumorigenic cell lines using a non-viral immortalization approach

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The effect of diabetes mellitus on differentiation of mesenchymal stem cells into insulin-producing cells

Diabetes mellitus (DM) is a global epidemic with increasing incidences. DM is a metabolic disease associated with chronic hyperglycemia. Aside from conventional treatments, there is no clinically approved cure...

Control of astrocytic Ca 2+ signaling by nitric oxide-dependent S-nitrosylation of Ca 2+ homeostasis modulator 1 channels

Astrocytes Ca 2+ signaling play a central role in the modulation of neuronal function. Activation of metabotropic glutamate receptors (mGluR) by glutamate released during an increase in synaptic activity triggers ...

Increased levels and activation of the IL-17 receptor in microglia contribute to enhanced neuroinflammation in cerebellum of hyperammonemic rats

Patients with liver cirrhosis may show minimal hepatic encephalopathy (MHE) with mild cognitive impairment and motor incoordination. Rats with chronic hyperammonemia reproduce these alterations. Motor incoordi...

Identification and expression analysis of two steamer-like retrotransposons in the Chilean blue mussel ( Mytilus chilensis )

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Noncoding RNAs in skeletal development and disorders

Protein-encoding genes only constitute less than 2% of total human genomic sequences, and 98% of genetic information was previously referred to as “junk DNA”. Meanwhile, non-coding RNAs (ncRNAs) consist of app...

Cx43 hemichannels and panx1 channels contribute to ethanol-induced astrocyte dysfunction and damage

Alcohol, a widely abused drug, significantly diminishes life quality, causing chronic diseases and psychiatric issues, with severe health, societal, and economic repercussions. Previously, we demonstrated that...

Galectins in epithelial-mesenchymal transition: roles and mechanisms contributing to tissue repair, fibrosis and cancer metastasis

Galectins are soluble glycan-binding proteins that interact with a wide range of glycoproteins and glycolipids and modulate a broad spectrum of physiological and pathological processes. The expression and subc...

Glutaminolysis regulates endometrial fibrosis in intrauterine adhesion via modulating mitochondrial function

Endometrial fibrosis, a significant characteristic of intrauterine adhesion (IUA), is caused by the excessive differentiation and activation of endometrial stromal cells (ESCs). Glutaminolysis is the metabolic...

The long-chain flavodoxin FldX1 improves the biodegradation of 4-hydroxyphenylacetate and 3-hydroxyphenylacetate and counteracts the oxidative stress associated to aromatic catabolism in Paraburkholderia xenovorans

Bacterial aromatic degradation may cause oxidative stress. The long-chain flavodoxin FldX1 of Paraburkholderia xenovorans LB400 counteracts reactive oxygen species (ROS). The aim of this study was to evaluate the...

MicroRNA-148b secreted by bovine oviductal extracellular vesicles enhance embryo quality through BPM/TGF-beta pathway

Extracellular vesicles (EVs) and their cargoes, including MicroRNAs (miRNAs) play a crucial role in cell-to-cell communication. We previously demonstrated the upregulation of bta-mir-148b in EVs from oviductal...

YME1L-mediated mitophagy protects renal tubular cells against cellular senescence under diabetic conditions

The senescence of renal tubular epithelial cells (RTECs) is crucial in the progression of diabetic kidney disease (DKD). Accumulating evidence suggests a close association between insufficient mitophagy and RT...

Effects of latroeggtoxin-VI on dopamine and α-synuclein in PC12 cells and the implications for Parkinson’s disease

Parkinson’s disease (PD) is characterized by death of dopaminergic neurons leading to dopamine deficiency, excessive α-synuclein facilitating Lewy body formation, etc. Latroeggtoxin-VI (LETX-VI), a proteinaceo...

Glial-restricted progenitor cells: a cure for diseased brain?

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Carbapenem-resistant hypervirulent ST23 Klebsiella pneumoniae with a highly transmissible dual-carbapenemase plasmid in Chile

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Endometrial mesenchymal stromal/stem cells improve regeneration of injured endometrium in mice

The monthly regeneration of human endometrial tissue is maintained by the presence of human endometrial mesenchymal stromal/stem cells (eMSC), a cell population co-expressing the perivascular markers CD140b an...

Embryo development is impaired by sperm mitochondrial-derived ROS

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Fibroblasts inhibit osteogenesis by regulating nuclear-cytoplasmic shuttling of YAP in mesenchymal stem cells and secreting DKK1

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MSC-derived exosomes protect auditory hair cells from neomycin-induced damage via autophagy regulation

Sensorineural hearing loss (SNHL) poses a major threat to both physical and mental health; however, there is still a lack of effective drugs to treat the disease. Recently, novel biological therapies, such as ...

Alpha-synuclein dynamics bridge Type-I Interferon response and SARS-CoV-2 replication in peripheral cells

Increasing evidence suggests a double-faceted role of alpha-synuclein (α-syn) following infection by a variety of viruses, including SARS-CoV-2. Although α-syn accumulation is known to contribute to cell toxic...

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Growing evidence has suggested that Type I Interferon (I-IFN) plays a potential role in the pathogenesis of Down Syndrome (DS). This work investigates the underlying function of MX1, an effector gene of I-IFN,...

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Abnormal remodeling of the pulmonary vasculature, characterized by the proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) along with dysregulated glycolysis, is a pathognomonic feat...

Electroacupuncture promotes neurogenesis in the dentate gyrus and improves pattern separation in an early Alzheimer's disease mouse model

Impaired pattern separation occurs in the early stage of Alzheimer’s disease (AD), and hippocampal dentate gyrus (DG) neurogenesis participates in pattern separation. Here, we investigated whether spatial memo...

Role of SYVN1 in the control of airway remodeling in asthma protection by promoting SIRT2 ubiquitination and degradation

Asthma is a heterogenous disease that characterized by airway remodeling. SYVN1 (Synoviolin 1) acts as an E3 ligase to mediate the suppression of endoplasmic reticulum (ER) stress through ubiquitination and de...

Advances towards the use of gastrointestinal tumor patient-derived organoids as a therapeutic decision-making tool

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Atherosclerosis (AS), a significant contributor to cardiovascular disease (CVD), is steadily rising with the aging of the global population. Pyroptosis and apoptosis, both caspase-mediated cell death mechanism...

Prenatal ethanol exposure and changes in fetal neuroendocrine metabolic programming

Prenatal ethanol exposure (PEE) (mainly through maternal alcohol consumption) has become widespread. However, studies suggest that it can cause intrauterine growth retardation (IUGR) and multi-organ developmen...

Autologous non-invasively derived stem cells mitochondria transfer shows therapeutic advantages in human embryo quality rescue

The decline in the quantity and quality of mitochondria are closely associated with infertility, particularly in advanced maternal age. Transferring autologous mitochondria into the oocytes of infertile female...

Development of synthetic modulator enabling long-term propagation and neurogenesis of human embryonic stem cell-derived neural progenitor cells

Neural progenitor cells (NPCs) are essential for in vitro drug screening and cell-based therapies for brain-related disorders, necessitating well-defined and reproducible culture systems. Current strategies em...

Heat-responsive microRNAs participate in regulating the pollen fertility stability of CMS-D2 restorer line under high-temperature stress

Anther development and pollen fertility of cytoplasmic male sterility (CMS) conditioned by Gossypium harknessii cytoplasm (CMS-D2) restorer lines are susceptible to continuous high-temperature (HT) stress in sum...

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The effect of zofenopril on the cardiovascular system of spontaneously hypertensive rats treated with the ACE2 inhibitor MLN-4760

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Two murine models of sepsis: immunopathological differences between the sexes—possible role of TGFβ1 in female resistance to endotoxemia

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An intracellular, non-oxidative factor activates in vitro chromatin fragmentation in pig sperm

In vitro incubation of epididymal and vas deferens sperm with Mn 2+ induces Sperm Chromatin Fragmentation (SCF), a mechanism that causes double-stranded breaks in toroid-linker regions (TLRs). Whether this mechani...

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S -Nitrosylation in endothelial cells contributes to tumor cell adhesion and extravasation during breast cancer metastasis

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Identifying pyroptosis- and inflammation-related genes in intracranial aneurysms based on bioinformatics analysis

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Mucin1 induced trophoblast dysfunction in gestational diabetes mellitus via Wnt/β-catenin pathway

To elucidate the role of Mucin1 (MUC1) in the trophoblast function (glucose uptake and apoptosis) of gestational diabetes mellitus (GDM) women through the Wnt/β-catenin pathway.

Human umbilical cord mesenchymal stem cells (hUC-MSCs) alleviate paclitaxel-induced spermatogenesis defects and maintain male fertility

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Exploring the Neandertal legacy of pancreatic ductal adenocarcinoma risk in Eurasians

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• ISSN: 0717-6287 (electronic)

Biological Research

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General Biology

(11 reviews)

Paul Doerder, Cleveland State University

Ralph Gibson, Cleveland State University

Copyright Year: 2015

Publisher: WikiBooks

Language: English

Formats Available

Conditions of use.

Learn more about reviews.

Reviewed by Tricia Paramore, Biology instructor and Department Chair, Hutchinson Community College on 3/2/22

While the book does touch upon many areas, the text reads more like a student notes packet and it fails to address the ecology side of biology. Ecology makes up one unit of my course, so this book would not work. The following is written on... read more

Comprehensiveness rating: 3 see less

While the book does touch upon many areas, the text reads more like a student notes packet and it fails to address the ecology side of biology. Ecology makes up one unit of my course, so this book would not work. The following is written on random pages throughout: "This text is based on notes very generously donated by Dr. Paul Doerder, Ph.D., of the Cleveland State University." So, it appears that is it really just intended to be a notes packet.

Content Accuracy rating: 2

The bulleted list "notes packet" of facts/topics is supported only by links to Wikipedia which is not really a source I would want to encourage students to use on a regular basis. I'm giving this a 2/5 primarily because of the lack of detail in the "text" and sole use of Wikipedia for diagrams and other information.

Relevance/Longevity rating: 2

This book relies on Wikipedia information to be up-to-date.

Clarity rating: 2

This isn't really written like a textbook, but more as a notes packet for students. Bare bones facts, no diagrams included in the text (just Wiki links). There would be some value to adding in transitional information to help tie together topics.

Consistency rating: 2

The style of "writing" is consistent. Bulleted list, outline format. Some pages/topics are blank, though.

Modularity rating: 2

Given that this is a notes packet, it is easily divisible into smaller sections, as a lecture might be. The missing information and the lack of details are both problems for me, though.

Organization/Structure/Flow rating: 2

Yes, but a lot of information is missing. For instance, Chapter 12's coverage of fermentation is virtually non-existent.

Interface rating: 1

The lack of diagrams within the text and use of Wikipedia links is a concern.

Grammatical Errors rating: 3

Much is written in bulleted notes format.

Cultural Relevance rating: 3

I didn't notice issues with cultural sensitivity.

Overall, this is not a "book" that I would use or recommend. The fact that it is just a notes packet and is missing a lot of detail, missing all diagrams that can help students understand processes, etc., makes it a no for me.

Reviewed by Nipun Chopra, Assistant Professor, DePauw University on 1/6/21

I think this textbook covers the breadth of Intro Biology well, but, certainly not in a deep enough way to help students along. read more

I think this textbook covers the breadth of Intro Biology well, but, certainly not in a deep enough way to help students along.

Most of the content is accurate, simply in how brief it is. However, there are significant problems which brings into question the validity of this textbook in Biology courses. Most notably, it considers “Special creation” as an equally valid hypothesis as natural selection, while it is not a hypothesis... as it is largely untestable. The text talks about Miller-Urey as “weak science” without recognizing the recent work at Indiana University confirming his methodology and conclusions. This segment should be re-written by someone who understands evolutionary theory and the Miller-Urey experiment better. It was also surprising to see the use of the word “disproved” in a Bio textbook.

Relevance/Longevity rating: 5

The textbook would be highly update-able as it relies significantly in students reading Wikipedia articles - which are being constantly updated.

Clarity rating: 3

This textbook is essentially aset of “notes” accompanied by hyperlinks to Wikipedia. There is not enough detail to educate students on important concepts. For example, “fluid mosaic”, is truncated to two sentences without any attached image. This is a notoriously confusing concept that cannot be understood by students without assistance visualizing it. Meanwhile, the section on cell organelles is more expansive - but still far too simplistic. Same overly-simplistic issue of understanding things like protein transport, different protein types, etc. On the other hand, the description of photosynthesis is concise, but informative. Similarly, Mendelian Genetics is described reasonably well, while X-inactivation - another potentially confusing concept - is described in one sentence. Chapter 23 and onwards are better, with students getting a flavor of biodiversity, tissue systems, body plans, basic animal physiology and anatomy in a succinct way.

Consistency rating: 3

The text is somewhat consistent in its format. But significant differences in level of depth across chapters.

Modularity rating: 4

The textbook is divided nicely into smaller areas of exploration.

Organization/Structure/Flow rating: 5

The flow of the textbook is as logical as any other Biology textbook. No complaints here.

Interface rating: 3

The figures seem rudimentary, and are certainly not high-resolution images.

Grammatical Errors rating: 5

No noticeable grammatical errors.

Not applicable

Reviewed by Ken Kruta, senior visiting lecturer, Bunker Hill Community College on 6/8/20

Although all of the important topics for an Intro to Bio course are listed as chapters, unfortunately, they are often missing information and details. read more

Comprehensiveness rating: 2 see less

Although all of the important topics for an Intro to Bio course are listed as chapters, unfortunately, they are often missing information and details.

The chapter references are simply Wikipedia pages.

It is from 2015 and used Wikipedia as references.

In many places it reads like simply a list of bullet points without enough explanation.

Some of the chapters change stylistic approaches as if collected from different sources/writers.

Modularity rating: 3

It is customizable, although incomplete in many sections.

Organization/Structure/Flow rating: 4

There is a logical flow between chapters.

Some of the images are of poor quality.

There are a few grammatical errors throughout the text.

Cultural Relevance rating: 1

Almost nonexistent, as info comes from Wikipedia.

I would not chose this as a primary text. One would need to supply significant supplemental material in order to cover the topics more completely.

Reviewed by Angela Nugent, Instructor, Northeastern Illinois University on 5/7/20

The text covers all of the important topics for an introductory biology course. However, the text is missing enough detail and explanation. Some sections were empty and didn't have any information. For most of the text, I felt as if I was reading... read more

The text covers all of the important topics for an introductory biology course. However, the text is missing enough detail and explanation. Some sections were empty and didn't have any information. For most of the text, I felt as if I was reading a vague outline/bullet points from lecture slide notes. Also, the glossary is incomplete and limited/short.

The text just references Wikipedia pages for information (e.g. cell components) instead of providing information in the chapter.

Copyright is 2015, so it's not the most up to date information. The information covers the bare basics though. Figures also appear outdated where some graphics are poor quality.

Some bullet points have no explanation provided. I think readers without a solid background in biology might have difficulty reading through the text. I'd be concerned that the professor might need to provide a lot more supplemental instruction/material for the lack of detail in the textbook. In addition, some bullet points and terms are not explained in the text or glossary. Instead the term is referenced to a Wikipedia page in some sections.

The framework between chapters is not consistent.

The writing style changes throughout the book, which I personally found disruptive and unfavorable. Some sections were bullet points, whereas others were paragraphs or short single sentences. Also the amount of information/detail varied per section. The various writing styles could maybe appeal to a wider variety of learners, but it was all too inconsistent for me.

Overall major topics flow in a logical order and were clear in how they were organized. Some sections didn't have any information though. So it wasn't clear why it was present, but didn't have any additional content.

Interface rating: 4

Some images are poor quality.

Grammatical errors were found.

Cultural Relevance rating: 2

The text really seems to just go over the bare basics. Examples are not really inclusive because examples are limited and sparse in general. I was really disappointed to not find more examples.

Reviewed by Sandra Yarema, Assistant Professor, Clinical, Wayne State University on 11/30/18

The book addresses all the important topic areas of biology, but does not provide much detailed information necessary to be the primary text for a comprehensive biology course. read more

The book addresses all the important topic areas of biology, but does not provide much detailed information necessary to be the primary text for a comprehensive biology course.

Content Accuracy rating: 3

Content is accurate, but limited. Using Wikipedia as a resource is not really best scientific practice.

Relevance/Longevity rating: 3

Content is up-to-date, not really detailed enough in cutting-edge discoveries to need updating.

Clarity rating: 4

Text is clear, but perhaps not enough detail provided for each topic. More diagrams would be useful.

Terminology and framework consistently adequate.

Modularity rating: 5

Chapters are organized in a way to easily subdivide into units of study.

Bullet points and topic designations are useful.

Interface adequate. Font could be larger.

No grammatical errors found.

Cultural Relevance rating: 4

No culturally insensitive or offensive material noted. Few inclusive examples provided.

This could be useful as a review for a general biology course or testing program. Not really detailed or comprehensive enough to use as the primary text for a biology course in a science-based program.

Reviewed by Nicholas Stewart, Instructor, Fort Hays State University on 11/29/18

The book does contain a comprehensive list of biological topics for an introductory biology class. However, the book lacks the detail required to be the primary textbook for students. It is a good outline for an introductory class for the... read more

The book does contain a comprehensive list of biological topics for an introductory biology class. However, the book lacks the detail required to be the primary textbook for students. It is a good outline for an introductory class for the instructor. The material is often presented in bullet points, which I don't have an issue with, but there needs to be more information to help connect those bullet points together to get a more complete picture. However, an instructor could use this as a guide and fill in the gaps themselves. Additionally, multiple of the Genetics sections and a couple of the later chapters appear to be incomplete.

Content Accuracy rating: 4

The majority of the information appears to be accurate. Noticed a few mistakes but nothing that could be fixed quickly by the instructor or authors.

Relevance/Longevity rating: 4

This book is a few years old, therefore new technologies could be added to help the relevance. Given the bullet point style of the text it could be done fairly easily.

The information is written in a way that students should be able to understand. However, the lack of connective text between different bullet points and/or topics will make it hard to form a complete picture of the major topics presented in the book. There isn't enough figures or examples supporting the text.

I pointed out the the inconsistency in the organization in the organization section. Not all topics headers have information associated with them.

I did not have an issue finding specific sections within the book. The outline style of the text makes it easy to find topics.

Organization/Structure/Flow rating: 3

I don't have an issue with the logical order of the topics. However, Section 6 "Cell" and Section 15 "Genetics" appear to be major headings and the following chapters are subsection of the major topic. The authors use of the same numbering between these headings and the other chapters makes for a slightly awkward flow.

The lack of figures makes the interface easy. The text is in a straightforward style, thus easy to read.

I did not find any glaring errors

I did not notice anything offensive. The lack of examples helps the text steer away from controversial topics.

This book I think is a helpful outline of an introductory course. It can help an instructor who is unsure about the topics that should be covered. It isn't comprehensive enough to be a stand alone resource for a class.

Reviewed by Erika Young, Lecturer, University of North Carolina at Pembroke on 6/19/18

While the text covers a multitude of topics, it doesn't give the details often required for thorough understanding. read more

Comprehensiveness rating: 4 see less

While the text covers a multitude of topics, it doesn't give the details often required for thorough understanding.

I do not agree with citing Wikipedia as a scientist, because of the ability to edit the information. I learned it was always best to use peer reviewed materials.

The text is more of a bulleted list of topics that doesn't seem to need the majority of the sub-categories and is sometimes redundant in placement of the material.

Very clear for general understanding. Not nearly enough diagrams/figures.

Consistency rating: 4

Text seems consistent but has details in some sections, and rather vague in others to be considered a general biology text.

Short bullet points help, and it seems very helpful as a study guide for something larger with more in depth discussions.

Flow was adequate.

Text was very clear, font perhaps could be larger.

No grammatical error found.

Not culturally insensitive or offensive.

Reviewed by Qing Li, Masters student, Oklahoma State University on 5/21/18

This book covers almost every topic that biology major students should know, however, it misses information in every topic. In another word, it tries to cover everything but failed to cover everything in detailed, especially it misses some... read more

This book covers almost every topic that biology major students should know, however, it misses information in every topic. In another word, it tries to cover everything but failed to cover everything in detailed, especially it misses some important information that a regular textbook should contain. It more looks like a study guide for test instead of a learning material. It tells you what type of information you should know, however, you probably have to search more detailed information in each unit somewhere else.

Content Accuracy rating: 5

Content appeared to be accurate for me. Probably it needs to be added more updated knowledge in a newer version.

This book is not up-dated as I mentioned above. It definitely can be added more update information as the progress of the technology. However, this book is easy to be updated by any instructors with newer and more information in their own manner due to the special structure of this book.

It does not contain enough information for most chapters and it doesn’t explain some concepts or jargons very clearly due to the shortness of this textbook. Some concepts should be explained with more words and sentences.

This textbook is somewhat inconsistent. As for the structure, some chapters contains more information than other chapters. In another word, some chapters use a bullets format, but the others use a paragraph format and try to explain more detailed information.

This book is very easy to be divided into smaller reading sections for sure due to its special structure. It is easy to reorganized and realigned by any instructor based on how he or she wants to structure his or her course.

The topics in the text are presented in a logical order, however, it can use more subunit under each chapter to make this textbook look more organized.

Interface rating: 2

This book does not contain too many figures. It might be a good way in some purpose, for example, you only want to use this book as a study guide. However, as a real textbook, it definitely needs more graphs and figures to improve the readability of this textbook.

I didn’t find much grammatical errors in this textbook.

Cultural Relevance rating: 5

This book is not culturally insensitive or offensive in any way. It doesn’t contain any examples can be regarded as racial discrimination.

This textbook can be good or bad for you depends on how you want to use it and in which way. It is more like a quick study review for general biology instead of a regular textbook. As I mentioned above, if you want to quickly go through every topic covered by general biology in a really basic level, this book can be useful for you. However, if you want more detailed information and use this book as a main textbook resource for your two semester length course, this book is not your best choice.

Reviewed by Haiying Liang, Associate Professor, Clemson University on 2/1/18

The text covers most subjects of general biology. Because it is very concise (using bullets in many places), not many information is included. The knowledge depth is not adequate for a real textbook. read more

The text covers most subjects of general biology. Because it is very concise (using bullets in many places), not many information is included. The knowledge depth is not adequate for a real textbook.

Content appears accurate. DNA sequencing section may need to be updated with next generation sequencing information.

Relevance/Longevity rating: 1

The text is too short. It does not contain enough information to be a textbook. It can be useful for quick review for exams.

Clarity rating: 1

Certain chapters and paragraphs are clear and contain enough information. However, most of the text does not contain enough information, largely due to the fact that this book is more like a summary of various topics in biology, not a real textbook.

The text is not consistent in terms of style, formatting, clarity, and information provided. For instance, only practice questions are provided for a couple of topics.

The text uses a bullet point style, which makes the modularity very clear. However, by doing so, lots of information is omitted.

The topics are divided into chapters only. It can be improved if the chapters are organized by units.

The text is not user friendly. Options are very limited.

Grammatical Errors rating: 4

There are some grammatical errors, such as misspellings, extra words or numbers, and incorrect use of plurals. Formats are not consistent.

The materials are not culturally sensitive

This book summarizes the main concepts in general biology. It can be used for preview and review purposes. The text is easy to read.

Reviewed by Allyse Ferrara, Professor, Nicholls State University on 2/15/17

This is not a comprehensive text. If all of the topics that are missing from this text were included in this review, the review would be as long as the text. The PDF is less than 200 pages long for what is typically taught in two one-semester... read more

Comprehensiveness rating: 1 see less

This is not a comprehensive text. If all of the topics that are missing from this text were included in this review, the review would be as long as the text. The PDF is less than 200 pages long for what is typically taught in two one-semester classes. Sufficient detail and background information is not provided. The entire PDF only includes six figures. In particular, information on diversity is incomplete with the majority of taxonomic levels and categories missing. For example, in Chapter 24 Chordates, information on Class Osteichthyes consists of a couple of sentences on Subclass Sarcopterygii. Ray-finned fishes are not included. Class Reptilia lists Subclass Diapsida under which there are four words – “dinosaurs, snakes, most stuff”. Only one half page of information is provided on Class Aves. Class Mammalia is covered in less than one page. Section 23.4 on Plant Phylogeny contains no text. Developmental biology, comparative physiology, ecology (at any level), behavior, endosymbiosis, plant anatomy and plant physiology are a few of the topics absent from the PDF. The glossary is half of a page with many definitions missing. No index is included.

Content Accuracy rating: 1

Text content is not accurate, error-free and unbiased. Very little organismal and diversity of life information is provided. Unfortunately, adequate and appropriate quantity of information is not provided for any topic. For example, in Chapter 7 Cell Structure, swelling is defined as “pressure of the water inside the vacuole” and isotonic is defined as “the cytoplasm fluid of the interior of the cells is the same that the outer”. Proof reading did not occur. Under the section 23.21 Angiosperm flower, the following text is included "Insert non-formatted text hereInsert non-formatted text here".

The PDF is outdated and no longer relevant. Old and outdated classification system(s) is/are used and the PDF uses outdated terms vascular and non-vascular to describe different groups of plants. An incomplete and outdated classification of Kingdom Animalia is used. Important plant, fungi and protist phyla are missing as are milestones in animal evolution and characteristics that allowed plants to colonize land. The minimal amount of biotechnology information included in the PDF is also outdated.

The PDF is loaded with jargon and is not well written.

Consistency rating: 1

The PDF is highly inconsistent. Scientific and genus names frequently appear in regular font (neither italicized nor underlined) and capitalization is not consistent. A few sections include complete sentences and paragraphs and the remaining sections contain no text or only bulleted lists. The majority of chapters do not practice questions. If practice questions are included, answers to questions are not consistently included, if at all. In some sections, references made to pages and figures in an unnamed textbook.

Modularity rating: 1

Modularity is not present. Sections and chapters are not presented in similar formats.

Organization/Structure/Flow rating: 1

Text organization is not logical. The text is not divided into units but would benefit by organization into units rather than using placeholder chapters as is used for Chapter 1 Getting Started, Chapter 6 Cells, Chapter 15 Genetics and Chapter 25 Tissues and Systems. No text included in these placeholder chapters. Information is not logically organized. For example, Chapter 13 on Photosynthesis includes unrelated sections on prokaryote cell division, eukaryote chromosomes, chromosome organization (no text included), human karyotype stained by chromosome paints (no text included), human chromosomes (a quarter page with a bulleted list), mitotic cell cycle (three bullets and one text box consisting of one sentence), replicated human chromosomes (no text included), mitosis (half page of information), plant mitosis (one quarter page), controlling the cell cycle, cancer and mutations and cancer (no text included). The glossary (Chapter 34) is half of a page with some terms undefined. The list of figures does not correspond to the six figures included in the text.

Some of the links in the footnotes connect to Wikibooks pages that do not contain any information. After connecting to a Wikibooks link, clicking the back arrow brings you to the beginning of the PDF, not to the section you were reading. Navigation between footnotes and text is cumbersome.

Grammatical Errors rating: 1

The text is filled with misspellings, incorrect word use, jargon, incorrect use of plurals, grammatical errors, incomplete sentences and statements without explanation or support.

Considering the brevity of information provided the text is not culturally sensitive. The term “man” is used rather than the more appropriate term “human”.

This is not a textbook. The information provided is incomplete and outdated and is little more than an incomplete and unedited draft of course notes.

Reviewed by Takamitsu Kato, Associate Professor, Colorado State University on 12/5/16

This open book is very comprehensive, however, I believe that the context of the book may be too comprehensive. Moreover, the text covers very broad fields of biology that students may not be able to grasp. However, the text is not in a... read more

This open book is very comprehensive, however, I believe that the context of the book may be too comprehensive. Moreover, the text covers very broad fields of biology that students may not be able to grasp. However, the text is not in a traditional style, meaning that it contains less than 200 pages. Therefore, students will not get in depth knowledge. Some chapters appear to be incomplete.

The book appeared to be accurate. More specifically, the paragraphs, sentences, and phrases are very short resulting in great accuracy. Moreover, students can learn many topics very quickly and efficiently. Lastly, I noticed some mistakes but they were minor problems.

Importantly, this book is very up-to-date and can be updated quickly if authors want. On-the-other-hand various chapters seem to be incomplete or too short (i.e. section 8.3.2). But the unique style of this book enables authors to update information easily.

Clarity rating: 5

The text was written very clearly, while the book is very short. It is very easy to read but scholars need prerequisite information before reading the material in this book.

The text is usually consistent but there are some exceptions. Many chapters were written with bullet points and short sentences. However, a few chapters were written with more information; leaving inconsistencies . The inconsistencies can be improved by further updates.

The text is very easily divisible. The text can be used for just quick review but not for extensive information. If the authors decide to keep the bullet point style this could be useful for students early in the biology world.

The book is divided into many chapters and subchapters. The topics in the text are presented in a very clear fashion. Individual chapters are appropriately organized.

The text sometimes contains graphical figures but additional figures would greatly improve the context. However, if the purpose of this book is quick review, the figures and charts are not necessary.

I did not notice any grammatical errors.

The text is not culturally insensitive or offensive.

This book is very unique. It is not like regular books. It is more like a summary of wikipedia's knowledge on biology. This book is very useful to review what students learned in class or try to understand the concept quickly before class starts. Reading this text does not take too much time. Personally, I like this book. I can use this as a quick reference. For class this book can be used as an alternative book with combination of traditional general biology book. This book would be a great alternative for students who are trying to be fiscally smart.

Table of Contents

• 1 Getting Started
• 2 Biology - The Life Science
• 3 The Nature of Molecules
• 4 Chemical Building Blocks of Life
• 5 Life: History and Origin
• 7 Cell structure
• 8 Structure of Eukaryotic cells
• 9 Membranes
• 10 Cell-cell interactions
• 11 Energy and Metabolism
• 12 Respiration: harvesting of energy
• 13 Photosynthesis
• 14 Sexual reproduction
• 15 Genetics
• 16 Gregor Mendel and biological inheritance
• 17 DNA: The Genetic Material
• 18 Gene expression
• 19 Gene regulation
• 20 Mutation
• 21 Recombinant DNA technology
• 22 Classification of Living Things
• 23 Multicellular Photosynthetic Autotrophs
• 24 Chordates
• 25 Tissues and Systems
• 26 Epithelial tissue
• 27 Connective tissue
• 28 Muscle tissue
• 29 Vertebrate digestive system
• 30 Circulatory system
• 31 Respiratory system
• 32 Sensory systems
• 33 Additional material
• 34 Glossary
• 35 Contributors
• 36 Licenses

Ancillary Material

About the book.

The word biology means, "the science of life", from the Greek bios, life, and logos, wordor knowledge. Therefore, Biology is the science of Living Things. That is why Biology issometimes known as Life Science.

About the Contributors

Paul Doerder is a biology professor at Cleveland State University located in Cleveland, Ohio. 

Ralph Gibson   is an assistant professor at Cleveland State University located in Cleveland, Ohio. 

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Biology library

Welcome to the biology library, unit 1: intro to biology, unit 2: chemistry of life, unit 3: water, acids, and bases, unit 4: properties of carbon, unit 5: macromolecules, unit 6: elements of life, unit 7: energy and enzymes, unit 8: structure of a cell, unit 9: more about cells, unit 10: membranes and transport, unit 11: more about membranes, unit 12: cellular respiration, unit 13: photosynthesis, unit 14: cell signaling, unit 15: cell division, unit 16: classical and molecular genetics, unit 17: dna as the genetic material, unit 18: central dogma (dna to rna to protein), unit 19: gene regulation, unit 20: biotechnology, unit 21: more molecular biology, unit 22: developmental biology, unit 23: bacteria and archaea, unit 24: viruses, unit 25: evolution and the tree of life, unit 26: more about evolution and natural selection, unit 27: history of life on earth, unit 28: ecology, unit 29: more about ecology, unit 30: biodiversity and conservation, unit 31: behavioral biology, unit 32: principles of physiology, unit 33: human biology, unit 34: plant biology, unit 35: ap free response worked examples, unit 36: crash course: biology and ecology, unit 37: meet the biology professional.

• USF Research
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Digital Commons @ USF > College of Arts and Sciences > Molecular Biosciences > Theses and Dissertations

Molecular Biosciences Theses and Dissertations

Theses/dissertations from 2023 2023.

Exploring strain variation and bacteriophage predation in the gut microbiome of Ciona robusta , Celine Grace F. Atkinson

Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression , Janine M. DeBlasi

Thermodynamic frustration of TAD2 and PRR contribute to autoinhibition of p53 , Emily Gregory

Utilization of Detonation Nanodiamonds: Nanocarrier for Gene Therapy in Non-Small Cell Lung Cancer , Allan E. Gutierrez

Role of HLA-DRB1 Fucosylation in Anti-Melanoma Immunity , Daniel K. Lester

Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML , Christopher T. Letson

Regulated Intramembrane Proteolysis by M82 Peptidases: The Role of PrsS in the Staphylococcus aureus Stress Response , Baylie M. Schott

Histone Deacetylase 8 is a Novel Therapeutic Target for Mantle Cell Lymphoma and Preserves Natural Killer Cell Cytotoxic Function , January M. Watters

Theses/Dissertations from 2022 2022

Regulation of the Heat Shock Response via Lysine Acetyltransferase CBP-1 and in Neurodegenerative Disease in Caenorhabditis elegans , Lindsey N. Barrett

Determining the Role of Dendritic Cells During Response to Treatment with Paclitaxel/Anti-TIM-3 , Alycia Gardner

Cell-free DNA Methylation Signatures in Cancer Detection and Classification , Jinyong Huang

The Role Of Eicosanoid Metabolism in Mammalian Wound Healing and Inflammation , Kenneth D. Maus

A Holistic Investigation of Acidosis in Breast Cancer , Bryce Ordway

Characterizing the Impact of Postharvest Temperature Stress on Polyphenol Profiles of Red and White-Fruited Strawberry Cultivars , Alyssa N. Smith

Theses/Dissertations from 2021 2021

Multifaceted Approach to Understanding Acinetobacter baumannii Biofilm Formation and Drug Resistance , Jessie L. Allen

Cellular And Molecular Alterations Associated with Ovarian and Renal Cancer Pathophysiology , Ravneet Kaur Chhabra

Ecology and diversity of boletes of the southeastern United States , Arian Farid

CircREV1 Expression in Triple-Negative Breast Cancer , Meagan P. Horton

Microbial Dark Matter: Culturing the Uncultured in Search of Novel Chemotaxonomy , Sarah J. Kennedy

The Multifaceted Role of CCAR-1 in the Alternative Splicing and Germline Regulation in Caenorhabditis elegans , Doreen Ikhuva Lugano

Unraveling the Role of Novel G5 Peptidase Family Proteins in Virulence and Cell Envelope Biogenesis of Staphylococcus aureus , Stephanie M. Marroquin

Cytoplasmic Polyadenylation Element Binding Protein 2 Alternative Splicing Regulates HIF1α During Chronic Hypoxia , Emily M. Mayo

Transcriptomic and Functional Investigation of Bacterial Biofilm Formation , Brooke R. Nemec

A Functional Characterization of the Omega (ω) subunit of RNA Polymerase in Staphylococcus aureus , Shrushti B. Patil

The Role Of Cpeb2 Alternative Splicing In TNBC Metastasis , Shaun C. Stevens

Screening Next-generation Fluorine-19 Probe and Preparation of Yeast-derived G Proteins for GPCR Conformation and Dynamics Study , Wenjie Zhao

Theses/Dissertations from 2020 2020

Understanding the Role of Cereblon in Hematopoiesis Through Structural and Functional Analyses , Afua Adutwumwa Akuffo

To Mid-cell and Beyond: Characterizing the Roles of GpsB and YpsA in Cell Division Regulation in Gram-positive Bacteria , Robert S. Brzozowski

Spatiotemporal Changes of Microbial Community Assemblages and Functions in the Subsurface , Madison C. Davis

New Mechanisms That Regulate DNA Double-Strand Break-Induced Gene Silencing and Genome Integrity , Dante Francis DeAscanis

Regulation of the Heat Shock Response and HSF-1 Nuclear Stress Bodies in C. elegans , Andrew Deonarine

New Mechanisms that Control FACT Histone Chaperone and Transcription-mediated Genome Stability , Angelo Vincenzo de Vivo Diaz

Targeting the ESKAPE Pathogens by Botanical and Microbial Approaches , Emily Dilandro

Succession in native groundwater microbial communities in response to effluent wastewater , Chelsea M. Dinon

Role of ceramide-1 phosphate in regulation of sphingolipid and eicosanoid metabolism in lung epithelial cells , Brittany A. Dudley

Allosteric Control of Proteins: New Methods and Mechanisms , Nalvi Duro

Microbial Community Structures in Three Bahamian Blue Holes , Meghan J. Gordon

A Novel Intramolecular Interaction in P53 , Fan He

The Impact of Myeloid-Mediated Co-Stimulation and Immunosuppression on the Anti-Tumor Efficacy of Adoptive T cell Therapy , Pasquale Patrick Innamarato

Investigating Mechanisms of Immune Suppression Secondary to an Inflammatory Microenvironment , Wendy Michelle Kandell

Posttranslational Modification and Protein Disorder Regulate Protein-Protein Interactions and DNA Binding Specificity of p53 , Robin Levy

Mechanistic and Translational Studies on Skeletal Malignancies , Jeremy McGuire

Novel Long Non-Coding RNA CDLINC Promotes NSCLC Progression , Christina J. Moss

Genome Maintenance Roles of Polycomb Transcriptional Repressors BMI1 and RNF2 , Anthony Richard Sanchez IV

The Ecology and Conservation of an Urban Karst Subterranean Estuary , Robert J. Scharping

Biological and Proteomic Characterization of Cornus officinalis on Human 1.1B4 Pancreatic β Cells: Exploring Use for T1D Interventional Application , Arielle E. Tawfik

Evaluation of Aging and Genetic Mutation Variants on Tauopathy , Amber M. Tetlow

Theses/Dissertations from 2019 2019

Investigating the Proteinaceous Regulome of the Acinetobacter baumannii , Leila G. Casella

Functional Characterization of the Ovarian Tumor Domain Deubiquitinating Enzyme 6B , Jasmin M. D'Andrea

Integrated Molecular Characterization of Lung Adenocarcinoma with Implications for Immunotherapy , Nicholas T. Gimbrone

The Role of Secreted Proteases in Regulating Disease Progression in Staphylococcus aureus , Brittney D. Gimza

Advanced Proteomic and Epigenetic Characterization of Ethanol-Induced Microglial Activation , Jennifer Guergues Guergues

Understanding immunometabolic and suppressive factors that impact cancer development , Rebecca Swearingen Hesterberg

Biochemical and Proteomic Approaches to Determine the Impact Level of Each Step of the Supply Chain on Tomato Fruit Quality , Robert T. Madden

Enhancing Immunotherapeutic Interventions for Treatment of Chronic Lymphocytic Leukemia , Kamira K. Maharaj

Characterization of the Autophagic-Iron Axis in the Pathophysiology of Endometriosis and Epithelial Ovarian Cancers , Stephanie Rockfield

Understanding the Influence of the Cancer Microenvironment on Metabolism and Metastasis , Shonagh Russell

Modeling of Interaction of Ions with Ether- and Ester-linked Phospholipids , Matthew W. Saunders

Novel Insights into the Multifaceted Roles of BLM in the Maintenance of Genome Stability , Vivek M. Shastri

Conserved glycine residues control transient helicity and disorder in the cold regulated protein, Cor15a , Oluwakemi Sowemimo

A Novel Cytokine Response Modulatory Function of MEK Inhibitors Mediates Therapeutic Efficacy , Mengyu Xie

Novel Strategies on Characterizing Biologically Specific Protein-protein Interaction Networks , Bi Zhao

Theses/Dissertations from 2018 2018

Characterization of the Transcriptional Elongation Factor ELL3 in B cells and Its Role in B-cell Lymphoma Proliferation and Survival , Lou-Ella M.m. Alexander

Identification of Regulatory miRNAs Associated with Ethanol-Induced Microglial Activation Using Integrated Proteomic and Transcriptomic Approaches , Brandi Jo Cook

Molecular Phylogenetics of Floridian Boletes , Arian Farid

MYC Distant Enhancers Underlie Ovarian Cancer Susceptibility at the 8q24.21 Locus , Anxhela Gjyshi Gustafson

Quantitative Proteomics to Support Translational Cancer Research , Melissa Hoffman

A Systems Chemical Biology Approach for Dissecting Differential Molecular Mechanisms of Action of Clinical Kinase Inhibitors in Lung Cancer , Natalia Junqueira Sumi

Investigating the Roles of Fucosylation and Calcium Signaling in Melanoma Invasion , Tyler S. Keeley

Synthesis, Oxidation, and Distribution of Polyphenols in Strawberry Fruit During Cold Storage , Katrina E. Kelly

Investigation of Alcohol-Induced Changes in Hepatic Histone Modifications Using Mass Spectrometry Based Proteomics , Crystina Leah Kriss

Off-Target Based Drug Repurposing Using Systems Pharmacology , Brent M. Kuenzi

Investigation of Anemarrhena asphodeloides and its Constituent Timosaponin-AIII as Novel, Naturally Derived Adjunctive Therapeutics for the Treatment of Advanced Pancreatic Cancer , Catherine B. MarElia

The Role of Phosphohistidine Phosphatase 1 in Ethanol-induced Liver Injury , Daniel Richard Martin

Theses/Dissertations from 2017 2017

Changing the Pathobiological Paradigm in Myelodysplastic Syndromes: The NLRP3 Inflammasome Drives the MDS Phenotype , Ashley Basiorka

Modeling of Dynamic Allostery in Proteins Enabled by Machine Learning , Mohsen Botlani-Esfahani

Uncovering Transcriptional Activators and Targets of HSF-1 in Caenorhabditis elegans , Jessica Brunquell

The Role of Sgs1 and Exo1 in the Maintenance of Genome Stability. , Lillian Campos-Doerfler

Mechanisms of IKBKE Activation in Cancer , Sridevi Challa

Discovering Antibacterial and Anti-Resistance Agents Targeting Multi-Drug Resistant ESKAPE Pathogens , Renee Fleeman

Functional Roles of Matrix Metalloproteinases in Bone Metastatic Prostate Cancer , Jeremy S. Frieling

Disorder Levels of c-Myb Transactivation Domain Regulate its Binding Affinity to the KIX Domain of CREB Binding Protein , Anusha Poosapati

Role of Heat Shock Transcription Factor 1 in Ovarian Cancer Epithelial-Mesenchymal Transition and Drug Sensitivity , Chase David Powell

Cell Division Regulation in Staphylococcus aureus , Catherine M. Spanoudis

A Novel Approach to the Discovery of Natural Products From Actinobacteria , Rahmy Tawfik

Non-classical regulators in Staphylococcus aureus , Andy Weiss

Theses/Dissertations from 2016 2016

In Vitro and In Vivo Antioxidant Capacity of Synthetic and Natural Polyphenolic Compounds Identified from Strawberry and Fruit Juices , Marvin Abountiolas

Quantitative Proteomic Investigation of Disease Models of Type 2 Diabetes , Mark Gabriel Athanason

CMG Helicase Assembly and Activation: Regulation by c-Myc through Chromatin Decondensation and Novel Therapeutic Avenues for Cancer Treatment , Victoria Bryant

Computational Modeling of Allosteric Stimulation of Nipah Virus Host Binding Protein , Priyanka Dutta

Cell Cycle Arrest by TGFß1 is Dependent on the Inhibition of CMG Helicase Assembly and Activation , Brook Samuel Nepon-Sixt

Gene Expression Profiling and the Role of HSF1 in Ovarian Cancer in 3D Spheroid Models , Trillitye Paullin

VDR-RIPK1 Interaction and its Implications in Cell Death and Cancer Intervention , Waise Quarni

Regulation of nAChRs and Stemness by Nicotine and E-cigarettes in NSCLC , Courtney Schaal

Targeting Histone Deacetylases in Melanoma and T-cells to Improve Cancer Immunotherapy , Andressa Sodre De Castro Laino

Nonreplicative DNA Helicases Involved in Maintaining Genome Stability , Salahuddin Syed

Theses/Dissertations from 2015 2015

Functional Analysis of the Ovarian Cancer Susceptibility Locus at 9p22.2 Reveals a Transcription Regulatory Network Mediated by BNC2 in Ovarian Cells , Melissa Buckley

Exploring the Pathogenic and Drug Resistance Mechanisms of Staphylococcus aureus , Whittney Burda

Regulation and Targeting of the FANCD2 Activation in DNA Repair , Valentina Celeste Caceres

Mass Spectrometry-Based Investigation of APP-Dependent Mechanisms in Neurodegeneration , Dale Chaput

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Home > CNS > BIOCHEM > MCB > MCB_THESES

Molecular and Cellular Biology Masters Theses Collection

Theses from 2024 2024.

The Impact of a Non-ionic Adjuvant to the Persistence of Pesticides on Produce Surfaces , Daniel Barnes, Molecular & Cellular Biology

Investigating the Role of Got2 in Murine Organogenesis and Placenta Development , Olivia Macrorie, Molecular & Cellular Biology

Chromatin Accessibility Impacts Knockout of Mt-Bell4 Transcription Factor , Thomas Redden, Molecular & Cellular Biology

UNDERSTANDING THE FUNCTIONAL IMPACT OF DISEASE-ASSOCIATED PHOSPHORYLATION SITES ON THE NEURODEGENERATIVE PROTEIN TAU , Navya T. Sebastian, Molecular & Cellular Biology

Theses from 2023 2023

Elucidating the Priming Mechanism of ClpXP Protease by Single-Domain Response Regulator CpdR in Caulobacter crescentus , Kimberly E. Barker, Molecular & Cellular Biology

The Discovery of a Novel Bacteria from a Large Co-assembly of Metagenomes , Matthew Finkelberg, Molecular & Cellular Biology

Investigating Diterpene Biosynthesis in Medicago Truncatula , Sungwoo Hwang, Molecular & Cellular Biology

Combining Simulation and the MspA Nanopore to Study p53 Dynamics and Interactions , Samantha A. Schultz, Molecular & Cellular Biology

Caulobacter ClpXP Adaptor PopA’s Domain Interactions in the Adaptor Hierarchy of CtrA Degradation , Thomas P. Scudder, Molecular & Cellular Biology

Climate Change, Giant Viruses and Their Putative Hosts , Sarah K. Tucker, Molecular & Cellular Biology

Theses from 2022 2022

Changes in Gene Expression From Long-Term Warming Revealed Using Metatranscriptome Mapping to FAC-Sorted Bacteria , Christopher A. Colvin, Molecular & Cellular Biology

Determining CaMKII Variant Activities and Their Roles in Human Disease , Matthew J. Dunn, Molecular & Cellular Biology

Developmental Exposures to PFAS Mixtures Impair Elongation of the Exocrine Pancreas in Zebrafish (Danio rerio) , Emily M. Formato, Molecular & Cellular Biology

A Metatranscriptomic Analysis of the Long-Term Effects of Warming on the Harvard Forest Soil Microbiome , Brooke A. Linnehan, Molecular & Cellular Biology

Characterization of the Poly (ADP-Ribose) Polymerase Family in the Fusarium oxysporum Species Complex , Daniel Norment, Molecular & Cellular Biology

Theses from 2021 2021

Exploring Knockdown Phenotypes and Interactions between ATAD3 Proteins in Arabidopsis thaliana , Eli S. Gordon, Molecular & Cellular Biology

Development of a Site-Specific Labeling Assay to Study the Pseudomonas aeruginosa Type III Secretion Translocon in Native Membranes , Kyle A. Mahan, Molecular & Cellular Biology

Liposomal Nanoparticles Target TLR7/8-SHP2 to Repolarize Macrophages to Aid in Cancer Immunotherapy , Vaishali Malik, Molecular & Cellular Biology

Hsp70 Phosphorylation: A Case Study of Serine Residues 385 and 400 , Sashrika Saini, Molecular & Cellular Biology

Activation of Nrf2 at Critical Windows of Development Alters Protein S-Glutathionylation in the Zebrafish Embryo (Danio rerio) , Emily G. Severance, Molecular & Cellular Biology

Utilizing Fluorescence Microscopy to Characterize the Subcellular Distribution of the Novel Protein Acheron , Varun Sheel, Molecular & Cellular Biology

Theses from 2020 2020

The Association Between Sperm DNA Methylation and Sperm Mitochondrial DNA Copy Number , Emily Houle, Molecular & Cellular Biology

Gene Expression Regulation in the Mouse Liver by Mechanistic Target Of Rapamycin Complexes I and II , Anthony Poluyanoff, Molecular & Cellular Biology

Sperm Mitochondrial DNA Biomarkers as a Measure of Male Fecundity and Overall Sperm Quality , Allyson Rosati, Molecular & Cellular Biology

Exploration of the Association between Muscle Volume and Bone Geometry Reveals Surprising Relationship at the Genetic Level , Prakrit Subba, Molecular & Cellular Biology

Theses from 2019 2019

Studies on the Interaction and Organization of Bacterial Proteins on Membranes , Mariana Brena, Molecular & Cellular Biology

Investigating The Role Of LBH During Early Embryonic Development In Xenopus Laevis , Emma Weir, Molecular & Cellular Biology

Theses from 2018 2018

Exploring the Influence of PKC-theta Phosphorylation on Notch1 Activation and T Helper Cell Differentiation , Grace Trombley, Molecular & Cellular Biology

Theses from 2017 2017

Partial Craniofacial Cartilage Rescue in ace/fgf8 Mutants from Compensatory Signaling From the Ventricle of Danio Rerio , Douglas A. Calenda II, Molecular & Cellular Biology

THE FAR C-TERMINUS OF TPX2 CONTRIBUTES TO SPINDLE MORPHOGENESIS , Brett Estes, Molecular & Cellular Biology

Characterization of Calcium Homeostasis Parameters in TRPV3 and CaV3.2 Double Null Mice , Aujan Mehregan, Molecular & Cellular Biology

Microtransplantation of Rat Brain Neurolemma into Xenopus Laevis Oocytes to Study the Effect of Environmental Toxicants on Endogenous Voltage-Sensitive Ion Channels , Edwin Murenzi, Molecular & Cellular Biology

Regulation of Katanin Activity on Microtubules , Madison A. Tyler, Molecular & Cellular Biology

Theses from 2016 2016

The Role of MicroRNAs in Regulating the Translatability and Stability of Target Messenger RNAs During the Atrophy and Programmed Cell Death of the Intersegmental Muscles of the Tobacco Hawkmoth Manduca sexta. , Elizabeth Chan, Molecular & Cellular Biology

An in Vivo Study of Cortical Dynein Dynamics and its Contribution to Microtubule Sliding in the Midzone , Heather M. Jordan, Molecular & Cellular Biology

A Genetic Analysis of Cichlid Scale Morphology , Kenta C. Kawasaki, Molecular & Cellular Biology

Modulation of Notch in an Animal Model of Multiple Sclerosis , Manit Nikhil Munshi, Molecular & Cellular Biology

One-Carbon Metabolism Related B-Vitamins Alter The Expression Of MicroRNAS And Target Genes Within The Wnt Signaling Pathway In Mouse Colonic Epithelium , Riccardo Racicot, Molecular & Cellular Biology

Characterizing the Inhibition of Katanin Using Tubulin Carboxy-Terminal Tail Constructs , Corey E. Reed, Molecular & Cellular Biology

The Identification of Notch1 Functional Domains Responsible for its Physical Interaction with PKCθ , Wesley D. Rossiter, Molecular & Cellular Biology

Dynamics of Microtubule Networks with Antiparallel Crosslinkers , Kasimira T. Stanhope, Molecular & Cellular Biology

Modifications of Myofilament Structure and Function During Global Myocardial Ischemia , Mike K. Woodward, Molecular & Cellular Biology

Theses from 2015 2015

Regulation of Jak1 and Jak2 Synthesis through Non-Classical Progestin Receptors , Hillary Adams, Molecular & Cellular Biology

Antineoplastic Effects of Rhodiola Crenulata on B16-F10 Melanoma , Maxine Dudek, Molecular & Cellular Biology

RNAi Validation of Resistance Genes and Their Interactions in the Highly DDT-Resistant 91-R Strain of Drosophila Melanogaster , Kyle Gellatly, Molecular & Cellular Biology

Characterization of Protein-Protein Interactions for Therapeutic Drug Design Utilizing Mass Spectrometry , Alex J. Johnson, Molecular & Cellular Biology

Promoting Extracellular Matrix Crosslinking in Synthetic Hydrogels , Marcos M. Manganare, Molecular & Cellular Biology

Characterization of the Reconstituted and Native Pseudomonas aeruginosa Type III Secretion System Translocon , Kathryn R. Monopoli, Molecular & Cellular Biology

Thermocycle-regulated WALL REGULATOR INTERACTING bHLH Encodes a Protein That Interacts with Secondary-Cell-Wall-Associated Transcription Factors , Ian P. Whitney, Molecular & Cellular Biology

Theses from 2014 2014

Engineering Camelina sativa for Biofuel Production via increasing oil yield and tolerance to abiotic stresses , Kenny Ablordeppey, Molecular & Cellular Biology

Designing a Pore-Forming Toxin Cytolysin A (ClyA) Specific to Target Cancer Cells , Alzira Rocheteau Avelino, Molecular & Cellular Biology

The Role of the Novel Lupus Antigen, Acheron, in Moderating Life and Death Decisions , Ankur Sheel, Molecular & Cellular Biology

Expression and Purification of Human Lysosomal β-galactosidase from Pichia Pastoris , Sarah E. Tarullo, Molecular & Cellular Biology

Properties of Potential Substrates of a Cyanobacterial Small Heat Shock Protein , Yichen Zhang, Molecular & Cellular Biology

Theses from 2013 2013

Characterizing the Heavy Metal Chelator, Tpen, as a Ca2+ Tool in the Mammalian Oocyte , Robert A. Agreda Mccaughin, Molecular & Cellular Biology

Sustainable Biofuels Production Through Understanding Fundamental Bacterial Pathways Involved in Biomass Degradation and Sugar Utilization , James CM Hayes, Molecular & Cellular Biology

Stiffness and Modulus and Independent Controllers of Breast Cancer Metastasis , Dannielle Ryman, Molecular & Cellular Biology

Theses from 2012 2012

The Pyrethroid Deltamethrin, Which Causes Choreoathetosis with Salivation (CS-Syndrome), Enhances Calcium Ion Influx via Phosphorylated CaV2.2 expresssed in Xenopus laevis oocytes , Anna-maria Alves, Molecular & Cellular Biology

A Test of the Hypothesis That Environmental Chemicals Interfere With Thyroid Hormone Action in Human Placenta , Katherine Geromini, Molecular & Cellular Biology

Analyzing the Role of Reactive Oxygen Species in Male-Female Interactions in Arabidopsis thaliana. , Eric A. Johnson, Molecular & Cellular Biology

Rhythmic Growth And Vascular Development In Brachypodium Distachyon , Dominick A. Matos, Molecular & Cellular Biology

Polymer Prodrug Conjugation to Tumor Homing Mesenchymal Stem Cells , Nick Panzarino, Molecular & Cellular Biology

Investigation of Differential Vector Competence of Bartonella quintana in Human Head and Body Lice , Domenic j. Previte, Molecular & Cellular Biology

Downregulation of Cinnamyl Alcohol Dehydrogenase or Caffeic Acid O-Methyltransferase Leads to Improved Biological Conversion Efficiency in Brachypodium distachyon , Gina M. Trabucco, Molecular & Cellular Biology

Theses from 2011 2011

Evolutionary Relationship of the ampC Resistance Gene In E. cloacae , Shanika S. Collins, Molecular & Cellular Biology

Sex Difference in Calbindin Cell Number in the Mouse Preoptic Area: Effects of Neonatal Estradiol and Bax Gene Deletion , Richard F. Gilmore III, Molecular & Cellular Biology

In Vivo Investigations of Polymer Conjugates as Therapeutics , Elizabeth M. Henchey, Molecular & Cellular Biology

Examination of Sexually Dimorphic Cell Death in the Pubertal Mouse Brain , Amanda Holley, Molecular & Cellular Biology

Human Niemann-Pick Type C2 Disease Protein Expression, Purification and Crystallization , Yurie T. Kim, Molecular & Cellular Biology

Revealing the Localization of the Class I Formin Family in the Moss Physcomitrella patens Using Gene Targeting Strategies , Kelli Pattavina, Molecular & Cellular Biology

Connecting Motors and Membranes: A Quantitative Investigation of Dynein Pathway Components and in vitro Characterization of the Num1 Coiled Coil Domain , Bryan J. St. Germain, Molecular & Cellular Biology

Theses from 2010 2010

The Protective Effects A Full-term Pregnancy Plays Against Mammary Carcinoma , Matthew p. Carter, Molecular & Cellular Biology

Analysis Of An Actin Binding Guanine Exchange Factor, Gef8, And Actin Depolymerizing Factor In Arabidopsis Thaliana. , Aleksey Chudnovskiy, Molecular & Cellular Biology

The Role of Ykl-40, a Secreted Heparin-Binding Glycoprotein, in Tumor Angiogenesis, Metastasis, and Progression: a Potential Therapeutic Target , Michael Faibish, Molecular & Cellular Biology

In Vivo Visualization of Hedgehog Signaling in Zebrafish , Christopher J. Ferreira, Molecular & Cellular Biology

An In Vivo Study of the Mammalian Mitotic Kinesin Eg5 , Alyssa D. Gable, Molecular & Cellular Biology

Identification of Dynein Binding Sites in Budding Yeast Pac1/LIS1 , Christopher W. Meaden, Molecular & Cellular Biology

Functional Characterization of Arabidopsis Formin Homologues Afh1, Afh5, Afh6, Afh7 and Afh8 , Shahriar Niroomand, Molecular & Cellular Biology

Regulation of Crbp1 In Mammary Epithelial Cells , Stacy L. Pease, Molecular & Cellular Biology

In Vivo Labeling Of A Model β-Clam Protein With A Fluorescent Amino Acid , Mangayarkarasi Periasamy, Molecular & Cellular Biology

In Vivo Characterization of Interactions Among Dynein Complex Components at Microtubule Plus Ends , Karen M. Plevock, Molecular & Cellular Biology

Anti-Diabetic Potentials of Phenolic Enriched Chilean Potato and Select Herbs of Apiaceae and Lamiaceae Families , Fahad Saleem, Molecular & Cellular Biology

Interconversion of the Specificities of Human Lysosomal Enzymes , Ivan B. Tomasic, Molecular & Cellular Biology

Deletions of Fstl3 and/or Fst Isoforms 303 and 315 Results in Hepatic Steatosis , Nathan A. Ungerleider, Molecular & Cellular Biology

Theses from 2009 2009

A New Laser Pointer Driven Optical Microheater for Precise Local Heat Shock , Mike Placinta, Molecular & Cellular Biology

Theses from 2008 2008

Cysteine Dioxygenase: The Importance of Key Residues and Insight into the Mechanism of the Metal Center , Jonathan H. Leung, Molecular & Cellular Biology

Invertebrate Phenology and Prey Selection of Three Sympatric Species of Salmonids; Implications for Individual Fish Growth , Jeffrey V. Ojala, Wildlife & Fisheries Conservation

Paralemmin Splice Variants and mRNA and Protein Expression in Breast Cancer , Casey M. Turk, Molecular & Cellular Biology

Stability of the frog motor nerve terminal: roles of perisynaptic Schwann cells and muscle fibers , Ling Xin, Molecular & Cellular Biology

Theses from 2007 2007

Antioxidant Response Mechanism in Apples during Post-Harvest Storage and Implications for Human Health Benefits , Ishan Adyanthaya, Molecular & Cellular Biology

Progress Towards A Model Flavoenzyme System , Kevin M. Bardon, Molecular & Cellular Biology

The effect of Rhodiola crenulata on a highly metastatic murine mammary carcinoma , Jessica L. Doerner, Molecular & Cellular Biology

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150 Actual Biology Research Paper Topics

Table of contents

• 1 What Is Biology? What Topics Might Biologists Study?
• 2 How to Choose a Topic for Biology Research Paper?
• 3.1 15 Developmental Biology Topics For Research
• 3.2 15 Immune System Biology Research Topics
• 3.3 15 Cell Biology Research Topics
• 3.4 15 DNA Research Topics
• 3.5 15 Molecular Biology Research Topics
• 3.6 15 Neurobiology Research Topics
• 3.7 15 Abortion, Human cloning, and Genetic Researches Topics
• 3.8 15 Environmental and Ecology Topics for Your Research
• 3.9 15 Plant Pathology Biology Research Topics
• 3.10 15 Animals Biology Research Topics
• 3.11 15 Marine Biology Research Topics
• 3.12 15 Zoology Research Topics
• 3.13 15 Genetics Research Topics
• 3.14 15 Biotechnology Research Topics
• 3.15 15 Evolutionary Biology Research Topics

Biology is one of the most magnetic fields of study these days. If you want to be a biologist or scientist in the future, there is no better time to start than right now. Biology research topics covered in this article will keep you busy and interested. Writing a research paper is one of the best ways to dip your toes into the field. Before doing that, you need to know some good topics for the research paper . They should be suitable for biology students rather than cutting-edge researchers. On Papersowl.com , we provide as many biology research paper examples as possible so that you have a huge choice.

What Is Biology? What Topics Might Biologists Study?

Biology is simply the study of everything that has a form of life. It includes investigations on plants, animals, and everything found in the environment. It is about studying how life forms grow, develop, and interact with each other. Biology essay topics for research encompass all these and more.

This science uncovers many fields where various life forms are studied. It makes sense to look through these fields to help you decide which suits you the best.

Plant Biology research topics are about studying the plants around us. They disclose information about their existence as a part of the ecosystem, their life cycle, resources they can give us, their ability to preserve them from climate changes, and so on. There are many ideas to choose from, but you must focus on a specific one.

Human Biology research topics are all about us. These topics focus on different body parts, such as the human brain, the human immunological system, the nervous system, etc. In addition, you can discuss DNA modifications in humans and explain why genetic disorders occur in your research projects. Various cell research is also common today.

Biology research topics on the environment are in great demand too. For example, climate change is becoming a more significant threat every day. By studying environmental topics in biology for projects and research, we can come up with ways to combat them and preserve ecosystems.

Microbiology research topics delve into things we can’t see. There are trillions of microbes and bacteria all around us. Knowing about them is essential to understanding what makes us sick and how to fight against them. All microbiology research paper topics are pretty complicated yet very engaging to include in your paper research.

Molecular biology topics dive even deeper into the level of atoms and molecules. The various medicines and drugs we take were all created through molecular-biology research. It is one of the areas full of ideas, but there is yet to be much evidence. Science is advancing in this realm but still needs a lot of time. Topics of molecular biology will need days for research only.

Keep in mind that there are more ideas and variations of this science. We offer more examples in further sections of the article about developmental biology, marine biology, evolutionary biology, etc. Explore them and make your writing appealing and meaningful in the eyes of a professor.

How to Choose a Topic for Biology Research Paper?

When choosing a biology project topic, you must be aware of one or more fields of science. Biology research is critical to the present world. By doing research, we can learn more about genetic disorders, immune disorders, mental health, natural disease resistance, etc. Knowing about each of these could save lives in the future.

For those who may not have the time or resources to do their own research, there are research paper writing services that can provide assistance with the project. And we are always here to help you find your own topic among interesting biology research topics. Here we prepared some useful tips to follow.

• Tip 1: The level of interest matters Pay attention to one that interests you, and you might have ideas on how to develop the topic. Passion is fundamental in research, after all.
• Tip 2: Explore the topic Try to narrow things down a bit. If the topic is too broad, you may not be able to cover all aspects of it in one research paper. If it is too narrow, the paper could end up too short. Analyze the topic and the ways to approach it. By doing so, you can strike a balance between the two.
• Tip 3: Discover the recent developments To make your research paper touchable with the present day, you must explore the latest developments in the field. You can find out what kind of research has been done recently by looking at journals. Check out research papers, topics, research articles, and other sources.
• Tip 4: Ensure to get enough resources When choosing a topic, make sure it has plenty of resources available. For example, a research paper on xenobiology or cutting-edge nanobiology might sound attractive. Still, you might have difficulties getting data and resources for those unless you are a researcher at a government lab. Data, resources, complex numbers, and statistics are all invaluable to writing a paper about these topics.

That is why we have selected a range of biological topics. The topics on this list are all hopefully exciting topics for research you could write an excellent paper on. We should also add that easy biology topics to research are rare, and a writer usually needs days to prepare and start writing. Yes, biology research topics for high school students are a bit easier, but still, they need time to explore them.

On the other hand, biology research topics for college students are far more complex and detailed. Some people prefer evolutionary biology research paper topics, and we can agree with this claim. These research areas do have a lot of potential and a lot of data to support the claims. Others prefer cell biology research topics that are a bit specific and fun. Anyway, with this article’s list of easy biology research topics, you will surely find the one matching your interest.

For those who may not have the time or resources to do their own research, there are provide assistance with the project.

Top Research Biology Paper Topics

This section contains a large selection of research biology paper topics. You will be able to find one that will suit you the best. The only thing left is to decide what variation of science you prefer. Whether you’re interested in microbiology, genetics, or any other type of science, you’ll find a topic to get you started. If you’re ever stuck or need some extra help, you can always pay someone to write your paper for you. So, take a look, and choose the perfect topic for your project!

15 Developmental Biology Topics For Research

Exploring the processes of how cells grow and develop is exciting. The human body contains millions of cells, and it’s interesting to research their behavior under different conditions. If you feel like writing about it, you can find some interesting biology topics below.

• How do stem cells form different tissues?
• How are tumors formed?
• Duplication of genomes
• Plasticity of development
• Different birth defects
• Interactions between genes and the environment
• Anticancer drugs mixtures
• Developmental diseases: Origin
• Drosophila Oogenesis
• Most deadly viruses
• Most deadly bacteria in the world
• How do germs affect cells?
• How does leukemia start?
• Development of the cardiovascular system in children
• How do autoimmune diseases start and affect the human body?

15 Immune System Biology Research Topics

For decades, many scientists and immunologists have studied the human immune system and tried to explain its reaction to various pathogens. This area allows you to deepen into it and reveal how a body protects itself from harmful impact. Look over the biology research questions below and find your match-up.

• How does the human body’s immune system work?
• The human immune system: How to strengthen it?
• What makes the immunological system weaker?
• The notion of auto-immune diseases and their effect on the body’s immune system
• The global HIV/aids epidemic
• What methods are used to prevent the spread of hives?
• Living with auto-immune diseases
• Genetics and the immune system: effects and consequences
• How do immune disorders affect the body, and what causes them?
• Are allergies signs of worrying about an immune disorder?
• DNA modification in solving immune disorders
• Stress as the biggest ruiner of the immunological system
• Vaccines as strong supporters of the immunological system
• The perception of vaccines in society
• Why do some people refuse vaccines and put others around them in danger?

15 Cell Biology Research Topics

Cell study might seem challenging yet very engaging. It will be a good idea to compare various types of cells and compare them in animals and plants. Make your choice from the list of cell biology research topics below.

• The structure of an animal cell
• Mitochondria and its meaning in cell development
• Cells classification and their functions
• Red blood cells and their function in transporting oxygen
• White blood cells and their responsibility to fight diseases
• How are plant cells different from animal cells?
• What would it be if animals had a function to photosynthesize?
• Single-celled organisms: What is it, and how do they work?
• What processes do cells go through in division?
• Invasion of bacteria into the body
• Viruses – alive or not?
• Fungi: their reproduction and distribution
• Cancer cells: Why are they so dangerous?
• What methods are used to kill cancer cells?
• The role of stem cells and their potential in a body

15 DNA Research Topics

The variety of biology research topics for college students might impress you a lot. This is a science with a large field of investigation, disclosing much scientific information to use in your project. The notion of DNA and its gist are also excellent options to write about.

• The structure of the human DNA
• The main components of a DNA chain
• Why does DNA have a double-helix spiral structure?
• The purpose of chromosomes
• MRNA and its relation to DNA
• Do single-celled organisms have DNA?
• Do viruses have DNA?
• What happens if you have too many or too few chromosomes?
• Analyzing the structure of DNA using computers
• Uses for the DNA of extinct organisms like mammoths and dinosaurs
• Storing non-genetic information in DNA
• Can you write a computer program into human DNA?
• How does radiation affect DNA?
• Modifying DNA to treat aids
• Can we fight cancer through DNA modification?

15 Molecular Biology Research Topics

Do you prefer to research molecules’ chemical and physical composition? We gathered some molecular biology research topics to make your choice easier.

• The structure and components of a gene
• How do molecules move in and out of a cell?
• The basic building blocks of life
• How are drugs designed for humans?
• How is a vaccine designed to target a specific disease?
• Dominant genes vs. recessive genes
• Prion disease – why is it so dangerous?
• Hormones and their function in the body
• Developing artificial hormones from other animals
• How to carry out a western blot?
• Testing and analyzing DNA using PCR
• The three-dimensional structure of a molecule
• What is DNA transcription, and how is it used?
• The structure of a prion
• What is the central dogma of molecular biology?

15 Neurobiology Research Topics

The more you dive into science, the more exciting things you find. That’s about biology. Here, you can choose biology research topics for high school and try to reveal more simply.

• Nervous system: its structure and function
• Neurons as unique cells playing a central role in the nervous system
• What is the maximum reaction speed in a human?
• Reaction speed: how to improve it?
• Research on Organic Farming
• What are the symptoms of Alzheimer’s disease?
• Why do we feel happy or sad?
• Headaches in terms of Neurobiology
• What are the reasons for neurobiological degeneration?
• Myths and reality of Amnesia
• What causes Alzheimer’s Disease, and what are the consequences of the disease?
• What is the treatment for Spinal Cord Injury?
• Studies on Narcolepsy and Insomnia: What are the causes?
• Is there a connection between Mental Health and Neurobiology?
• Emotions in terms of their reflection in the brain

15 Abortion, Human cloning, and Genetic Researches Topics

There are so many scientific researches and theories that society accepts or neglects. You can operate different notions and try to explain them, reflecting their advantages and downsides for a human being. We gathered some enticing life science research topics for high school students that might interest you.

• The controversy around abortion: legal or not?
• Can abortion be safe?
• Human cloning – reality vs. science-fiction
• The goals of cloning humans
• Are human cloning and transplantation ethical?
• Having a “perfect child” through gene therapy: Is it a myth?
• How far has gene therapy gone in genetic research?
• Advantages and disadvantages of gene therapy
• How gene therapy can help beat cancer
• How gene therapy can eliminate diabetes
• The opportunity to edit genes by CRISPR
• DNA modifications in humans to enhance our abilities – an ethical dilemma
• Will expensive gene therapy widen the gap between the rich and the poor?
• Cloning: the good and the Bad for a Generation
• The disadvantages of cloning
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15 Environmental and Ecology Topics for Your Research

The nature around us is so enormous and includes many branches to investigate. If you are keen on the environment and how ecology affects it, the list of follow-up biology paper topics might be helpful to you.

• The theory of evolution
• How does natural selection work?
• How do living organisms adapt to their environment?
• The concept of divergent and convergent evolution
• Building a sustainable environment
• Development of environment-friendly cities
• How to control population growth?
• Why have recycling resources become so essential in the modern world?
• The effect of plastic on the environment
• What are the global consequences of deforestation?
• What can we expect when losing biodiversity?
• Ecological damage: How to prevent it?
• How can GMO products affect ecology?
• Cloning endangered or extinct species: Is it a good idea?
• Is climate change the main reason for disrupting ecology?

15 Plant Pathology Biology Research Topics

Many factors impact human health and the quality of food products matters. These easy biology research topics will be useful if you want to describe the connection between those two concepts.

• How do plants protect themselves from diseases?
• How to increase the plant’s resistance to diseases?
• Diseases distribution among plants
• The banana pandemic
• How do herbicides influence plants?
• Corn blight
• Can any plant diseases affect humans?
• The issue of stem rust and its impact on wheat
• What approaches are used to struggle against invasive plants and affected weeds?
• Fertilizers: their pros and cons on plants
• Plant disease genetics: its system and structure
• What is the connection between ecological changes and plant diseases?
• Modifications on food production because of plant diseases
• How do fungal and viral diseases appear in plants?
• The sweet potato virus

15 Animals Biology Research Topics

It’s hard to find someone who doesn’t like animals. If you are curious about animals scientifically, here you are with biology research paper topics in this field.

• Classification of animals
• Land-based life: its evolution history
• Controversies about keeping animals as pets
• Is it ethical to test drugs and products on animals?
• Why do nature reserves against zoos?
• Evidence on prehistoric aquatic animals growing giant
• What species of animals are vegan?
• Animals and their social behavior
• Primate behavior
• How intelligent can other primates be?
• Are wolves and dogs intelligent?
• Domesticating animals
• Hibernation in animals
• Why animals migrate
• Should we bring back extinct animals?

15 Marine Biology Research Topics

The marine theme is engaging as it reveals so many interesting facts about life forms dwelling under the water. You can make your paper look captivating using biology topics in marine below.

• How acidification affects aquatic environments
• Evolution in the deep sea
• What’s the meaning of camouflage mechanism in sea life?
• Consequences of oil spills on marine life
• Oldest marine species
• How do whales communicate with each other?
• How blind fish navigate
• Are marine shows and aquariums ethical?
• The biology and life cycle of seabirds
• How jellyfish are immortal
• Plankton ecology
• Difference between freshwater and seawater marine life
• Coral reefs: their importance and evolution
• Saving and restoring coral reefs
• Life in the deep-sea ocean trenches

15 Zoology Research Topics

Zoology can be an excellent choice to write about if you are close to animal studies. Look at biology topics to research and choose the one that fits your interest most.

• Asian elephants and human speech patterns
• Oyster genomes and adaptation
• Darwin’s work in the Galápagos Islands
• Asian carp: Invasive species analysis
• Giant squids: Fact vs. fiction
• Coyote and wolf hybrid species in the United States
• Parasites and disease
• Migration patterns of killer bees
• The treatment of species in Melville’s Moby Dick
• Biodiversity and plankton
• The role of camels and the development of Africa and the Middle East
• Muskellunge and adaptive creek mechanisms to small water
• Ants and cooperative behavior among species
• Animal communication and the origin of language
• Speech in African Gray Parrots

15 Genetics Research Topics

Writing about modifications caused on the gene level is pretty challenging but very fascinating. You can select one among the biological questions for research and bring up a meaningful paper.

• Genetics and its role in cancer studies
• Can genetic code be confidential?
• Is it possible to choose the sex of a person before birth?
• Genetics as a ray of hope for children with an intellectual disability
• What factors in human genetics affect behavior?
• Is it somehow possible to improve human personality through genetics?
• Are there any living cells in the gene?
• Fighting HIV with gene mutations
• Genetic mutations
• How addictive substances affect genes
• Genetic testing: is it necessary?
• Cloning: positive or negative outcome for future generations
• Pros and cons of genetic engineering
• Is the world ready for the bioethics revolution?
• The linkage between genetics and obesity

15 Biotechnology Research Topics

The way scientists conduct research today is magnificent. Implementing high-tech innovations in biology research brings new opportunities to study the world. What are these opportunities? Explore biotechnology research topics for college students and disclose the best options for you.

• Biotechnology used in plant research
• What is the contribution of biotechnology to food?
• Pharmacogenetics: What is it, and how it works?
• How are anti-cancer drugs produced to be effective?
• Nanotechnology in DNA: How to isolate it?
• Recent nanotechnology used in HIV treatment
• What biotech apps are used to detect foodborne pathogens in food systems?
• Genotypes research: Why are they tolerant and sensitive to heavy metal?
• High-tech solutions in diagnosing cancer
• Forensic DNA and its latest developments
• Metabolic changes at the level of cells
• Nanotechnology in improving treatments for respiratory viruses
• The latest biotech discoveries
• Digital evolution: bioresearch and its transformation
• The concept of vaccine development

15 Evolutionary Biology Research Topics

Knowing how life forms started their existence is fundamental. And more interesting is to look through the evolution of many processes. If you find this trend of research more engaging, we outlined evolutionary biology research paper topics to diversify your choice.

• Darwin’s concept’s impact on science
• The evolution concept by Lamarck
• Origins of the evolutionary theory
• Evolution acceptance: a belief vs. a theory?
• Evolutionary in microbiology
• Development of robotics
• Revealing differences: human brain & animal brain
• Preservation of biological resources
• Transformations in aging
• Adaptive genetic system
• Morphometrics’ history
• Developmental theory and population genomics
• Bacteria ecology’s evolution
• Biological changes: impact and evolution
• Infectious diseases and their profession

The world of science and biology is vast, making research tedious. Use our list of interesting biology research topics to choose the best issue to write your own paper.

However, it is still hard to prepare a high-quality biology research paper, even with a brilliant topic. Not all college students can do it. Do you feel like you need some help? Then buy biology paper from our professional writers! Our experts will choose the best biology experimental research topics for you and can bring up top-level papers within the shortest time. Additionally, if you need help with a statistics project related to biology, our team of experienced professionals is equipped to provide you with the utmost quality of research and analysis.

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• USC Libraries
• Research Guides
• *Biological and Life Sciences

Quantitative Biology

*biological and life sciences: quantitative biology.

• Human Biology
• Computational Biology and Bioinformatics
• Biotechnology
• Molecular Genetics and Biochemistry
• Neuroscience
• Human Development and Aging
• Health Promotion and Disease Prevention
• Human Movement Sciences
• Natural Science
• Marine Biology
• Environmental Science

These databases will help you with specific research in quantative biology:

• arXiv Started in August 1991, arXiv.org (formerly xxx.lanl.gov) is a highly-automated electronic archive and distribution server for research articles in the areas of physics, mathematics, computer science, nonlinear sciences, quantitative biology and statistics. arXiv is maintained and operated by the Cornell University Library.
• Cold Spring Harbor Laboratory Press This resource includes access to all six of their journals; their Protocols; and the Cold Spring Harbor Symposia on Quantitative Biology. This is especially strong for molecular biology topics.
• Colloquium Digital Library of Life Sciences The Colloquium Digital Library is an original collection of PDF e-books for researchers, instructors, and advanced-level students in the biomedical life sciences. Colloquium Lectures are organized by subject area, or Series including Biotechnology; Building Blocks of the Cell: Cell Structure & Function; Cell Biology of Medicine; The Developing Brain; Developmental Biology; The Genetic Basis of Human Disease; Genomic and Molecular Medicine; Integrated Systems Physiology: From Molecule to Function to Disease; Neurobiology of Alzheimer's Disease; Neuroglia in Biology and Medicine: From Physiology to Disease; Neuropeptides; Protein Activation and Cancer; Stem Cell Biology; and Quantitative Cell Biology.
• Scopus Scopus is an expertly curated database that focuses on life sciences, physical sciences, and health sciences research. Find the latest research in the field.

Here are recent ebooks that can get you started with quantative biology:

• Quantitative Biology: Dynamics of Living Systems by Akatsuki Kimura ; Jason Edward Shoemaker ; Rinshi S. Kasai ; Ziya Kalay ; Hiroaki Takagi ; Douglas B. Murray ; Chun - Biu Li ; Akira Funahashi ; Tetsuya J. Kobayashi ; Viji M. Draviam ; Noriko Hiroi ; Naoki A. Irie ISBN: 9782889452132 Publication Date: 2017 With the emergence of Systems Biology, there is a greater realization that the whole behavior of a living system may not be simply described as the sum of its elements. To represent a living system using mathematical principles, practical quantities with units are required. Quantities are not only the bridge between mathematical description and biological observations; they often stand as essential elements similar to genome information in genetics. This important realization has greatly rejuvenated research in the area of Quantitative Biology. Because of the increased need for precise quantification, a new era of technological development has opened. For example, spatio-temporal high-resolution imaging enables us to track single molecule behavior in vivo. Clever artificial control of experimental conditions and molecular structures has expanded the variety of quantities that can be directly measured. In addition, improved computational power and novel algorithms for analyzing theoretical models have made it possible to investigate complex biological phenomena. This research topic is organized on two aspects of technological advances which are the backbone of Quantitative Biology: (i) visualization of biomolecules, their dynamics and function, and (ii) generic technologies of model optimization and numeric integration. We have also included articles highlighting the need for new quantitative approaches to solve some of the long-standing cell biology questions.

Here are some of the academic journals that USC Libraries subscribes to that are related to quantative biology:

• Cold Spring Harbor Symposia on Quantitative Biology Since 1933, major discoveries in biology--such as the structure of DNA, the genetic code, the polymerase chain reaction (PCR), and RNA interference (RNAi)--have been presented and debated at the Symposium held every summer at Cold Spring Harbor Laboratory in New York. Each Symposium focuses on a different and timely area of biological research and is attended by the leading figures in the field. The speakers are handpicked luminaries and rising stars who also publish a detailed discussion of the work they present in the annual Cold Spring Harbor Symposia on Quantitative Biology volume.
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Biology Research Projects for High School Students: 20 Ideas To Try This Summer

By János Perczel

Co-founder of Polygence, PhD from MIT

16 minute read

Biology and biomedical research are two of the most popular academic disciplines among high schoolers. If you’re someone who’s interested in those fields and you’re looking for research opportunities this summer, you’ve come to the right place! With the study of biology, not only can you gain a better understanding of the natural world, but your research can have practical applications in fields like medicine, agriculture, and environmental science. Whether you’re just starting out in your exploration of biology, have taken a biology class in school, or you’re looking to do some advanced research to submit to your state’s science fair , we have level-appropriate ideas for you!

With a variety of topics like cancer treatment, genetics, neurodegenerative diseases, and marine life, we’ve got you covered. Here is a curated list of 20 different research project ideas to get those creative juices flowing. If you’re hungry for more, head over to our comprehensive Project Ideas database here and browse over 2800 more ideas!  

Research YOUR fave areas of Biology and Medicine

Polygence pairs you with an expert mentor in to create a passion project around biology and medicine. Together, you work to create a high quality research project that is uniquely your own. We also offer options to explore multiple topics, or to showcase your final product!

Human Body Project Ideas

Rate of cognitive decline in different elevations.

Oxygen partial pressure decreases with altitude, challenging blood oxygenation which may affect brain function. If you’ve ever felt some altitude sickness, then this is exactly what’s happening. This is because the atmospheric pressure decreases at higher elevations, leading to a decrease in the partial pressures of the gasses in the air, including oxygen. And of course, oxygen is needed for us to function. What is the effect on brain health/ cognition in sudden increased elevation: say, climbing Mount Everest? Does chronic exposure to high elevations increase the likelihood of dementia? In this project, a meta-analysis of published works examining the effects of altitude on cognition would be conducted.

Idea by mentor Alyssa

Building a Blood Vessel

Use online graphics to illustrate how a blood vessel forms. Blood vessels are structures that carry blood and are responsible for transporting nutrients and oxygen throughout the body. There are three main types of blood vessels: arteries, veins, and capillaries. For this project, complete a literature search to understand what is known about blood vessel growth. Then, utilize this information to generate a graphic with no words to demonstrate how the vasculature (network of blood vessels) forms. The goal of this project is to explain science without using text and therefore make it more available to a larger community.

Idea by mentor Natalie

Examining the bacterial profile of various households

As of late, bacterial microbiomes have been a huge and interesting topic in the field of bacteriology as they play an important role in human health. Bacterial microbiomes are communities of bacteria that live on or outside organisms. They’re found in various parts of the human body, and help us to digest food and regulate our immune system. In this project, you will seek to understand how skin microbiomes can differ between different  individuals of different households. This project will require making different bacterial media that can be made at home selecting for various microorganisms. If you’re new to preparing bacterial media, check out this resource here!

Idea by mentor Hamilton

Regulation of Circadian Clocks

Sleep is known to be governed by two distinct processes: a circadian clock that aligns sleep and wakefulness to the solar day and the sleep homeostat that encodes for sleep debt as a compensatory mechanism against sleep loss. You’ve most likely heard about circadian rhythm and our body’s internal clock, and circadian regulation of sleep is a fundamental process that allows animals to anticipate sleepiness or wakefulness consistently every day. These mechanisms can be regulated in multiple ways: at the gene, protein, gene, and clock neuronal level. In this project, we will focus on 1) how to efficiently digest primary and review articles to compile and condense information, 2) investigate how circadian clocks are regulated at these different genetic levels, and 3) try to effectively summarize the information we've gathered. We can present this information in a variety of ways, and what the final product looks like is up to you.

Idea by mentor Oscar

The Biology of Aging

Aging is the number one risk factor for a variety of diseases including cancer, neurodegenerative disease, and loss of hearing/sight. We are only now beginning to truly understand the process of aging and have even started to uncover ways that we could stop, or potentially reverse, the effects of aging. What are the hallmarks/signs of aging? How do researchers study 'aging'? How does human lifespan and aging compare to the rest of the animal kingdom? Is it possible to stop or reverse the effects of aging? What advancements are being made related to this? We could explore these questions or brainstorm others you might have about the biology of aging.

Idea by mentor Emily

Animals, Plants, and Nature Project Ideas

How genetically engineered mosquitoes are reducing rates of vector-borne diseases such as zika.

Many countries are already releasing millions of genetically engineered mosquitoes into the wild every week. These mosquitoes have been modified to reduce their ability to transmit disease-causing pathogens like dengue fever, Zika, and malaria, and are sent into the wild to mate with disease-carrying mosquitoes. However, this is still controversial as some people are concerned about the unintended consequences on the environment. What could be the potential pros and cons for this? The project will mainly focus on doing meta analysis of articles and watching informative videos to understand how/why genetically engineered mosquitoes can be used to reduce rates of different diseases. Students will have the chance to use critical thinking and do in-depth research on genetic engineering techniques, how scientists determine breeding rates and number of insects released, and epidemiology of different bloodborne diseases.

Idea by mentor Vanessa

Efficacy of Marine Protected Areas

Marine protected areas (MPAs) are areas of ocean or coastal waters that are set aside for the conservation and sustainable use of marine resources. These areas are established by governments, NGOs, or other organizations, and they can take different forms, from fully protected "no-take" zones to areas with regulated fishing or other activities. Marine protected areas have the potential to guide sustainable resource management and protect biodiversity, but have a host of reasons for why they are not currently effective. Explore reasons for why MPAs may not be effective. Then develop a framework for mapping, modeling, and implementing an effective Marine Protected Area.

Bioinspiration: Do animals hold the answers?

Can the toxins produced by frogs help us fight antibiotic resistant bacteria strains? How can understanding how lizards and newts regrow their limbs help us improve wound treatment? Why do tilapia skins help with burns? Discover the role of animals in the development of modern medicine as well as its potential. Are there any ethical concerns with these developments and findings? If so, what are they and do they matter? Share your findings in a research proposal, article, or presentation.

Idea by mentor Cheyenne

How Climate Change Can Affect Future Distributions of Rare Species

Climate change, such as global warming and longer drought, can threaten the existence of some of the rarest plants on earth. It is important to understand how future suitable habitats will change for these rare species so that we can target our conservation efforts in specific areas. In this project, you will identify a rare species that you like (it can be animals, plants, or fungi!), and gather the data online on its current occurrences. Then you will learn how to perform species distribution modeling to map its current and future suitable habitat areas. To get you started on learning species distribution modeling, check out this Youtube resource here. The changes in the amount or location of future suitable habitats can significantly affect the destiny of a rare species. By doing this project, you will not only learn skills in data analyses but also become the best ambassador for this rare species that you love. 

Idea by mentor Yingtong

A Reef’s Best Frenemies

Coral reefs are in global decline. A primary cause of this is "coral bleaching" which results in the white reefs we often see in the news. Coral bleaching is actually the breakdown in the partnership between the coral animal and tiny, symbiotic algae that live within its cells. Corals and algae have a variety of thermal tolerances which are likely decided by genetic and environmental factors. However, despite how important this relationship is, it's currently very poorly understood. This project would review existing literature on the symbiotic partnernship and try to identify factors that predict bleaching and thermal resilience.

Idea by mentor Carly

Dive in to BioMed NOW!

Register to get paired with one of our expert mentors and to get started on exploring your passions today! You have agency in setting up your schedule for this research. Dive in now!

Diseases and Treatments Project Ideas

The understanding of a new and upcoming treatment: immunotherapy.

Immunotherapies have been growing in the past few years as alternative treatments for many types of cancer. These treatments work by boosting the patient's immune system to fight the disease, however it is not always effective. There are many types of immunotherapies with various nuances, but they all work to attack specific cells that are causing the disease. For this project, pick one of a few types of immunotherapy and deeply understand the mechanism of action and what is the current effectiveness against the cancer it treats.

Idea by mentor Hannah

Exploring The Cancer Genome Atlas data 

There has been an explosion of publicly available data for cancer. The Cancer Genome Atlas was a research program with the purpose of creating a comprehensive catalog of genomic and molecular information about different types of cancer, with the aim of improving our understanding of the disease and developing new treatments. The dataset has been used to identify new cancer subtypes, develop diagnostic tests, and discover potential targets for new cancer therapies. Explore the implications and impact of The Cancer Genome Atlas data, and why it’s become so important.

Idea by mentor Hersh

Systematic Review and Meta-Analysis of Physiological Benefits of Fasting-induced Autophagy

Autophagy, meaning "self-eating", is a cellular process where damaged or unwanted components are disposed. Autophagy has been linked to various diseased pathologies, including cancer and heart disease. Fasting or specific dietary lifestyles may induce levels of autophagy in the human body. In this project, we will perform and systematic review and meta-analysis of fasting or diet-induced autophagy and its benefits on the body. You will gain skills in 1) searching and reviewing primary literature, 2) computational skills for performing data analysis (R language), and 3) writing your scientific findings.

Idea by mentor Jose 

The Amyloid Hypothesis: Sifting through the controversy

For many years, scientists have thought that amyloid beta was the protein responsible for a patient developing Alzheimer's Disease symptoms. This "Amyloid Hypothesis" is now being questioned in light of current clinical data. Recently, drugs have been developed that reduce amyloid beta in patients. Surprisingly, the drugs worked in reducing amyloid beta, but it did not result in the slowing of disease pathology. Does this mean that the amyloid hypothesis is incorrect? Is amyloid beta less important in the progression of disease then what we once thought? This research project aims to explore the issues with the amyloid hypothesis and to assess where we stand in our understanding of amyloid beta's contribution to Alzheimer’s.

Idea by mentor Patrick

How do vaccines work?

During the COVID pandemic, vaccines have been all over the news! But how do they actually work? What’s the science behind them? Through this project, you will explore how vaccines work and the history of science behind vaccine development. While the final product of the projectwill be up to you, the ultimate goal of this project is for you to be a true public health advocate for vaccines and to be able to communicate why vaccines are so important in a way that the general public can understand.

Idea by mentor Helen

Sleep Disruption Profiles in Various Mouse Models of Alzheimer’s

Alzheimer's disease (AD) has been studied for decades but we are no closer to understanding the mechanisms of the disease. Because of the vast number of researchers studying AD, there are numerous models used to study the disease. All these models have different sleep profiles, phenotypes, disease onsets, sex differences etc. Therefore, in this project we will compile a document based on extensive literature review about the various models there are. We will focus on sleep profiles in these animals with an emphasis on male and female differences. This information is valuable because it is important to know which model is best to use to answer your scientific questions and there is a lot of criticism (by other scientists) that can be brought on by the model chosen so you need to be able to justify your choice. This project will also introduce you to the world of AD research and some of the gaps in knowledge in the field.

Idea by mentor Shenee

Rethinking The Treatment Of Neurodegenerative Diseases

Neurodegenerative diseases affect millions of people worldwide. They are conditions that affect the nervous system, particularly the brain and spinal cord, and examples include Alzheimer’s and Parkinson’s. While billions of dollars have been spent trying to find treatments for the disease, very few drugs and therapies have had a meaningful impact on slowing down disease progression. This is often because by the time someone is diagnosed with a disease, it has progressed too far for a treatment to have a substantial effect. Some recent approaches to treatment have turned to looking for early indications of the disease (termed "biomarkers") that can occur before the onset of symptoms. By diagnosing disease and beginning treatment before symptoms arise, these treatments could have a more profound effect in slowing down the progression of disease. Students could review the recent progress being made on identifying biomarkers for neurodegenerative diseases, and either write a paper or even record a podcast on their findings!

Idea by mentor David

Genetics Project Ideas

Height and genetics: nature or nurture.

How much do your genes determine your height? How much do nutrition and environmental factors play a role? What gene variants are implicated in height differences and what is the role of epigenetics? Epigenetics is the study of heritable changes in gene expression or cellular phenotype that occur without changes to the underlying DNA sequence. These changes can be influenced by diet and lifestyle. We will access and analyze an open dataset on twins to estimate the correlation between monozygotic twins (who have the exact same DNA) and height. You will learn to use R to open a dataset, analyze data with statistical methods such the student’s t-test, and display your data as graphs and charts. Finally, you will learn how to make a research presentation on height and genetics, describe the research methods, and present the data in a compelling and thorough way.

Idea by mentor Adeoluwa

The World of Personalized Medicine

Similar to our fingerprints, our genetic code is also unique to each individual person. Our genetic code is what determines our hair color, height, eye color, skin tone...just about everything! For those that develop diseases such as cancer, their genetic code found inside the malignant cells that comprise a tumor may also be unique to them or to certain groups of people with similar mutations (the drivers of disease). So why is it that we treat each person the same way even though the genetic drivers of that disease may be disparate? The world of Personalized Medicine is new and exciting and looks to circumvent this problem. Personalized Medicine (also known as precision medicine) uses the genetic code of a patients disease to guide treatment options that prove to be highly efficacious. Together, lets write a review on a disease of your choice that could benefit from Personalized Medicine based on current literature and research.

Idea by mentor Somer

General Biology Project Ideas

Teach a biology concept two ways: to your fellow students and to the general public.

One of the best ways to learn is to teach. Choose a biological concept that interests you and prepare a lesson and or demo on it. The format should be a video recording of yourself teaching (a la Khan Academy or a Zoom class), but the other details are up to you. Consider incorporating a demonstration (e.g. how can you use items from your kitchen to illustrate properties of mixtures?) or animation (e.g. to illustrate molecular motion). Also consider how you will check that your students understand the concept(s) and/or skill(s) you have taught them. Prepare and record two versions of your lesson: one intended for your peers and one for the general public. How will the versions differ to reflect these different audiences? You will learn what it's like to teach, gain a much greater understanding of your chosen concept(s)/skill(s), and learn how to communicate science to different audiences.

Idea by mentor Alexa

Once you’ve picked a project idea, check out some of our resources to help you progress with your project! Whether you’re stuck on how to cite sources , how to come up with a great thesis statement , or how to showcase your work once it’s finished , we’ve created blog posts to help you out. If you’re interested in doing one of the biology research projects with the help of an amazing mentor at Polygence, apply now ! If you would like some help with coming up with your own idea, book a complimentary consultation call with our admissions team here ! For more biology and science research information, check out our comprehensive list of research opportunities for high school students .

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Environmental Changes Are Fueling Human, Animal and Plant Diseases, Study Finds

Biodiversity loss, global warming, pollution and the spread of invasive species are making infectious diseases more dangerous to organisms around the world.

By Emily Anthes

Several large-scale, human-driven changes to the planet — including climate change, the loss of biodiversity and the spread of invasive species — are making infectious diseases more dangerous to people, animals and plants, according to a new study.

Scientists have documented these effects before in more targeted studies that have focused on specific diseases and ecosystems. For instance, they have found that a warming climate may be helping malaria expand in Africa and that a decline in wildlife diversity may be boosting Lyme disease cases in North America.

But the new research, a meta-analysis of nearly 1,000 previous studies, suggests that these patterns are relatively consistent around the globe and across the tree of life.

“It’s a big step forward in the science,” said Colin Carlson, a biologist at Georgetown University, who was not an author of the new analysis. “This paper is one of the strongest pieces of evidence that I think has been published that shows how important it is health systems start getting ready to exist in a world with climate change, with biodiversity loss.”

In what is likely to come as a more surprising finding, the researchers also found that urbanization decreased the risk of infectious disease.

The new analysis, which was published in Nature on Wednesday, focused on five “global change drivers” that are altering ecosystems across the planet: biodiversity change, climate change, chemical pollution, the introduction of nonnative species and habitat loss or change.

The researchers compiled data from scientific papers that examined how at least one of these factors affected various infectious-disease outcomes, such as severity or prevalence. The final data set included nearly 3,000 observations on disease risks for humans, animals and plants on every continent except for Antarctica.

The researchers found that, across the board, four of the five trends they studied — biodiversity change, the introduction of new species, climate change and chemical pollution — tended to increase disease risk.

“It means that we’re likely picking up general biological patterns,” said Jason Rohr, an infectious disease ecologist at the University of Notre Dame and senior author of the study. “It suggests that there are similar sorts of mechanisms and processes that are likely occurring in plants, animals and humans.”

The loss of biodiversity played an especially large role in driving up disease risk, the researchers found. Many scientists have posited that biodiversity can protect against disease through a phenomenon known as the dilution effect.

The theory holds that parasites and pathogens, which rely on having abundant hosts in order to survive, will evolve to favor species that are common, rather than those that are rare, Dr. Rohr said. And as biodiversity declines, rare species tend to disappear first. “That means that the species that remain are the competent ones, the ones that are really good at transmitting disease,” he said.

Lyme disease is one oft-cited example. White-footed mice, which are the primary reservoir for the disease, have become more dominant on the landscape, as other rarer mammals have disappeared, Dr. Rohr said. That shift may partly explain why Lyme disease rates have risen in the United States. (The extent to which the dilution effect contributes to Lyme disease risk has been the subject of debate, and other factors, including climate change, are likely to be at play as well.)

Other environmental changes could amplify disease risks in a wide variety of ways. For instance, introduced species can bring new pathogens with them, and chemical pollution can stress organisms’ immune systems. Climate change can alter animal movements and habitats, bringing new species into contact and allowing them to swap pathogens .

Notably, the fifth global environmental change that the researchers studied — habitat loss or change — appeared to reduce disease risk. At first glance, the findings might appear to be at odds with previous studies, which have shown that deforestation can increase the risk of diseases ranging from malaria to Ebola. But the overall trend toward reduced risk was driven by one specific type of habitat change: increasing urbanization.

The reason may be that urban areas often have better sanitation and public health infrastructure than rural ones — or simply because there are fewer plants and animals to serve as disease hosts in urban areas. The lack of plant and animal life is “not a good thing,” Dr. Carlson said. “And it also doesn’t mean that the animals that are in the cities are healthier.”

And the new study does not negate the idea that forest loss can fuel disease; instead, deforestation increases risk in some circumstances and reduces it in others, Dr. Rohr said.

Indeed, although this kind of meta-analysis is valuable for revealing broad patterns, it can obscure some of the nuances and exceptions that are important for managing specific diseases and ecosystems, Dr. Carlson noted.

Moreover, most of the studies included in the analysis examined just a single global change drive. But, in the real world, organisms are contending with many of these stressors simultaneously. “The next step is to better understand the connections among them,” Dr. Rohr said.

Emily Anthes is a science reporter, writing primarily about animal health and science. She also covered the coronavirus pandemic. More about Emily Anthes

Explore the Animal Kingdom

A selection of quirky, intriguing and surprising discoveries about animal life..

Scientists say they have found an “alphabet” in the songs of sperm whales , raising the possibility that the animals are communicating in a complex language.

Indigenous rangers in Australia’s Western Desert got a rare close-up with the northern marsupial mole , which is tiny, light-colored and blind, and almost never comes to the surface.

For the first time, scientists observed a primate in the wild treating a wound  with a plant that has medicinal properties.

A new study resets the timing for the emergence of bioluminescence back to millions  of years earlier than previously thought.

Scientists are making computer models to better understand how cicadas  emerge collectively after more than a decade underground .