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• Control Groups and Treatment Groups | Uses & Examples

Control Groups and Treatment Groups | Uses & Examples

Published on July 3, 2020 by Lauren Thomas . Revised on June 22, 2023.

In a scientific study, a control group is used to establish causality by isolating the effect of an independent variable .

Here, researchers change the independent variable in the treatment group and keep it constant in the control group. Then they compare the results of these groups.

Using a control group means that any change in the dependent variable can be attributed to the independent variable. This helps avoid extraneous variables or confounding variables from impacting your work, as well as a few types of research bias , like omitted variable bias .

Table of contents

Control groups in experiments, control groups in non-experimental research, importance of control groups, other interesting articles, frequently asked questions about control groups.

Control groups are essential to experimental design . When researchers are interested in the impact of a new treatment, they randomly divide their study participants into at least two groups:

• The treatment group (also called the experimental group ) receives the treatment whose effect the researcher is interested in.
• The control group receives either no treatment, a standard treatment whose effect is already known, or a placebo (a fake treatment to control for placebo effect ).

The treatment is any independent variable manipulated by the experimenters, and its exact form depends on the type of research being performed. In a medical trial, it might be a new drug or therapy. In public policy studies, it could be a new social policy that some receive and not others.

In a well-designed experiment, all variables apart from the treatment should be kept constant between the two groups. This means researchers can correctly measure the entire effect of the treatment without interference from confounding variables .

• You pay the students in the treatment group for achieving high grades.
• Students in the control group do not receive any money.

Studies can also include more than one treatment or control group. Researchers might want to examine the impact of multiple treatments at once, or compare a new treatment to several alternatives currently available.

• The treatment group gets the new pill.
• Control group 1 gets an identical-looking sugar pill (a placebo)
• Control group 2 gets a pill already approved to treat high blood pressure

Since the only variable that differs between the three groups is the type of pill, any differences in average blood pressure between the three groups can be credited to the type of pill they received.

• The difference between the treatment group and control group 1 demonstrates the effectiveness of the pill as compared to no treatment.
• The difference between the treatment group and control group 2 shows whether the new pill improves on treatments already available on the market.

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Although control groups are more common in experimental research, they can be used in other types of research too. Researchers generally rely on non-experimental control groups in two cases: quasi-experimental or matching design.

Control groups in quasi-experimental design

While true experiments rely on random assignment to the treatment or control groups, quasi-experimental design uses some criterion other than randomization to assign people.

Often, these assignments are not controlled by researchers, but are pre-existing groups that have received different treatments. For example, researchers could study the effects of a new teaching method that was applied in some classes in a school but not others, or study the impact of a new policy that is implemented in one state but not in the neighboring state.

In these cases, the classes that did not use the new teaching method, or the state that did not implement the new policy, is the control group.

Control groups in matching design

In correlational research , matching represents a potential alternate option when you cannot use either true or quasi-experimental designs.

In matching designs, the researcher matches individuals who received the “treatment”, or independent variable under study, to others who did not–the control group.

Each member of the treatment group thus has a counterpart in the control group identical in every way possible outside of the treatment. This ensures that the treatment is the only source of potential differences in outcomes between the two groups.

Control groups help ensure the internal validity of your research. You might see a difference over time in your dependent variable in your treatment group. However, without a control group, it is difficult to know whether the change has arisen from the treatment. It is possible that the change is due to some other variables.

If you use a control group that is identical in every other way to the treatment group, you know that the treatment–the only difference between the two groups–must be what has caused the change.

For example, people often recover from illnesses or injuries over time regardless of whether they’ve received effective treatment or not. Thus, without a control group, it’s difficult to determine whether improvements in medical conditions come from a treatment or just the natural progression of time.

Risks from invalid control groups

If your control group differs from the treatment group in ways that you haven’t accounted for, your results may reflect the interference of confounding variables instead of your independent variable.

Minimizing this risk

A few methods can aid you in minimizing the risk from invalid control groups.

• Ensure that all potential confounding variables are accounted for , preferably through an experimental design if possible, since it is difficult to control for all the possible confounders outside of an experimental environment.
• Use double-blinding . This will prevent the members of each group from modifying their behavior based on whether they were placed in the treatment or control group, which could then lead to biased outcomes.
• Randomly assign your subjects into control and treatment groups. This method will allow you to not only minimize the differences between the two groups on confounding variables that you can directly observe, but also those you cannot.

If you want to know more about statistics , methodology , or research bias , make sure to check out some of our other articles with explanations and examples.

• Student’s  t -distribution
• Normal distribution
• Null and Alternative Hypotheses
• Chi square tests
• Confidence interval
• Quartiles & Quantiles
• Cluster sampling
• Stratified sampling
• Data cleansing
• Reproducibility vs Replicability
• Peer review
• Prospective cohort study

Research bias

• Implicit bias
• Cognitive bias
• Placebo effect
• Hawthorne effect
• Hindsight bias
• Affect heuristic
• Social desirability bias

An experimental group, also known as a treatment group, receives the treatment whose effect researchers wish to study, whereas a control group does not. They should be identical in all other ways.

A true experiment (a.k.a. a controlled experiment) always includes at least one control group that doesn’t receive the experimental treatment.

However, some experiments use a within-subjects design to test treatments without a control group. In these designs, you usually compare one group’s outcomes before and after a treatment (instead of comparing outcomes between different groups).

For strong internal validity , it’s usually best to include a control group if possible. Without a control group, it’s harder to be certain that the outcome was caused by the experimental treatment and not by other variables.

A confounding variable , also called a confounder or confounding factor, is a third variable in a study examining a potential cause-and-effect relationship.

A confounding variable is related to both the supposed cause and the supposed effect of the study. It can be difficult to separate the true effect of the independent variable from the effect of the confounding variable.

In your research design , it’s important to identify potential confounding variables and plan how you will reduce their impact.

There are several methods you can use to decrease the impact of confounding variables on your research: restriction, matching, statistical control and randomization.

In restriction , you restrict your sample by only including certain subjects that have the same values of potential confounding variables.

In matching , you match each of the subjects in your treatment group with a counterpart in the comparison group. The matched subjects have the same values on any potential confounding variables, and only differ in the independent variable .

In statistical control , you include potential confounders as variables in your regression .

In randomization , you randomly assign the treatment (or independent variable) in your study to a sufficiently large number of subjects, which allows you to control for all potential confounding variables.

Experimental design means planning a set of procedures to investigate a relationship between variables . To design a controlled experiment, you need:

• A testable hypothesis
• At least one independent variable that can be precisely manipulated
• At least one dependent variable that can be precisely measured

When designing the experiment, you decide:

• How you will manipulate the variable(s)
• How you will control for any potential confounding variables
• How many subjects or samples will be included in the study
• How subjects will be assigned to treatment levels

Experimental design is essential to the internal and external validity of your experiment.

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• Knowledge Base
• Methodology
• Control Groups and Treatment Groups | Uses & Examples

Control Groups & Treatment Groups | Uses & Examples

Published on 6 May 2022 by Lauren Thomas . Revised on 13 April 2023.

In a scientific study, a control group is used to establish a cause-and-effect relationship by isolating the effect of an independent variable .

Researchers change the independent variable in the treatment group and keep it constant in the control group. Then they compare the results of these groups.

Using a control group means that any change in the dependent variable can be attributed to the independent variable.

Table of contents

Control groups in experiments, control groups in non-experimental research, importance of control groups, frequently asked questions about control groups.

Control groups are essential to experimental design . When researchers are interested in the impact of a new treatment, they randomly divide their study participants into at least two groups:

• The treatment group (also called the experimental group ) receives the treatment whose effect the researcher is interested in.
• The control group receives either no treatment, a standard treatment whose effect is already known, or a placebo (a fake treatment).

The treatment is any independent variable manipulated by the experimenters, and its exact form depends on the type of research being performed. In a medical trial, it might be a new drug or therapy. In public policy studies, it could be a new social policy that some receive and not others.

In a well-designed experiment, all variables apart from the treatment should be kept constant between the two groups. This means researchers can correctly measure the entire effect of the treatment without interference from confounding variables .

• You pay the students in the treatment group for achieving high grades.
• Students in the control group do not receive any money.

Studies can also include more than one treatment or control group. Researchers might want to examine the impact of multiple treatments at once, or compare a new treatment to several alternatives currently available.

• The treatment group gets the new pill.
• Control group 1 gets an identical-looking sugar pill (a placebo).
• Control group 2 gets a pill already approved to treat high blood pressure.

Since the only variable that differs between the three groups is the type of pill, any differences in average blood pressure between the three groups can be credited to the type of pill they received.

• The difference between the treatment group and control group 1 demonstrates the effectiveness of the pill as compared to no treatment.
• The difference between the treatment group and control group 2 shows whether the new pill improves on treatments already available on the market.

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Although control groups are more common in experimental research, they can be used in other types of research too. Researchers generally rely on non-experimental control groups in two cases: quasi-experimental or matching design.

Control groups in quasi-experimental design

While true experiments rely on random assignment to the treatment or control groups, quasi-experimental design uses some criterion other than randomisation to assign people.

Often, these assignments are not controlled by researchers, but are pre-existing groups that have received different treatments. For example, researchers could study the effects of a new teaching method that was applied in some classes in a school but not others, or study the impact of a new policy that is implemented in one region but not in the neighbouring region.

In these cases, the classes that did not use the new teaching method, or the region that did not implement the new policy, is the control group.

Control groups in matching design

In correlational research , matching represents a potential alternate option when you cannot use either true or quasi-experimental designs.

In matching designs, the researcher matches individuals who received the ‘treatment’, or independent variable under study, to others who did not – the control group.

Each member of the treatment group thus has a counterpart in the control group identical in every way possible outside of the treatment. This ensures that the treatment is the only source of potential differences in outcomes between the two groups.

Control groups help ensure the internal validity of your research. You might see a difference over time in your dependent variable in your treatment group. However, without a control group, it is difficult to know whether the change has arisen from the treatment. It is possible that the change is due to some other variables.

If you use a control group that is identical in every other way to the treatment group, you know that the treatment – the only difference between the two groups – must be what has caused the change.

For example, people often recover from illnesses or injuries over time regardless of whether they’ve received effective treatment or not. Thus, without a control group, it’s difficult to determine whether improvements in medical conditions come from a treatment or just the natural progression of time.

Risks from invalid control groups

If your control group differs from the treatment group in ways that you haven’t accounted for, your results may reflect the interference of confounding variables instead of your independent variable.

Minimising this risk

A few methods can aid you in minimising the risk from invalid control groups.

• Ensure that all potential confounding variables are accounted for , preferably through an experimental design if possible, since it is difficult to control for all the possible confounders outside of an experimental environment.
• Use double-blinding . This will prevent the members of each group from modifying their behavior based on whether they were placed in the treatment or control group, which could then lead to biased outcomes.
• Randomly assign your subjects into control and treatment groups. This method will allow you to not only minimise the differences between the two groups on confounding variables that you can directly observe, but also those you cannot.

An experimental group, also known as a treatment group, receives the treatment whose effect researchers wish to study, whereas a control group does not. They should be identical in all other ways.

A true experiment (aka a controlled experiment) always includes at least one control group that doesn’t receive the experimental treatment.

However, some experiments use a within-subjects design to test treatments without a control group. In these designs, you usually compare one group’s outcomes before and after a treatment (instead of comparing outcomes between different groups).

For strong internal validity , it’s usually best to include a control group if possible. Without a control group, it’s harder to be certain that the outcome was caused by the experimental treatment and not by other variables.

In a controlled experiment , all extraneous variables are held constant so that they can’t influence the results. Controlled experiments require:

• A control group that receives a standard treatment, a fake treatment, or no treatment
• Random assignment of participants to ensure the groups are equivalent

Depending on your study topic, there are various other methods of controlling variables .

A confounding variable , also called a confounder or confounding factor, is a third variable in a study examining a potential cause-and-effect relationship.

A confounding variable is related to both the supposed cause and the supposed effect of the study. It can be difficult to separate the true effect of the independent variable from the effect of the confounding variable.

In your research design , it’s important to identify potential confounding variables and plan how you will reduce their impact.

Cite this Scribbr article

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Thomas, L. (2023, April 13). Control Groups & Treatment Groups | Uses & Examples. Scribbr. Retrieved 25 March 2024, from https://www.scribbr.co.uk/research-methods/control-groups/

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Lauren Thomas

Other students also liked, controlled experiments | methods & examples of control, a quick guide to experimental design | 5 steps & examples, correlation vs causation | differences, designs & examples.

Random Assignment in Psychology: Definition & Examples

Julia Simkus

Editor at Simply Psychology

BA (Hons) Psychology, Princeton University

Julia Simkus is a graduate of Princeton University with a Bachelor of Arts in Psychology. She is currently studying for a Master's Degree in Counseling for Mental Health and Wellness in September 2023. Julia's research has been published in peer reviewed journals.

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Saul Mcleod, PhD

Editor-in-Chief for Simply Psychology

BSc (Hons) Psychology, MRes, PhD, University of Manchester

Saul Mcleod, PhD., is a qualified psychology teacher with over 18 years of experience in further and higher education. He has been published in peer-reviewed journals, including the Journal of Clinical Psychology.

Olivia Guy-Evans, MSc

Associate Editor for Simply Psychology

BSc (Hons) Psychology, MSc Psychology of Education

Olivia Guy-Evans is a writer and associate editor for Simply Psychology. She has previously worked in healthcare and educational sectors.

In psychology, random assignment refers to the practice of allocating participants to different experimental groups in a study in a completely unbiased way, ensuring each participant has an equal chance of being assigned to any group.

In experimental research, random assignment, or random placement, organizes participants from your sample into different groups using randomization. 

Random assignment uses chance procedures to ensure that each participant has an equal opportunity of being assigned to either a control or experimental group.

The control group does not receive the treatment in question, whereas the experimental group does receive the treatment.

When using random assignment, neither the researcher nor the participant can choose the group to which the participant is assigned. This ensures that any differences between and within the groups are not systematic at the onset of the study. 

In a study to test the success of a weight-loss program, investigators randomly assigned a pool of participants to one of two groups.

Group A participants participated in the weight-loss program for 10 weeks and took a class where they learned about the benefits of healthy eating and exercise.

Group B participants read a 200-page book that explains the benefits of weight loss. The investigator randomly assigned participants to one of the two groups.

The researchers found that those who participated in the program and took the class were more likely to lose weight than those in the other group that received only the book.

Importance 

Random assignment ensures that each group in the experiment is identical before applying the independent variable.

In experiments , researchers will manipulate an independent variable to assess its effect on a dependent variable, while controlling for other variables. Random assignment increases the likelihood that the treatment groups are the same at the onset of a study.

Thus, any changes that result from the independent variable can be assumed to be a result of the treatment of interest. This is particularly important for eliminating sources of bias and strengthening the internal validity of an experiment.

Random assignment is the best method for inferring a causal relationship between a treatment and an outcome.

Random Selection vs. Random Assignment 

Random selection (also called probability sampling or random sampling) is a way of randomly selecting members of a population to be included in your study.

On the other hand, random assignment is a way of sorting the sample participants into control and treatment groups. 

Random selection ensures that everyone in the population has an equal chance of being selected for the study. Once the pool of participants has been chosen, experimenters use random assignment to assign participants into groups. 

Random assignment is only used in between-subjects experimental designs, while random selection can be used in a variety of study designs.

Random Assignment vs Random Sampling

Random sampling refers to selecting participants from a population so that each individual has an equal chance of being chosen. This method enhances the representativeness of the sample.

Random assignment, on the other hand, is used in experimental designs once participants are selected. It involves allocating these participants to different experimental groups or conditions randomly.

This helps ensure that any differences in results across groups are due to manipulating the independent variable, not preexisting differences among participants.

When to Use Random Assignment

Random assignment is used in experiments with a between-groups or independent measures design.

In these research designs, researchers will manipulate an independent variable to assess its effect on a dependent variable, while controlling for other variables.

There is usually a control group and one or more experimental groups. Random assignment helps ensure that the groups are comparable at the onset of the study.

How to Use Random Assignment

There are a variety of ways to assign participants into study groups randomly. Here are a handful of popular methods: 

• Random Number Generator : Give each member of the sample a unique number; use a computer program to randomly generate a number from the list for each group.
• Lottery : Give each member of the sample a unique number. Place all numbers in a hat or bucket and draw numbers at random for each group.
• Flipping a Coin : Flip a coin for each participant to decide if they will be in the control group or experimental group (this method can only be used when you have just two groups) 
• Roll a Die : For each number on the list, roll a dice to decide which of the groups they will be in. For example, assume that rolling 1, 2, or 3 places them in a control group and rolling 3, 4, 5 lands them in an experimental group.

When is Random Assignment not used?

• When it is not ethically permissible: Randomization is only ethical if the researcher has no evidence that one treatment is superior to the other or that one treatment might have harmful side effects. 
• When answering non-causal questions : If the researcher is just interested in predicting the probability of an event, the causal relationship between the variables is not important and observational designs would be more suitable than random assignment. 
• When studying the effect of variables that cannot be manipulated: Some risk factors cannot be manipulated and so it would not make any sense to study them in a randomized trial. For example, we cannot randomly assign participants into categories based on age, gender, or genetic factors.

Drawbacks of Random Assignment

While randomization assures an unbiased assignment of participants to groups, it does not guarantee the equality of these groups. There could still be extraneous variables that differ between groups or group differences that arise from chance. Additionally, there is still an element of luck with random assignments.

Thus, researchers can not produce perfectly equal groups for each specific study. Differences between the treatment group and control group might still exist, and the results of a randomized trial may sometimes be wrong, but this is absolutely okay.

Scientific evidence is a long and continuous process, and the groups will tend to be equal in the long run when data is aggregated in a meta-analysis.

Additionally, external validity (i.e., the extent to which the researcher can use the results of the study to generalize to the larger population) is compromised with random assignment.

Random assignment is challenging to implement outside of controlled laboratory conditions and might not represent what would happen in the real world at the population level. 

Random assignment can also be more costly than simple observational studies, where an investigator is just observing events without intervening with the population.

Randomization also can be time-consuming and challenging, especially when participants refuse to receive the assigned treatment or do not adhere to recommendations. 

What is the difference between random sampling and random assignment?

Random sampling refers to randomly selecting a sample of participants from a population. Random assignment refers to randomly assigning participants to treatment groups from the selected sample.

Does random assignment increase internal validity?

Yes, random assignment ensures that there are no systematic differences between the participants in each group, enhancing the study’s internal validity .

Does random assignment reduce sampling error?

Yes, with random assignment, participants have an equal chance of being assigned to either a control group or an experimental group, resulting in a sample that is, in theory, representative of the population.

Random assignment does not completely eliminate sampling error because a sample only approximates the population from which it is drawn. However, random sampling is a way to minimize sampling errors. 

When is random assignment not possible?

Random assignment is not possible when the experimenters cannot control the treatment or independent variable.

For example, if you want to compare how men and women perform on a test, you cannot randomly assign subjects to these groups.

Participants are not randomly assigned to different groups in this study, but instead assigned based on their characteristics.

Does random assignment eliminate confounding variables?

Yes, random assignment eliminates the influence of any confounding variables on the treatment because it distributes them at random among the study groups. Randomization invalidates any relationship between a confounding variable and the treatment.

Why is random assignment of participants to treatment conditions in an experiment used?

Random assignment is used to ensure that all groups are comparable at the start of a study. This allows researchers to conclude that the outcomes of the study can be attributed to the intervention at hand and to rule out alternative explanations for study results.

Further Reading

• Bogomolnaia, A., & Moulin, H. (2001). A new solution to the random assignment problem .  Journal of Economic theory ,  100 (2), 295-328.
• Krause, M. S., & Howard, K. I. (2003). What random assignment does and does not do .  Journal of Clinical Psychology ,  59 (7), 751-766.

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What Is a Control Group?

Control Groups vs. Experimental Groups in Psychology Research

Kendra Cherry, MS, is a psychosocial rehabilitation specialist, psychology educator, and author of the "Everything Psychology Book."

Emily is a board-certified science editor who has worked with top digital publishing brands like Voices for Biodiversity, Study.com, GoodTherapy, Vox, and Verywell.

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Control Group vs. Experimental Group

Types of control groups.

In simple terms, the control group comprises participants who do not receive the experimental treatment. When conducting an experiment, these people are randomly assigned to this group. They also closely resemble the participants who are in the experimental group or the individuals who receive the treatment.

Experimenters utilize variables to make comparisons between an experimental group and a control group. A variable is something that researchers can manipulate, measure, and control in an experiment. The independent variable is the aspect of the experiment that the researchers manipulate (or the treatment). The dependent variable is what the researchers measure to see if the independent variable had an effect.

While they do not receive the treatment, the control group does play a vital role in the research process. Experimenters compare the experimental group to the control group to determine if the treatment had an effect.

By serving as a comparison group, researchers can isolate the independent variable and look at the impact it had.

The simplest way to determine the difference between a control group and an experimental group is to determine which group receives the treatment and which does not. To ensure that the results can then be compared accurately, the two groups should be otherwise identical.

Not exposed to the treatment (the independent variable)

Used to provide a baseline to compare results against

May receive a placebo treatment

Exposed to the treatment

Used to measure the effects of the independent variable

Identical to the control group aside from their exposure to the treatment

Why a Control Group Is Important

While the control group does not receive treatment, it does play a critical role in the experimental process. This group serves as a benchmark, allowing researchers to compare the experimental group to the control group to see what sort of impact changes to the independent variable produced.  

Because participants have been randomly assigned to either the control group or the experimental group, it can be assumed that the groups are comparable.

Any differences between the two groups are, therefore, the result of the manipulations of the independent variable. The experimenters carry out the exact same procedures with both groups with the exception of the manipulation of the independent variable in the experimental group.

There are a number of different types of control groups that might be utilized in psychology research. Some of these include:

• Positive control groups : In this case, researchers already know that a treatment is effective but want to learn more about the impact of variations of the treatment. In this case, the control group receives the treatment that is known to work, while the experimental group receives the variation so that researchers can learn more about how it performs and compares to the control.
• Negative control group : In this type of control group, the participants are not given a treatment. The experimental group can then be compared to the group that did not experience any change or results.
• Placebo control group : This type of control group receives a placebo treatment that they believe will have an effect. This control group allows researchers to examine the impact of the placebo effect and how the experimental treatment compared to the placebo treatment.
• Randomized control group : This type of control group involves using random selection to help ensure that the participants in the control group accurately reflect the demographics of the larger population.
• Natural control group : This type of control group is naturally selected, often by situational factors. For example, researchers might compare people who have experienced trauma due to war to people who have not experienced war. The people who have not experienced war-related trauma would be the control group.

Examples of Control Groups

Control groups can be used in a variety of situations. For example, imagine a study in which researchers example how distractions during an exam influence test results. The control group would take an exam in a setting with no distractions, while the experimental groups would be exposed to different distractions. The results of the exam would then be compared to see the effects that distractions had on test scores.

Experiments that look at the effects of medications on certain conditions are also examples of how a control group can be used in research. For example, researchers looking at the effectiveness of a new antidepressant might use a control group that receives a placebo and an experimental group that receives the new medication. At the end of the study, researchers would compare measures of depression for both groups to determine what impact the new medication had.

After the experiment is complete, researchers can then look at the test results and start making comparisons between the control group and the experimental group.

Uses for Control Groups

Researchers utilize control groups to conduct research in a range of different fields. Some common uses include:

• Psychology : Researchers utilize control groups to learn more about mental health, behaviors, and treatments.
• Medicine : Control groups can be used to learn more about certain health conditions, assess how well medications work to treat these conditions, and assess potential side effects that may result.
• Education : Educational researchers utilize control groups to learn more about how different curriculums, programs, or instructional methods impact student outcomes.
• Marketing : Researchers utilize control groups to learn more about how consumers respond to advertising and marketing efforts.

Malay S, Chung KC. The choice of controls for providing validity and evidence in clinical research . Plast Reconstr Surg. 2012 Oct;130(4):959-965. doi:10.1097/PRS.0b013e318262f4c8

National Cancer Institute. Control group.

Pithon MM. Importance of the control group in scientific research . Dental Press J Orthod. 2013;18(6):13-14. doi:10.1590/s2176-94512013000600003

Karlsson P, Bergmark A. Compared with what? An analysis of control-group types in Cochrane and Campbell reviews of psychosocial treatment efficacy with substance use disorders . Addiction . 2015;110(3):420-8. doi:10.1111/add.12799

Myers A, Hansen C. Experimental Psychology . Belmont, CA: Cengage Learning; 2012.

By Kendra Cherry, MSEd Kendra Cherry, MS, is a psychosocial rehabilitation specialist, psychology educator, and author of the "Everything Psychology Book."