journal of chemical and pharmaceutical research

Pharmaceutical Research

An Official Journal of the American Association of Pharmaceutical Scientists

• Publishes papers on small drug molecules, biotechnology products including genes, peptides, proteins, vaccines, and genetically engineered cells.
• Known for excellent author service with 97% of authors expressing interest to publish again.
• Publishes twelve issues a year.

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Latest issue

Volume 41, Issue 3

Latest articles

Identification of surfactant impact on a monoclonal antibody characterization via hplc-separation based and biophysical methods.

• Rico C. Gunawan

Predicting Drug-Drug Interactions Involving Rifampicin Using a Semi-mechanistic Hepatic Compartmental Model

Pharmacokinetic Profile of Brepocitinib with Topical Administration in Atopic Dermatitis and Psoriasis Populations: Strategy to Inform Clinical Trial Design in Adult and Pediatric Populations

• Farzaneh Maleki
• Cheng Chang
• Timothy Nicholas

A High Threshold of Biotherapeutic Aggregate Numbers is Needed to Induce an Immunogenic Response In Vitro , In Vivo , and in the Clinic

• Joseph R. Cohen
• Stephen R. Brych
• Marisa K. Joubert

Evaluation of Pharmacokinetic and Pharmacodynamic (PK/PD) of Novel Fluorenylmethoxycarbonyl- Phenylalanine Antimicrobial Agent

• Avinash Y. Gahane
• Devesh Pratap Verma
• Ashwani K. Thakur

Journal updates

The aaps journals make use of portable peer review.

If your manuscript has been declined, and you are planning to submit your article to another of the four AAPS journals ( AAPS Open, The AAPS Journal, AAPSPharmSciTech , or Pharmaceutical Research ), we can help make the peer review process faster and smoother by extending the use of previous peer reviewer comments! Portable Peer Review, an opt-into service available for any author of these journals, allows us to share, between the portfolio, previous peer review comments and reviewer names, subject to approval of all parties. This can help speed up the assessment process, should the editor choose to make a decision on the basis of the comments and revision. Interested?   Email us with the name of the journal to which you are going to submit. Note: Portable peer review is opt-in only, available at the authors’ preference, and the reviewer identities and comments will only be shared between offices, not to the author.

AAPS Pharmaceutical Research Meritorious Manuscript Award

AAPS Pharmaceutical Research Meritorious Manuscript Award Recognizing outstanding achievement in the pharmaceutical sciences as demonstrated by the author(s) in the quality and originality of a manuscript published in Pharmaceutical Research.  Watch the video here .

Awardee/Corresponding Author: Dennis Douroumis, Ph.D., University of Greenwich Co-Authors: Nicolaos Scoutaris, Ph.D. and Steven A. Ross, Ph.D.

Featured article

Repurposing of kinase inhibitors for treatment of COVID-19 There are three major needs that have yet to be met for effective management of COVID19 disease: 1) anti-viral therapies that limit viral transmission, cell entry, and replication, 2) therapies that attenuate the non-productive immune response and thus decrease end-organ damage, and 3) therapies that have an anti-fibrotic effect in patients with ARDS and thus decrease long-term sequelae of disease. Read the article above for the full review and proposal.

Announcing new Editor-in-Chief of AAPS Open: Dr. Andrea Allmendinger

AAPS Open is proud to announce new Editor-in-Chief Dr. Andrea Allmendinger. Dr. Allmendinger obtained her PhD in Pharmaceutical Technology from the University of Basel and joined the Pharmaceutical Development department of Roche/Genentech in Basel in 2013, where she is responsible for formulation and process development for clinical Phase I-III projects and commercial transfer activities for both large molecules and for synthetic drugs.

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Title proper: Journal of chemical and pharmaceutical research.

Country: India

Medium: Online

Record information

Last modification date: 06/02/2021

Type of record: Confirmed

ISSN Center responsible of the record: ISSN National Centre for India

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Journal of Chemical and Pharmaceutical Sciences

Discontinued in Scopus as of 2016

Subject Area and Category

• Biochemistry, Genetics and Molecular Biology (miscellaneous)
• Pharmaceutical Science
• Pharmacology

SPB Pharma Society

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Information.

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The set of journals have been ranked according to their SJR and divided into four equal groups, four quartiles. Q1 (green) comprises the quarter of the journals with the highest values, Q2 (yellow) the second highest values, Q3 (orange) the third highest values and Q4 (red) the lowest values.

The SJR is a size-independent prestige indicator that ranks journals by their 'average prestige per article'. It is based on the idea that 'all citations are not created equal'. SJR is a measure of scientific influence of journals that accounts for both the number of citations received by a journal and the importance or prestige of the journals where such citations come from It measures the scientific influence of the average article in a journal, it expresses how central to the global scientific discussion an average article of the journal is.

Evolution of the number of published documents. All types of documents are considered, including citable and non citable documents.

This indicator counts the number of citations received by documents from a journal and divides them by the total number of documents published in that journal. The chart shows the evolution of the average number of times documents published in a journal in the past two, three and four years have been cited in the current year. The two years line is equivalent to journal impact factor ™ (Thomson Reuters) metric.

Evolution of the total number of citations and journal's self-citations received by a journal's published documents during the three previous years. Journal Self-citation is defined as the number of citation from a journal citing article to articles published by the same journal.

Evolution of the number of total citation per document and external citation per document (i.e. journal self-citations removed) received by a journal's published documents during the three previous years. External citations are calculated by subtracting the number of self-citations from the total number of citations received by the journal’s documents.

International Collaboration accounts for the articles that have been produced by researchers from several countries. The chart shows the ratio of a journal's documents signed by researchers from more than one country; that is including more than one country address.

Not every article in a journal is considered primary research and therefore "citable", this chart shows the ratio of a journal's articles including substantial research (research articles, conference papers and reviews) in three year windows vs. those documents other than research articles, reviews and conference papers.

Ratio of a journal's items, grouped in three years windows, that have been cited at least once vs. those not cited during the following year.

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Green Chemistry

Photochemical selective difluoroalkylation reactions of bicyclobutanes: direct sustainable pathways to functionalized bioisosteres for drug discovery.

In the realm of organic and green chemistry, the functionalization of cyclobutanes presents a significant challenge, given their unique structural properties and biological relevance. Particularly, the introduction of difluoromethyl groups into cyclobutane frameworks is a burgeoning area of interest due to its potential in drug design and synthesis. However, the construction of difluoromethyl cyclobutanes heavily relies on environmentally burdensome fluorination of cyclobutyl ketones. Methods to efficiently and directly introduce difluoromethyl groups to cyclobutanes remain underexplored. This study introduces a novel photochemical protocol for the selective difluoromethylation or bromo difluoromethylation of bicyclobutanes, leveraging green solvent-controlled reactions. Remarkably, this method takes the merits toward both green chemistry and organic chemistry such as renewable visible-light as reaction power, high atomic-economy and fully controlled chemo-selectivity. The work also unravels the mechanism behind the remarkable selectivity achieved. Emphasizing the importance of difluoromethyl cyclobutane scaffolds as bioisosteres, this research not only broadens the chemical space in organic synthesis but also offers new avenues for pharmaceutical discovery. The findings demonstrate the method's robustness and versatility, including its applicability to drug modifications, addressing a crucial gap in the green synthesis of complex medicinal molecule.

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Y. Duan, Y. Xu, Y. Li, L. Mao, J. Feng, R. Zhang, W. Tang, T. Lu, Y. Chen and J. Feng, Green Chem. , 2024, Accepted Manuscript , DOI: 10.1039/D4GC00703D

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Chemical & Pharmaceutical Research

Open access issn: 2689-1050.

Chemical & Pharmaceutical Research is an international journal dedicated to publishing various disciplines of articles in Chemistry, Pharmacy & Pharmaceutical Research. The journal has been designed to cover all the fields of Chemical Sciences like Organic Chemistry, Green Chemistry, Photochemistry, Inorganic Chemistry, Physical Chemistry, Industrial Chemistry, Biochemistry, Environmental Chemistry, Agricultural & Soil Chemistry, Analytical Chemistry, Polymer Chemistry, Macromolecular Chemistry, Petroleum Chemistry, Forensic Chemistry and Phytochemistry as well as all aspects of Pharmaceutical Technology, Pharmacognosy, Natural Product Research, Pharmaceutics, Novel Drug Delivery, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Modafinil Drug Design, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Bioinformatics, Pharmacoeconomics and Outcomes Research and Biotechnology of Pharmaceutical Interest.

Our journal publishes research papers, reviews, short communications and editorials dealing with entire aspects of chemistry and pharma research.

Chemical & Pharmaceutical Research strongly supports the Open Access initiative. All published articles will be assigned DOI provided by Cross Ref. Chemical & Pharmaceutical Research will keep up-to-date with the latest advancements in the feilds of chemistry and pharmaceutics. Abstracts and Pdfs of all articles published are freely available to everyone immediately after publication.

Authors are requested to submit manuscripts as an e-mail attachment to the Editorial Office at [email protected] .

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Elevated cardiopulmonary complications after revascularization in patients with severe mental health disorders.

Authors: Leah Gober, Adam Brown, Avianne P Bunnell, Brian E Bunnell, Jean Marie Ruddy DOI: 10.33425/2639-8486.1122

Maternal Hyperglycemia Induces Changes in Gene Expression and Morphology in Mouse Placentas

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