good science questions to research

Research Question Examples 🧑🏻‍🏫

25+ Practical Examples & Ideas To Help You Get Started 

By: Derek Jansen (MBA) | October 2023

A well-crafted research question (or set of questions) sets the stage for a robust study and meaningful insights.  But, if you’re new to research, it’s not always clear what exactly constitutes a good research question. In this post, we’ll provide you with clear examples of quality research questions across various disciplines, so that you can approach your research project with confidence!

Research Question Examples

• Psychology research questions
• Business research questions
• Education research questions
• Healthcare research questions
• Computer science research questions

Examples: Psychology

Let’s start by looking at some examples of research questions that you might encounter within the discipline of psychology.

How does sleep quality affect academic performance in university students?

This question is specific to a population (university students) and looks at a direct relationship between sleep and academic performance, both of which are quantifiable and measurable variables.

What factors contribute to the onset of anxiety disorders in adolescents?

The question narrows down the age group and focuses on identifying multiple contributing factors. There are various ways in which it could be approached from a methodological standpoint, including both qualitatively and quantitatively.

Do mindfulness techniques improve emotional well-being?

This is a focused research question aiming to evaluate the effectiveness of a specific intervention.

How does early childhood trauma impact adult relationships?

This research question targets a clear cause-and-effect relationship over a long timescale, making it focused but comprehensive.

Is there a correlation between screen time and depression in teenagers?

This research question focuses on an in-demand current issue and a specific demographic, allowing for a focused investigation. The key variables are clearly stated within the question and can be measured and analysed (i.e., high feasibility).

Examples: Business/Management

Next, let’s look at some examples of well-articulated research questions within the business and management realm.

How do leadership styles impact employee retention?

This is an example of a strong research question because it directly looks at the effect of one variable (leadership styles) on another (employee retention), allowing from a strongly aligned methodological approach.

What role does corporate social responsibility play in consumer choice?

Current and precise, this research question can reveal how social concerns are influencing buying behaviour by way of a qualitative exploration.

Does remote work increase or decrease productivity in tech companies?

Focused on a particular industry and a hot topic, this research question could yield timely, actionable insights that would have high practical value in the real world.

How do economic downturns affect small businesses in the homebuilding industry?

Vital for policy-making, this highly specific research question aims to uncover the challenges faced by small businesses within a certain industry.

Which employee benefits have the greatest impact on job satisfaction?

By being straightforward and specific, answering this research question could provide tangible insights to employers.

Examples: Education

Next, let’s look at some potential research questions within the education, training and development domain.

How does class size affect students’ academic performance in primary schools?

This example research question targets two clearly defined variables, which can be measured and analysed relatively easily.

Do online courses result in better retention of material than traditional courses?

Timely, specific and focused, answering this research question can help inform educational policy and personal choices about learning formats.

What impact do US public school lunches have on student health?

Targeting a specific, well-defined context, the research could lead to direct changes in public health policies.

To what degree does parental involvement improve academic outcomes in secondary education in the Midwest?

This research question focuses on a specific context (secondary education in the Midwest) and has clearly defined constructs.

What are the negative effects of standardised tests on student learning within Oklahoma primary schools?

This research question has a clear focus (negative outcomes) and is narrowed into a very specific context.

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Examples: Healthcare

Shifting to a different field, let’s look at some examples of research questions within the healthcare space.

What are the most effective treatments for chronic back pain amongst UK senior males?

Specific and solution-oriented, this research question focuses on clear variables and a well-defined context (senior males within the UK).

How do different healthcare policies affect patient satisfaction in public hospitals in South Africa?

This question is has clearly defined variables and is narrowly focused in terms of context.

Which factors contribute to obesity rates in urban areas within California?

This question is focused yet broad, aiming to reveal several contributing factors for targeted interventions.

Does telemedicine provide the same perceived quality of care as in-person visits for diabetes patients?

Ideal for a qualitative study, this research question explores a single construct (perceived quality of care) within a well-defined sample (diabetes patients).

Which lifestyle factors have the greatest affect on the risk of heart disease?

This research question aims to uncover modifiable factors, offering preventive health recommendations.

Examples: Computer Science

Last but certainly not least, let’s look at a few examples of research questions within the computer science world.

What are the perceived risks of cloud-based storage systems?

Highly relevant in our digital age, this research question would align well with a qualitative interview approach to better understand what users feel the key risks of cloud storage are.

Which factors affect the energy efficiency of data centres in Ohio?

With a clear focus, this research question lays a firm foundation for a quantitative study.

How do TikTok algorithms impact user behaviour amongst new graduates?

While this research question is more open-ended, it could form the basis for a qualitative investigation.

What are the perceived risk and benefits of open-source software software within the web design industry?

Practical and straightforward, the results could guide both developers and end-users in their choices.

Remember, these are just examples…

In this post, we’ve tried to provide a wide range of research question examples to help you get a feel for what research questions look like in practice. That said, it’s important to remember that these are just examples and don’t necessarily equate to good research topics . If you’re still trying to find a topic, check out our topic megalist for inspiration.

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20 Big Scientific Questions to Get You Thinking

Updated: December 7, 2023

Published: July 25, 2021

Humans have been trying to make sense of the universe forever, and questions are a crucial part of scientific discoveries. Good scientific questions allow scientists, physicists, astronomers, and even philosophers discover more about the world around us and the intricate workings of the universe.

In this article, we’ll go over twenty of the major questions in science, in order to see how far we’ve come in understanding the universe and what remains to be discovered. Then, we’ll take a look at some scientific method questions and the anatomy of a good scientific question.

20 Big Questions in Science

1. what is the universe made of.

Astronomers still cannot account for 95% of the universe. Atoms, which were discovered to make up the world around us, is apparently only 5% of the universe’s makeup. In recent years, astronomers have postulated that a big portion of the remaining 95% may be a sort of dark matter or energy, but the question still remains to be answered.

2. How did life begin?

In anthropology it’s clear that this is a universal question that each culture and religion has tried to answer. Scientists show that life began with simple chemicals that came together and became the first replicating molecules. However, scientists are still arguing about how these first chemicals arranged themselves, or how DNA was formed, etc. Scientists also argue about the circumstances of these first chemicals, with some believing that they originated in hot pools, while others believe it began with meteorites colliding with water.

3. Are we alone in the universe?

Astronomers have been searching the universe for signs of other life as well as habitable planets. Astronomers have created radio telescopes which pick up messages from other planets, as well as scan atmospheres of other planets to detect habitable conditions which might be home to other lifeforms. The scans have revealed a whopping 60 billion habitable planets in the Milky Way.

4. What makes us human?

Scientists (and philosophers, for that matter) have been trying to discover what makes us uniquely human and distinguishable from animals. DNA itself shows little differentiation between humans and apes. The human genome is 99% identical to a chimpanzee’s, for example, and 50% identical to various vegetation. Humans have been thought to be different based on intelligence, language, and the utilization of tools, but all these theories have been disproved by studying animals who show the same traits. Some scientists believe the brains of humans were enlarged by the unique use of fire and cooking; others believe that humans have a unique ability for cooperation and skill-trading which allows us to create civilizations.

5. What is consciousness?

We are not sure what consciousness is, where it is located in the brain, or why we are conscious. Scientists agree that consciousness is made up of a network of brain regions as opposed to one particular part, but other than that, the question of consciousness is still puzzling for both scientists and philosophers.

6. Why do we dream?

The question of sleep and dreams have been an intriguing topic for scientists and psychologists alike. The famous Sigmund Freud believed that dreams expressed unfulfilled desires, while others believe that dreams are merely random firings of the brain. Recent studies on animals, using brain imaging technology, have showcased that sleep and dreams play a significant role in memory, learning, and emotions.

7. Why is there stuff?

This “stuff” is called matter, and the more scientists discover about matter and its counterpart, antimatter, the more puzzling it seems that anything exists. When matter and antimatter meet, they both disappear, so it seems that the universe has a bias toward matter existing.

 8. Are there other universes?

Cosmology and quantum physics are leaning toward the possibility of other universes and realities. The universe seems so fine-tuned that it would take an infinite amount of possibilities to end up in this particular universe.

9. Where do we put all the carbon?

In the last couple hundred years, humans have been releasing a lot of carbon dioxide into the atmosphere through burning fossil fuels. A major question now is how to maintain the earth’s equilibrium or store the carbon away to prevent further damage.

10. How do we get more energy from the sun?

With the attempt to lessen the use of fossil fuels, as well as the issue of dwindling resources, scientists are searching for alternative energy sources. The sun provides solar power, and we are also attempting to use sunlight’s energy to split water into hydrogen and oxygen in order to fuel cars in a cleaner way.

11. What’s so weird about prime numbers?

Those prime numbers that seemed useless in math class are actually the building blocks to the internet and the public key encryption which uses prime numbers to protect and lock sensitive information online. Some of the brightest minds in mathematics are still scratching their heads over the mystery of prime numbers and the patterns within them.

12. How do we beat bacteria?

Antibiotics, one of the greatest achievements of modern medicine, have helped beat some of the deadliest diseases as well as make surgery and chemotherapy possible. However, overmedication and misuse of antibiotics have led to antibiotic-resistant bacteria. Scientists are looking for new ways to prevent disease and searching for new bacteria in the oceans.

13. Can computers keep getting faster?

A typical smartphone contains more computing power than ever before. Now, some are wondering if our advanced technology can be further increased. Some suggestions to doing so include atomically thin carbon, called graphene, or new systems such as quantum computing.

14. Will we ever cure cancer?

Though we are getting better at cancer prevention and treatment, the end-all cure to cancer may never be possible. However, half of all cancers are preventable with simple, yet significant changes in lifestyle and health; such as avoiding smoking, alcohol, and prolonged exposure to harsh sun, as well as maintaining a healthy diet and exercise.

15. When can I have a robot butler?

Modern robotics may be more advanced than most people realize. Robotics are already responsible for sending out shipments, milking cows, creating most products, sorting emails, and lots more. The question of artificial intelligence, however, is a trickier topic. Though we may trust robotics to take care of many manual and technological tasks, we are not yet sure whether we would want artificial intelligence in the realm of human roles, such as Japan’s plan to have robots care for the elderly.

16. What’s at the bottom of the ocean?

It’s incredible that 95% of the ocean is completely unexplored. In 1960, sea explorers went seven miles deep — the farthest ever ventured — and the discoveries so far have included some bizarre fish, as well a possible cure for Alzheimer’s disease from crustaceans.

17. What’s at the bottom of a black hole?

According to Einstein’s theory of relativity, a black hole is created when a dying star cave in, creating a small point called a singularity. Quantum physics, on the other hand, has a completely different theory. Over decades, scientists have tried and failed to unify the two theories. Recently, a new idea called M-theory has become the leading candidate.

18. Can we live forever?

Ageing has always been a fact of life, but recently, scientists are becoming more equipped — through DNA and the genes that regulate reproductive health and metabolism — to study ageing and suggest treatments and drugs to prolong life. However, the question is not whether humans can live forever, but how we can improve health into old age.

19. How do we solve the population problem?

Since the 1960’s the population has almost doubled to 7 billion people, with an estimate of growth to 9 billion by the year 2050. With the rise in population, questions about housing, food, and fuel become crucial. In order to have enough resources and land for all these people, some are debating solutions like inhabiting other planets, building underground, and creating lab-grown meat.

20. Is time travel possible?

Though this may seem like an impossible concept only seen in sci-fi movies, time travel may in fact be possible one day. Einstein’s theory of special relativity has made it possible for astronauts orbiting on the international space station to experience time at a slower rate. Though the effect is limited, this theory may make it possible to travel many years into the future. Wormholes and spaceships may have a hand in physicist’s blueprint to traveling back in time.

Tips For Asking Good Scientific Questions

A crucial factor in doing good research is learning how to ask good scientific questions. By definition, scientific discoveries are proven through observation and evidence. In order to know where to look, scientists need to know exactly what they’re looking for, and how to word their questions in a way that will lead their scientific research.

Below is a step-by-step process to ask an effective scientific question:

Begin by asking several questions

Ask a few questions that interest you on a topic. For example, if you want to know more about how your garden produces vegetables and plants, you may begin by asking several questions, such as how seeds grow, how plants absorb nutrients, and more.

Eliminate questions

Now that you have a general direction, eliminate any questions that cannot be scientifically proven through observation. This cuts out any questions which are based on opinion, beliefs, or values.

Break down broad questions

Take your remaining questions and break them down into more specific questions. Following our garden question, you might ask, “how do various factors affect seed germination?” or “what factors are necessary for the seed germination of a garden tomato?”

Word questions for experiments

Now that you know what you want to research, word your question in order to prepare it for experimentation. Some experiment-based questions may begin with, “what is the relationship between ___ and ___?” or “what is the effect of ___ on ___?”

These big scientific questions are the foundation of all the major scientific discoveries.

With so much in the universe yet to be discovered, it’s fascinating to see how far scientists have come, and how far we still want to go in uncovering the mysteries of the universe. All these discoveries started with a scientific question, and a good scientific method for asking questions is crucial for understanding the world around us.

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A Practical Guide to Writing Quantitative and Qualitative Research Questions and Hypotheses in Scholarly Articles

Edward barroga.

1 Department of General Education, Graduate School of Nursing Science, St. Luke’s International University, Tokyo, Japan.

Glafera Janet Matanguihan

2 Department of Biological Sciences, Messiah University, Mechanicsburg, PA, USA.

The development of research questions and the subsequent hypotheses are prerequisites to defining the main research purpose and specific objectives of a study. Consequently, these objectives determine the study design and research outcome. The development of research questions is a process based on knowledge of current trends, cutting-edge studies, and technological advances in the research field. Excellent research questions are focused and require a comprehensive literature search and in-depth understanding of the problem being investigated. Initially, research questions may be written as descriptive questions which could be developed into inferential questions. These questions must be specific and concise to provide a clear foundation for developing hypotheses. Hypotheses are more formal predictions about the research outcomes. These specify the possible results that may or may not be expected regarding the relationship between groups. Thus, research questions and hypotheses clarify the main purpose and specific objectives of the study, which in turn dictate the design of the study, its direction, and outcome. Studies developed from good research questions and hypotheses will have trustworthy outcomes with wide-ranging social and health implications.

INTRODUCTION

Scientific research is usually initiated by posing evidenced-based research questions which are then explicitly restated as hypotheses. 1 , 2 The hypotheses provide directions to guide the study, solutions, explanations, and expected results. 3 , 4 Both research questions and hypotheses are essentially formulated based on conventional theories and real-world processes, which allow the inception of novel studies and the ethical testing of ideas. 5 , 6

It is crucial to have knowledge of both quantitative and qualitative research 2 as both types of research involve writing research questions and hypotheses. 7 However, these crucial elements of research are sometimes overlooked; if not overlooked, then framed without the forethought and meticulous attention it needs. Planning and careful consideration are needed when developing quantitative or qualitative research, particularly when conceptualizing research questions and hypotheses. 4

There is a continuing need to support researchers in the creation of innovative research questions and hypotheses, as well as for journal articles that carefully review these elements. 1 When research questions and hypotheses are not carefully thought of, unethical studies and poor outcomes usually ensue. Carefully formulated research questions and hypotheses define well-founded objectives, which in turn determine the appropriate design, course, and outcome of the study. This article then aims to discuss in detail the various aspects of crafting research questions and hypotheses, with the goal of guiding researchers as they develop their own. Examples from the authors and peer-reviewed scientific articles in the healthcare field are provided to illustrate key points.

DEFINITIONS AND RELATIONSHIP OF RESEARCH QUESTIONS AND HYPOTHESES

A research question is what a study aims to answer after data analysis and interpretation. The answer is written in length in the discussion section of the paper. Thus, the research question gives a preview of the different parts and variables of the study meant to address the problem posed in the research question. 1 An excellent research question clarifies the research writing while facilitating understanding of the research topic, objective, scope, and limitations of the study. 5

On the other hand, a research hypothesis is an educated statement of an expected outcome. This statement is based on background research and current knowledge. 8 , 9 The research hypothesis makes a specific prediction about a new phenomenon 10 or a formal statement on the expected relationship between an independent variable and a dependent variable. 3 , 11 It provides a tentative answer to the research question to be tested or explored. 4

Hypotheses employ reasoning to predict a theory-based outcome. 10 These can also be developed from theories by focusing on components of theories that have not yet been observed. 10 The validity of hypotheses is often based on the testability of the prediction made in a reproducible experiment. 8

Conversely, hypotheses can also be rephrased as research questions. Several hypotheses based on existing theories and knowledge may be needed to answer a research question. Developing ethical research questions and hypotheses creates a research design that has logical relationships among variables. These relationships serve as a solid foundation for the conduct of the study. 4 , 11 Haphazardly constructed research questions can result in poorly formulated hypotheses and improper study designs, leading to unreliable results. Thus, the formulations of relevant research questions and verifiable hypotheses are crucial when beginning research. 12

CHARACTERISTICS OF GOOD RESEARCH QUESTIONS AND HYPOTHESES

Excellent research questions are specific and focused. These integrate collective data and observations to confirm or refute the subsequent hypotheses. Well-constructed hypotheses are based on previous reports and verify the research context. These are realistic, in-depth, sufficiently complex, and reproducible. More importantly, these hypotheses can be addressed and tested. 13

There are several characteristics of well-developed hypotheses. Good hypotheses are 1) empirically testable 7 , 10 , 11 , 13 ; 2) backed by preliminary evidence 9 ; 3) testable by ethical research 7 , 9 ; 4) based on original ideas 9 ; 5) have evidenced-based logical reasoning 10 ; and 6) can be predicted. 11 Good hypotheses can infer ethical and positive implications, indicating the presence of a relationship or effect relevant to the research theme. 7 , 11 These are initially developed from a general theory and branch into specific hypotheses by deductive reasoning. In the absence of a theory to base the hypotheses, inductive reasoning based on specific observations or findings form more general hypotheses. 10

TYPES OF RESEARCH QUESTIONS AND HYPOTHESES

Research questions and hypotheses are developed according to the type of research, which can be broadly classified into quantitative and qualitative research. We provide a summary of the types of research questions and hypotheses under quantitative and qualitative research categories in Table 1 .

Research questions in quantitative research

In quantitative research, research questions inquire about the relationships among variables being investigated and are usually framed at the start of the study. These are precise and typically linked to the subject population, dependent and independent variables, and research design. 1 Research questions may also attempt to describe the behavior of a population in relation to one or more variables, or describe the characteristics of variables to be measured ( descriptive research questions ). 1 , 5 , 14 These questions may also aim to discover differences between groups within the context of an outcome variable ( comparative research questions ), 1 , 5 , 14 or elucidate trends and interactions among variables ( relationship research questions ). 1 , 5 We provide examples of descriptive, comparative, and relationship research questions in quantitative research in Table 2 .

Hypotheses in quantitative research

In quantitative research, hypotheses predict the expected relationships among variables. 15 Relationships among variables that can be predicted include 1) between a single dependent variable and a single independent variable ( simple hypothesis ) or 2) between two or more independent and dependent variables ( complex hypothesis ). 4 , 11 Hypotheses may also specify the expected direction to be followed and imply an intellectual commitment to a particular outcome ( directional hypothesis ) 4 . On the other hand, hypotheses may not predict the exact direction and are used in the absence of a theory, or when findings contradict previous studies ( non-directional hypothesis ). 4 In addition, hypotheses can 1) define interdependency between variables ( associative hypothesis ), 4 2) propose an effect on the dependent variable from manipulation of the independent variable ( causal hypothesis ), 4 3) state a negative relationship between two variables ( null hypothesis ), 4 , 11 , 15 4) replace the working hypothesis if rejected ( alternative hypothesis ), 15 explain the relationship of phenomena to possibly generate a theory ( working hypothesis ), 11 5) involve quantifiable variables that can be tested statistically ( statistical hypothesis ), 11 6) or express a relationship whose interlinks can be verified logically ( logical hypothesis ). 11 We provide examples of simple, complex, directional, non-directional, associative, causal, null, alternative, working, statistical, and logical hypotheses in quantitative research, as well as the definition of quantitative hypothesis-testing research in Table 3 .

Research questions in qualitative research

Unlike research questions in quantitative research, research questions in qualitative research are usually continuously reviewed and reformulated. The central question and associated subquestions are stated more than the hypotheses. 15 The central question broadly explores a complex set of factors surrounding the central phenomenon, aiming to present the varied perspectives of participants. 15

There are varied goals for which qualitative research questions are developed. These questions can function in several ways, such as to 1) identify and describe existing conditions ( contextual research question s); 2) describe a phenomenon ( descriptive research questions ); 3) assess the effectiveness of existing methods, protocols, theories, or procedures ( evaluation research questions ); 4) examine a phenomenon or analyze the reasons or relationships between subjects or phenomena ( explanatory research questions ); or 5) focus on unknown aspects of a particular topic ( exploratory research questions ). 5 In addition, some qualitative research questions provide new ideas for the development of theories and actions ( generative research questions ) or advance specific ideologies of a position ( ideological research questions ). 1 Other qualitative research questions may build on a body of existing literature and become working guidelines ( ethnographic research questions ). Research questions may also be broadly stated without specific reference to the existing literature or a typology of questions ( phenomenological research questions ), may be directed towards generating a theory of some process ( grounded theory questions ), or may address a description of the case and the emerging themes ( qualitative case study questions ). 15 We provide examples of contextual, descriptive, evaluation, explanatory, exploratory, generative, ideological, ethnographic, phenomenological, grounded theory, and qualitative case study research questions in qualitative research in Table 4 , and the definition of qualitative hypothesis-generating research in Table 5 .

Qualitative studies usually pose at least one central research question and several subquestions starting with How or What . These research questions use exploratory verbs such as explore or describe . These also focus on one central phenomenon of interest, and may mention the participants and research site. 15

Hypotheses in qualitative research

Hypotheses in qualitative research are stated in the form of a clear statement concerning the problem to be investigated. Unlike in quantitative research where hypotheses are usually developed to be tested, qualitative research can lead to both hypothesis-testing and hypothesis-generating outcomes. 2 When studies require both quantitative and qualitative research questions, this suggests an integrative process between both research methods wherein a single mixed-methods research question can be developed. 1

FRAMEWORKS FOR DEVELOPING RESEARCH QUESTIONS AND HYPOTHESES

Research questions followed by hypotheses should be developed before the start of the study. 1 , 12 , 14 It is crucial to develop feasible research questions on a topic that is interesting to both the researcher and the scientific community. This can be achieved by a meticulous review of previous and current studies to establish a novel topic. Specific areas are subsequently focused on to generate ethical research questions. The relevance of the research questions is evaluated in terms of clarity of the resulting data, specificity of the methodology, objectivity of the outcome, depth of the research, and impact of the study. 1 , 5 These aspects constitute the FINER criteria (i.e., Feasible, Interesting, Novel, Ethical, and Relevant). 1 Clarity and effectiveness are achieved if research questions meet the FINER criteria. In addition to the FINER criteria, Ratan et al. described focus, complexity, novelty, feasibility, and measurability for evaluating the effectiveness of research questions. 14

The PICOT and PEO frameworks are also used when developing research questions. 1 The following elements are addressed in these frameworks, PICOT: P-population/patients/problem, I-intervention or indicator being studied, C-comparison group, O-outcome of interest, and T-timeframe of the study; PEO: P-population being studied, E-exposure to preexisting conditions, and O-outcome of interest. 1 Research questions are also considered good if these meet the “FINERMAPS” framework: Feasible, Interesting, Novel, Ethical, Relevant, Manageable, Appropriate, Potential value/publishable, and Systematic. 14

As we indicated earlier, research questions and hypotheses that are not carefully formulated result in unethical studies or poor outcomes. To illustrate this, we provide some examples of ambiguous research question and hypotheses that result in unclear and weak research objectives in quantitative research ( Table 6 ) 16 and qualitative research ( Table 7 ) 17 , and how to transform these ambiguous research question(s) and hypothesis(es) into clear and good statements.

a These statements were composed for comparison and illustrative purposes only.

b These statements are direct quotes from Higashihara and Horiuchi. 16

a This statement is a direct quote from Shimoda et al. 17

The other statements were composed for comparison and illustrative purposes only.

CONSTRUCTING RESEARCH QUESTIONS AND HYPOTHESES

To construct effective research questions and hypotheses, it is very important to 1) clarify the background and 2) identify the research problem at the outset of the research, within a specific timeframe. 9 Then, 3) review or conduct preliminary research to collect all available knowledge about the possible research questions by studying theories and previous studies. 18 Afterwards, 4) construct research questions to investigate the research problem. Identify variables to be accessed from the research questions 4 and make operational definitions of constructs from the research problem and questions. Thereafter, 5) construct specific deductive or inductive predictions in the form of hypotheses. 4 Finally, 6) state the study aims . This general flow for constructing effective research questions and hypotheses prior to conducting research is shown in Fig. 1 .

Research questions are used more frequently in qualitative research than objectives or hypotheses. 3 These questions seek to discover, understand, explore or describe experiences by asking “What” or “How.” The questions are open-ended to elicit a description rather than to relate variables or compare groups. The questions are continually reviewed, reformulated, and changed during the qualitative study. 3 Research questions are also used more frequently in survey projects than hypotheses in experiments in quantitative research to compare variables and their relationships.

Hypotheses are constructed based on the variables identified and as an if-then statement, following the template, ‘If a specific action is taken, then a certain outcome is expected.’ At this stage, some ideas regarding expectations from the research to be conducted must be drawn. 18 Then, the variables to be manipulated (independent) and influenced (dependent) are defined. 4 Thereafter, the hypothesis is stated and refined, and reproducible data tailored to the hypothesis are identified, collected, and analyzed. 4 The hypotheses must be testable and specific, 18 and should describe the variables and their relationships, the specific group being studied, and the predicted research outcome. 18 Hypotheses construction involves a testable proposition to be deduced from theory, and independent and dependent variables to be separated and measured separately. 3 Therefore, good hypotheses must be based on good research questions constructed at the start of a study or trial. 12

In summary, research questions are constructed after establishing the background of the study. Hypotheses are then developed based on the research questions. Thus, it is crucial to have excellent research questions to generate superior hypotheses. In turn, these would determine the research objectives and the design of the study, and ultimately, the outcome of the research. 12 Algorithms for building research questions and hypotheses are shown in Fig. 2 for quantitative research and in Fig. 3 for qualitative research.

EXAMPLES OF RESEARCH QUESTIONS FROM PUBLISHED ARTICLES

• EXAMPLE 1. Descriptive research question (quantitative research)
• - Presents research variables to be assessed (distinct phenotypes and subphenotypes)
• “BACKGROUND: Since COVID-19 was identified, its clinical and biological heterogeneity has been recognized. Identifying COVID-19 phenotypes might help guide basic, clinical, and translational research efforts.
• RESEARCH QUESTION: Does the clinical spectrum of patients with COVID-19 contain distinct phenotypes and subphenotypes? ” 19
• EXAMPLE 2. Relationship research question (quantitative research)
• - Shows interactions between dependent variable (static postural control) and independent variable (peripheral visual field loss)
• “Background: Integration of visual, vestibular, and proprioceptive sensations contributes to postural control. People with peripheral visual field loss have serious postural instability. However, the directional specificity of postural stability and sensory reweighting caused by gradual peripheral visual field loss remain unclear.
• Research question: What are the effects of peripheral visual field loss on static postural control ?” 20
• EXAMPLE 3. Comparative research question (quantitative research)
• - Clarifies the difference among groups with an outcome variable (patients enrolled in COMPERA with moderate PH or severe PH in COPD) and another group without the outcome variable (patients with idiopathic pulmonary arterial hypertension (IPAH))
• “BACKGROUND: Pulmonary hypertension (PH) in COPD is a poorly investigated clinical condition.
• RESEARCH QUESTION: Which factors determine the outcome of PH in COPD?
• STUDY DESIGN AND METHODS: We analyzed the characteristics and outcome of patients enrolled in the Comparative, Prospective Registry of Newly Initiated Therapies for Pulmonary Hypertension (COMPERA) with moderate or severe PH in COPD as defined during the 6th PH World Symposium who received medical therapy for PH and compared them with patients with idiopathic pulmonary arterial hypertension (IPAH) .” 21
• EXAMPLE 4. Exploratory research question (qualitative research)
• - Explores areas that have not been fully investigated (perspectives of families and children who receive care in clinic-based child obesity treatment) to have a deeper understanding of the research problem
• “Problem: Interventions for children with obesity lead to only modest improvements in BMI and long-term outcomes, and data are limited on the perspectives of families of children with obesity in clinic-based treatment. This scoping review seeks to answer the question: What is known about the perspectives of families and children who receive care in clinic-based child obesity treatment? This review aims to explore the scope of perspectives reported by families of children with obesity who have received individualized outpatient clinic-based obesity treatment.” 22
• EXAMPLE 5. Relationship research question (quantitative research)
• - Defines interactions between dependent variable (use of ankle strategies) and independent variable (changes in muscle tone)
• “Background: To maintain an upright standing posture against external disturbances, the human body mainly employs two types of postural control strategies: “ankle strategy” and “hip strategy.” While it has been reported that the magnitude of the disturbance alters the use of postural control strategies, it has not been elucidated how the level of muscle tone, one of the crucial parameters of bodily function, determines the use of each strategy. We have previously confirmed using forward dynamics simulations of human musculoskeletal models that an increased muscle tone promotes the use of ankle strategies. The objective of the present study was to experimentally evaluate a hypothesis: an increased muscle tone promotes the use of ankle strategies. Research question: Do changes in the muscle tone affect the use of ankle strategies ?” 23

EXAMPLES OF HYPOTHESES IN PUBLISHED ARTICLES

• EXAMPLE 1. Working hypothesis (quantitative research)
• - A hypothesis that is initially accepted for further research to produce a feasible theory
• “As fever may have benefit in shortening the duration of viral illness, it is plausible to hypothesize that the antipyretic efficacy of ibuprofen may be hindering the benefits of a fever response when taken during the early stages of COVID-19 illness .” 24
• “In conclusion, it is plausible to hypothesize that the antipyretic efficacy of ibuprofen may be hindering the benefits of a fever response . The difference in perceived safety of these agents in COVID-19 illness could be related to the more potent efficacy to reduce fever with ibuprofen compared to acetaminophen. Compelling data on the benefit of fever warrant further research and review to determine when to treat or withhold ibuprofen for early stage fever for COVID-19 and other related viral illnesses .” 24
• EXAMPLE 2. Exploratory hypothesis (qualitative research)
• - Explores particular areas deeper to clarify subjective experience and develop a formal hypothesis potentially testable in a future quantitative approach
• “We hypothesized that when thinking about a past experience of help-seeking, a self distancing prompt would cause increased help-seeking intentions and more favorable help-seeking outcome expectations .” 25
• “Conclusion
• Although a priori hypotheses were not supported, further research is warranted as results indicate the potential for using self-distancing approaches to increasing help-seeking among some people with depressive symptomatology.” 25
• EXAMPLE 3. Hypothesis-generating research to establish a framework for hypothesis testing (qualitative research)
• “We hypothesize that compassionate care is beneficial for patients (better outcomes), healthcare systems and payers (lower costs), and healthcare providers (lower burnout). ” 26
• Compassionomics is the branch of knowledge and scientific study of the effects of compassionate healthcare. Our main hypotheses are that compassionate healthcare is beneficial for (1) patients, by improving clinical outcomes, (2) healthcare systems and payers, by supporting financial sustainability, and (3) HCPs, by lowering burnout and promoting resilience and well-being. The purpose of this paper is to establish a scientific framework for testing the hypotheses above . If these hypotheses are confirmed through rigorous research, compassionomics will belong in the science of evidence-based medicine, with major implications for all healthcare domains.” 26
• EXAMPLE 4. Statistical hypothesis (quantitative research)
• - An assumption is made about the relationship among several population characteristics ( gender differences in sociodemographic and clinical characteristics of adults with ADHD ). Validity is tested by statistical experiment or analysis ( chi-square test, Students t-test, and logistic regression analysis)
• “Our research investigated gender differences in sociodemographic and clinical characteristics of adults with ADHD in a Japanese clinical sample. Due to unique Japanese cultural ideals and expectations of women's behavior that are in opposition to ADHD symptoms, we hypothesized that women with ADHD experience more difficulties and present more dysfunctions than men . We tested the following hypotheses: first, women with ADHD have more comorbidities than men with ADHD; second, women with ADHD experience more social hardships than men, such as having less full-time employment and being more likely to be divorced.” 27
• “Statistical Analysis
• ( text omitted ) Between-gender comparisons were made using the chi-squared test for categorical variables and Students t-test for continuous variables…( text omitted ). A logistic regression analysis was performed for employment status, marital status, and comorbidity to evaluate the independent effects of gender on these dependent variables.” 27

EXAMPLES OF HYPOTHESIS AS WRITTEN IN PUBLISHED ARTICLES IN RELATION TO OTHER PARTS

• EXAMPLE 1. Background, hypotheses, and aims are provided
• “Pregnant women need skilled care during pregnancy and childbirth, but that skilled care is often delayed in some countries …( text omitted ). The focused antenatal care (FANC) model of WHO recommends that nurses provide information or counseling to all pregnant women …( text omitted ). Job aids are visual support materials that provide the right kind of information using graphics and words in a simple and yet effective manner. When nurses are not highly trained or have many work details to attend to, these job aids can serve as a content reminder for the nurses and can be used for educating their patients (Jennings, Yebadokpo, Affo, & Agbogbe, 2010) ( text omitted ). Importantly, additional evidence is needed to confirm how job aids can further improve the quality of ANC counseling by health workers in maternal care …( text omitted )” 28
• “ This has led us to hypothesize that the quality of ANC counseling would be better if supported by job aids. Consequently, a better quality of ANC counseling is expected to produce higher levels of awareness concerning the danger signs of pregnancy and a more favorable impression of the caring behavior of nurses .” 28
• “This study aimed to examine the differences in the responses of pregnant women to a job aid-supported intervention during ANC visit in terms of 1) their understanding of the danger signs of pregnancy and 2) their impression of the caring behaviors of nurses to pregnant women in rural Tanzania.” 28
• EXAMPLE 2. Background, hypotheses, and aims are provided
• “We conducted a two-arm randomized controlled trial (RCT) to evaluate and compare changes in salivary cortisol and oxytocin levels of first-time pregnant women between experimental and control groups. The women in the experimental group touched and held an infant for 30 min (experimental intervention protocol), whereas those in the control group watched a DVD movie of an infant (control intervention protocol). The primary outcome was salivary cortisol level and the secondary outcome was salivary oxytocin level.” 29
• “ We hypothesize that at 30 min after touching and holding an infant, the salivary cortisol level will significantly decrease and the salivary oxytocin level will increase in the experimental group compared with the control group .” 29
• EXAMPLE 3. Background, aim, and hypothesis are provided
• “In countries where the maternal mortality ratio remains high, antenatal education to increase Birth Preparedness and Complication Readiness (BPCR) is considered one of the top priorities [1]. BPCR includes birth plans during the antenatal period, such as the birthplace, birth attendant, transportation, health facility for complications, expenses, and birth materials, as well as family coordination to achieve such birth plans. In Tanzania, although increasing, only about half of all pregnant women attend an antenatal clinic more than four times [4]. Moreover, the information provided during antenatal care (ANC) is insufficient. In the resource-poor settings, antenatal group education is a potential approach because of the limited time for individual counseling at antenatal clinics.” 30
• “This study aimed to evaluate an antenatal group education program among pregnant women and their families with respect to birth-preparedness and maternal and infant outcomes in rural villages of Tanzania.” 30
• “ The study hypothesis was if Tanzanian pregnant women and their families received a family-oriented antenatal group education, they would (1) have a higher level of BPCR, (2) attend antenatal clinic four or more times, (3) give birth in a health facility, (4) have less complications of women at birth, and (5) have less complications and deaths of infants than those who did not receive the education .” 30

Research questions and hypotheses are crucial components to any type of research, whether quantitative or qualitative. These questions should be developed at the very beginning of the study. Excellent research questions lead to superior hypotheses, which, like a compass, set the direction of research, and can often determine the successful conduct of the study. Many research studies have floundered because the development of research questions and subsequent hypotheses was not given the thought and meticulous attention needed. The development of research questions and hypotheses is an iterative process based on extensive knowledge of the literature and insightful grasp of the knowledge gap. Focused, concise, and specific research questions provide a strong foundation for constructing hypotheses which serve as formal predictions about the research outcomes. Research questions and hypotheses are crucial elements of research that should not be overlooked. They should be carefully thought of and constructed when planning research. This avoids unethical studies and poor outcomes by defining well-founded objectives that determine the design, course, and outcome of the study.

Disclosure: The authors have no potential conflicts of interest to disclose.

Author Contributions:

• Conceptualization: Barroga E, Matanguihan GJ.
• Methodology: Barroga E, Matanguihan GJ.
• Writing - original draft: Barroga E, Matanguihan GJ.
• Writing - review & editing: Barroga E, Matanguihan GJ.

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Creating a Good Research Question

• Advice & Growth
• Process in Practice

Successful translation of research begins with a strong question. How do you get started? How do good research questions evolve? And where do you find inspiration to generate good questions in the first place?  It’s helpful to understand existing frameworks, guidelines, and standards, as well as hear from researchers who utilize these strategies in their own work.

In the fall and winter of 2020, Naomi Fisher, MD, conducted 10 interviews with clinical and translational researchers at Harvard University and affiliated academic healthcare centers, with the purpose of capturing their experiences developing good research questions. The researchers featured in this project represent various specialties, drawn from every stage of their careers. Below you will find clips from their interviews and additional resources that highlight how to get started, as well as helpful frameworks and factors to consider. Additionally, visit the Advice & Growth section to hear candid advice and explore the Process in Practice section to hear how researchers have applied these recommendations to their published research.

• Naomi Fisher, MD , is associate professor of medicine at Harvard Medical School (HMS), and clinical staff at Brigham and Women’s Hospital (BWH). Fisher is founder and director of Hypertension Services and the Hypertension Specialty Clinic at the BWH, where she is a renowned endocrinologist. She serves as a faculty director for communication-related Boundary-Crossing Skills for Research Careers webinar sessions and the Writing and Communication Center .
• Christopher Gibbons, MD , is associate professor of neurology at HMS, and clinical staff at Beth Israel Deaconess Medical Center (BIDMC) and Joslin Diabetes Center. Gibbons’ research focus is on peripheral and autonomic neuropathies.
• Clare Tempany-Afdhal, MD , is professor of radiology at HMS and the Ferenc Jolesz Chair of Research, Radiology at BWH. Her major areas of research are MR imaging of the pelvis and image- guided therapy.
• David Sykes, MD, PhD , is assistant professor of medicine at Massachusetts General Hospital (MGH), he is also principal investigator at the Sykes Lab at MGH. His special interest area is rare hematologic conditions.
• Elliot Israel, MD , is professor of medicine at HMS, director of the Respiratory Therapy Department, the director of clinical research in the Pulmonary and Critical Care Medical Division and associate physician at BWH. Israel’s research interests include therapeutic interventions to alter asthmatic airway hyperactivity and the role of arachidonic acid metabolites in airway narrowing.
• Jonathan Williams, MD, MMSc , is assistant professor of medicine at HMS, and associate physician at BWH. He focuses on endocrinology, specifically unravelling the intricate relationship between genetics and environment with respect to susceptibility to cardiometabolic disease.
• Junichi Tokuda, PhD , is associate professor of radiology at HMS, and is a research scientist at the Department of Radiology, BWH. Tokuda is particularly interested in technologies to support image-guided “closed-loop” interventions. He also serves as a principal investigator leading several projects funded by the National Institutes of Health and industry.
• Osama Rahma, MD , is assistant professor of medicine at HMS and clinical staff member in medical oncology at Dana-Farber Cancer Institute (DFCI). Rhama is currently a principal investigator at the Center for Immuno-Oncology and Gastroenterology Cancer Center at DFCI. His research focus is on drug development of combinational immune therapeutics.
• Sharmila Dorbala, MD, MPH , is professor of radiology at HMS and clinical staff at BWH in cardiovascular medicine and radiology. She is also the president of the American Society of Nuclear Medicine. Dorbala’s specialty is using nuclear medicine for cardiovascular discoveries.
• Subha Ramani, PhD, MBBS, MMed , is associate professor of medicine at HMS, as well as associate physician in the Division of General Internal Medicine and Primary Care at BWH. Ramani’s scholarly interests focus on innovative approaches to teaching, learning and assessment of clinical trainees, faculty development in teaching, and qualitative research methods in medical education.
• Ursula Kaiser, MD , is professor at HMS and chief of the Division of Endocrinology, Diabetes and Hypertension, and senior physician at BWH. Kaiser’s research focuses on understanding the molecular mechanisms by which pulsatile gonadotropin-releasing hormone regulates the expression of luteinizing hormone and follicle-stimulating hormone genes.

Insights on Creating a Good Research Question

Play Junichi Tokuda video

Play Ursula Kaiser video

Start Successfully: Build the Foundation of a Good Research Question

Start Successfully Resources

Ideation in Device Development: Finding Clinical Need Josh Tolkoff, MS A lecture explaining the critical importance of identifying a compelling clinical need before embarking on a research project. Play Ideation in Device Development video .

Radical Innovation Jeff Karp, PhD This ThinkResearch podcast episode focuses on one researcher’s approach using radical simplicity to break down big problems and questions. Play Radical Innovation .

Using Healthcare Data: How can Researchers Come up with Interesting Questions? Anupam Jena, MD, PhD Another ThinkResearch podcast episode addresses how to discover good research questions by using a backward design approach which involves analyzing big data and allowing the research question to unfold from findings. Play Using Healthcare Data .

Important Factors: Consider Feasibility and Novelty

Refining Your Research Question 

Play video of Clare Tempany-Afdhal

Play Elliott Israel video

Frameworks and Structure: Evaluate Research Questions Using Tools and Techniques

Frameworks and Structure Resources

Designing Clinical Research Hulley et al. A comprehensive and practical guide to clinical research, including the FINER framework for evaluating research questions. Learn more about the book .

Translational Medicine Library Guide Queens University Library An introduction to popular frameworks for research questions, including FINER and PICO. Review translational medicine guide .

Asking a Good T3/T4 Question  Niteesh K. Choudhry, MD, PhD This video explains the PICO framework in practice as participants in a workshop propose research questions that compare interventions. Play Asking a Good T3/T4 Question video

Introduction to Designing & Conducting Mixed Methods Research An online course that provides a deeper dive into mixed methods’ research questions and methodologies. Learn more about the course

Network and Support: Find the Collaborators and Stakeholders to Help Evaluate Research Questions

Network & Support Resource

Bench-to-bedside, Bedside-to-bench Christopher Gibbons, MD In this lecture, Gibbons shares his experience of bringing research from bench to bedside, and from bedside to bench. His talk highlights the formation and evolution of research questions based on clinical need. Play Bench-to-bedside. 

• Jul 7, 2020

How to Write a Science Research Question

Humans are a very curious species. We are always asking questions. But the way we formulate a question is very important when we think about science and research. Here we’ll lay out how to form a science research question and the concepts needed to formulate a good research question. Luckily, we’ve got some handy visuals to help you along.

In order to inquire about the world, produce new information, and solve a mystery of about the natural world, we always use the scientific process to inform research questions. So, we need to keep in mind the steps of the scientific process :

Observation

Data to be obtained

Ways to analyze data

Conclusions to obtain from the question

First, clearly define your population and your variables.

Now, what is a population ? Defined in ecologic terms, a population are all the individuals of one species in a given area (e.g. population of deer, leatherback turtles, spruce trees, mushrooms, etc.).

Now, what is a variable ? A variable is any factor, trait, or condition that can exist in differing amounts or types (e.g. length, quantity, temperature, speed, mass, distance, depth, etc.).

So, using different combinations of these two components, we can create three different types of research questions: descriptive, comparative, and correlative. These three types also match three of the modern research methodologies. 

Descriptive field investigations involve describing and/or quantifying parts of a natural system. Includes generally 1 population and one distinctive variable (figure 1). Examples of descriptive research questions:

How many pine trees are in the Mammoth Hot Springs area?

What is the wolf pack’s distribution range?

How frequently do humpback whales breed?    

Comparative field investigations involve collecting data on different populations/organisms, or under different conditions (e.g., times of year, locations), to make a comparison. Includes two or more populations and one distinctive variable (figure 2). Examples of comparative research questions:

Is there a difference in body length between male and female tortoises?

Is there a difference in diversity of fungi that live in the forest compared with non-forested areas?  

Correlative field investigations involve measuring or observing two variables and searching for a relationship between them for a distinctive population (figure 3). Examples of correlative research questions:

What is the relationship between length of the tail and age in humpback whales?

How does a spider’s reproduction rate change with a change in season?

To practice how to write a research question, we suggest the following steps:

Find a nice place where you can be alone and connected with nature. Bring nothing else but a journal and a pencil. Take a few moments to breath and observe everything that surrounds you. Use all of your senses to obtain information from your surroundings: smell the flowers around you, feel the leaves, hear the birds, and recognize all the life.

Choose a population that is around you and that interests you (flowers, trees, insects, rocks), and think about what would you like to know about that population. Write down what you want to study from that population (your variable). It is easier to choose the population first and the variables second. Think about a feasible and simple measurement. One easy measurement is counting, since it doesn’t require an instrument.

Write down your question using your population and variable. Remember to write a question that is going to be simple, measurable, attainable, relevant, and limited to a particular time and place. Avoid why questions.

Next, write a prediction that answers your question. This is your hypothesis .

Now that you have a defined population, measure your variable, and obtain data. Don’t forget to write it down in your journal.

Finally, compare your hypothesis with your actual data and write a conclusion about your findings.

These simple and fun steps will help you create great questions that will lead you to find interesting answers and discoveries. But remember, this process not only works for scientific questions but also for daily issues, such as why the car stopped working. You can use it to investigate local environmental problems and provide possible solutions for the benefit of your community and future generations.

You can find more information about this topic in: Ryken, A. E., Otto, P., Pritchard, K., & Owens, K. (2007). Field investigations: Using outdoor environments to foster student learning of scientific processes . Pacific Education Institute. 

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80+ Science Research Paper Topics Ideas For Students

Essay writing or writing dissertation is an integral part of education at any level, middle school, high school, or college. Some of the most common essays are on science research topics, and they are also quite interesting. However, choosing research paper topics isn’t as straightforward as you’d like. You’ll need to carry out a survey on and draw inspiration from several scientific research topics before finally choosing one. Choosing science topics, especially if they are argumentative essay topics , to write about can be a frustrating task, especially when science is a pretty wide subject. If you need inspiration on interesting science topics, we’ll give you some science research paper ideas. But, first, let’s talk about how to choose the best science research paper topics – it makes things easier.

What Are Some Science Topics You Can Write About?

Interesting science research topics, ideas of science research topics for high school students, science research topics for college students, science research topics for middle school, scientific research question examples, science presentation ideas, cool science topics to research, ideas of scientific topics for research on nanotechnology, fascinating ideas for science research projects, interesting science topics for high school research papers, tips for choosing science research topics.

Being a very broad subject, students often find choosing a science topic for a research paper difficult. However, the secret is knowing what scientific research questions will make for a good paper, and what people will want to read. So, when choosing science topics for papers, here are tips you can follow to make the task easier.

• Choose cool science topics you’re interested in and that’ll interest your readers.
• Search online for research question examples science for ideas on what your paper should be about.
• Avoid choosing too-broad research topics for high school, to ensure your work is well detailed.
• Consider contemporary scientific research questions concerning recent happenings; they can be fun to write
• Read your notes and online academic papers for inspiration on good science research paper topics.
• Choose simple but highly informative research topics for high school students.
• Choose good science topics you have some knowledge of and can confidently talk about.
• Learn how to choose science topics for high school to make things easier.
• Be familiar with the dos and don’ts of choosing scientific research paper topics.
• Choose a scientific topic for research papers that has enough accessible information.

The Dos and Don’ts of Choosing Science Topics

Knowing the dos and don’ts of choosing a science title helps you select a good topic and ultimately write an outstanding paper. So, when searching for science topics for presentations,

• Do understand that there are different topics in science you can research on;
• Do read extensively for science research paper ideas; it helps you know what to write about;
• Don’t include words like “Research of” or “Study of” in your chosen science topics to research;
• Don’t choose high school science research paper topics with scanty or inaccessible information available;
• Do check online for interesting science research ideas on how to write your paper;
• Feel free to ask your instructor, colleagues, or seniors for scientific research ideas.

When searching for interesting science topics or social media research topics related to science to writing on, you will find different ones on different subjects, which can be confusing. You can follow the tips we listed for choosing science-related topics for a research paper. Meanwhile, here are some science paper topics you can use if none is forthcoming.

• Is there a move for the Covid-19 vaccine?
• What “flattening the curve” means
• Molecular evidence of humans interbreeding with Neanderthals
• Impact of cardio exercise on heart health
• The importance of exploring the solar system
• Can a comet strike the earth?
• The Hubble Space Telescope
• Top ten chemistry careers
• Acid rain effect aquatic plants’ growth
• Room color and human behavior
• How can plants grow in pots?
• Water’s surface tension weight capacity
• What does the paleo diet mean?
• Is Pluto still a planet?
• The future of commercial space flight
• Do you inherit fingerprint patterns?
• Ways in which handwashing prevents the spread of the Covid-19 virus
• Molecular biological research on rare genetic disorders impact on understanding cancer
• Do men pass on genetic abnormalities to their posterity as they age?
• How can men’s exercise affect the traits they pass on to their children?
• Is there really life on Mars; has there ever been?
• Ways of solving the problem of junk space
• The importance of Dark Matter
• Black holes
• Different ways to keep ice from defrosting
• Are pet hairs harmful to the human body?
• Some of the germs you’ve seen in your school
• The effect of music on your assimilation ability
• The types of food dogs prefer the best
• Good hygienic practices for keeping clean
• Foods that develop molds the fastest
• How different body parts aid the effective functioning of the system
• Do worms in the soil really affect plant growth and how?
• Can light brightness make plants grow well?
• What kinds of fertilizers work best, chemical or natural?
• Can mice (or any animal of your choice) learn?
• How can age affect the human reaction?
• Why does water boil faster when put in salt?
• Can food affect the heart, how?
• Can background noise interfere with learning and assimilation?
• Can Higgs Boson destroy the universe?
• Effects of sunspots on man
• Should humans live in space?
• The most important technological innovations in medicinal chemistry in recent years
• The danger of chemicals emitted from pharmaceutical companies
• The importance of big data and bioinformatics to chemical research
• The sugar chemistry behind making candy
• Biomacromolecules
• Trends in India’s medicinal chemistry research
• Nuclear fusion
• Reproduction in mammals
• How do fish mate?
• How useful are science museums in teaching science?
• Why do birds have beautiful feathers?
• The safety of offshore drilling
• The importance of climate change legislation
• Hydraulic fracking’s negative effects
• Uses of microelectronics
• Nanotechnology in medicine
• Nanotechnology for cancer treatment
• Can nanofibers repair brain injuries?
• Effect of nanomedicine on human lifespan
• Nanomaterial
• How nanotechnology helps in patient diagnosis
• How to reduce antibiotic use in agriculture
• The ethics of stem cell research
• The best leukemia treatment
• Gene therapy
• Causes of skin cancer
• Colonoscopy testing on colon cancer
• Why eliminating malaria is difficult
• The possibility of predicting the next pandemic
• Do childhood vaccines prevent diseases?
• How cells shield the body against diseases
• Should wild animals interact with humans?
• Are self-driving cars good?
• Regulating sugar use
• Different types of headaches
• Can migraine cause death?
• The ideal weight for living long

Feel free to choose from this scientific research topics list for your science research paper. There are many things to research where science is concerned, including stem research topics , among others. There is no shortage of scientific topics to research and choosing the best one gets easy when you know how to. If you’ve chosen a topic and you need help writing on them, you can contact our professional writing service. We have a team of experts who can write on any science topic and ensure you meet your deadline.

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Biggest Questions in Science

At its essence, science pursues knowledge by asking and answering questions. In this collection, Scientific American Custom Media, along with our partners at The Kavli Prize, explore the work of scientists who pursue the biggest questions in neuroscience, nanoscience and astrophysics. From the atomic scale to the galactic, the truths these scientists have uncovered are fundamental, and they have reshaped our understanding of how the universe works.

Interactive: Visualizing New Frontiers

Interactive: The Big Bang Reborn

Interactive: Galaxy Clusters and the Evolving Universe

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The Biggest Questions in Science

An editorially independent special report on research into fundamental scientific mysteries, produced with support from The Kavli Prize

June 1, 2018 — Madhusree Mukerjee

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Greater Good Science Center • Magazine • In Action • In Education

Big Ideas Articles & More

10 questions to ask about scientific studies, never take a study at face value, including one you read about in greater good .

Here at Greater Good , we cover research into social and emotional well-being, and we try to help people apply findings to their personal and professional lives. We are well aware that our business is a tricky one.

Summarizing scientific studies and applying them to people’s lives isn’t just difficult for the obvious reasons, like understanding and then explaining scientific jargon or methods to non-specialists. It’s also the case that context gets lost when we translate findings into stories, tips, and tools for a more meaningful life, especially when we push it all through the nuance-squashing machine of the Internet. Many people never read past the headlines, which intrinsically aim to overgeneralize and provoke interest. Because our articles can never be as comprehensive as the original studies, they almost always omit some crucial caveats, such as limitations acknowledged by the researchers. To get those, you need access to the studies themselves.

And it’s very common for findings to seem to contradict each other. For example, we recently covered an experiment that suggests stress reduces empathy—after having previously discussed other research suggesting that stress-prone people can be more empathic. Some readers asked: Which one is correct? (You’ll find my answer here .)

But probably the most important missing piece is the future. That may sound like a funny thing to say, but, in fact, a new study is not worth the PDF it’s printed on until its findings are replicated and validated by other studies—studies that haven’t yet happened. An experiment is merely interesting until time and testing turns its finding into a fact.

Scientists know this, and they are trained to react very skeptically to every new paper. They also expect to be greeted with skepticism when they present findings. Trust is good, but science isn’t about trust. It’s about verification.

However, journalists like me, and members of the general public, are often prone to treat every new study as though it represents the last word on the question addressed. This particular issue was highlighted last week by—wait for it—a new study that tried to reproduce 100 prior psychological studies to see if their findings held up. The result of the three-year initiative is chilling: The team, led by University of Virginia psychologist Brian Nosek, got the same results in only 36 percent of the experiments they replicated. This has led to some predictably provocative, overgeneralizing headlines implying that we shouldn’t take psychology seriously.

I don’t agree.

Despite all the mistakes and overblown claims and criticism and contradictions and arguments—or perhaps because of them—our knowledge of human brains and minds has expanded dramatically during the past century. Psychology and neuroscience have documented phenomena like cognitive dissonance, identified many of the brain structures that support our emotions, and proved the placebo effect and other dimensions of the mind-body connection, among other findings that have been tested over and over again.

These discoveries have helped us understand and treat the true causes of many illnesses. I’ve heard it argued that rising rates of diagnoses of mental illness constitute evidence that psychology is failing, but in fact, the opposite is true: We’re seeing more and better diagnoses of problems that would have compelled previous generations to dismiss people as “stupid” or “crazy” or “hyper” or “blue.” The important thing to bear in mind is that it took a very, very long time for science to come to these insights and treatments, following much trial and error.

Science isn’t a faith, but rather a method that takes time to unfold. That’s why it’s equally wrong to uncritically embrace everything you read, including what you are reading on this page.

Given the complexities and ambiguities of the scientific endeavor, is it possible for a non-scientist to strike a balance between wholesale dismissal and uncritical belief? Are there red flags to look for when you read about a study on a site like Greater Good or in a popular self-help book? If you do read one of the actual studies, how should you, as a non-scientist, gauge its credibility?

I drew on my own experience as a science journalist, and surveyed my colleagues here at the UC Berkeley Greater Good Science Center. We came up 10 questions you might ask when you read about the latest scientific findings. These are also questions we ask ourselves, before we cover a study.

1. Did the study appear in a peer-reviewed journal?

Peer review—submitting papers to other experts for independent review before acceptance—remains one of the best ways we have for ascertaining the basic seriousness of the study, and many scientists describe peer review as a truly humbling crucible. If a study didn’t go through this process, for whatever reason, it should be taken with a much bigger grain of salt.

2. Who was studied, where?

Animal experiments tell scientists a lot, but their applicability to our daily human lives will be limited. Similarly, if researchers only studied men, the conclusions might not be relevant to women, and vice versa.

This was actually a huge problem with Nosek’s effort to replicate other people’s experiments. In trying to replicate one German study, for example, they had to use different maps (ones that would be familiar to University of Virginia students) and change a scale measuring aggression to reflect American norms. This kind of variance could explain the different results. It may also suggest the limits of generalizing the results from one study to other populations not included within that study.

As a matter of approach, readers must remember that many psychological studies rely on WEIRD (Western, educated, industrialized, rich and democratic) samples, mainly college students, which creates an in-built bias in the discipline’s conclusions. Does that mean you should dismiss Western psychology? Of course not. It’s just the equivalent of a “Caution” or “Yield” sign on the road to understanding.

3. How big was the sample?

In general, the more participants in a study, the more valid its results. That said, a large sample is sometimes impossible or even undesirable for certain kinds of studies. This is especially true in expensive neuroscience experiments involving functional magnetic resonance imaging, or fMRI, scans.

And many mindfulness studies have scanned the brains of people with many thousands of hours of meditation experience—a relatively small group. Even in those cases, however, a study that looks at 30 experienced meditators is probably more solid than a similar one that scanned the brains of only 15.

4. Did the researchers control for key differences?

Diversity or gender balance aren’t necessarily virtues in a research study; it’s actually a good thing when a study population is as homogenous as possible, because it allows the researchers to limit the number of differences that might affect the result. A good researcher tries to compare apples to apples, and control for as many differences as possible in her analysis.

5. Was there a control group?

One of the first things to look for in methodology is whether the sample is randomized and involved a control group; this is especially important if a study is to suggest that a certain variable might actually cause a specific outcome, rather than just be correlated with it (see next point).

For example, were some in the sample randomly assigned a specific meditation practice while others weren’t? If the sample is large enough, randomized trials can produce solid conclusions. But, sometimes, a study will not have a control group because it’s ethically impossible. (Would people still divert a trolley to kill one person in order to save five lives, if their decision killed a real person, instead of just being a thought experiment? We’ll never know for sure!)

The conclusions may still provide some insight, but they need to be kept in perspective.

6. Did the researchers establish causality, correlation, dependence, or some other kind of relationship?

I often hear “Correlation is not causation” shouted as a kind of battle cry, to try to discredit a study. But correlation—the degree to which two or more measurements seem to change at the same time—is important, and is one step in eventually finding causation—that is, establishing a change in one variable directly triggers a change in another.

The important thing is to correctly identify the relationship.

7. Is the journalist, or even the scientist, overstating the result?

Language that suggests a fact is “proven” by one study or which promotes one solution for all people is most likely overstating the case. Sweeping generalizations of any kind often indicate a lack of humility that should be a red flag to readers. A study may very well “suggest” a certain conclusion but it rarely, if ever, “proves” it.

This is why we use a lot of cautious, hedging language in Greater Good , like “might” or “implies.”

8. Is there any conflict of interest suggested by the funding or the researchers’ affiliations?

A recent study found that you could drink lots of sugary beverages without fear of getting fat, as long as you exercised. The funder? Coca Cola, which eagerly promoted the results. This doesn’t mean the results are wrong. But it does suggest you should seek a second opinion .

9. Does the researcher seem to have an agenda?

Readers could understandably be skeptical of mindfulness meditation studies promoted by practicing Buddhists or experiments on the value of prayer conducted by Christians. Again, it doesn’t automatically mean that the conclusions are wrong. It does, however, raise the bar for peer review and replication. For example, it took hundreds of experiments before we could begin saying with confidence that mindfulness can indeed reduce stress.

10. Do the researchers acknowledge limitations and entertain alternative explanations?

Is the study focused on only one side of the story or one interpretation of the data? Has it failed to consider or refute alternative explanations? Do they demonstrate awareness of which questions are answered and which aren’t by their methods?

I summarize my personal stance as a non-scientist toward scientific findings as this: Curious, but skeptical. I take it all seriously and I take it all with a grain of salt. I judge it against my experience, knowing that my experience creates bias. I try to cultivate humility, doubt, and patience. I don’t always succeed; when I fail, I try to admit fault and forgive myself. My own understanding is imperfect, and I remind myself that one study is only one step in understanding. Above all, I try to bear in mind that science is a process, and that conclusions always raise more questions for us to answer.

About the Author

Jeremy Adam Smith

Uc berkeley.

Jeremy Adam Smith edits the GGSC's online magazine, Greater Good . He is also the author or coeditor of five books, including The Daddy Shift , Are We Born Racist? , and (most recently) The Gratitude Project: How the Science of Thankfulness Can Rewire Our Brains for Resilience, Optimism, and the Greater Good . Before joining the GGSC, Jeremy was a John S. Knight Journalism Fellow at Stanford University.

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Sat / act prep online guides and tips, 113 great research paper topics.

General Education

One of the hardest parts of writing a research paper can be just finding a good topic to write about. Fortunately we've done the hard work for you and have compiled a list of 113 interesting research paper topics. They've been organized into ten categories and cover a wide range of subjects so you can easily find the best topic for you.

In addition to the list of good research topics, we've included advice on what makes a good research paper topic and how you can use your topic to start writing a great paper.

What Makes a Good Research Paper Topic?

Not all research paper topics are created equal, and you want to make sure you choose a great topic before you start writing. Below are the three most important factors to consider to make sure you choose the best research paper topics.

#1: It's Something You're Interested In

A paper is always easier to write if you're interested in the topic, and you'll be more motivated to do in-depth research and write a paper that really covers the entire subject. Even if a certain research paper topic is getting a lot of buzz right now or other people seem interested in writing about it, don't feel tempted to make it your topic unless you genuinely have some sort of interest in it as well.

#2: There's Enough Information to Write a Paper

Even if you come up with the absolute best research paper topic and you're so excited to write about it, you won't be able to produce a good paper if there isn't enough research about the topic. This can happen for very specific or specialized topics, as well as topics that are too new to have enough research done on them at the moment. Easy research paper topics will always be topics with enough information to write a full-length paper.

Trying to write a research paper on a topic that doesn't have much research on it is incredibly hard, so before you decide on a topic, do a bit of preliminary searching and make sure you'll have all the information you need to write your paper.

#3: It Fits Your Teacher's Guidelines

Don't get so carried away looking at lists of research paper topics that you forget any requirements or restrictions your teacher may have put on research topic ideas. If you're writing a research paper on a health-related topic, deciding to write about the impact of rap on the music scene probably won't be allowed, but there may be some sort of leeway. For example, if you're really interested in current events but your teacher wants you to write a research paper on a history topic, you may be able to choose a topic that fits both categories, like exploring the relationship between the US and North Korea. No matter what, always get your research paper topic approved by your teacher first before you begin writing.

113 Good Research Paper Topics

Below are 113 good research topics to help you get you started on your paper. We've organized them into ten categories to make it easier to find the type of research paper topics you're looking for.

Arts/Culture

• Discuss the main differences in art from the Italian Renaissance and the Northern Renaissance .
• Analyze the impact a famous artist had on the world.
• How is sexism portrayed in different types of media (music, film, video games, etc.)? Has the amount/type of sexism changed over the years?
• How has the music of slaves brought over from Africa shaped modern American music?
• How has rap music evolved in the past decade?
• How has the portrayal of minorities in the media changed?

Current Events

• What have been the impacts of China's one child policy?
• How have the goals of feminists changed over the decades?
• How has the Trump presidency changed international relations?
• Analyze the history of the relationship between the United States and North Korea.
• What factors contributed to the current decline in the rate of unemployment?
• What have been the impacts of states which have increased their minimum wage?
• How do US immigration laws compare to immigration laws of other countries?
• How have the US's immigration laws changed in the past few years/decades?
• How has the Black Lives Matter movement affected discussions and view about racism in the US?
• What impact has the Affordable Care Act had on healthcare in the US?
• What factors contributed to the UK deciding to leave the EU (Brexit)?
• What factors contributed to China becoming an economic power?
• Discuss the history of Bitcoin or other cryptocurrencies  (some of which tokenize the S&P 500 Index on the blockchain) .
• Do students in schools that eliminate grades do better in college and their careers?
• Do students from wealthier backgrounds score higher on standardized tests?
• Do students who receive free meals at school get higher grades compared to when they weren't receiving a free meal?
• Do students who attend charter schools score higher on standardized tests than students in public schools?
• Do students learn better in same-sex classrooms?
• How does giving each student access to an iPad or laptop affect their studies?
• What are the benefits and drawbacks of the Montessori Method ?
• Do children who attend preschool do better in school later on?
• What was the impact of the No Child Left Behind act?
• How does the US education system compare to education systems in other countries?
• What impact does mandatory physical education classes have on students' health?
• Which methods are most effective at reducing bullying in schools?
• Do homeschoolers who attend college do as well as students who attended traditional schools?
• Does offering tenure increase or decrease quality of teaching?
• How does college debt affect future life choices of students?
• Should graduate students be able to form unions?

• What are different ways to lower gun-related deaths in the US?
• How and why have divorce rates changed over time?
• Is affirmative action still necessary in education and/or the workplace?
• Should physician-assisted suicide be legal?
• How has stem cell research impacted the medical field?
• How can human trafficking be reduced in the United States/world?
• Should people be able to donate organs in exchange for money?
• Which types of juvenile punishment have proven most effective at preventing future crimes?
• Has the increase in US airport security made passengers safer?
• Analyze the immigration policies of certain countries and how they are similar and different from one another.
• Several states have legalized recreational marijuana. What positive and negative impacts have they experienced as a result?
• Do tariffs increase the number of domestic jobs?
• Which prison reforms have proven most effective?
• Should governments be able to censor certain information on the internet?
• Which methods/programs have been most effective at reducing teen pregnancy?
• What are the benefits and drawbacks of the Keto diet?
• How effective are different exercise regimes for losing weight and maintaining weight loss?
• How do the healthcare plans of various countries differ from each other?
• What are the most effective ways to treat depression ?
• What are the pros and cons of genetically modified foods?
• Which methods are most effective for improving memory?
• What can be done to lower healthcare costs in the US?
• What factors contributed to the current opioid crisis?
• Analyze the history and impact of the HIV/AIDS epidemic .
• Are low-carbohydrate or low-fat diets more effective for weight loss?
• How much exercise should the average adult be getting each week?
• Which methods are most effective to get parents to vaccinate their children?
• What are the pros and cons of clean needle programs?
• How does stress affect the body?
• Discuss the history of the conflict between Israel and the Palestinians.
• What were the causes and effects of the Salem Witch Trials?
• Who was responsible for the Iran-Contra situation?
• How has New Orleans and the government's response to natural disasters changed since Hurricane Katrina?
• What events led to the fall of the Roman Empire?
• What were the impacts of British rule in India ?
• Was the atomic bombing of Hiroshima and Nagasaki necessary?
• What were the successes and failures of the women's suffrage movement in the United States?
• What were the causes of the Civil War?
• How did Abraham Lincoln's assassination impact the country and reconstruction after the Civil War?
• Which factors contributed to the colonies winning the American Revolution?
• What caused Hitler's rise to power?
• Discuss how a specific invention impacted history.
• What led to Cleopatra's fall as ruler of Egypt?
• How has Japan changed and evolved over the centuries?
• What were the causes of the Rwandan genocide ?

• Why did Martin Luther decide to split with the Catholic Church?
• Analyze the history and impact of a well-known cult (Jonestown, Manson family, etc.)
• How did the sexual abuse scandal impact how people view the Catholic Church?
• How has the Catholic church's power changed over the past decades/centuries?
• What are the causes behind the rise in atheism/ agnosticism in the United States?
• What were the influences in Siddhartha's life resulted in him becoming the Buddha?
• How has media portrayal of Islam/Muslims changed since September 11th?

Science/Environment

• How has the earth's climate changed in the past few decades?
• How has the use and elimination of DDT affected bird populations in the US?
• Analyze how the number and severity of natural disasters have increased in the past few decades.
• Analyze deforestation rates in a certain area or globally over a period of time.
• How have past oil spills changed regulations and cleanup methods?
• How has the Flint water crisis changed water regulation safety?
• What are the pros and cons of fracking?
• What impact has the Paris Climate Agreement had so far?
• What have NASA's biggest successes and failures been?
• How can we improve access to clean water around the world?
• Does ecotourism actually have a positive impact on the environment?
• Should the US rely on nuclear energy more?
• What can be done to save amphibian species currently at risk of extinction?
• What impact has climate change had on coral reefs?
• How are black holes created?
• Are teens who spend more time on social media more likely to suffer anxiety and/or depression?
• How will the loss of net neutrality affect internet users?
• Analyze the history and progress of self-driving vehicles.
• How has the use of drones changed surveillance and warfare methods?
• Has social media made people more or less connected?
• What progress has currently been made with artificial intelligence ?
• Do smartphones increase or decrease workplace productivity?
• What are the most effective ways to use technology in the classroom?
• How is Google search affecting our intelligence?
• When is the best age for a child to begin owning a smartphone?
• Has frequent texting reduced teen literacy rates?

How to Write a Great Research Paper

Even great research paper topics won't give you a great research paper if you don't hone your topic before and during the writing process. Follow these three tips to turn good research paper topics into great papers.

#1: Figure Out Your Thesis Early

Before you start writing a single word of your paper, you first need to know what your thesis will be. Your thesis is a statement that explains what you intend to prove/show in your paper. Every sentence in your research paper will relate back to your thesis, so you don't want to start writing without it!

As some examples, if you're writing a research paper on if students learn better in same-sex classrooms, your thesis might be "Research has shown that elementary-age students in same-sex classrooms score higher on standardized tests and report feeling more comfortable in the classroom."

If you're writing a paper on the causes of the Civil War, your thesis might be "While the dispute between the North and South over slavery is the most well-known cause of the Civil War, other key causes include differences in the economies of the North and South, states' rights, and territorial expansion."

#2: Back Every Statement Up With Research

Remember, this is a research paper you're writing, so you'll need to use lots of research to make your points. Every statement you give must be backed up with research, properly cited the way your teacher requested. You're allowed to include opinions of your own, but they must also be supported by the research you give.

#3: Do Your Research Before You Begin Writing

You don't want to start writing your research paper and then learn that there isn't enough research to back up the points you're making, or, even worse, that the research contradicts the points you're trying to make!

Get most of your research on your good research topics done before you begin writing. Then use the research you've collected to create a rough outline of what your paper will cover and the key points you're going to make. This will help keep your paper clear and organized, and it'll ensure you have enough research to produce a strong paper.

What's Next?

Are you also learning about dynamic equilibrium in your science class? We break this sometimes tricky concept down so it's easy to understand in our complete guide to dynamic equilibrium .

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These recommendations are based solely on our knowledge and experience. If you purchase an item through one of our links, PrepScholar may receive a commission.

Christine graduated from Michigan State University with degrees in Environmental Biology and Geography and received her Master's from Duke University. In high school she scored in the 99th percentile on the SAT and was named a National Merit Finalist. She has taught English and biology in several countries.

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​120 Questions to Ask a Scientist

Diving into the wonders of science can be an extraordinary journey, and there’s no shortage of fascinating topics to explore. Through these carefully crafted questions to ask a scientist, this article serves as your gateway to understanding the marvels of science in a simple, relatable way.

Whether you’re casually curious, a student of the sciences, or prepping for an insightful conversation, these queries are your keys to unlocking the knowledge and passion of the experts who are shaping our world.

Table of Contents

General Scientific Inquiry

• What sparked your interest in science initially?
• How do you formulate a research question?
• What’s the most surprising scientific discovery you’ve encountered in recent years?
• In layman’s terms, can you explain your current research focus?
• How does the scientific method guide your daily research?
• What’s the most common misconception about your field?
• How do you determine the validity of your scientific findings?
• Can you share an example of a serendipitous discovery in your career?
• What’s a day in the life of a scientist like for you?
• How do you stay updated with the latest scientific advancements?
• What role does collaboration play in your scientific research?
• How does one go about publishing a scientific paper?
• What’s the most challenging aspect of conducting experiments?
• How important is peer review in your field of study?
• What has been the most rewarding outcome of your research?

Career and Personal Journey in Science

• What inspired you to become a scientist?
• Could you share some highlights of your career so far?
• What challenges have you faced in your scientific career, and how did you overcome them?
• What advice would you give to someone starting their science career?
• Can you describe a pivotal moment in your scientific journey?
• How has your field of study evolved since you began your career?
• What educational path did you take to reach your current position?
• How do you balance work and personal life as a scientist?
• Can you share a moment of failure in your career and what you learned from it?
• What advancements do you hope to see in your field in the next decade?
• What skills do you believe are essential for a successful career in science?
• Has there been a mentor who significantly influenced your professional path?
• How do you define success in your career?
• What’s the best career advice you’ve ever received?
• How do you navigate the competitive nature of the scientific community?

Current Research and Future Projects

• What is the focus of your current research project?
• How could your current research change the way we understand the world?
• What breakthroughs in your field might we see in the near future?
• How do you plan your research projects?
• What technology plays a pivotal role in your current research?
• Could you give us a brief overview of the scientific process behind your latest project?
• How do you secure funding for your research?
• What are some unintended consequences you must consider in your current research?
• How do you ensure the ethical integrity of your research?
• What is the potential societal impact of your current projects?
• What collaborations are you currently involved in?
• Are there any policy implications of your current research?
• How do you measure the success of a research project?
• What has been the most surprising finding in your current research?
• Are there any upcoming scientific conferences where you’ll be presenting your work?

The Impact of Science on Society

• How does your research contribute to society?
• What’s the role of science in addressing global challenges?
• How can scientific research drive policy change?
• Can you provide an example of a scientific discovery that significantly improved lives?
• What can the general public do to support scientific research?
• How does science influence everyday decision-making?
• What ethical responsibilities do scientists have toward society?
• In what ways does science education benefit society as a whole?
• How can we bridge the gap between scientific communities and the public?
• What’s the importance of science communication in today’s world?
• How do you see the relationship between technology and society evolving?
• Can you discuss the science behind a current event that’s impacting society?
• In what ways can scientists be more involved in community outreach?
• How can we use science to foster sustainability and environmental responsibility?
• What are the potential risks of not considering the societal impact of scientific research?

Advice for Aspiring Scientists

• What qualities do you think are important for a budding scientist?
• How can students best prepare for a career in science?
• What courses or experiences do you recommend for young scientists?
• Can you suggest any essential readings or resources for those interested in science?
• How important is interdisciplinary knowledge in science?
• What advice do you have for maintaining persistence in challenging research tasks?
• How can aspiring scientists gain practical experience in their field of interest?
• What steps should students take to pursue a career in your specific field of science?
• How does one develop a robust scientific hypothesis?
• What is the role of mentorship in developing a scientific career?
• Can you describe the importance of critical thinking in science?
• How should young scientists approach networking within their field?
• What are some common pitfalls to avoid in a scientific career?
• How can aspiring scientists contribute to innovation?
• What motivational insights can you share with someone considering a science degree?

Ethical Considerations in Science

• How do you approach ethical dilemmas in your research?
• What are some current ethical debates in your field?
• How does informed consent play a role in your studies?
• Can you discuss the ethical implications of data privacy in research?
• How do you ensure the humane treatment of animals in your research?
• What checks and balances exist to ensure ethical standards in science?
• Can you talk about a time when you had to weigh the risks and benefits of a study?
• How has the landscape of scientific ethics changed during your career?
• What is the role of ethics committees in scientific research?
• How should scientists balance progress with the potential ethical consequences?
• What are your thoughts on the use of CRISPR technology and gene editing?
• How can the scientific community better educate the public on ethical issues in science?
• What is your opinion on patenting scientific discoveries?
• How do ethical considerations vary internationally in science?
• What steps do you take to address cultural sensitivities in your research?

Science in Daily Life and Popular Culture

• How does your field of research relate to everyday life?
• Can you provide an example of how science influences our daily decisions?
• What’s a common scientific myth you’d like to debunk?
• How do you think science fiction influences public perception of science?
• Can you discuss a recent scientific discovery featured in the media?
• How has pop culture misrepresented your field of science?
• What role does science play in your personal day-to-day life?
• How do you engage with science in your leisure time?
• What impact does social media have on the public’s understanding of science?
• How can scientific knowledge be more accessible to non-scientists?
• What do you wish more people knew about the scientific process?
• How do you see art and science intersecting?
• How can we make scientific topics more appealing in the education system?
• What are some science-based apps or tools that you use regularly?
• Can you recommend any scientific documentaries or series that accurately portray your field?

Understanding Complex Scientific Concepts

• Can you simplify the concept of quantum mechanics for a lay audience?
• How would you explain the significance of the theory of relativity in everyday terms?
• What are the most important things to understand about climate change?
• How can complex biological systems be broken down for general understanding?
• Could you outline the steps of the scientific process in basic language?
• How do you approach explaining your research to people without a scientific background?
• What are some strategies for learning difficult scientific theories?
• Can you clarify what “ dark matter ” means in astronomy?
• How do genes impact our lives beyond just inheritance?
• What misconceptions do people often have about vaccines, and how would you address them?
• How can someone without a scientific background understand significant health studies?
• In what ways can the public misunderstand statistical data?
• Can you explain how new technologies are shaping scientific discoveries in your field?
• What is the importance of biodiversity, and how does it affect our ecosystem?
• How does the placebo effect work, and why is it important in medical research?

Frequently Asked Questions

What are the benefits of understanding scientific concepts.

Understanding scientific concepts can  improve critical thinking, inform decision-making , and help us appreciate how the world around us operates. It also enables us to engage in informed discussions about science-related policies and societal changes.

How can I respectfully challenge a scientist’s viewpoint?

If you wish to challenge a scientist’s viewpoint, ensure it’s done with respect and evidence-based reasoning. Approach the conversation with an  open mind and a willingness to understand their perspective  while presenting your own questions or concerns.

Final Thoughts

Venturing into the depths of scientific exploration can be a thrilling experience. Our conversation with a scientist does not have to be daunting; rather, it can be a bridge connecting the curious mind with the complex world of science.

The questions I’ve listed offer a starting point for dialogue, opening doors to understanding not just the ‘what’ and ‘how’ but also the ‘ who ‘ behind scientific progress. Remember, every big discovery begins with a question, so never hesitate to ask.

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Bea Mariel Saulo

Science Bob

• Experiments
• Science Fair Ideas
• Science Q&A
• Research Help
• Experiment Blog

Okay, this is the hardest part of the whole project…picking your topic. But here are some ideas to get you started. Even if you don’t like any, they may inspire you to come up with one of your own. Remember, check all project ideas with your teacher and parents, and don’t do any project that would hurt or scare people or animals. Good luck!

• Does music affect on animal behavior?
• Does the color of food or drinks affect whether or not we like them?
• Where are the most germs in your school? ( CLICK for more info. )
• Does music have an affect on plant growth?
• Which kind of food do dogs (or any animal) prefer best?
• Which paper towel brand is the strongest?
• What is the best way to keep an ice cube from melting?
• What level of salt works best to hatch brine shrimp?
• Can the food we eat affect our heart rate?
• How effective are child-proof containers and locks.
• Can background noise levels affect how well we concentrate?
• Does acid rain affect the growth of aquatic plants?
• What is the best way to keep cut flowers fresh the longest?
• Does the color of light used on plants affect how well they grow?
• What plant fertilizer works best?
• Does the color of a room affect human behavior?
• Do athletic students have better lung capacity?
• What brand of battery lasts the longest?
• Does the type of potting soil used in planting affect how fast the plant grows?
• What type of food allow mold to grow the fastest?
• Does having worms in soil help plants grow faster?
• Can plants grow in pots if they are sideways or upside down?
• Does the color of hair affect how much static electricity it can carry? (test with balloons)
• How much weight can the surface tension of water hold?
• Can some people really read someone else’s thoughts?
• Which soda decays fallen out teeth the most?
• What light brightness makes plants grow the best?
• Does the color of birdseed affect how much birds will eat it?
• Do natural or chemical fertilizers work best?
• Can mice learn? (you can pick any animal)
• Can people tell artificial smells from real ones?
• What brands of bubble gum produce the biggest bubbles?
• Does age affect human reaction times?
• What is the effect of salt on the boiling temperature of water?
• Does shoe design really affect an athlete’s jumping height?
• What type of grass seed grows the fastest?
• Can animals see in the dark better than humans?

Didn’t see one you like? Don’t worry…look over them again and see if they give you an idea for your own project that will work for you. Remember, find something that interests you, and have fun with it.

To download and print this list of ideas CLICK HERE .

• The scientific method
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Writing Survey Questions

Perhaps the most important part of the survey process is the creation of questions that accurately measure the opinions, experiences and behaviors of the public. Accurate random sampling will be wasted if the information gathered is built on a shaky foundation of ambiguous or biased questions. Creating good measures involves both writing good questions and organizing them to form the questionnaire.

Questionnaire design is a multistage process that requires attention to many details at once. Designing the questionnaire is complicated because surveys can ask about topics in varying degrees of detail, questions can be asked in different ways, and questions asked earlier in a survey may influence how people respond to later questions. Researchers are also often interested in measuring change over time and therefore must be attentive to how opinions or behaviors have been measured in prior surveys.

Surveyors may conduct pilot tests or focus groups in the early stages of questionnaire development in order to better understand how people think about an issue or comprehend a question. Pretesting a survey is an essential step in the questionnaire design process to evaluate how people respond to the overall questionnaire and specific questions, especially when questions are being introduced for the first time.

For many years, surveyors approached questionnaire design as an art, but substantial research over the past forty years has demonstrated that there is a lot of science involved in crafting a good survey questionnaire. Here, we discuss the pitfalls and best practices of designing questionnaires.

Question development

There are several steps involved in developing a survey questionnaire. The first is identifying what topics will be covered in the survey. For Pew Research Center surveys, this involves thinking about what is happening in our nation and the world and what will be relevant to the public, policymakers and the media. We also track opinion on a variety of issues over time so we often ensure that we update these trends on a regular basis to better understand whether people’s opinions are changing.

At Pew Research Center, questionnaire development is a collaborative and iterative process where staff meet to discuss drafts of the questionnaire several times over the course of its development. We frequently test new survey questions ahead of time through qualitative research methods such as  focus groups , cognitive interviews, pretesting (often using an  online, opt-in sample ), or a combination of these approaches. Researchers use insights from this testing to refine questions before they are asked in a production survey, such as on the ATP.

Measuring change over time

Many surveyors want to track changes over time in people’s attitudes, opinions and behaviors. To measure change, questions are asked at two or more points in time. A cross-sectional design surveys different people in the same population at multiple points in time. A panel, such as the ATP, surveys the same people over time. However, it is common for the set of people in survey panels to change over time as new panelists are added and some prior panelists drop out. Many of the questions in Pew Research Center surveys have been asked in prior polls. Asking the same questions at different points in time allows us to report on changes in the overall views of the general public (or a subset of the public, such as registered voters, men or Black Americans), or what we call “trending the data”.

When measuring change over time, it is important to use the same question wording and to be sensitive to where the question is asked in the questionnaire to maintain a similar context as when the question was asked previously (see  question wording  and  question order  for further information). All of our survey reports include a topline questionnaire that provides the exact question wording and sequencing, along with results from the current survey and previous surveys in which we asked the question.

The Center’s transition from conducting U.S. surveys by live telephone interviewing to an online panel (around 2014 to 2020) complicated some opinion trends, but not others. Opinion trends that ask about sensitive topics (e.g., personal finances or attending religious services ) or that elicited volunteered answers (e.g., “neither” or “don’t know”) over the phone tended to show larger differences than other trends when shifting from phone polls to the online ATP. The Center adopted several strategies for coping with changes to data trends that may be related to this change in methodology. If there is evidence suggesting that a change in a trend stems from switching from phone to online measurement, Center reports flag that possibility for readers to try to head off confusion or erroneous conclusions.

Open- and closed-ended questions

One of the most significant decisions that can affect how people answer questions is whether the question is posed as an open-ended question, where respondents provide a response in their own words, or a closed-ended question, where they are asked to choose from a list of answer choices.

For example, in a poll conducted after the 2008 presidential election, people responded very differently to two versions of the question: “What one issue mattered most to you in deciding how you voted for president?” One was closed-ended and the other open-ended. In the closed-ended version, respondents were provided five options and could volunteer an option not on the list.

When explicitly offered the economy as a response, more than half of respondents (58%) chose this answer; only 35% of those who responded to the open-ended version volunteered the economy. Moreover, among those asked the closed-ended version, fewer than one-in-ten (8%) provided a response other than the five they were read. By contrast, fully 43% of those asked the open-ended version provided a response not listed in the closed-ended version of the question. All of the other issues were chosen at least slightly more often when explicitly offered in the closed-ended version than in the open-ended version. (Also see  “High Marks for the Campaign, a High Bar for Obama”  for more information.)

Researchers will sometimes conduct a pilot study using open-ended questions to discover which answers are most common. They will then develop closed-ended questions based off that pilot study that include the most common responses as answer choices. In this way, the questions may better reflect what the public is thinking, how they view a particular issue, or bring certain issues to light that the researchers may not have been aware of.

When asking closed-ended questions, the choice of options provided, how each option is described, the number of response options offered, and the order in which options are read can all influence how people respond. One example of the impact of how categories are defined can be found in a Pew Research Center poll conducted in January 2002. When half of the sample was asked whether it was “more important for President Bush to focus on domestic policy or foreign policy,” 52% chose domestic policy while only 34% said foreign policy. When the category “foreign policy” was narrowed to a specific aspect – “the war on terrorism” – far more people chose it; only 33% chose domestic policy while 52% chose the war on terrorism.

In most circumstances, the number of answer choices should be kept to a relatively small number – just four or perhaps five at most – especially in telephone surveys. Psychological research indicates that people have a hard time keeping more than this number of choices in mind at one time. When the question is asking about an objective fact and/or demographics, such as the religious affiliation of the respondent, more categories can be used. In fact, they are encouraged to ensure inclusivity. For example, Pew Research Center’s standard religion questions include more than 12 different categories, beginning with the most common affiliations (Protestant and Catholic). Most respondents have no trouble with this question because they can expect to see their religious group within that list in a self-administered survey.

In addition to the number and choice of response options offered, the order of answer categories can influence how people respond to closed-ended questions. Research suggests that in telephone surveys respondents more frequently choose items heard later in a list (a “recency effect”), and in self-administered surveys, they tend to choose items at the top of the list (a “primacy” effect).

Because of concerns about the effects of category order on responses to closed-ended questions, many sets of response options in Pew Research Center’s surveys are programmed to be randomized to ensure that the options are not asked in the same order for each respondent. Rotating or randomizing means that questions or items in a list are not asked in the same order to each respondent. Answers to questions are sometimes affected by questions that precede them. By presenting questions in a different order to each respondent, we ensure that each question gets asked in the same context as every other question the same number of times (e.g., first, last or any position in between). This does not eliminate the potential impact of previous questions on the current question, but it does ensure that this bias is spread randomly across all of the questions or items in the list. For instance, in the example discussed above about what issue mattered most in people’s vote, the order of the five issues in the closed-ended version of the question was randomized so that no one issue appeared early or late in the list for all respondents. Randomization of response items does not eliminate order effects, but it does ensure that this type of bias is spread randomly.

Questions with ordinal response categories – those with an underlying order (e.g., excellent, good, only fair, poor OR very favorable, mostly favorable, mostly unfavorable, very unfavorable) – are generally not randomized because the order of the categories conveys important information to help respondents answer the question. Generally, these types of scales should be presented in order so respondents can easily place their responses along the continuum, but the order can be reversed for some respondents. For example, in one of Pew Research Center’s questions about abortion, half of the sample is asked whether abortion should be “legal in all cases, legal in most cases, illegal in most cases, illegal in all cases,” while the other half of the sample is asked the same question with the response categories read in reverse order, starting with “illegal in all cases.” Again, reversing the order does not eliminate the recency effect but distributes it randomly across the population.

Question wording

The choice of words and phrases in a question is critical in expressing the meaning and intent of the question to the respondent and ensuring that all respondents interpret the question the same way. Even small wording differences can substantially affect the answers people provide.

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An example of a wording difference that had a significant impact on responses comes from a January 2003 Pew Research Center survey. When people were asked whether they would “favor or oppose taking military action in Iraq to end Saddam Hussein’s rule,” 68% said they favored military action while 25% said they opposed military action. However, when asked whether they would “favor or oppose taking military action in Iraq to end Saddam Hussein’s rule  even if it meant that U.S. forces might suffer thousands of casualties, ” responses were dramatically different; only 43% said they favored military action, while 48% said they opposed it. The introduction of U.S. casualties altered the context of the question and influenced whether people favored or opposed military action in Iraq.

There has been a substantial amount of research to gauge the impact of different ways of asking questions and how to minimize differences in the way respondents interpret what is being asked. The issues related to question wording are more numerous than can be treated adequately in this short space, but below are a few of the important things to consider:

First, it is important to ask questions that are clear and specific and that each respondent will be able to answer. If a question is open-ended, it should be evident to respondents that they can answer in their own words and what type of response they should provide (an issue or problem, a month, number of days, etc.). Closed-ended questions should include all reasonable responses (i.e., the list of options is exhaustive) and the response categories should not overlap (i.e., response options should be mutually exclusive). Further, it is important to discern when it is best to use forced-choice close-ended questions (often denoted with a radio button in online surveys) versus “select-all-that-apply” lists (or check-all boxes). A 2019 Center study found that forced-choice questions tend to yield more accurate responses, especially for sensitive questions.  Based on that research, the Center generally avoids using select-all-that-apply questions.

It is also important to ask only one question at a time. Questions that ask respondents to evaluate more than one concept (known as double-barreled questions) – such as “How much confidence do you have in President Obama to handle domestic and foreign policy?” – are difficult for respondents to answer and often lead to responses that are difficult to interpret. In this example, it would be more effective to ask two separate questions, one about domestic policy and another about foreign policy.

In general, questions that use simple and concrete language are more easily understood by respondents. It is especially important to consider the education level of the survey population when thinking about how easy it will be for respondents to interpret and answer a question. Double negatives (e.g., do you favor or oppose  not  allowing gays and lesbians to legally marry) or unfamiliar abbreviations or jargon (e.g., ANWR instead of Arctic National Wildlife Refuge) can result in respondent confusion and should be avoided.

Similarly, it is important to consider whether certain words may be viewed as biased or potentially offensive to some respondents, as well as the emotional reaction that some words may provoke. For example, in a 2005 Pew Research Center survey, 51% of respondents said they favored “making it legal for doctors to give terminally ill patients the means to end their lives,” but only 44% said they favored “making it legal for doctors to assist terminally ill patients in committing suicide.” Although both versions of the question are asking about the same thing, the reaction of respondents was different. In another example, respondents have reacted differently to questions using the word “welfare” as opposed to the more generic “assistance to the poor.” Several experiments have shown that there is much greater public support for expanding “assistance to the poor” than for expanding “welfare.”

We often write two versions of a question and ask half of the survey sample one version of the question and the other half the second version. Thus, we say we have two  forms  of the questionnaire. Respondents are assigned randomly to receive either form, so we can assume that the two groups of respondents are essentially identical. On questions where two versions are used, significant differences in the answers between the two forms tell us that the difference is a result of the way we worded the two versions.

One of the most common formats used in survey questions is the “agree-disagree” format. In this type of question, respondents are asked whether they agree or disagree with a particular statement. Research has shown that, compared with the better educated and better informed, less educated and less informed respondents have a greater tendency to agree with such statements. This is sometimes called an “acquiescence bias” (since some kinds of respondents are more likely to acquiesce to the assertion than are others). This behavior is even more pronounced when there’s an interviewer present, rather than when the survey is self-administered. A better practice is to offer respondents a choice between alternative statements. A Pew Research Center experiment with one of its routinely asked values questions illustrates the difference that question format can make. Not only does the forced choice format yield a very different result overall from the agree-disagree format, but the pattern of answers between respondents with more or less formal education also tends to be very different.

One other challenge in developing questionnaires is what is called “social desirability bias.” People have a natural tendency to want to be accepted and liked, and this may lead people to provide inaccurate answers to questions that deal with sensitive subjects. Research has shown that respondents understate alcohol and drug use, tax evasion and racial bias. They also may overstate church attendance, charitable contributions and the likelihood that they will vote in an election. Researchers attempt to account for this potential bias in crafting questions about these topics. For instance, when Pew Research Center surveys ask about past voting behavior, it is important to note that circumstances may have prevented the respondent from voting: “In the 2012 presidential election between Barack Obama and Mitt Romney, did things come up that kept you from voting, or did you happen to vote?” The choice of response options can also make it easier for people to be honest. For example, a question about church attendance might include three of six response options that indicate infrequent attendance. Research has also shown that social desirability bias can be greater when an interviewer is present (e.g., telephone and face-to-face surveys) than when respondents complete the survey themselves (e.g., paper and web surveys).

Lastly, because slight modifications in question wording can affect responses, identical question wording should be used when the intention is to compare results to those from earlier surveys. Similarly, because question wording and responses can vary based on the mode used to survey respondents, researchers should carefully evaluate the likely effects on trend measurements if a different survey mode will be used to assess change in opinion over time.

Question order

Once the survey questions are developed, particular attention should be paid to how they are ordered in the questionnaire. Surveyors must be attentive to how questions early in a questionnaire may have unintended effects on how respondents answer subsequent questions. Researchers have demonstrated that the order in which questions are asked can influence how people respond; earlier questions can unintentionally provide context for the questions that follow (these effects are called “order effects”).

One kind of order effect can be seen in responses to open-ended questions. Pew Research Center surveys generally ask open-ended questions about national problems, opinions about leaders and similar topics near the beginning of the questionnaire. If closed-ended questions that relate to the topic are placed before the open-ended question, respondents are much more likely to mention concepts or considerations raised in those earlier questions when responding to the open-ended question.

For closed-ended opinion questions, there are two main types of order effects: contrast effects ( where the order results in greater differences in responses), and assimilation effects (where responses are more similar as a result of their order).

An example of a contrast effect can be seen in a Pew Research Center poll conducted in October 2003, a dozen years before same-sex marriage was legalized in the U.S. That poll found that people were more likely to favor allowing gays and lesbians to enter into legal agreements that give them the same rights as married couples when this question was asked after one about whether they favored or opposed allowing gays and lesbians to marry (45% favored legal agreements when asked after the marriage question, but 37% favored legal agreements without the immediate preceding context of a question about same-sex marriage). Responses to the question about same-sex marriage, meanwhile, were not significantly affected by its placement before or after the legal agreements question.

Another experiment embedded in a December 2008 Pew Research Center poll also resulted in a contrast effect. When people were asked “All in all, are you satisfied or dissatisfied with the way things are going in this country today?” immediately after having been asked “Do you approve or disapprove of the way George W. Bush is handling his job as president?”; 88% said they were dissatisfied, compared with only 78% without the context of the prior question.

Responses to presidential approval remained relatively unchanged whether national satisfaction was asked before or after it. A similar finding occurred in December 2004 when both satisfaction and presidential approval were much higher (57% were dissatisfied when Bush approval was asked first vs. 51% when general satisfaction was asked first).

Several studies also have shown that asking a more specific question before a more general question (e.g., asking about happiness with one’s marriage before asking about one’s overall happiness) can result in a contrast effect. Although some exceptions have been found, people tend to avoid redundancy by excluding the more specific question from the general rating.

Assimilation effects occur when responses to two questions are more consistent or closer together because of their placement in the questionnaire. We found an example of an assimilation effect in a Pew Research Center poll conducted in November 2008 when we asked whether Republican leaders should work with Obama or stand up to him on important issues and whether Democratic leaders should work with Republican leaders or stand up to them on important issues. People were more likely to say that Republican leaders should work with Obama when the question was preceded by the one asking what Democratic leaders should do in working with Republican leaders (81% vs. 66%). However, when people were first asked about Republican leaders working with Obama, fewer said that Democratic leaders should work with Republican leaders (71% vs. 82%).

The order questions are asked is of particular importance when tracking trends over time. As a result, care should be taken to ensure that the context is similar each time a question is asked. Modifying the context of the question could call into question any observed changes over time (see  measuring change over time  for more information).

A questionnaire, like a conversation, should be grouped by topic and unfold in a logical order. It is often helpful to begin the survey with simple questions that respondents will find interesting and engaging. Throughout the survey, an effort should be made to keep the survey interesting and not overburden respondents with several difficult questions right after one another. Demographic questions such as income, education or age should not be asked near the beginning of a survey unless they are needed to determine eligibility for the survey or for routing respondents through particular sections of the questionnaire. Even then, it is best to precede such items with more interesting and engaging questions. One virtue of survey panels like the ATP is that demographic questions usually only need to be asked once a year, not in each survey.

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Ethical care for research animals

WHY ANIMAL RESEARCH?

The use of animals in some forms of biomedical research remains essential to the discovery of the causes, diagnoses, and treatment of disease and suffering in humans and in animals., stanford shares the public's concern for laboratory research animals..

Many people have questions about animal testing ethics and the animal testing debate. We take our responsibility for the ethical treatment of animals in medical research very seriously. At Stanford, we emphasize that the humane care of laboratory animals is essential, both ethically and scientifically.  Poor animal care is not good science. If animals are not well-treated, the science and knowledge they produce is not trustworthy and cannot be replicated, an important hallmark of the scientific method .

There are several reasons why the use of animals is critical for biomedical research: 

••  Animals are biologically very similar to humans. In fact, mice share more than 98% DNA with us!

••  Animals are susceptible to many of the same health problems as humans – cancer, diabetes, heart disease, etc.

••  With a shorter life cycle than humans, animal models can be studied throughout their whole life span and across several generations, a critical element in understanding how a disease processes and how it interacts with a whole, living biological system.

The ethics of animal experimentation

Nothing so far has been discovered that can be a substitute for the complex functions of a living, breathing, whole-organ system with pulmonary and circulatory structures like those in humans. Until such a discovery, animals must continue to play a critical role in helping researchers test potential new drugs and medical treatments for effectiveness and safety, and in identifying any undesired or dangerous side effects, such as infertility, birth defects, liver damage, toxicity, or cancer-causing potential.

U.S. federal laws require that non-human animal research occur to show the safety and efficacy of new treatments before any human research will be allowed to be conducted.  Not only do we humans benefit from this research and testing, but hundreds of drugs and treatments developed for human use are now routinely used in veterinary clinics as well, helping animals live longer, healthier lives.

It is important to stress that 95% of all animals necessary for biomedical research in the United States are rodents – rats and mice especially bred for laboratory use – and that animals are only one part of the larger process of biomedical research.

Our researchers are strong supporters of animal welfare and view their work with animals in biomedical research as a privilege.

Stanford researchers are obligated to ensure the well-being of all animals in their care..

Stanford researchers are obligated to ensure the well-being of animals in their care, in strict adherence to the highest standards, and in accordance with federal and state laws, regulatory guidelines, and humane principles. They are also obligated to continuously update their animal-care practices based on the newest information and findings in the fields of laboratory animal care and husbandry.  

Researchers requesting use of animal models at Stanford must have their research proposals reviewed by a federally mandated committee that includes two independent community members.  It is only with this committee’s approval that research can begin. We at Stanford are dedicated to refining, reducing, and replacing animals in research whenever possible, and to using alternative methods (cell and tissue cultures, computer simulations, etc.) instead of or before animal studies are ever conducted.

Organizations and Resources

There are many outreach and advocacy organizations in the field of biomedical research.

• Learn more about outreach and advocacy organizations

Stanford Discoveries

What are the benefits of using animals in research? Stanford researchers have made many important human and animal life-saving discoveries through their work. 

• Learn more about research discoveries at Stanford

The science of happiness

First-year students hone more than their research skills by exploring what it means to be happy

What is happiness, and why do we strive for it? Can we become happier? Should we? Is happiness a good thing? 

Dr. Megan McCarthy (PhD ’16)

“ARTS 140 is really focused on becoming critical consumers of information and learning how to organize evidence to make a compelling argument,” McCarthy said.  

McCarthy designed the course to challenge students to think about their beliefs and understanding of happiness, research and test various perspectives on happiness and critically evaluate claims about it.   

But can students — or anyone — separate their personal and intuitive feelings about happiness to examine it critically?  

“I first ask the students to try to write their own definition of happiness,” McCarthy said. “And then they look at different definitions over different eras, fields and in different parts of the world. I get them to reflect on how their definition compares to other conceptions. And then we talk about the roles of empiricism, critical thinking and how looking at data can shape our understanding.”  

Having taught the course every term since 2021, McCarthy has found that, because students often come from different backgrounds, they engage in rich comparative discussions with classmates about their own beliefs and how their experiences led to those beliefs. Through these interactions, the students become “much more accepting of different ways of looking at the subject because they're exposed to different experiences. And they have a lot of fun.”  

I've had students talk to me about how the course has transformed their personal lives. — DR. MEGAN MCCARTHY  (PhD ’16)

As a practice-based course, the students are encouraged to test happiness-boosting claims and then reflect, discuss and evaluate them. In their main project, they even developed their own methods to increase happiness in the community, drawing from their primary research sources and interpretation of evidence.   

Student happiness projects included cooking dinner with their family to increase bonding, making and delivering care packages for unhoused people in the area and organizing a sharing circle in their university residence to reduce stress and enhance social connections.  

One student designed a happiness plan for their workplace after noticing employees weren’t working effectively as a team. They developed a method to strengthen the co-worker community and improve well-being. The student reported that their manager was planning to implement the changes in the workplace in the future.   

“I've had students tell me that the assignments have made them fall in love with research,” McCarthy said. “They get really excited about the process — how to come up with a research question, collect the data and think critically about it.”   

McCarthy sets specific learning outcomes for the course, which include being able to reflect critically on their own cultural experiences that shape how they feel. “I think that one is important because that can be applied across disciplines where they're learning to engage with the ideas and beliefs of others and understand their own assumptions. And I think that can support good relationships and community.”   

Becoming a better researcher is not the only positive outcome of the course. “I hear about it impacting emotional or social well-being,” McCarthy reflected. “I've had students talk to me about how the course has transformed their personal lives. That it has made them happier people, that it has made them think differently about the way they're engaging with and relating to other people. And that's tremendously powerful for me.”  

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