depression personal essay

I Have Depression, and I'm Proof That You Never Know the Battle Someone Is Waging Inside

Updated on 2/27/2020 at 7:50 AM

I never thought I'd live to be 26 years old. You may be wondering why someone who seems perfectly healthy would have such a dark thought , and you would not be alone. But I'm proud to say that turning 26 has been one of the greatest accomplishments of my life.

If you checked my Instagram over the last few years, you would have seen me as the happiest girl in the world , traveling the globe teaching yoga and weightlifting. But keeping up that image grew exhausting, so I decided to be brave and tell my story. My story is not unique, but it's one that is rarely spoken about due to fear. Fear can be a crippling emotion, but it can also be a powerful tool.

Depression and anxiety are just like any other illness. They're nothing to hide away.

So I'm going to ask something scary: do the words "mental health" make you uncomfortable? They used to make me feel that way, too. But depression and anxiety are just like any other illness. They're nothing to hide away. In fact, these journeys should be shared and celebrated.

I have had anxiety for as long as I can remember. Growing up, it impacted every part of life. I would have panic attacks before going to school, sleepless nights before games or tests, endless thoughts of everyone being against me, and days where I felt completely alone in the world. In college, things got worse. I became extremely depressed. I partied every chance I got. I hung out with people who fed the worst parts of me. I protected myself by flashing a big smile and playing the part of the bubbly sorority girl. I told myself that depression is scary and no one wants to hear about that .

Keep it hidden and keep smiling.

A few years later, at the age of 20, my smile had fallen and I had given up. The thought of waking up the next morning was too much for me to handle. I was no longer anxious or sad; instead I felt numb, and that's when things took a turn for the worse. I called my dad, who lived across the country, and for the first time in my life, I told him everything. It was too late, though. I was not calling for help. I was calling to say goodbye.

Miraculously, he convinced me to hang on for a few more hours. Had he not boarded the very next flight to me, I would not be here right now.

That is when I started my long and continuous journey to get healthy. I worked with doctors and therapists , but I still struggled. Until one day my dad took me to a CrossFit gym by my school and for the first time I picked up a barbell. It instantly became my place to escape, my outlet, my medicine . I did not go more than a day without having a bar in my hand, but weightlifting and fitness were not enough alone.

After a year or so, the depression crept back in. I channeled the inner strength I had built in the gym and asked for help. This is when I began working with a new therapist, one who believed that depression decreased by age 26. I have no idea if this is true, but in yoga, you're taught not to ask if the thought is true, but rather if the thought serves you. So I hung onto this. When I fell into a really bad spell, I reminded myself, "Just a few more years. Hang on until you are 26. It will get better."

I kept lifting. I kept working. I kept growing.

As an Olympic weightlifting coach and yoga teacher, people tell me all the time how strong I am, which used to make me feel like a total fraud. But today, I am 26 years old. Today, I'm proudly sharing something I felt so ashamed of for so many years , and that's because I'm strong. I have a strength that this illness will never be able to match, not at 26 or any age after that.

The charity Project Semicolon is close to my heart. The idea behind it : "a semicolon represents a sentence an author could have ended, but chose not to." My story isn't over, and each chapter is a lot brighter, a lot bolder, and filled with a lot of fun new characters. There's always more to come. We just need to continue writing.

If you or a loved one are in need of any help, the National Suicide Prevention organization has several resources and a 24/7 lifeline at 1-800-273-8255.

• Healthy Living
• Personal Essay

• Depression: Major Depression & Unipolar Varieties

A Personal Story of Living through Depression

John Folk-Williams has lived with major depressive disorder since boyhood and finally achieved full recovery just a few years ago. As a survivor of ...Read More

A recovery story is a messy thing. It has dozens of beginnings and no final ending. Most of the conflict and drama is internal, and there’s a lot more inaction than action. The lead character hides in the shadows much of the time, so you can’t even see what’s going on.

I joined up with depression around the age of 8. There are snapshots of me in the shabby brown jacket I liked to wear. My mom took beautiful photographs, and there are lots of me in moody shadows, looking as down as could be.

She had her own depression to worry about. My typical memory of her from that time brings back a couch-bound, often napping, mother. She explained her sleep problem as a condition she called knockophasia – a term I’ve never been able to find in any dictionary. A few minutes after lying down, snap! Sound asleep. No one mentioned strange emotional problems or mental illness in those days. My parents occasionally talked about someone having a nervous breakdown as if they had died. There was no hint of a need to get help for my mother, much less for me. No one worried about me since I was a star in school, self-contained and impressive to teachers for being so mature, so adult.

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Migraine headaches started then, and increasingly intense anxiety about school. I missed many days, felt shame as if I were faking, and obsessed over every one of my failings. I spent long hours alone in my room.

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Through my teenage years, depression went underground. Feelings were dangerous. There were too many angry and violent ones shaking the house for me to add to them. So I kept emotion under wraps, even more so than in childhood. Nothing phased me outside the house and even at home I showed almost no sign of reaction to anything, even while churning with fear and anguish.

It was in my 20s that I broke open, and streams of depression, fear, panic, obsessive love and anger flowed out. In response to a panic attack that lasted for a week, I saw a psychiatrist. In one marathon session of 3 hours he helped me put the panic together with frightening episodes from my family life. I was cured on the spot but never went back to him. It was too soon to do any more.

It took another crisis a few years later to get me back to a psychiatrist and my first experience with medication – Elavil. But I had no idea what it was. I took something in the morning to get me going and something at night to help me sleep. I took it short term, got through the crisis but continued in therapy. From there I was steadily seeing psychiatrists in various cities for the next 8 years. But no one mentioned depression.

I first saw the word applied to my condition in a letter one psychiatrist wrote to the draft board during the Vietnam era. But I wasn’t treated for that problem. Therapy in those days was still in the Freudian tradition, and it was all about family life and conflict. Depression was a springboard for going deeper. Digging up the past to understand present problems was a tremendous help, and it changed me in many ways. But depression was still there in various forms, reappearing regularly for the next couple of decades. There were wonderfully happy and successful times as well, but I had these ups and downs through marriage, children and a couple of careers.

Gradually, depression became so disruptive that my wife couldn’t take it anymore and demanded I get help. So I finally did. This was the 1990s. Prozac had arrived, and I started a tour of medication over the next dozen years that didn’t do much at all. Nor did therapy, though two psychiatrists helped me to understand the more destructive patterns in my way of living.

Depression pushed into every corner of my existence, and both work and family life became more and more difficult. The medications only seemed to deaden my feelings and make me feel detached from everyone and immune to every pressure. It was like having pain signals turned off. There was no longer any sign coming from my body or brain that something might be wrong. I felt “fine” but relationships and work still went to hell.

The strange thing was that after all these years of living with it, I didn’t know very much about depression. I thought it was entirely a problem of depressed mood and loss of the energy and motivation. As things got worse, I finally started to read about it in great depth.

I was amazed to learn the full scope of depression and how pervasive it could be throughout the mind and body. I finally had a coherent, comprehensive picture of what depression was.

That was a big step because I could at last imagine the possibility of getting better. I could see that I wasn’t worthless by nature, that there were reasons my mind had trouble focusing and that the frequent slowdown in my speech and thinking was also rooted in this illness. Perhaps the right treatment could bring about fundamental changes after all.

There were still traps ahead, though. I became obsessed with the idea of depression as a brain disease. I studied all the forms of depression, the neurobiology and endless research studies. That was a good thing to do, but after awhile I was looking more at “Depression” than the details of my own version of the illness.

I wondered how many diagnostic categories I fitted into. For sure I had one or more of the anxiety disorders. Perhaps I fit into bipolar II instead of major depressive disorder. What about dissociation? I read the research study findings as if they were announcing my fate.

It was comforting to know I had a “real” disease. Not only could I answer any naysayers about the reality of depression. I also had a weapon to fight my internalized stigma, the lingering doubt that anything was wrong with me. I used to think that maybe I really was using the illness as a way to avoid life and cover up my own weakness. Here was proof that depression wasn’t all in my imagination but in my brain chemistry.

Neurobiology was far beyond my control. I couldn’t recover by myself. Doctors had to cure me through medication or other treatments, like ECT. However, that meant my hopes were pinned on them, not on my own role in getting better.

When the treatments failed to work, I got desperate that there would never be an end to depression. Hope in the future fell apart. My life would continue to run down. Could it even lead to suicide, as it had for friends of mine?

Fortunately, as I learned more, I listened to the experts who had a much broader view of the causes of the illness. Peter Kramer’s overview of research in Against Depression made it clear to me that contributors to the illness could include genetic inheritance, family history, traumatic events and stress as well as the misfiring of multiple body systems. No one could point to a single cause or boil it down to a few neurotransmitters.

So I went back to basics and looked much more closely at the particular symptoms I faced. I tracked the details in everyday living and saw that I needed to take the lead in recovery. Medication – when it had any effect at all – played a modest role in taking the edge off the worst symptoms. That bit of relief gave me the energy and presence of mind to work on the emotional and relationship impacts, to try to straighten out the parts of my life I had some control over.

I was determined to stop the waste of life in depression. I got back into psychotherapy and tried many types of self-help as well. Many didn’t work at all, but something inside pushed me to keep trying, despite setbacks.

One of the most important efforts was writing about my experience with depression. Writing is one way I discover things, but a deep fear had blocked me from doing it for years. I can see now that the real reason I got stuck was that I had been trying to write about everything but depression. When I could finally take that on directly, writing came naturally.

Blogging turned out to be the right medium. It was manageable even when I was down. The online community of people who lived with depression gave me a form of support that I had never had before. Another decisive step was getting out of high-stress work that I had been less and less able to do effectively. Taking that constant burden away restored a deep sense of vitality.

After all this, recovery finally started to happen. It took me by surprise, and for a long time I didn’t trust that it would last. But something had changed deep down. I believed in myself again, and the inner conviction of worthlessness disappeared.

I had found a deeply satisfying purpose in writing, as well as the energy and humor to do what I wanted to do. I regained the awareness and emotional presence to be a part of my family again, instead of the hidden husband and dad.

As anyone dealing with life-long depression will tell you, setbacks happen. There’s no simple happy ending. But if you’re lucky, an inner shift occurs, and the new normal is a decent life rather than depression. Self-awareness is key to good mental health. Take our online depression quiz today.

• Major And Unipolar Depression
• Related Conditions Part I
• Historical Understanding Part I
• Neurotransmitters
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• Classic Symptoms
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• Setting Limits
• Dysthymic Disorder
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• Tom Cruise Vs Brook Shields On Depression
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• Does Male Post-Partum Depression Exist?
• National Depression Screening Day
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Essays About Depression: Top 8 Examples Plus Prompts

Many people deal with mental health issues throughout their lives; if you are writing essays about depression, you can read essay examples to get started.

An occasional feeling of sadness is something that everyone experiences from time to time. Still, a persistent loss of interest, depressed mood, changes in energy levels, and sleeping problems can indicate mental illness. Thankfully, antidepressant medications, therapy, and other types of treatment can be largely helpful for people living with depression.

People suffering from depression or other mood disorders must work closely with a mental health professional to get the support they need to recover. While family members and other loved ones can help move forward after a depressive episode, it’s also important that people who have suffered from major depressive disorder work with a medical professional to get treatment for both the mental and physical problems that can accompany depression.

If you are writing an essay about depression, here are 8 essay examples to help you write an insightful essay. For help with your essays, check out our round-up of the best essay checkers .

• 1. My Best Friend Saved Me When I Attempted Suicide, But I Didn’t Save Her by Drusilla Moorhouse
• 2. How can I complain? by James Blake
• 3. What it’s like living with depression: A personal essay by Nadine Dirks
• 4. I Have Depression, and I’m Proof that You Never Know the Battle Someone is Waging Inside by Jac Gochoco
• 5. Essay: How I Survived Depression by Cameron Stout
• 6. I Can’t Get Out of My Sweat Pants: An Essay on Depression by Marisa McPeck-Stringham
• 7. This is what depression feels like by Courtenay Harris Bond

8. Opening Up About My Struggle with Recurring Depression by Nora Super

1. what is depression, 2. how is depression diagnosed, 3. causes of depression, 4. different types of depression, 5. who is at risk of depression, 6. can social media cause depression, 7. can anyone experience depression, the final word on essays about depression, is depression common, what are the most effective treatments for depression, top 8 examples, 1.  my best friend saved me when i attempted suicide, but i didn’t save her  by drusilla moorhouse.

“Just three months earlier, I had been a patient in another medical facility: a mental hospital. My best friend, Denise, had killed herself on Christmas, and days after the funeral, I told my mom that I wanted to die. I couldn’t forgive myself for the role I’d played in Denise’s death: Not only did I fail to save her, but I’m fairly certain I gave her the idea.”

Moorhouse makes painstaking personal confessions throughout this essay on depression, taking the reader along on the roller coaster of ups and downs that come with suicide attempts, dealing with the death of a loved one, and the difficulty of making it through major depressive disorder.

2.  How can I complain?  by James Blake

“I wanted people to know how I felt, but I didn’t have the vocabulary to tell them. I have gone into a bit of detail here not to make anyone feel sorry for me but to show how a privileged, relatively rich-and-famous-enough-for-zero-pity white man could become depressed against all societal expectations and allowances. If I can be writing this, clearly it isn’t only oppression that causes depression; for me it was largely repression.”

Musician James Blake shares his experience with depression and talks about his struggles with trying to grow up while dealing with existential crises just as he began to hit the peak of his fame. Blake talks about how he experienced guilt and shame around the idea that he had it all on the outside—and so many people deal with issues that he felt were larger than his.

3.  What it’s like living with depression: A personal essay   by Nadine Dirks

“In my early adulthood, I started to feel withdrawn, down, unmotivated, and constantly sad. What initially seemed like an off-day turned into weeks of painful feelings that seemed they would never let up. It was difficult to enjoy life with other people my age. Depression made typical, everyday tasks—like brushing my teeth—seem monumental. It felt like an invisible chain, keeping me in bed.”

Dirks shares her experience with depression and the struggle she faced to find treatment for mental health issues as a Black woman. Dirks discusses how even though she knew something about her mental health wasn’t quite right, she still struggled to get the diagnosis she needed to move forward and receive proper medical and psychological care.

4.  I Have Depression, and I’m Proof that You Never Know the Battle Someone is Waging Inside  by Jac Gochoco

“A few years later, at the age of 20, my smile had fallen, and I had given up. The thought of waking up the next morning was too much for me to handle. I was no longer anxious or sad; instead, I felt numb, and that’s when things took a turn for the worse. I called my dad, who lived across the country, and for the first time in my life, I told him everything. It was too late, though. I was not calling for help. I was calling to say goodbye.”

Gochoco describes the war that so many people with depression go through—trying to put on a brave face and a positive public persona while battling demons on the inside. The Olympic weightlifting coach and yoga instructor now work to share the importance of mental health with others.

5.  Essay: How I Survived Depression   by Cameron Stout

“In 1993, I saw a psychiatrist who prescribed an antidepressant. Within two months, the medication slowly gained traction. As the gray sludge of sadness and apathy washed away, I emerged from a spiral of impending tragedy. I helped raise two wonderful children, built a successful securities-litigation practice, and became an accomplished cyclist. I began to take my mental wellness for granted. “

Princeton alum Cameron Stout shared his experience with depression with his fellow Tigers in Princeton’s alumni magazine, proving that even the most brilliant and successful among us can be rendered powerless by a chemical imbalance. Stout shares his experience with treatment and how working with mental health professionals helped him to come out on the other side of depression.

6.  I Can’t Get Out of My Sweat Pants: An Essay on Depression  by Marisa McPeck-Stringham

“Sometimes, when the depression got really bad in junior high, I would come straight home from school and change into my pajamas. My dad caught on, and he said something to me at dinner time about being in my pajamas several days in a row way before bedtime. I learned it was better not to change into my pajamas until bedtime. People who are depressed like to hide their problematic behaviors because they are so ashamed of the way they feel. I was very ashamed and yet I didn’t have the words or life experience to voice what I was going through.”

McPeck-Stringham discusses her experience with depression and an eating disorder at a young age; both brought on by struggles to adjust to major life changes. The author experienced depression again in her adult life, and thankfully, she was able to fight through the illness using tried-and-true methods until she regained her mental health.

7.  This is what depression feels like  by Courtenay Harris Bond

“The smallest tasks seem insurmountable: paying a cell phone bill, lining up a household repair. Sometimes just taking a shower or arranging a play date feels like more than I can manage. My children’s squabbles make me want to scratch the walls. I want to claw out of my own skin. I feel like the light at the end of the tunnel is a solitary candle about to blow out at any moment. At the same time, I feel like the pain will never end.”

Bond does an excellent job of helping readers understand just how difficult depression can be, even for people who have never been through the difficulty of mental illness. Bond states that no matter what people believe the cause to be—chemical imbalance, childhood issues, a combination of the two—depression can make it nearly impossible to function.

“Once again, I spiraled downward. I couldn’t get out of bed. I couldn’t work. I had thoughts of harming myself. This time, my husband urged me to start ECT much sooner in the cycle, and once again, it worked. Within a matter of weeks I was back at work, pretending nothing had happened. I kept pushing myself harder to show everyone that I was “normal.” I thought I had a pattern: I would function at a high level for many years, and then my depression would be triggered by a significant event. I thought I’d be healthy for another ten years.”

Super shares her experience with electroconvulsive therapy and how her depression recurred with a major life event despite several years of solid mental health. Thankfully, Super was able to recognize her symptoms and get help sooner rather than later.

7 Writing Prompts on Essays About Depression

When writing essays on depression, it can be challenging to think of essay ideas and questions. Here are six essay topics about depression that you can use in your essay.

Depression can be difficult to define and understand. Discuss the definition of depression, and delve into the signs, symptoms, and possible causes of this mental illness. Depression can result from trauma or personal circumstances, but it can also be a health condition due to genetics. In your essay, look at how depression can be spotted and how it can affect your day-to-day life. 

Depression diagnosis can be complicated; this essay topic will be interesting as you can look at the different aspects considered in a diagnosis. While a certain lab test can be conducted, depression can also be diagnosed by a psychiatrist. Research the different ways depression can be diagnosed and discuss the benefits of receiving a diagnosis in this essay.

There are many possible causes of depression; this essay discusses how depression can occur. Possible causes of depression can include trauma, grief, anxiety disorders, and some physical health conditions. Look at each cause and discuss how they can manifest as depression.

There are many different types of depression. This essay topic will investigate each type of depression and its symptoms and causes. Depression symptoms can vary in severity, depending on what is causing it. For example, depression can be linked to medical conditions such as bipolar disorder. This is a different type of depression than depression caused by grief. Discuss the details of the different types of depression and draw comparisons and similarities between them.

Certain genetic traits, socio-economic circumstances, or age can make people more prone to experiencing symptoms of depression. Depression is becoming more and more common amongst young adults and teenagers. Discuss the different groups at risk of experiencing depression and how their circumstances contribute to this risk.

Social media poses many challenges to today’s youth, such as unrealistic beauty standards, cyber-bullying, and only seeing the “highlights” of someone’s life. Can social media cause depression in teens? Delve into the negative impacts of social media when writing this essay. You could compare the positive and negative sides of social media and discuss whether social media causes mental health issues amongst young adults and teenagers.

This essay question poses the question, “can anyone experience depression?” Although those in lower-income households may be prone to experiencing depression, can the rich and famous also experience depression? This essay discusses whether the privileged and wealthy can experience their possible causes. This is a great argumentative essay topic, discuss both sides of this question and draw a conclusion with your final thoughts.

When writing about depression, it is important to study examples of essays to make a compelling essay. You can also use your own research by conducting interviews or pulling information from other sources. As this is a sensitive topic, it is important to approach it with care; you can also write about your own experiences with mental health issues.

Tip: If writing an essay sounds like a lot of work, simplify it. Write a simple 5 paragraph essay instead.

FAQs On Essays About Depression

According to the World Health Organization, about 5% of people under 60 live with depression. The rate is slightly higher—around 6%—for people over 60. Depression can strike at any age, and it’s important that people who are experiencing symptoms of depression receive treatment, no matter their age. 

Suppose you’re living with depression or are experiencing some of the symptoms of depression. In that case, it’s important to work closely with your doctor or another healthcare professional to develop a treatment plan that works for you. A combination of antidepressant medication and cognitive behavioral therapy is a good fit for many people, but this isn’t necessarily the case for everyone who suffers from depression. Be sure to check in with your doctor regularly to ensure that you’re making progress toward improving your mental health.

If you’re still stuck, check out our general resource of essay writing topics .

Amanda has an M.S.Ed degree from the University of Pennsylvania in School and Mental Health Counseling and is a National Academy of Sports Medicine Certified Personal Trainer. She has experience writing magazine articles, newspaper articles, SEO-friendly web copy, and blog posts.

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Home — Essay Samples — Nursing & Health — Psychiatry & Mental Health — Depression

Essays About Depression

Depression essay topic examples.

Explore topics like the impact of stigma on depression, compare it across age groups or in literature and media, describe the emotional journey of depression, discuss how education can help, and share personal stories related to it. These essay ideas offer a broad perspective on depression, making it easier to understand and engage with this important subject.

Argumentative Essays

Argumentative essays require you to analyze and present arguments related to depression. Here are some topic examples:

• 1. Argue whether mental health stigma contributes to the prevalence of depression in society.
• 2. Analyze the effectiveness of different treatment approaches for depression, such as therapy versus medication.

Example Introduction Paragraph for an Argumentative Essay: Depression is a pervasive mental health issue that affects millions of individuals worldwide. This essay delves into the complex relationship between mental health stigma and the prevalence of depression in society, examining the barriers to seeking help and the consequences of this stigma.

Example Conclusion Paragraph for an Argumentative Essay: In conclusion, the analysis of mental health stigma's impact on depression underscores the urgent need to challenge and dismantle the stereotypes surrounding mental health. As we reflect on the far-reaching consequences of stigma, we are called to create a society that fosters empathy, understanding, and open dialogue about mental health.

Compare and Contrast Essays

Compare and contrast essays enable you to examine similarities and differences within the context of depression. Consider these topics:

• 1. Compare and contrast the symptoms and risk factors of depression in adolescents and adults.
• 2. Analyze the similarities and differences between the portrayal of depression in literature and its depiction in modern media.

Example Introduction Paragraph for a Compare and Contrast Essay: Depression manifests differently in various age groups and mediums of expression. This essay embarks on a journey to compare and contrast the symptoms and risk factors of depression in adolescents and adults, shedding light on the unique challenges faced by each demographic.

Example Conclusion Paragraph for a Compare and Contrast Essay: In conclusion, the comparison and contrast of depression in adolescents and adults highlight the importance of tailored interventions and support systems. As we contemplate the distinct challenges faced by these age groups, we are reminded of the need for age-appropriate mental health resources and strategies.

Descriptive Essays

Descriptive essays allow you to vividly depict aspects of depression, whether it's the experience of the individual or the societal impact. Here are some topic ideas:

• 1. Describe the emotional rollercoaster of living with depression, highlighting the highs and lows of the experience.
• 2. Paint a detailed portrait of the consequences of untreated depression on an individual's personal and professional life.

Example Introduction Paragraph for a Descriptive Essay: Depression is a complex emotional journey that defies easy characterization. This essay embarks on a descriptive exploration of the emotional rollercoaster that individuals with depression experience, delving into the profound impact it has on their daily lives.

Example Conclusion Paragraph for a Descriptive Essay: In conclusion, the descriptive portrayal of the emotional rollercoaster of depression underscores the need for empathy and support for those grappling with this condition. Through this exploration, we are reminded of the resilience of the human spirit and the importance of compassionate understanding.

Persuasive Essays

Persuasive essays involve arguing a point of view related to depression. Consider these persuasive topics:

• 1. Persuade your readers that incorporating mental health education into the school curriculum can reduce the prevalence of depression among students.
• 2. Argue for or against the idea that employers should prioritize the mental well-being of their employees to combat workplace depression.

Example Introduction Paragraph for a Persuasive Essay: The prevalence of depression underscores the urgent need for proactive measures to address mental health. This persuasive essay asserts that integrating mental health education into the school curriculum can significantly reduce the prevalence of depression among students, offering them the tools to navigate emotional challenges.

Example Conclusion Paragraph for a Persuasive Essay: In conclusion, the persuasive argument for mental health education in schools highlights the potential for early intervention and prevention. As we consider the well-being of future generations, we are called to prioritize mental health education as an essential component of a holistic education system.

Narrative Essays

Narrative essays offer you the opportunity to tell a story or share personal experiences related to depression. Explore these narrative essay topics:

• 1. Narrate a personal experience of overcoming depression or supporting a loved one through their journey.
• 2. Imagine yourself in a fictional scenario where you advocate for mental health awareness and destigmatization on a global scale.

Example Introduction Paragraph for a Narrative Essay: Personal experiences with depression can be transformative and enlightening. This narrative essay delves into a personal journey of overcoming depression, highlighting the challenges faced, the support received, and the lessons learned along the way.

Example Conclusion Paragraph for a Narrative Essay: In conclusion, the narrative of my personal journey through depression reminds us of the resilience of the human spirit and the power of compassion and understanding. As we reflect on our own experiences, we are encouraged to share our stories and contribute to the ongoing conversation about mental health.

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Depression, known as major depressive disorder or clinical depression, is a psychological condition characterized by enduring feelings of sadness and a significant loss of interest in activities. It is a mood disorder that affects a person's emotional state, thoughts, behaviors, and overall well-being.

Its origin can be traced back to ancient civilizations, where melancholia was described as a state of sadness and melancholy. In the 19th century, depression began to be studied more systematically, and terms such as "melancholic depression" and "nervous breakdown" emerged. The understanding and classification of depression have evolved over time. In the early 20th century, Sigmund Freud and other psychoanalysts explored the role of unconscious conflicts in the development of depression. In the mid-20th century, the Diagnostic and Statistical Manual of Mental Disorders (DSM) was established, providing a standardized criteria for diagnosing depressive disorders.

Biological Factors: Genetic predisposition plays a role in depression, as individuals with a family history of the disorder are at a higher risk. Psychological Factors: These may include a history of trauma or abuse, low self-esteem, pessimistic thinking patterns, and a tendency to ruminate on negative thoughts. Environmental Factors: Adverse life events, such as the loss of a loved one, financial difficulties, relationship problems, or chronic stress, can increase the risk of depression. Additionally, living in a socioeconomically disadvantaged area or lacking access to social support can be contributing factors. Health-related Factors: Chronic illnesses, such as cardiovascular disease, diabetes, and chronic pain, are associated with a higher risk of depression. Substance abuse and certain medications can also increase vulnerability to depression. Developmental Factors: Certain life stages, including adolescence and the postpartum period, bring about unique challenges and changes that can contribute to the development of depression.

Depression is characterized by a range of symptoms that affect an individual's emotional, cognitive, and physical well-being. These characteristics can vary in intensity and duration but generally include persistent feelings of sadness, hopelessness, and a loss of interest or pleasure in activities once enjoyed. One prominent characteristic of depression is a noticeable change in mood, which can manifest as a constant feeling of sadness or emptiness. Individuals may also experience a significant decrease or increase in appetite, leading to weight loss or gain. Sleep disturbances, such as insomnia or excessive sleepiness, are common as well. Depression can impact cognitive functioning, causing difficulties in concentration, decision-making, and memory recall. Negative thoughts, self-criticism, and feelings of guilt or worthlessness are also common cognitive symptoms. Furthermore, physical symptoms may arise, including fatigue, low energy levels, and a general lack of motivation. Physical aches and pains, without an apparent medical cause, may also be present.

The treatment of depression typically involves a comprehensive approach that addresses both the physical and psychological aspects of the condition. It is important to note that the most effective treatment may vary for each individual, and a personalized approach is often necessary. One common form of treatment is psychotherapy, which involves talking to a mental health professional to explore and address the underlying causes and triggers of depression. Cognitive-behavioral therapy (CBT) is a widely used approach that helps individuals identify and change negative thought patterns and behaviors associated with depression. In some cases, medication may be prescribed to help manage depressive symptoms. Antidepressant medications work by balancing neurotransmitters in the brain that are associated with mood regulation. It is crucial to work closely with a healthcare provider to find the right medication and dosage that suits an individual's needs. Additionally, lifestyle changes can play a significant role in managing depression. Regular exercise, a balanced diet, sufficient sleep, and stress reduction techniques can all contribute to improving mood and overall well-being. In severe cases of depression, when other treatments have not been effective, electroconvulsive therapy (ECT) may be considered. ECT involves administering controlled electric currents to the brain to induce a brief seizure, which can have a positive impact on depressive symptoms.

1. According to the World Health Organization (WHO), over 264 million people worldwide suffer from depression, making it one of the leading causes of disability globally. 2. Depression can affect people of all ages, including children and adolescents. In fact, the prevalence of depression in young people is increasing, with an estimated 3.3 million adolescents in the United States experiencing at least one major depressive episode in a year. 3. Research has shown that there is a strong link between depression and other physical health conditions. People with depression are more likely to experience chronic pain, cardiovascular diseases, and autoimmune disorders, among other medical conditions.

The topic of depression holds immense significance and should be explored through essays due to its widespread impact on individuals and society as a whole. Understanding and raising awareness about depression is crucial for several reasons. Firstly, depression affects a significant portion of the global population, making it a pressing public health issue. Exploring its causes, symptoms, and treatment options can contribute to better mental health outcomes and improved quality of life for individuals affected by this condition. Additionally, writing an essay about depression can help combat the stigma surrounding mental health. By promoting open discussions and providing accurate information, essays can challenge misconceptions and foster empathy and support for those experiencing depression. Furthermore, studying depression allows for a deeper examination of its complex nature, including its psychological, biological, and sociocultural factors. Lastly, essays on depression can highlight the importance of early detection and intervention, promoting timely help-seeking behaviors and reducing the burden of the condition on individuals and healthcare systems. By shedding light on this critical topic, essays have the potential to educate, inspire action, and contribute to the overall well-being of individuals and society.

1. American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). American Psychiatric Publishing. 2. World Health Organization. (2017). Depression and other common mental disorders: Global health estimates. World Health Organization. 3. Kessler, R. C., Bromet, E. J., & Quinlan, J. (2013). The burden of mental disorders: Global perspectives from the WHO World Mental Health Surveys. Cambridge University Press. 4. Beck, A. T., Rush, A. J., Shaw, B. F., & Emery, G. (1979). Cognitive therapy of depression. Guilford Press. 5. Nierenberg, A. A., & DeCecco, L. M. (2001). Definitions and diagnosis of depression. The Journal of Clinical Psychiatry, 62(Suppl 22), 5-9. 6. Greenberg, P. E., Fournier, A. A., Sisitsky, T., Pike, C. T., & Kessler, R. C. (2015). The economic burden of adults with major depressive disorder in the United States (2005 and 2010). Journal of Clinical Psychiatry, 76(2), 155-162. 7. Cuijpers, P., Berking, M., Andersson, G., Quigley, L., Kleiboer, A., & Dobson, K. S. (2013). A meta-analysis of cognitive-behavioural therapy for adult depression, alone and in comparison with other treatments. Canadian Journal of Psychiatry, 58(7), 376-385. 8. Hirschfeld, R. M. A. (2014). The comorbidity of major depression and anxiety disorders: Recognition and management in primary care. Primary Care Companion for CNS Disorders, 16(2), PCC.13r01611. 9. Rush, A. J., Trivedi, M. H., Wisniewski, S. R., Nierenberg, A. A., Stewart, J. W., Warden, D., ... & Fava, M. (2006). Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: A STAR*D report. American Journal of Psychiatry, 163(11), 1905-1917. 10. Kendler, K. S., Kessler, R. C., Walters, E. E., MacLean, C., Neale, M. C., Heath, A. C., & Eaves, L. J. (1995). Stressful life events, genetic liability, and onset of an episode of major depression in women. American Journal of Psychiatry, 152(6), 833-842.

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Addressing Depression in Your Personal Statement

• college application essays
• essay topic

Did you know 20% of teenagers experience depression before reaching adulthood? It is also during this time that college applicants have to answer the most intimate question in order to gain acceptance at their dream school. What defines you?

While it may feel extremely vulnerable to talk about your experience with depression, don’t let that immediately deter you from choosing it as your personal statement essay topic. Here are 5 examples that may help you approach the topic in an essay:

UC Irvine ‘17

Throughout the past few years, I have gone through depression. The inability to focus not only in school, but also in life, is something I have struggled to overcome. The majority of the time, I am able to successfully distinguish my emotions from my academics because of my overly organized tendencies. At other times, the feelings that come with depression are inevitable. Depression, for me, is hopelessness. My biggest struggle with depression is not being able to see the light at the end of the tunnel; therefore, this way of thinking has caused me to feel unmotivated, alone, and frightened. Because of this, I have spent endless nights contemplating my life till 4 or 5 in the morning, I have no motivation to wake up in the mornings, and I feel pain and grief on a daily basis. Keep reading.

Brittanybea

Uc berkeley ‘19.

On a warm August morning I sat shivering and shaking in the waiting room to my doctor’s office. I had my mother make the appointment but didn’t give her the reason; I’m not even sure I really knew the reason. I just knew something was wrong. The past five years had been all uphill - outwardly, at least. I was doing increasingly well in school, growing more independent, and had greater opportunities at my feet. Inwardly, however, was an entirely different story. Those five years felt like an upbeat movie I was watching while in my own personal prison. I was happy for the characters, even excited for their accomplishments. The problem was that my outward self was a character entirely distinct from the internal me. View full essay.

869749923096609FB

Williams college ‘19.

Perhaps the greatest blessing my parents have ever granted me was the move from our apartment in the Bronx to a two-family home in Queens, two blocks away from a public library. The library had all the boons my young heart could desire: bounties of books, air conditioning in the summer, and sweet solace from a dwelling teeming with the cries of an infant sister, a concept I couldn’t yet fathom. Read more.

When I was younger, people chided me for being pessimistic. It was my sincere belief that there were no rewards to be reaped from a life here on earth. I was bored, unhappy, and apathetic. War, injustice, environmental collapse, the mean thing X said to me the other day-it all made me see the world as a tumultuous and unpleasant place. Continue reading.  

879216135461584FB

Dish soap, pepper, a toothpick, and an empty pie tin. The first materials I ever used to perform a simple experiment in grade school. Looking back that would be the moment I fell in love with science. I can still feel the excitement I felt as I watched as the pepper dart off to the edges of the pie tin as I touched the water with the end of a soap coated toothpick. Though I didn’t have to question how or why the reaction happened, I never stopped wondering. It was then that a passion for science ignited in me. It was a fire in my soul that could never die out. However, I couldn’t have been more wrong. As I grew older, the fire within me began to dim and in the year 2012, it became extinguished; the world as I knew it had ended. View full profile.

While this essay topic helped these students gain acceptances to UC Irvine , UC Berkeley , Williams , Vassar and NYU , it doesn’t mean it will work in the exact same way for you. Brainstorm and think carefully about what you want to write in your personal statement and how you want to share your own, unique story. For more inspiration, AdmitSee has a database of 60,000+ successful college applications files waiting for you! 

About The Author

Frances was born in Hong Kong and received her bachelor’s degree from Georgetown University. She loves super sad drama television, cooking, and reading. Her favorite person on Earth isn’t actually a member of the AdmitSee team - it’s her dog Cooper.

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Your chance of acceptance, your chancing factors, extracurriculars, college essay on depression.

I've been dealing with depression for a while and I feel like it's played a big part in shaping who I am today. Is it a good idea to write my college essay about it? Will admissions officers view it negatively? Any insights would be appreciated.

Writing about depression in your college essay can be a powerful and meaningful way to share your personal experiences and reflect on your growth. However, it's essential to approach the topic thoughtfully and carefully, as mental health is a sensitive subject.

1. Focus on growth and resilience: Instead of primarily describing your struggles with depression, emphasize how you've navigated those challenges and grown as a result. Discuss coping strategies, support systems, and other positive changes you've made that have helped you move forward.

2. Show self-awareness: Demonstrate an understanding of your situation and acknowledge your progress, while still recognizing that recovering from depression is an ongoing journey. This can give college admissions officers a sense of maturity and emotional intelligence on your part.

3. Keep it relevant to your college goals: Connect your experiences with depression to your educational and career aspirations. Perhaps overcoming depression has influenced your choice of major, or it has motivated you to engage in volunteer work or other extracurricular activities.

4. Seek feedback from trusted individuals: Ask someone you trust, like a teacher or counselor, to review your essay and provide input. Their perspectives can ensure that you're discussing depression sensitively and that your essay is appropriate for college admissions officers.

5. Be cautious of oversharing: While it's important to be genuine and authentic, avoid revealing deeply personal or disturbing details about your mental health struggles. Some admissions officers may not be comfortable with this level of disclosure, and it could overshadow your accomplishments and other positive aspects of your application.

In summary, writing about depression in your college essay is a personal choice. If you can present your experiences in a thoughtful, growth-focused manner, and connect your journey to your future goals, then it may be a powerful and effective essay topic. However, always consider seeking feedback from trusted individuals to ensure you are addressing the topic appropriately.

About CollegeVine’s Expert FAQ

CollegeVine’s Q&A seeks to offer informed perspectives on commonly asked admissions questions. Every answer is refined and validated by our team of admissions experts to ensure it resonates with trusted knowledge in the field.

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My battle with depression and the two things it taught me

I’ve spent a decade slipping in and out of depression, but thanks to the right medicine and loving people, I’m back to being me again

I t’s often said that depression isn’t about feeling sad. It’s part of it, of course, but to compare the life-sapping melancholy of depression to normal sadness is like comparing a paper cut to an amputation. Sadness is a healthy part of every life. Depression progressively eats away your whole being from the inside. It’s with you when you wake up in the morning, telling you there’s nothing or anyone to get up for. It’s with you when the phone rings and you’re too frightened to answer it.

It’s with you when you look into the eyes of those you love, and your eyes prick with tears as you try, and fail, to remember how to love them. It’s with you as you search within for those now eroded things that once made you who you were: your interests, your creativity, your inquisitiveness, your humour, your warmth. And it’s with you as you wake terrified from each nightmare and pace the house, thinking frantically of how you can escape your poisoned life; escape the embrace of the demon that is eating away your mind like a slow drip of acid.

And always, the biggest stigma comes from yourself. You blame yourself for the illness that you can only dimly see.

So why was I depressed? The simple answer is that I don’t know. There was no single factor or trigger that plunged me into it. I’ve turned over many possibilities in my mind. But the best I can conclude is that depression can happen to anyone. I thought I was strong enough to resist it, but I was wrong. That attitude probably explains why I suffered such a serious episode – I resisted seeking help until it was nearly too late.

Let me take you back to 1996. I’d just begun my final year at university and had recently visited my doctor to complain of feeling low. He immediately put me on an antidepressant, and I got down to the business of getting my degree. The pills took a few weeks to work, but the effects were remarkable. Too remarkable. About six weeks in I was leaping from my bed each morning with a vigour and enthusiasm I had never experienced, at least not since early childhood. I started churning out first-class essays and my mind began to make connections with an ease that it had never done before.

The only problem was that the drug did much more. It broke down any fragile sense I had of social appropriateness. I’d frequently say ridiculous and painful things to people I had no right to say them to. So, after a few months, I decided to stop the pills. I ended them abruptly, not realising how foolish that was – and spent a week or two experiencing brain zaps and vertigo. But it was worth it. I still felt good, my mind was still productive, and I regained my sense of social niceties and appropriate behaviour.

I had hoped that was my last brush with mental health problems, but it was not to be.

On reflection, I realise I have spent over a decade dipping in and out of minor bouts of depression – each one slightly worse than the last.

Last spring I was in the grip of depression again. I couldn’t work effectively. I couldn’t earn the income I needed. I began retreating to the safety of my bed – using sleep to escape myself and my exhausted and joyless existence.

So I returned to the doctor and told her about it. It was warm, and I was wearing a cardigan. “I think we should test your thyroid,” she said. “But an antidepressant might help in the meantime.” And here I realised, for all my distaste for the stigmatisation of mental illness, that I stigmatised it in myself. I found myself hoping my thyroid was bust. Tell someone your thyroid’s not working, and they’ll understand and happily wait for you to recover. Tell them you’re depressed, and they might think you’re weak, or lazy, or making it up. I really wanted it to be my thyroid. But, of course, when the blood test came back, it wasn’t. I was depressed.

So I took the antidepressant. And it worked. To begin with. A month into the course, the poisonous cloud began to lift and I even felt my creativity and urge to write begin to return for the first time in years. Not great literature, but fun to write and enjoyed by my friends on social media. And tellingly, my wife said: “You’re becoming more like the person I first met.”

It was a turning point. The drug had given me objectivity about my illness, made me view it for what it was. This was when I realised I had been going through cycles of depression for years. It was a process of gradual erosion, almost impossible to spot while you were experiencing it. But the effects of the drug didn’t last. By September I was both deeply depressed and increasingly angry, behaving erratically and feeling endlessly paranoid.

My wife threatened to frog march me back to the doctor, so I made an appointment and was given another drug. The effects have been miraculous. Nearly two months in and I can feel the old me re-emerging. My engagement and interest is flooding back. I’m back at work and I’m producing copy my clients really love. Only eight weeks ago, the very idea that I would be sitting at home tapping out a blog post of this length on my phone would have made me grunt derisively. But that is what has happened, and I am truly grateful to all those who love and care for me for pushing me along to this stage.

And now, I need to get back to work. Depression may start for no definable reason, but it leaves a growing trail of problems in its wake. The more ill I got, the less work I could do, the more savings I spent and the larger the piles of unpaid bills became. But now I can start to tackle these things.

If you still attach stigma to people with mental illness, please remember two things. One, it could easily happen to you. And two, no one stigmatises their illness more than the people who suffer from it. Reach out to them.

• Mental health

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16 Personal Essays About Mental Health Worth Reading

Here are some of the most moving and illuminating essays published on BuzzFeed about mental illness, wellness, and the way our minds work.

BuzzFeed Staff

1. My Best Friend Saved Me When I Attempted Suicide, But I Didn’t Save Her — Drusilla Moorhouse

"I was serious about killing myself. My best friend wasn’t — but she’s the one who’s dead."

2. Life Is What Happens While You’re Googling Symptoms Of Cancer — Ramona Emerson

"After a lifetime of hypochondria, I was finally diagnosed with my very own medical condition. And maybe, in a weird way, it’s made me less afraid to die."

3. How I Learned To Be OK With Feeling Sad — Mac McClelland

"It wasn’t easy, or cheap."

4. Who Gets To Be The “Good Schizophrenic”? — Esmé Weijun Wang

"When you’re labeled as crazy, the “right” kind of diagnosis could mean the difference between a productive life and a life sentence."

5. Why Do I Miss Being Bipolar? — Sasha Chapin

"The medication I take to treat my bipolar disorder works perfectly. Sometimes I wish it didn’t."

6. What My Best Friend And I Didn’t Learn About Loss — Zan Romanoff

"When my closest friend’s first baby was stillborn, we navigated through depression and grief together."

7. I Can’t Live Without Fear, But I Can Learn To Be OK With It — Arianna Rebolini

"I’ve become obsessively afraid that the people I love will die. Now I have to teach myself how to be OK with that."

8. What It’s Like Having PPD As A Black Woman — Tyrese Coleman

"It took me two years to even acknowledge I’d been depressed after the birth of my twin sons. I wonder how much it had to do with the way I had been taught to be strong."

9. Notes On An Eating Disorder — Larissa Pham

"I still tell my friends I am in recovery so they will hold me accountable."

10. What Comedy Taught Me About My Mental Illness — Kate Lindstedt

"I didn’t expect it, but stand-up comedy has given me the freedom to talk about depression and anxiety on my own terms."

11. The Night I Spoke Up About My #BlackSuicide — Terrell J. Starr

"My entire life was shaped by violence, so I wanted to end it violently. But I didn’t — thanks to overcoming the stigma surrounding African-Americans and depression, and to building a community on Twitter."

12. Knitting Myself Back Together — Alanna Okun

"The best way I’ve found to fight my anxiety is with a pair of knitting needles."

13. I Started Therapy So I Could Take Better Care Of Myself — Matt Ortile

"I’d known for a while that I needed to see a therapist. It wasn’t until I felt like I could do without help that I finally sought it."

14. I’m Mending My Broken Relationship With Food — Anita Badejo

"After a lifetime struggling with disordered eating, I’m still figuring out how to have a healthy relationship with my body and what I feed it."

15. I Found Love In A Hopeless Mess — Kate Conger

"Dehoarding my partner’s childhood home gave me a way to understand his mother, but I’m still not sure how to live with the habit he’s inherited."

16. When Taking Anxiety Medication Is A Revolutionary Act — Tracy Clayton

"I had to learn how to love myself enough to take care of myself. It wasn’t easy."

Topics in this article

• Mental Health

327 Depression Essay Titles & Examples

When choosing a title about depression, you have to remain mindful since this is a sensitive subject. This is why our experts have listed 177 depression essay topics to help you get started.

🌧️ How to Write a Depression Essay: Do’s and Don’ts

🏆 unique titles about depression, 🥇 most interesting depression title ideas, 📌 good titles for depression essay, ✅ simple & easy depression essay titles, 🎓 interesting topics to write about depression, 📑 good research topics about depression.

• ❓ Research Questions for a Depression Essay

Depression is a disorder characterized by prolonged periods of sadness and loss of interest in life. The symptoms include irritability, insomnia, anxiety, and trouble concentrating. This disorder can produce physical problems, self-esteem issues, and general stress in a person’s life. Difficult life events and trauma are typical causes of depression. Want to find out more? Check out our compilation below.

A depression essay is an important assignment that will help you to explore the subject and its impact on people. Writing this type of paper may seem challenging at first, but there are some secrets that will make achieving a high grade much easier. Check below for a list of do’s and don’ts to get started!

DO select a narrow topic. Before starting writing, define the subject of the paper, and write down some possible titles. This will help you to focus your thoughts instead of offering generic information that can easily be found on Wikipedia. Consider writing about a particular population or about the consequences of depression. For example, a teenage depression essay could earn you excellent marks! If you find this step challenging, try searching for depression essay topics online. This will surely give you some inspiration.

DON’T copy from peers or other students. Today, tutors are usually aware of the power of the Internet and will check your paper for plagiarism. Hence, if you copy information from other depression essays, you could lose a lot of marks. You could search for depression essay titles or sample papers online, but avoid copying any details from these sources.

DO your research before starting. High-quality research is crucial when you write essays on mental health issues. There are plenty of online resources that could help you, including Google Scholar, PubMed, and others. To find relevant scientific articles, search for your primary and secondary topics of interest. Then filter results by relevance, publication date, and access type. This will help you to identify sources that you can view online and use to support your ideas.

DON’T rely on unverified sources. This is a crucial mistake many students make that usually results in failing the paper. Sources that are not academic, such as websites, blogs, and Wiki pages, may contain false or outdated information. Some exceptions are official publications and web pages of medical organizations, such as the CDC, APA, and the World Health Organization.

DO consider related health issues. Depression is often associated with other mental or physical health issues, so you should reflect on this in your paper. Some examples of problems related to depression are suicide, self-harm, eating disorders, and panic attack disorder. To show your in-depth understanding of the issue, you could write a depression and anxiety essay that shows the relationship between the two. Alternatively, you can devote one or two paragraphs to examining the prevalence of other mental health problems in people with depression.

DON’T include personal opinions and experiences unless required. A good essay on the subject of depression should be focused and objective. Hence, you should rely on research rather than on your understanding of the theme. For example, if you have to answer the question “What is depression?” look for scientific articles or official publications that contain the definition rather than trying to explain it in your own words.

DON’T forget about structure. The structure of your essay helps to present arguments or points logically, thus assisting the reader in making sense of the information. A good thing to do is to write a depression essay outline before you start the paper. You should list your key points supported by relevant depression quotes from academic publications. Follow the outline carefully to avoid gaps and inconsistencies.

Use these do’s and don’ts, and you will be able to write an excellent paper on depression! If you want to see more tips and tricks that will help you elevate your writing, look around our website!

• Understanding Teen Depression Impacts of depression on teenagers Depression is characterized by several effects; however, most of them impact negatively to the teens. For instance, a considerable percentage of teens use extra-curriculum activities such as sports and games, […]
• Beck Depression Inventory, Its History and Benefits Therefore, the detection of depression at its early stage, the evaluation of the risks, and the definition of the level of depression are the main goals.
• Depression and Grief in the “Ordinary People” Film At the end of the film, he is healed and ready to forgive his mother and stop blaming himself. I believe that the relationship between Conrad and his therapist, Dr.
• Report Writing About Depression There is concrete evidence that many people in Australia tend to believe that depression is the cause of all suicide deaths in the world, but this not true.
• Cognitive Behavioral Therapy in Treating Depression CBT works on the principle that positive thoughts and behaviour heralds positive moods and this is something that can be learned; therefore, by learning to think and behave positively, someone may substitute negative thoughts with […]
• Social Networking and Depression The findings of the study confirmed that once an individual engages in social networking, his or her feeling of safety goes down and depression mood emerges meaning that a correlation between depression and social networking […]
• The Problem of Childhood Depression Thus, it is essential to explore the reasons for the disease and possible ways to treat depression in kids. In kids, the prevention of depression is fundamental to understanding the cause of the poor mood […]
• Depression in the Lens of History and Humanities In terms of history, this paper analyzes the origin of depression and the progress made over the years in finding treatment and preventive mechanisms.
• Case Study of Depression and Mental Pressure Alison believes that her illness is severe and taking a toll all the time, and the environment is worsening the condition.
• Depression, Grief, Loss in “Ordinary People” Film The coach is curious to know Conrad’s experiences at the hospital and the use of ECT. Towards the end of the film, Conrad reveals to the therapist that he feels guilty about his brother’s death.
• The Difference Between Art Deco and Depression Modern Design By and whole, Art Deco and Depression differ in their characteristics and their meanings as they bring unlike messages to the viewers.
• Obesity Co-Occurring With Depression The assessment will identify the patient with the two conditions, address the existing literature on the issue, examine how patients are affected by organizational and governmental policies, and propose strategies to improve the patient experience.
• Depression: A Cognitive Perspective Therefore, the cause of depression on this line may be a real shortage of skills, accompanied by negative self-evaluation because the individual is more likely to see the negative aspects or the skills he lacks […]
• Emotional Wellness: The Issue of Depression Through Different Lenses As for the humanities lens, the increasing prevalence of depression causes the institution of religion to incorporate the issue into major confessions’ mindsets and messages.
• Anxiety and Depression Among College Students The central hypothesis for this study is that college students have a higher rate of anxiety and depression. Some of the materials to be used in the study will include pencils, papers, and tests.
• Biological and Social-Cognitive Perspectives on Depression The social-cognitive perspective states that the disorder’s development is influenced by the events in the patient’s life and their way of thinking.
• Depression as a Psychological Disorder Summarizing and evaluating the information that trusted journals have published on the topic of depression might help create a well-rounded review of the condition and the scientific community’s understanding of it.
• Depression and Melancholia Expressed by Hamlet The paper will not attempt and sketch the way the signs or symptoms of depression/melancholia play a part in the way Shakespeare’s period or culture concerning depression/melancholia, but in its place portrays the way particular […]
• Depression and Its Causes in the Modern Society The higher instances of depression among women can be explained using a number of reasons including the lifestyle of the modern woman and her role in the society.
• NICE Guidelines for Depression Management: Project Proposal This topic is of importance for VEGA because the center does not employ any specific depression management guidelines.
• Depression in Older Adults The understanding and modification of the contributions of these factors is the ultimate goal of the clinicians who engage in the treatment of depression.
• PICO Analysis of Depression In other words, the causes of the given mental disorder can highly vary, and there is no sufficient evidence to point out a primary factor that triggers depression.
• Depression Among University Students The greatest majority of the affected individuals in different universities will be unable to take good care of their bodies and living rooms.
• Teenage Depression: Psychology-Based Treatment This finding underlines the need to interrogate the issue of depression’s ontology and epistemology. Hence, there is the need to have an elaborate and comprehensive policy for addressing teenage depression.
• Depression Symptoms and Cognitive Behavior Therapy The tone of the article is informative and objective, throughout the text the authors maintain an academic and scientific mood. The structure of the article is well organized and easy to read.
• Proposal on Depression in Middle-Aged Women By understand the aspect of unhappiness among the young women; it will be easier for the healthcare institutions to formulate effective and appropriate approaches to reduce the menace in the society.
• Biological Psychology: Lesion Studies and Depression Detection The purpose of this article is to share the research findings and discussion on the new methodological developments of Lesion studies.
• Using AI to Diagnose and Treat Depression One of the main features of AI is the ability to machine learning, that is, to use data from past experiences to learn and modify algorithms in the future.
• Artificial Intelligence Bot for Depression By increasing the availability and accessibility of mental health services, these technologies may also contribute to the development of cognitive science practices in Malaysia.
• COVID-Related Depression: Lingering Signs of Depression The purpose of the article is to depict the research in a more approachable way, while the latter accentuates the importance of various factors and flaws of the results. While the former is more simplified, […]
• Depression and Anxiety Among African Americans Finally, it should be insightful to understand the attitudes of friends and family members, so 5 additional interviews will be conducted with Black and White persons not having the identified mental conditions. The selected mental […]
• Depression in Dialysis Patients: Treatment and Management If I were to conduct experimental research about the treatment and management of depression in dialysis patients, I would focus on finding the most effective and safe medication for the condition among adults.
• The Serotonin Theory of Depression by Moncrieff et al. The serotonin theory of depression is closely related to antidepressants since the advent of SSRIs played a significant role in the popularization of the theory.
• Avery’s Depression in “The Flick” Play by Baker The emotional and mental state of Avery, the only African-American character out of the three, is fairly obvious from the get-go when asked about why he is so depressed, the answer is: “Um.
• Depression: A Quantitative-Qualitative Analysis A decision tree can be used due to the nature of the research question or hypothesis in place, the measurement of the dependent or research variable, the number of groups or independent variable levels, and […]
• Depression Detection Tests Analysis The problem of the abundance of psychological tests leads to the need to compare multiple testing options for indicators of their purpose, features, and interpretations of the evaluation and validity.
• Nursing Care for Patients With COVID-19 & Depression The significance of the selected problem contributed to the emergence of numerous research works devoted to the issue. This approach to choosing individuals guaranteed the increased credibility of findings and provided the authors with the […]
• 16 Personality Factors Test for Depression Patient Pablos results, it is necessary to understand the interaction and pattern of the scores of the primary factors. A combination of high Apprehension and high Self-Reliance is a pattern describing a tendency to isolate oneself.
• Depression in a 30-Year-Old Female Client In the given case, it would be useful to identify the patterns in Alex’s relationships and reconsider her responses to her partner.
• Using the Neuman Model in the Early Diagnosis of Depression In the history of the academic development of nursing theories, there are a variety of iconic figures who have made significant contributions to the evolution of the discipline: one of them is Betty Neuman.
• Depression in Primary Care: Screening and Diagnosis The clinical topics for this research are the incidence of depression in young adults and how to diagnose this disorder early in the primary care setting using screening tools such as PHQ9.
• Major Depression and Cognitive Behavior Therapy Since the intervention had no significant effect on Lola, the paper will explore the physical health implication of anxiolytics and antidepressants in adolescents, including the teaching strategies that nurses can utilize on consumers to recognize […]
• Jungian Psychotherapy for Depression and Anxiety They work as a pizza delivery man in their spare time from scientific activities, and their parents also send them a small amount of money every month.S.migrated to New York not only to get an […]
• COVID-19 and Depression: The Impact of Nursing Care and Technology Nevertheless, combatting depression is a crucial step in posing positive achievements to recover from mental and physical wellness caused by COVID-19.
• Depression Disorder Intervention The researchers evaluated the socioemotional signs of mental illnesses in a sample of diagnostically referred adolescents with clinical depression required to undergo regular cognitive behavioral therapy in a medical setting.
• Financial Difficulties in Childhood and Adult Depression in Europe The authors found that the existence of closer ties between the catalyst of depression and the person suffering from depression leads to worse consequences.
• Activity During Pregnancy and Postpartum Depression Studies have shown that women’s mood and cardiorespiratory fitness improve when they engage in moderate-intensity physical activity in the weeks and months after giving birth to a child.
• Clinical Depression: Causes and Development Therefore, according to Aaron Beck, the causes and development of depression can be explained through the concepts of schema and negative cognitive triad.
• Aspects of Working With Depression It also contributes to the maintenance and rooting of a bad mood, as the patient has sad thoughts due to the fact that the usual does not cause satisfaction.
• Depression Among Nurses in COVID-19 Wards The findings are of great significance to researchers and governments and can indicate the prevalence of anxiety and depression among nurses working in COVID-19 wards in the North-East of England during the pandemic.
• Depression Associated With Sleep Disorders Y, Chang, C. Consequently, it directly affects the manifestation of obstructive sleep apnea, restless leg syndrome, and periodic limb movement disorder in people with depression.
• Depression in a 25-Year-Old Male Patient Moreover, a person in depression complains of the slowness in mental processes, notes the oppression of instincts, the loss of the instinct of self-preservation, and the lack of the ability to enjoy life.
• Aspects and Manifestation of Depression Although, symptoms of depression in young people, in contrast to older adults, are described by psychomotor agitation or lethargy, fatigue, and loss of energy.
• Complementary Therapy for Postpartum Depression in Primary Care Thus, the woman faced frustration and sadness, preventing her from taking good care of the child, and the lack of support led to the emergence of concerns similar to those in the past.
• Depression and Anxiety Clinical Case Many of the factors come from the background and life experiences of the patient. The client then had a chance to reflect on the results and think of the possible alternative thoughts.
• Uncontrolled Type 2 Diabetes and Depression Treatment The data synthesis demonstrates that carefully chosen depression and anxiety treatment is likely to result in better A1C outcomes for the patient on the condition that the treatment is regular and convenient for the patients.
• Technology to Fight Postpartum Depression in African American Women I would like to introduce the app “Peanut” the social network designed to help and unite women exclusively, as a technology aimed at fighting postpartum depression in African American Women.
• Complementary Therapy in Treatment of Depression Such practices lower the general level of anxiety and remove the high risks of manifestation of states of abulia, that is, clinical lack of will and acute depression.
• Social Determinants of Health and Depression Among African American Adults The article “Social Determinants of Health and Depression among African American Adults: A Scoping Review of Current Research” examines the current research on the relationship between social determinants of health and depression among African American […]
• Outcomes Exercise Has on Depression for People Between 45-55 Years According to the WHO, the rate of depression in the U.S.was 31. 5% as of October 2021, with the majority of the victims being adults aged between 45 and 55 years.
• The Postpartum Depression in Afro-Americans Policy The distribution of the funds is managed and administered on the state level. Minnesota and Maryland focused on passing the legislation regulating the adoption of Medicaid in 2013.
• Depression Among the Medicare Population in Maryland The statistics about the prevalence and comorbidity rates of depression are provided from the Medicare Chronic Conditions Dashboard and are portrayed in the table included in the paper.
• Depression as Public Health Population-Based Issue In regard to particular races and ethnicities, CDC provided the following breakdown of female breast cancer cases and deaths: White women: 128 new cases and 20 deaths per 100.
• Managing Mental Health Medications for Depression and its Ethical Contradiction The second objective is to discover ethical contradictions in such treatment for people of various cultures and how different people perceive the disorder and react to the medication.
• Aspects of Depression and Obesity In some cases, people with mild to severe depression choose not to seek professional care and instead try to overcome their depression with self-help or the support of family and friends.
• Antidepressant Treatment of Adolescent Depression At the same time, scientists evidenced that in the case of negative exposure to stress and depression, the human organism diminishes BDNF expression in the hippocampus.
• Online Peer Support Groups for Depression and Anxiety Disorder The main objective of peer support groups is connecting people with the same life experiences and challenges to share and support each other in healing and recovery.
• Depression in Adolescence and Treatment Approaches The age of adolescence, commonly referred to as children aged 10-19, is characterized by a variety of changes to one’s physical and mental health, as the child undergoes several stages of adjustment to the environment […]
• Emotional Encounter With a Patient With Major Depression Disorder I shared this idea with him and was trying to create the treatment plan, sharing some general thoughts on the issue.
• Childhood Depression in Sub-Saharan Africa According to Sterling et al, depression in early childhood places a significant load on individuals, relatives, and society by increasing hospitalization and fatality and negatively impacting the quality of life during periods of severe depression.
• Anxiety and Depression: The Case Study As he himself explained, he is not used to positive affirmation due to low self-esteem, and his family experiences also point to the fact that he was not comforted often as a child.
• Breastfeeding and Risk of Postpartum Depression The primary goal of the research conducted by Islam et al.was to analyze the correlation between exclusive breastfeeding and the risk of postpartum depression among new mothers.
• Nursing Intervention in Case of Severe Depression The patient was laid off from work and went through a divorce in the year. This led to a change in prescribed medications, and the patient was put on tricyclic anti-depressants.
• Screening for Depression in Acute Care The literature review provides EB analysis for the topic of depression to identify the need for an appropriate screening tool in addition to the PHQ-9 in the assessment evaluation process.
• Social Media Use and the Risk of Depression Thapa and Subedi explain that the reason for the development of depressive symptoms is the lack of face to face conversation and the development of perceived isolation. Is there a relationship between social media use […]
• Depression in the Field of a Healthcare Administrator According to Davey and Harrison, the most challenging part of healthcare administration in terms of depression is the presence of distorted views, shaped by patients’ thoughts.
• The Treatment of Adolescents With Depression While treating a teenager with depression, it is important to maintain the link between the cause of the mental illness’ progression and the treatment.
• Depression in the Black Community The speaker said that her counselor was culturally sensitive, which presumes that regardless of the race one belongs to, a specialist must value their background.
• Loneliness and Depression During COVID-19 While the article discusses the prevalence of loneliness and depression among young people, I agree that young people may be more subject to mental health problems than other population groups, but I do not agree […]
• Depression Screening in the Acute Setting Hence, it is possible to develop a policy recommending the use of the PHQ-9, such as the EBDST, in the acute setting.
• Ketamine for Treatment-Resistant Depression: Neurobiology and Applications It is known that a violation of the functions of the serotonergic pathways leads to various mental deviations, the most typical of which is clinical depression.
• Treating Obesity Co-Occurring With Depression In most cases, the efficiency of obesity treatment is relatively low and commonly leads to the appearance of a comorbid mental health disorder depression.
• Treadmill Exercise Ameliorates Social Isolation-Induced Depression The groups included: the social isolation group, the control group, and the exercise and social isolation and exercise group. In the treadmill exercise protocol, the rat pups ran on the treadmill once a day for […]
• Depression and Anxiety Among Chronic Pain Patients The researchers used The Depression Module of the Patient Health Questionnaire and the Generalized Anxiety Disorder Scale to interview participants, evaluate their answers, and conduct the study.
• Postpartum Depression in African American Women As far as African American women are concerned, the issue becomes even more complex due to several reasons: the stigma associated with the mental health of African American women and the mental health complications that […]
• The Depression Construct and Instrument Analysis For the therapist, this scaling allows to assess the general picture of the patient’s psychological state and obtain a result that is suitable for measurement.
• The Effects of Cognitive Behavioral Therapy (CBT) on Depression in Adults Introduction It is hard to disagree that there is a vast number of mental disorders that prevent people from leading their normal lives and are quite challenging to treat. One such psychological condition is depression (Li et al., 2020). Since there is a social stigma of depression, and some of its symptoms are similar to […]
• Stress and Depression Among Nursing Students The study aims to determine how different the manifestations of stress and depression are among American nursing students compared to students of other disciplines and what supports nursing students in continuing their education.
• Depression in Diabetes Patients The presence of depression concomitant to diabetes mellitus prevents the adaptation of the patient and negatively affects the course of the underlying disease.
• Depression among Homosexual Males The literature used for the research on the paper aims to overview depression among homosexual males and describe the role of the nurse and practices based on the Recovery Model throughout the depression.
• “What the Depression Did to People” by Edward Robb Ellis Nevertheless, the way the facts are grouped and delivered could be conducive to students’ ability to develop a clearer picture of the catastrophic downturn’s influences on the nation’s and the poor population’s mentalities.
• Economic Inequality During COVID-19: Correlation With Depression and Addiction Thus, during the pandemic, people with lower incomes experienced depression and increased their addictive behaviors to cope with the stress of COVID-19.
• Depression in the Black and Minority Ethnic Groups The third sector of the economy includes all non-governmental, non-profit, voluntary, philanthropic, and charitable organizations and social enterprises specializing in various types of activities, which did not find a place in either the public or […]
• A Description on the Topic Screening Depression If there is the implementation of evidence-based care, a reduction in the proportion of disability for patients with depression would be expected. A proposal was written describing the need for screening depression patients of nearly […]
• “Disclosure of Symptoms of Postnatal Depression, …” by Carolyn Chew-Graham Critique In light of hypothesizing the research question, the researchers suggest that health practitioners have the ability to create a conducive environment for the disclosure of information.
• Depression – Psychotherapeutic Treatment Taking into account the fact that the specialist is not able to prescribe the medicine or a sort of treatment if he/she is not sure in the positive effect it might have on the health […]
• Depression as a Major Health Issue The purpose of the study was to examine the implications of cognitive behavior approaches for depression in old women receiving health care in different facilities.
• Effective Ways to Address Anxiety and Depression Looking deep into the roots of the problem will provide a vast and detailed vision of it, and will help to develop ways to enhance the disorders.
• Einstepam: The Treatment of Depression The treatment of depression has greatly revolutionized since the development of tricyclic antidepressants and monoamine oxidase inhibitors in the 1950s. In the brain, it inhibits the NMDA receptors and isoforms of NOS.
• The Potential of Psilocybin in Treating Depression First of all, it is essential to understand the general effects of psilocybin on the brain that are present in the current literature.
• Depression Among High School Students The major problem surrounding depression among adolescents is that they are rarely diagnosed in time and therefore do not receive treatment they need.
• Depression: Diagnostics, Prevention and Treatment Constant communication with the patient and their relatives, purposeful questioning of the patient, special scales and tests, active observation of the patient’s appearance and behavior are the steps in the nursing diagnosis of depression.
• Depression and Anxiety Intervention Plan John’s Wort to intervene for her condition together with the prescribed anti-depressant drugs, I would advise and educate her on the drug-to-drug relations, and the various complications brought about by combining St. Conducting proper patient […]
• Depression and Generalized Anxiety Disorder Therapy On the other hand, behavioral therapy relies on the assumption that “both abnormal behavior and normal behavior are learned”. The two approaches are thus highly complementary, as while humanistic therapy aims at perceiving and resolving […]
• The Use of Psychedelic Drugs in Treating Depression This study aims to establish whether depressive patients can significantly benefit from psilocybin without substantial side effects like in the case of other psychedelic drugs.
• Postpartum Depression Among the Low-Income U.S. Mothers Mothers who take part in the programs develop skills and knowledge to use the existing social entities to ensure that they protect themselves from the undesirable consequences associated with the PPD and other related psychological […]
• The Beck Depression Contrast (BDI) The second difference between the two modes of the BDI is in the methodology of conducting the survey. This is where the interviewer first gets the history of the patient to try and get the […]
• Depression: Description, Symptoms and Diagnosis, Prognosis and Treatment A diagnosis is made in situations where the symptoms persist for at least two weeks and lead to a change in the individual’s level of functioning.
• Psychedelic Drugs and Their Effects on Anxiety and Depression The participants must also be willing to remain in the study for the duration of the experiments and consent to the drugs’ use.
• VEGA Medical Center: The Quality of Depression Management This presentation is going to provide an overview of a project dedicated to the implementation of NICE guidelines at the VEGA Medical Center.
• Anxiety and Depression in Hispanic Youth in Monmouth County Therefore, the Health Project in Monmouth County will help Hispanic children and adolescents between the ages of 10 and 19 to cope with anxiety and depression through behavioral therapy.
• Anxiety Disorders and Depression In her case, anxiety made her feel that she needed to do more, and everything needed to be perfect. She noted that the background of her depression and anxiety disorders was her family.
• Clinical Case Report: Depression It is possible to assume that being in close contact with a person who has depression also increases the probability of experiencing its symptoms.
• Interventions for Treating Depression after Stroke Inherently, the link between depression and stroke can be analyzed on the basis of post-stroke depression that is identified as the major neuropsychiatric corollary of stroke.
• Depression: The Implications and Challenges in Managing the Illness At home, these people lack interest in their family and are not be able to enjoy the shared activities and company of the family.
• Expression Symptoms of Depression A major finding of the critique is that although the research method and design are appropriate to this type of study, the results may be speculative in their validity and reliability as the researchers used […]
• Researching Postnatal Depression Health professionals suggest that the fluctuations in the level of hormones cause changes in the chemical composition of the brain. The researcher has stated that the sample was selected from the general practitioners and health […]
• The Older Women With Depression Living in Long-Term Care The researchers used the probability-sampling method to select the institutions that were included in the study. The health care professionals working in the nursing homes were interviewed to ascertain the diagnosis of depression as well […]
• Medical Evaluation: 82-Year-Old Patient With Depression Her extreme level of weakness unfolded when the patient admitted that she lacked the strength to stand on her feet and to head back to her sleeping bed on a disastrous night.Mrs.
• Depression in Adults: Community Health Needs The challenge of depression in the elderly is the recognition of signs and symptoms or the frequent underreporting of the symptoms of depression in adults over the age of 65.
• The Discussion about Depression in Older Patients Depression is often identified as the most prevalent psychiatric disorder in the elderly and is usually determined by symptoms that belong to somatic, affective, and cognitive categories.
• Depression in Older People in Australia Although a good number of depressed elderly patients aspire to play an active role in the treatment decision-making process, some prefer to delegate this role to their doctors.
• In-Vitro Fertilization and Postpartum Depression The research was conducted through based on professional information sources and statistical data collected from the research study used to further validate the evidence and outcome of this study.
• Depression: Screening and Diagnosis What he tries to do is to live a day and observe the changes that occur around. What do you do to change your attitude to life?
• Depression in Australia. Evaluation of Different Factors In attempts to identify the biological causes of depression, the researchers focus on the analysis of brain functioning, chemical mediators, their correlations with the neurologic centers in the brain, and impact on the limbic system […]
• Mental Health Paper: Depression The prevalence of mental health conditions has been the subject of many studies, with most of these highlighting the increase in these illnesses.
• The Two Hit Model of Cytokine-Induced-Depression The association between IL-6 polymorphism and reduced risk of depressive symptoms confirms the role of the inflammatory response system in the pathophysiology of IFN-alpha-induced depression.
• Ante-Partum & Postpartum Exposure to Maternal Depression The researchers engaged in the research work on this particular study topic by approaching it on the basis of maternal behavior and circumstances, as they connect to depressive conditions in their own lives and the […]
• Depression in Australia, How Treat This Disorder According to The World Health Organization, depression is defined as a disorder in the mental health system that is presented with feelings of guiltiness, low concentration, and a decrease in the need for sleep.
• Steroid Use and Teen Depression In this manner, the researcher will be in a position to determine which of the two indicators is strongest, and then later, the indicators can be narrowed down to the most basic and relevant.
• Depression Among Minority Groups Mental disorders are among the major problems facing the health sector in America and across the world in the contemporary society.
• Aspects and Definition of Depression: Psychiatry This is the personal counseling of a patient with the doctor, and it is one of the very best processes. In the case of a physician dealing with a mental patient, the most preferable way […]
• Dual Illness – Depression and Alcohol Abuse The intention of the research paper is to assess if indeed there is an association between alcoholism as manifested by Jackson, and a case of depression.
• Depression and Paranoid Personality Disorder Bainbridge include: The analysis of paranoia and anxiety caused by substance abuse reveals that the diagnosis can be correct based on the symptoms, but the long-lasting nature of the symptoms rejects this diagnosis in favor […]
• Antidepressant Drugs for Depression or Dysthymia These are the newer form of antidepressant that are based on both the principle of serotonin reuptake prevention and norepinephrine action.
• The Relationship of Type 2 Diabetes and Depression Type 2 diabetes is generally recognized as an imbalance between insulin sensitivity and beta cell function We have chosen a rural area in Wisconsin where we can focus our study and select a group of […]
• Teenage Depression and Alcoholism There also has been a demonstrated connection between alcoholism and depression in all ages; as such, people engage in alcoholism as a method of self medication to dull the feelings of depression, hopelessness and lack […]
• “Relationships of Problematic Internet Use With Depression”: Study Strengths and Weaknesses One of the study strengths is that the subject selection process is excellently and well-designed, where the subjects represent the study sample, in general.
• Depression Treatment: Biopsychosocial Theory More to the point, the roles of nurses, an interprofessional team, and the patient’s family will be examined regarding the improvement of Majorie’s health condition.
• Postpartum Depression and Its Impact on Infants The goal of this research was “to investigate the prevalence of maternal depressive symptoms at 5 and 9 months postpartum in a low-income and predominantly Hispanic sample, and evaluate the impact on infant weight gain, […]
• Postpartum Depression: Statistics and Methods of Diagnosis The incorporation of the screening tools into the existing electronic medical support system has proved to lead to positive outcomes for both mothers and children.
• Comorbidity of Depression and Pain It is also known that dysregulation of 5-HT receptors in the brain is directly related to the development of depression and the regulation of the effects of substance P, glutamate, GABA and other pain mediators. […]
• Hallucinations and Geriatric Depression Intervention Sandy has asserted further that the cleaners at the residence have been giving him the wrong medication since they are conspiring to end his life with the FBI.Mr.
• Changes in Approaches to the Treatment of Depression Over the Past Decade In spite of the fact that over the past decade many approaches to the treatment of depression remained the same, a lot of new methods appeared and replaced some old ones due to the development […]
• Management of Treatment-Resistant Depression The significance of the problem, the project’s aims, the impact that the project may have on the nursing practice, and the coverage of this condition are the primary focuses of this paper.
• Depression and Anxiety in Dialysis Patients However, the study indicates the lack of research behind the connection of depression and cognitive impairment, which is a significant limitation to the conclusive statement.
• Adolescent Grief and Depression In looking for an activity that may help him or her keep away from the pain he or she is experiencing, the victim may decide to engage in sexual activities. Later, the adolescent is also […]
• Suicide and Depression in Students Students who belong to racial and ethnic minorities constitute the group of risk connected with high depression and suicidal rates and it is the primary task of health teachers to reduce suicidal rates among all […]
• Depression Disorder: Key Factors Epidemiology refers to the study of the distribution and determinants of health related events in specific populations and its applications to health problems.
• Depression Effects of School Children However the present difficulties that he is going through being a 16 year old; may be associated to a possible cause of Down syndrome complications, or the feelings and behavioral deficiency he associates to the […]
• Depression, Hallucination, and Suicide: Mental Cases How they handle the process determines the kind of aftermath they will experience for instance it can take the route of hallucinations which is treatable or suicide which is irreversible thus how each case is […]
• Depression, Its Perspective and Management Therefore this paper seeks to point out that stress is a major ingredient of depression; show the causes, symptoms, highlight how stresses is manifested in different kinds of people, show how to manage stress that […]
• Daily Living, Depression, and Social Support Activities of Elderly Turkish People Navigating the delicate and often convoluted maze of the current issues affecting the elderly has continued to present challenges to the professionals in the field especially with the realization that these issues and needs are […]
• The Theory of Personality Psychology During Depression The study concerns personality pathology, and the results of the treatment given to patients who are under depression, and how personalities may have adverse effects on the consequences of the cure.
• Depression and the Media Other components of the cognitive triad of depression are the aspect of seeing the environment as overwhelming and that one is too small to make an impact and also seeing the future as bleak and […]
• Poor Body Image, Anxiety, and Depression: Women Who Undergo Breast Implants H02: There is no difference in overt attractiveness to, and frequency of intimacy initiated by, the husband or cohabitating partner of a breast implant patient both before and after the procedure.
• Reducing Anxiety and Depression With Exercise Regardless of the type of results achieved, it is recommendable for people undergoing mental problems like depression and anxiety to exercise regularly.
• Stress, Depression and Psychoneuroimmunology The causes and symptoms of stress may vary from person to person and the symptoms can be mental as well as physical.
• A Critical Evaluation of Major Depression This paper has actively shown how factors such as financial insecurity, job loss, income, and educational inequalities, lifestyle diseases, and breakdown of the social fabric have acted to propel the mental disorder by making use […]
• Depression, Substance Abuse and Suicide in Elderly While significant body of research has been devoted to the study of depression in elderly, little attention has been paid to the investigation of substance abuse, emotional instability, burden feelings, and depression.
• Adult Depression Sufferer’s and Withdrawal From Family and Friends
• Depression: Helping Students in the Classroom
• Major Depression: Treating Depression in the Context of Marital Discord
• Family Therapy for Treating Major Depression
• Adverse Childhood Experiences Cause Depression
• Depression and Alzheimer’s Disease
• Rumination, Perfectionism and Depression in Young People
• “Gender Differences in Depression” by Nolen-Hoeksema
• Anxiety and Depression Disorders
• Beck’s Cognitive Therapy Approach to Depression Treatment
• Cannabis Abuse Increases the Risk of Depression
• Depression: Risk Factors, Incidence, Preventive Measures & Prognostic Factors
• Depression Diagnostics Methods
• Concept Analysis of Loneliness, Depression, Self-esteem
• Teen Suicide and Depression
• Depression and Diabetes Association in Adults
• The Correlation Between Perfectionism and Depression
• Geriatric Dementia, Delirium, and Depression
• Dementia, Delirium, and Depression in Older Adults
• Dealing with Depression in the Workplace
• Depression in People With Alcohol Dependence
• Depression and Anxiety Due to School and Work-Related Stress
• Creating a Comprehensive Psychological Treatment Plan: Depression
• Experimental Psychology. Bouldering for Treating Depression
• Depression and Psychotherapy in Adolescence
• Postpartum Depression: Treatment and Therapy
• Atypical Depression Symptoms and Treatment
• Dementia, Delirium, and Depression in Frail Elders
• Depression & Patient Safety: Speak Up Program
• Mindfulness Meditation Therapy in Depression Cases
• A Review of Postpartum Depression and Continued Post Birth Support
• Psychodynamic Therapy for Depression
• Depression Screening in Primary Care for Adolescents
• Freud’s Depression: Cognitive-Behavioral Interventions
• Optimal Mental Health Approaches: Depression & Anxiety
• Great Depression in “A Worn Path” by Eudora Welty
• Depression in Adolescents and Interventions
• Bipolar Disorder: Reoccurring Hypomania & Depression
• Postpartum Depression: Understanding the Needs of Women
• Major Depression Treatment During Pregnancy
• Patients’ Depression and Practitioners’ Suggestions
• Traditional Symptoms of Depression
• Social Media Impact on Depression and Eating Disorder
• Anxiety and Depression in Children and Adolescents
• Depression Studies and Online Research Sources
• Drug Abuse and Depression Treatment
• Depression Explanation in Psychological Theories
• Food Insecurity and Depression in Poor Families
• Peer Popularity and Depression Among Adolescents
• Alcohol Abuse, Depression and Human Trafficking
• Depression Assessment Using Intake Notes
• Depression in Adolescents and Cognitive Therapy
• Diagnosing Depression: Implementation and Evaluation Plan
• Beck Depression Inventory: Evaluation Plan
• Depression in Iranian Women and Health Policies
• Depression Patients and Psychiatrist’s Work
• Depression Patients’ Needs and Treatment Issues
• Suicide and Depression: Connection, Signs and Age
• Health Promotion: Depression Awareness in Teenagers
• Depression and Cancer in Caucasian Female Patient
• Depression in Patients with Comorbidity
• Depression After Transcranial Magnetic Stimulation Treatment
• Depression and Psychosis: 32-Year-Old Female Patient
• Postpartum Depression and Acute Depressive Symptoms
• Women with Heart Disease: Risk of Depression
• Postpartum Depression and Its Peculiarities
• Exercises as a Treatment for Depression
• Depression Treatment Changes in 2006-2017
• Depression in Elders: Social Factors
• Depression Among High School Students
• False Memories in Patients with Depression
• Postpartum Depression Analysis in “Yellow Wallpaper”
• The Canadian Depression Causes
• Widowhood Effects on Men’s and Women’s Depression
• Teen Website: Fish Will Keep Depression Away
• Bipolar Expeditions: Mania and Depression
• Obesity and Major Depression Association
• Fast Food, Obesity, Depression, and Other Issues
• Depression in the Future Public Health
• Depression: Patients With a Difficult Psychological State
• Depression: Pathophysiology and Treatment
• Stress, Depression, and Responses to Them
• Beck Depression Inventory in Psychological Practice
• Problem of the Depression in Teenagers
• Supporting the Health Needs of Patients With Parkinson’s, Preeclampsia, and Postpartum Depression
• Hamilton Depression Rating Scale Application
• Psychological Measures: The Beck Depression Inventory
• Yoga for Depression and Anxiety
• Sleep Disturbance, Depression, Anxiety Correlation
• Depression in Late Life: Interpersonal Psychotherapy
• Postpartum Depression and Comorbid Disorders
• Arab-Americans’ Acculturation and Depression
• Organizational Behaviour: Depression in the Workplace
• Relationship Between Depression and Sleep Disturbance
• Child’s Mental Health and Depression in Adulthood
• Parents’ Depression and Toddler Behaviors
• Managing Stress and Depression at Work Places – Psychology
• Job’ Stress and Depression
• Depression Measurements – Psychology
• Methodological Bias Associated with Sex Depression
• Relationship Between Sleep and Depression in Adolescence
• The Effects of Depression on Physical Activity
• Psychological Disorder: Depression
• Depression and Workplace Violence
• The Effects of Forgiveness Therapy on Depression, Anxiety and Posttraumatic Stress for Women After Spousal Emotional Abuse
• Depression Diagnosis and Theoretical Models
• The Impact of Exercise on Women Who Suffer From Depression
• Evolutionary Psychology: Depression
• Effect of Social Media on Depression
• Depression in the Elderly
• Poly-Substance Abuse in Adolescent Males With Depression
• How Does Peer Pressure Contribute to Adolescent Depression?
• How Do Genetic and Environmental Factors Contribute To The Expression of Depression?
• Depression and Cognitive Therapy
• Cognitive Treatment of Depression
• Book Review: “Breadwinning Daughters: Young Women Working in a Depression- Era City, 1929-1939” by Katrina Srigley
• Depression: A Critical Evaluation
• Psychopharmacological Treatment for Depression
• “Breadwinning Daughters: Young Working Women in a Depression-Era City” by Katrina Srigley
• Depression in female adolescents
• Interpersonal Communication Strategies Regarding Depression
• Depression: Law Enforcement Officers and Stress
• Social Influences on Behavior: Towards Understanding Depression and Alcoholism Based on Social Situations
• Depression Experiences in Law Enforcement
• Childhood Depression & Bi-Polar Disorder
• Depression Psychological Evaluation
• Concept of Childhood Depression
• Correlation Between Multiple Pregnancies and Postpartum Depression or Psychosis
• Depression and Its Effects on Participants’ Performance in the Workplace
• Catatonic Depression: Etiology and Management
• The Children’s Depression Inventory (CDI) Measure
• Depression: A Cross-Cultural Perspective
• Depression Levels and Development
• Depression Treatment: Rational Emotive Behavior Therapy
• Concept of Depression Disorder
• Does Divorce Have a Greater Impact on Men than on Women in Terms of Depression?
• Oral versus Written Administration of the Geriatric Depression Scale

❓Research Questions for a Depression Essay

• Does Poverty Impact Depression in African American Adolescents and the Development of Suicidal Ideations?
• Does Neighborhood Violence Lead to Depression Among Caregivers of Children With Asthma?
• Does Parent Depression Correspond With Child Depression?
• How Depression Affects Our Lives?
• Does Brain-Derived Neurotrophic Factor Have an Effect on Depression Levels in Elderly Women?
• How Can Overcome Depression Through 6 Lifestyle Changes?
• Does Maternal Depression Have a Negative Effect on Parent-Child Attachment?
• Can Providers’ Education About Postpartum Depression?
• Can Vacation Help With Depression?
• How Children Deal With Depression?
• Can Diet Help Stop Depression and Violence?
• Does Depression Assist Eating Disorders?
• Does Depression Lead to Suicide and Decreased Life Expectancy?
• Can Obesity Cause Depression?
• Can Exercise Increase Fitness and Reduce Weight in Patients With Depression?
• Does Fruit and Vegetable Consumption During Adolescence Predict Adult Depression?
• Does Depression Cause Cancer?
• Does Money Relieve Depression?
• Does the Average Person Experience Depression Throughout Their Life?
• Are Vaccines Cause Depression?
• Does Social Anxiety Lead to Depression?
• Does Stress Cause Depression?
• How Bipolar and Depression Are Linked?
• Does Postpartum Depression Affect Employment?
• Does Postpartum Depression Predict Emotional and Cognitive Difficulties in 11-Year-Olds?
• Does Regular Exercise Reduce Stress Levels, and Thus Reduce Symptoms of Depression?
• Does the Natural Light During Winters Really Create Depression?
• How Can Art Overcome Depression?
• How Anxiety and Depression Are Connected?
• Does Positive Psychology Ease Symptoms of Depression?
• Chicago (A-D)
• Chicago (N-B)

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How to Discuss Your Mental Health on College Applications

Should you write about depression in your personal statement? Should you disclose mental health challenges elsewhere on your college application? Here’s what experts say.

Within the next few months, many rising high school seniors will be staring at a blank computer screen with the same question on their minds: What should I write about in my college application essay?  This question can feel heavy.  After all, by the time students approach the end of their junior year, they’ve surely heard lots about “THE” college essay.  The concept can feel overwhelming so it’s no surprise that many students struggle when it comes to choosing the perfect topic.

For students who experienced a mental health challenge while in high school, this question takes on another dimension. Should they talk about how they coped with say, depression, or any other mental health condition? Should they refer to it only in passing? Should they avoid mentioning it at all?  What is the best way to handle such an important topic?

While this is a very complicated topic, the college planning experts I talked with all offered similar advice.

The Purpose of a College Application Essay

Before thinking about whether or not you should write about mental health in your college essay, you should remember what the essay — or the “personal statement”— is all about in the first place.  What is the purpose of the essay?

No matter which prompt students select, and for all college applicants, those with or without mental health challenges, the essay is the only part of the application in which college admissions officers have the opportunity to hear the voices of the student. The rest of the application contains numbers, statistics, and comments from teachers and counselors.

This is why the personal statement, as college planning experts concur, is where you should share part of your true self in the most positive light. Think about what a college wants to know about you as a person, or what a university would gain by having you become a part of the campus community.  Dig deep to figure out what makes you, you.

Use your essay as an opportunity to bring your college application to life. Try to strive for it to represent you in an authentic yet optimistic way. One former reader of applications at a top university’s admission office shared a fun way to see if your essay checks out.  She asked me, “Does the essay pass the midnight test”?

Picture an exhausted admissions officer with a stack of unread application files on her desk. She is reading yours at midnight at the end of a 16-hour day. Does your essay draw the officer in and make her eager to read until the end of your essay to learn more about you? Will she be eager enough for her to conclude that, yes, we want this student on our campus next fall? Or does your essay sound far too similar to some of the others she’s read that day?

The purpose of your essay is to take the reader beyond the numbers (test scores and GPA) and into who you are as a real live human being.

Experts on Writing About Mental Health

All counselors interviewed for this piece agreed that students’ college essays should not be about their struggles with mental health. Wendy Kahn , a Chicago-based college planner, and Anna Seltz, of Higher Ed U , a college consulting organization in Philadelphia, both spoke about how students should try to talk about themselves in a positive light, taking the opportunity to showcase one of their many outstanding qualities, like intellectual curiosity, personal growth, or maturity.

A couple of the counselors — Bruce Vinik of Vinik Educational Services and Marsha Shaines of College Strategies in Kensington, Maryland — said that the only case in which a student should consider writing about her mental health challenges is if the struggle truly defines her as a person. Even then, both counselors saw this as the rare exception, and suggest that instead, most students should take advantage of the opportunity to explore one of the many other attributes that makes them unique. Vinik says that mental health problems should only be shared in the essay if the college would not be able to understand the applicant without knowing about this part of her. Generally, he discourages selecting this as a primary topic.

The Additional Information Section

All of the college planners mentioned above agree that if your mental health struggle in high school clearly impacted your performance, then you should mention it in the “Additional Information” portion of the Common Application — but only in a factual manner. If you missed three months of your sophomore year to deal with a mental health condition, you should explain that you spent those months dealing with a “health challenge,” overcame it, and are now back on track, advises Vinik.

The three other college counselors generally agreed with this sentiment. All expressed that if the mental health challenges have made an impact on your grades, involvement in class, attendance, or ability to participate in school activities, you should provide a short, factual summary (no more than two paragraphs) for background purposes, always emphasizing your recovery after these difficult moments and your preparedness for a college environment.

Seltz suggests that talking about this in your admissions interview may be another route that applicants can explore. Seltz recommends taking an approach like the one outlined for personal statements above: Briefly explain how the challenge affected your grades and focus mostly on the fact that those problems are now under control.  Making sure to emphasize the way/s that the challenge helped you to grow as a person is also important.

All of the college planners suggest that you talk with your high school counselor to ensure that what you are saying about mental illness in the college application is consistent with what the counselor may or may not say in her own counselor recommendation. Or, if you’d prefer that the counselor not address your mental health issues, request that as well. School counselors are almost always open to any guidance you may have for what you’d like them to include in or leave out of your letter of recommendation.

Dealing With Mental Health Challenges Past the Application

Being told that you cannot share a part of yourself that may have had a large impact on your life can be difficult to hear. Unfortunately, mental health is a stigmatized topic, and it’s difficult to explore its nuances and complexities in the short and streamlined format of a college application.  It is also extremely important to remember that with or without mental health challenges, you are far more complex than a 650-word personal statement.

The fact that you are not writing about it on your application doesn’t mean that colleges don’t want the “real” you, or that you will be unable to succeed. A mental health condition does not disqualify you from having an excellent collegiate experience by any means, the same way that a physical limitation would not interfere with your success as a student. As you explore your college options, be sure to look for campuses that are particularly mental-health friendly, and focus on finding resources you can rely on as a student. From counseling services to wellness organizations, many campuses make student mental health a priority, and selecting this kind of college will help you embrace your challenges and thrive in a new environment.

If you are worried that your problems are not yet under control — and that college may exacerbate them — you may want to consider taking a gap year and working with a local counselor to prepare for the big transition.  There are lots of really wonderful gap year programs for students in this exact position. If you think you might be interested in this option, talk with your school counselor about exploring what programs are available to you.

Be personal in your college application essay — but do so in an optimistic and positive way. The purpose of the essay is to convince the reader that you belong on their campus next fall. Don’t leave the reader with any unanswered questions or red flags about you.  Be clear about who you are and your will to enhance whatever campus you find yourself on.  This is the best way to tell the story of who you are.

If there are circumstances that need to be explained — such as time off, a drop in grades, or diminished participation in extracurricular activities, do so in a factual and concise manner in the “Additional Information” section.

Yes, you may have experienced a mental health challenge, and/or you may be going to college with mental illness. But don’t let that singularly define you as a person. You have the propensity to offer much more to a college than your diagnosis. And the personal statement essay is the place to show the college who you are as an individual, why you are ready for college, and what strong and special qualities you will bring to the campus community if accepted.

If you’re currently applying for colleges and are planning on taking the SAT or the ACT, our tutors are here to help. Connect with them for your respective test below:

Related Highschool & College Admissions Resources:

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434 Depression Essay Titles & Research Topics: Argumentative, Controversial, and More

Depression is undeniably one of the most prevalent mental health conditions globally, affecting approximately 5% of adults worldwide. It often manifests as intense feelings of hopelessness, sadness, and a loss of interest in previously enjoyable activities. Many also experience physical symptoms like fatigue, sleep disturbances, and appetite changes. Recognizing and addressing this mental disorder is extremely important to save lives and treat the condition.

In this article, we’ll discuss how to write an essay about depression and introduce depression essay topics and research titles for students that may be inspirational.

• 🔝 Top Depression Essay Titles
• ✅ Essay Prompts
• 💡 Research Topics
• 🔎 Essay Titles
• 💭 Speech Topics
• 📝 Essay Structure

🔗 References

🔝 top 12 research titles about depression.

• How is depression treated?
• Depression: Risk factors.
• The symptoms of depression.
• What types of depression exist?
• Depression in young people.
• Differences between anxiety and depression.
• The parents’ role in depression therapy.
• Drugs as the root cause of depression.
• Dangerous consequences of untreated depression.
• Effect of long-term depression.
• Different stages of depression.
• Treatment for depression.

✅ Prompts for Essay about Depression

Struggling to find inspiration for your essay? Look no further! We’ve put together some valuable essay prompts on depression just for you!

Prompt for Personal Essay about Depression

Sharing your own experience with depression in a paper can be a good idea. Others may feel more motivated to overcome their situation after reading your story. You can also share valuable advice by discussing things or methods that have personally helped you deal with the condition.

For example, in your essay about depression, you can:

• Tell about the time you felt anxious, hopeless, or depressed;
• Express your opinion on depression based on the experiences from your life;
• Suggest a way of dealing with the initial symptoms of depression ;
• Share your ideas on how to protect mental health at a young age.

How to Overcome Depression: Essay Prompt

Sadness is a common human emotion, but depression encompasses more than just sadness. As reported by the National Institute of Mental Health, around 21 million adults in the United States, roughly 8.4% of the total adult population , faced at least one significant episode of depression in 2020. When crafting your essay about overcoming depression, consider exploring the following aspects:

• Depression in young people and adolescents;
• The main causes of depression;
• The symptoms of depression;
• Ways to treat depression;
• Help from a psychologist (cognitive behavioral therapy or interpersonal therapy ).

Postpartum Depression: Essay Prompt

The birth of a child often evokes a spectrum of powerful emotions, spanning from exhilaration and happiness to apprehension and unease. It can also trigger the onset of depression. Following childbirth, many new mothers experience postpartum “baby blues,” marked by shifts in mood, bouts of tears, anxiety, and sleep disturbances. To shed light on the subject of postpartum depression, explore the following questions:

• What factors may increase the risk of postpartum depression?
• Is postpartum depression predictable?
• How to prevent postpartum depression?
• What are the symptoms of postpartum depression?
• What kinds of postpartum depression treatments exist?

Prompt for Essay about Teenage Depression

Teenage depression is a mental health condition characterized by sadness and diminishing interest in daily activities. It can significantly impact a teenager’s thoughts, emotions, and behavior, often requiring long-term treatment and support.

By discussing the primary symptoms of teenage depression in your paper, you can raise awareness of the issue and encourage those in need to seek assistance. You can pay attention to the following aspects:

• Emotional changes (feelings of sadness, anger, hopelessness, guilt, etc.);
• Behavioral changes (loss of energy and appetite , less attention to personal hygiene, self-harm, etc.);
• New addictions (drugs, alcohol, computer games, etc.).

💡 Research Topics about Depression

• The role of genetics in depression development.
• The effectiveness of different psychotherapeutic interventions for depression.
• Anti-depression non-pharmacological and medication treatment .
• The impact of childhood trauma on the onset of depression later in life.
• Exploring the efficacy of antidepressant medication in different populations.
• The impact of exercise on depression symptoms and treatment outcomes.
• Mild depression: pharmacotherapy and psychotherapy .
• The relationship between sleep disturbances and depression.
• The role of gut microbiota in depression and potential implications for treatment.
• Investigating the impact of social media on depression rates in adolescents.
• Depression, dementia, and delirium in older people .
• The efficacy of cognitive-behavioral therapy in preventing depression relapse.
• The influence of hormonal changes on depression risk.
• Assessing the effectiveness of self-help and digital interventions for depression.
• Herbal and complementary therapies for depression .
• The relationship between personality traits and vulnerability to depression.
• Investigating the long-term consequences of untreated depression on physical health.
• Exploring the link between chronic pain and depression.
• Depression in the elderly male .
• The impact of childhood experiences on depression outcomes in adulthood.
• The use of ketamine and other novel treatments for depression.
• The effect of stigma on depression diagnosis and treatment.
• The conducted family assessment: cases of depression .
• The role of social support in depression recovery.
• The effectiveness of online support groups for individuals with depression.
• Depression and cognitive decline in adults.
• Depression: PICOT question component exploration .
• Exploring the impact of nutrition and dietary patterns on depression symptoms.
• Investigating the efficacy of art-based therapies in depression treatment.
• The role of neuroplasticity in the development and treatment of depression.
• Depression among HIV-positive women .
• The influence of gender on depression prevalence and symptomatology.
• Investigating the impact of workplace factors on depression rates and outcomes.
• The efficacy of family-based interventions in reducing depression symptoms in teenagers.
• Frontline nurses’ burnout, anxiety, depression, and fear statuses .
• The role of early-life stress and adversity in depression vulnerability.
• The impact of various environmental factors on depression rates.
• Exploring the link between depression and cardiovascular health .
• Depression detection in adults in nursing practice .
• Virtual reality as a therapeutic tool for depression treatment.
• Investigating the impact of childhood bullying on depression outcomes.
• The benefits of animal-assisted interventions in depression management.
• Depression and physical exercise .
• The relationship between depression and suicidal behavior .
• The influence of cultural factors on depression symptom expression.
• Investigating the role of epigenetics in depression susceptibility.
• Depression associated with cognitive dysfunction .
• Exploring the impact of adverse trauma on the course of depression.
• The efficacy of acceptance and commitment therapy in treating depression.
• The relationship between depression and substance use disorders .
• Depression and anxiety among college students .
• Investigating the effectiveness of group therapy for depression.
• Depression and chronic medical conditions .

Psychology Research Topics on Depression

• The influence of early attachment experiences on the development of depression.
• The impact of negative cognitive biases on depression symptomatology.
• Depression treatment plan for a queer patient .
• Examining the relationship between perfectionism and depression.
• The role of self-esteem in depression vulnerability and recovery.
• Exploring the link between maladaptive thinking styles (e.g., rumination, catastrophizing) and depression.
• Investigating the impact of social support on depression outcomes and resilience.
• Identifying depression in young adults at an early stage .
• The influence of parenting styles on the risk of depression in children and adolescents.
• The role of self-criticism and self-compassion in depression treatment.
• Exploring the relationship between identity development and depression in emerging adulthood.
• The role of learned helplessness in understanding depression and its treatment.
• Depression in the elderly .
• Examining the connection between self-efficacy beliefs and depression symptoms.
• The influence of social comparison processes on depression and body image dissatisfaction .
• Exploring the impact of trauma-related disorders on depression.
• The role of resilience factors in buffering against the development of depression.
• Investigating the relationship between personality traits and depression.
• Depression and workplace violence .
• The impact of cultural factors on depression prevalence and symptom presentation.
• Investigating the effects of chronic stress on depression risk.
• The role of coping strategies in depression management and recovery.
• The correlation between discrimination/prejudice and depression/anxiety .
• Exploring the influence of gender norms and societal expectations on depression rates.
• The impact of adverse workplace conditions on employee depression.
• Investigating the effectiveness of narrative therapy in treating depression.
• Cognitive behavior and depression in adolescents .
• Childhood emotional neglect and adult depression.
• The influence of perceived social support on treatment outcomes in depression.
• The effects of childhood bullying on the development of depression.
• The impact of intergenerational transmission of depression within families.
• Depression in children: symptoms and treatments .
• Investigating the link between body dissatisfaction and depression in adolescence.
• The influence of adverse life events and chronic stressors on depression risk.
• The effects of peer victimization on the development of depression in adolescence.
• Counselling clients with depression and addiction .
• The role of experiential avoidance in depression and its treatment.
• The impact of social media use and online interactions on depression rates.
• Depression management in adolescent .
• Exploring the relationship between emotional intelligence and depression symptomatology.
• Investigating the influence of cultural values and norms on depression stigma and help-seeking behavior.
• The effects of childhood maltreatment on neurobiological markers of depression.
• Psychological and emotional conditions of suicide and depression .
• Exploring the relationship between body dissatisfaction and depression.
• The influence of self-worth contingencies on depression vulnerability and treatment response.
• The impact of social isolation and loneliness on depression rates.
• Psychology of depression among college students .
• The effects of perfectionistic self-presentation on depression in college students.
• The role of mindfulness skills in depression prevention and relapse prevention.
• Investigating the influence of adverse neighborhood conditions on depression risk.
• Personality psychology and depression .
• The impact of attachment insecurity on depression symptomatology.

Postpartum Depression Research Topics

• Identifying risk factors for postpartum depression.
• Exploring the role of hormonal changes in postpartum depression.
• “Baby blues” or postpartum depression and evidence-based care .
• The impact of social support on postpartum depression.
• The effectiveness of screening tools for early detection of postpartum depression.
• The relationship between postpartum depression and maternal-infant bonding .
• Postpartum depression educational program results .
• Identifying effective interventions for preventing and treating postpartum depression.
• Examining the impact of cultural factors on postpartum depression rates.
• Investigating the role of sleep disturbances in postpartum depression.
• Depression and postpartum depression relationship .
• Exploring the impact of a traumatic birth experience on postpartum depression.
• Assessing the impact of breastfeeding difficulties on postpartum depression.
• Understanding the role of genetic factors in postpartum depression.
• Postpartum depression: consequences .
• Investigating the impact of previous psychiatric history on postpartum depression risk.
• The potential benefits of exercise on postpartum depression symptoms.
• The efficacy of psychotherapeutic interventions for postpartum depression.
• Postpartum depression in the twenty-first century .
• The influence of partner support on postpartum depression outcomes.
• Examining the relationship between postpartum depression and maternal self-esteem.
• The impact of postpartum depression on infant development and well-being.
• Maternal mood symptoms in pregnancy and postpartum depression .
• The effectiveness of group therapy for postpartum depression management.
• Identifying the role of inflammation and immune dysregulation in postpartum depression.
• Investigating the impact of childcare stress on postpartum depression.
• Postpartum depression among low-income US mothers .
• The role of postnatal anxiety symptoms in postpartum depression.
• The impact of postpartum depression on the marital relationship.
• The influence of postpartum depression on parenting practices and parental stress.
• Postpartum depression: symptoms, role of cultural factors, and ways to support .
• Investigating the efficacy of pharmacological treatments for postpartum depression.
• The impact of postpartum depression on breastfeeding initiation and continuation.
• The relationship between postpartum depression and post-traumatic stress disorder .
• Postpartum depression and its identification .
• The impact of postpartum depression on cognitive functioning and decision-making.
• Investigating the influence of cultural norms and expectations on postpartum depression rates.
• The impact of maternal guilt and shame on postpartum depression symptoms.
• Beck’s postpartum depression theory: purpose, concepts, and significance .
• Understanding the role of attachment styles in postpartum depression vulnerability.
• Investigating the effectiveness of online support groups for women with postpartum depression.
• The impact of socioeconomic factors on postpartum depression prevalence.
• Perinatal depression: research study and design .
• The efficacy of mindfulness-based interventions for postpartum depression.
• Investigating the influence of birth spacing on postpartum depression risk.
• The role of trauma history in postpartum depression development.
• The link between the birth experience and postnatal depression .
• How does postpartum depression affect the mother-infant interaction and bonding ?
• The effectiveness of home visiting programs in preventing and managing postpartum depression.
• Assessing the influence of work-related stress on postpartum depression.
• The relationship between postpartum depression and pregnancy-related complications.
• The role of personality traits in postpartum depression vulnerability.

🔎 Depression Essay Titles

Depression essay topics: cause & effect.

• The effects of childhood trauma on the development of depression in adults.
• The impact of social media usage on the prevalence of depression in adolescents.
• “Predictors of Postpartum Depression” by Katon et al.
• The effects of environmental factors on depression rates.
• The relationship between academic pressure and depression among college students.
• The relationship between financial stress and depression.
• The best solution to predict depression because of bullying .
• How does long-term unemployment affect mental health ?
• The effects of unemployment on mental health, particularly the risk of depression.
• The impact of genetics and family history of depression on an individual’s likelihood of developing depression.
• The relationship between depression and substance abuse .
• Child abuse and depression .
• The role of gender in the manifestation and treatment of depression.
• The effects of chronic stress on the development of depression.
• The link between substance abuse and depression.
• Depression among students at Elon University .
• The influence of early attachment styles on an individual’s vulnerability to depression.
• The effects of sleep disturbances on the severity of depression.
• Chronic illness and the risk of developing depression.
• Depression: symptoms and treatment .
• Adverse childhood experiences and the likelihood of experiencing depression in adulthood.
• The relationship between chronic illness and depression.
• The role of negative thinking patterns in the development of depression.
• Effects of depression among adolescents .
• The effects of poor body image and low self-esteem on the prevalence of depression.
• The influence of social support systems on preventing symptoms of depression.
• The effects of child neglect on adult depression rates.
• Depression caused by hormonal imbalance .
• The link between perfectionism and the risk of developing depression.
• The effects of a lack of sleep on depression symptoms.
• The effects of childhood abuse and neglect on the risk of depression.
• Social aspects of depression and anxiety .
• The impact of bullying on the likelihood of experiencing depression.
• The role of serotonin and neurotransmitter imbalances in the development of depression.
• The impact of a poor diet on depression rates.
• Depression and anxiety run in the family .
• The effects of childhood poverty and socioeconomic status on depression rates in adults.
• The impact of divorce on depression rates.
• The relationship between traumatic life events and the risk of developing depression.
• The influence of personality traits on susceptibility to depression.
• The impact of workplace stress on depression rates.
• Depression in older adults: causes and treatment .
• The impact of parental depression on children’s mental health outcomes.
• The effects of social isolation on the prevalence and severity of depression.
• The role of cultural factors in the manifestation and treatment of depression.
• The relationship between childhood bullying victimization and future depressive symptoms.
• The impact of early intervention and prevention programs on reducing the risk of postpartum depression.
• Treating mood disorders and depression .
• How do hormonal changes during pregnancy contribute to the development of depression?
• The effects of sleep deprivation on the onset and severity of postpartum depression.
• The impact of social media on depression rates among teenagers.
• The role of genetics in the development of depression.
• The impact of bullying on adolescent depression rates.
• Mental illness, depression, and wellness issues .
• The effects of a sedentary lifestyle on depression symptoms.
• The correlation between academic pressure and depression in students.
• The relationship between perfectionism and depression.
• The correlation between trauma and depression in military veterans.
• Anxiety and depression during childhood and adolescence .
• The impact of racial discrimination on depression rates among minorities.
• The relationship between chronic pain and depression.
• The impact of social comparison on depression rates among young adults.
• The effects of childhood abuse on adult depression rates.

Depression Argumentative Essay Topics

• The role of social media in contributing to depression among teenagers.
• The effectiveness of antidepressant medication: an ongoing debate.
• Depression treatment: therapy or medications ?
• Should depression screening be mandatory in schools and colleges?
• Is there a genetic predisposition to depression?
• The stigma surrounding depression: addressing misconceptions and promoting understanding.
• Implementation of depression screening in primary care .
• Is psychotherapy more effective than medication in treating depression?
• Is teenage depression overdiagnosed or underdiagnosed: a critical analysis.
• The connection between depression and substance abuse: untangling the relationship.
• Humanistic therapy of depression .
• Should ECT (electroconvulsive therapy) be a treatment option for severe depression?
• Where is depression more prevalent: in urban or rural communities? Analyzing the disparities.
• Is depression a result of chemical imbalance in the brain? Debunking the myth.
• Depression: a serious mental and behavioral problem .
• Should depression medication be prescribed for children and adolescents?
• The effectiveness of mindfulness-based interventions in managing depression.
• Should depression in the elderly be considered a normal part of aging?
• Is depression hereditary? Investigating the role of genetics in depression risk.
• Different types of training in managing the symptoms of depression .
• The effectiveness of online therapy platforms in treating depression.
• Should psychedelic therapy be explored as an alternative treatment for depression?
• The connection between depression and cardiovascular health: Is there a link?
• The effectiveness of cognitive-behavioral therapy in preventing depression relapse.
• Depression as a bad a clinical condition .
• Should mind-body interventions (e.g., yoga , meditation) be integrated into depression treatment?
• Should emotional support animals be prescribed for individuals with depression?
• The effectiveness of peer support groups in decreasing depression symptoms.
• The use of antidepressants: are they overprescribed or necessary for treating depression?
• Adult depression and anxiety as a complex problem .
• The effectiveness of therapy versus medication in treating depression.
• The stigma surrounding depression and mental illness: how can we reduce it?
• The debate over the legalization of psychedelic drugs for treating depression.
• The relationship between creativity and depression: does one cause the other?
• Cognitive-behavioral therapy for generalized anxiety disorder and depression .
• The role of childhood trauma in shaping adult depression: Is it always a causal factor?
• The debate over the medicalization of sadness and grief as forms of depression.
• Alternative therapies, such as acupuncture or meditation, are effective in treating depression.
• Depression as a widespread mental condition .

Controversial Topics about Depression

• The existence of “chemical imbalance” in depression: fact or fiction?
• The over-reliance on medication in treating depression: are alternatives neglected?
• Is depression overdiagnosed and overmedicated in Western society?
• Measurement of an individual’s level of depression .
• The role of Big Pharma in shaping the narrative and treatment of depression.
• Should antidepressant advertisements be banned?
• The inadequacy of current diagnostic criteria for depression: rethinking the DSM-5.
• Is depression a biological illness or a product of societal factors?
• Literature review on depression .
• The overemphasis on biological factors in depression treatment: ignoring environmental factors.
• Is depression a normal reaction to an abnormal society?
• The influence of cultural norms on the perception and treatment of depression.
• Should children and adolescents be routinely prescribed antidepressants?
• The role of family in depression treatment .
• The connection between depression and creative genius: does depression enhance artistic abilities?
• The ethics of using placebo treatment for depression studies.
• The impact of social and economic inequalities on depression rates.
• Is depression primarily a mental health issue or a social justice issue?
• Depression disassembling and treating .
• Should depression screening be mandatory in the workplace?
• The influence of gender bias in the diagnosis and treatment of depression.
• The controversial role of religion and spirituality in managing depression.
• Is depression a result of individual weakness or societal factors?
• Abnormal psychology: anxiety and depression case .
• The link between depression and obesity: examining the bidirectional relationship.
• The connection between depression and academic performance : causation or correlation?
• Should depression medication be available over the counter?
• The impact of internet and social media use on depression rates: harmful or beneficial?
• Interacting in the workplace: depression .
• Is depression a modern epidemic or simply better diagnosed and identified?
• The ethical considerations of using animals in depression research.
• The effectiveness of psychedelic therapies for treatment-resistant depression.
• Is depression a disability? The debate on workplace accommodations.
• Polysubstance abuse among adolescent males with depression .
• The link between depression and intimate partner violence : exploring the relationship.
• The controversy surrounding “happy” pills and the pursuit of happiness.
• Is depression a choice? Examining the role of personal responsibility.

Good Titles for Depression Essays

• The poetic depictions of depression: exploring its representation in literature.
• The melancholic symphony: the influence of depression on classical music.
• Moderate depression symptoms and treatment .
• Depression in modern music: analyzing its themes and expressions.
• Cultural perspectives on depression: a comparative analysis of attitudes in different countries.
• Contrasting cultural views on depression in Eastern and Western societies.
• Diagnosing depression in the older population .
• The influence of social media on attitudes and perceptions of depression in global contexts.
• Countries with progressive approaches to mental health awareness.
• From taboo to acceptance: the evolution of attitudes towards depression.
• Depression screening tool in acute settings .
• The Bell Jar : analyzing Sylvia Plath’s iconic tale of depression .
• The art of despair: examining Frida Kahlo’s self-portraits as a window into depression.
• The Catcher in the Rye : Holden Caulfield’s battle with adolescent depression.
• Music as therapy: how jazz artists turned depression into art.
• Depression screening tool for a primary care center .
• The Nordic paradox: high depression rates in Scandinavian countries despite high-quality healthcare.
• The Stoic East: how Eastern philosophies approach and manage depression.
• From solitude to solidarity: collective approaches to depression in collectivist cultures.
• The portrayal of depression in popular culture: a critical analysis of movies and TV shows.
• The depression screening training in primary care .
• The impact of social media influencers on depression rates among young adults.
• The role of music in coping with depression: can specific genres or songs help alleviate depressive symptoms?
• The representation of depression in literature: a comparative analysis of classic and contemporary works.
• The use of art as a form of self-expression and therapy for individuals with depression.
• Depression management guidelines implementation .
• The role of religion in coping with depression: Christian and Buddhist practices.
• The representation of depression in the video game Hellblade: Senua’s Sacrifice .
• The role of nature in coping with depression: can spending time outdoors help alleviate depressive symptoms?
• The effectiveness of dance/movement therapy in treating depression among older adults.
• The National Institute for Health: depression management .
• The portrayal of depression in stand-up comedy: a study of comedians like Maria Bamford and Chris Gethard.
• The role of spirituality in coping with depression: Islamic and Hindu practices .
• The portrayal of depression in animated movies : an analysis of Inside Out and The Lion King .
• The representation of depression by fashion designers like Alexander McQueen and Rick Owens.
• Depression screening in primary care .
• The portrayal of depression in documentaries: an analysis of films like The Bridge and Happy Valley .
• The effectiveness of wilderness therapy in treating depression among adolescents.
• The connection between creativity and depression: how art can help heal.
• The role of Buddhist and Taoist practices in coping with depression.
• Mild depression treatment research funding sources .
• The portrayal of depression in podcasts: an analysis of the show The Hilarious World of Depression .
• The effectiveness of drama therapy in treating depression among children and adolescents.
• The representation of depression in the works of Vincent van Gogh and Edvard Munch.
• Depression in young people: articles review .
• The impact of social media on political polarization and its relationship with depression.
• The role of humor in coping with depression: a study of comedians like Ellen DeGeneres.
• The portrayal of depression in webcomics: an analysis of the comics Hyperbole and a Half .
• The effect of social media on mental health stigma and its relationship with depression.
• Depression and the impact of human services workers .
• The masked faces: hiding depression in highly individualistic societies.

💭 Depression Speech Topics

Informative speech topics about depression.

• Different types of depression and their symptoms.
• The causes of depression: biological, psychological, and environmental factors.
• How depression and physical issues are connected .
• The prevalence of depression in different age groups and demographics.
• The link between depression and anxiety disorders .
• Physical health: The effects of untreated depression.
• The role of genetics in predisposing individuals to depression.
• What you need to know about depression .
• How necessary is early intervention in treating depression?
• The effectiveness of medication in treating depression.
• The role of exercise in managing depressive symptoms.
• Depression in later life: overview .
• The relationship between substance abuse and depression.
• The impact of trauma on depression rates and treatment.
• The effectiveness of mindfulness meditation in managing depressive symptoms.
• Enzymes conversion and metabolites in major depression .
• The benefits and drawbacks of electroconvulsive therapy for severe depression.
• The effect of gender and cultural norms on depression rates and treatment.
• The effectiveness of alternative therapies for depression, such as acupuncture and herbal remedies .
• The importance of self-care in managing depression.
• Symptoms of anxiety, depression, and peritraumatic dissociation .
• The role of support systems in managing depression.
• The effectiveness of cognitive-behavioral therapy in treating depression.
• The benefits and drawbacks of online therapy for depression.
• The role of spirituality in managing depression.
• Depression among minority groups .
• The benefits and drawbacks of residential treatment for severe depression.
• What is the relationship between childhood trauma and adult depression?
• How effective is transcranial magnetic stimulation (TMS) for treatment-resistant depression?
• The benefits and drawbacks of art therapy for depression.
• Mood disorder: depression and bipolar .
• The impact of social media on depression rates.
• The effectiveness of dialectical behavior therapy (DBT) in treating depression.
• Depression in older people .
• The impact of seasonal changes on depression rates and treatment options.
• The impact of depression on daily life and relationships, and strategies for coping with the condition.
• The stigma around depression and the importance of seeking help.

Persuasive Speech Topics about Depression

• How important is it to recognize the signs and symptoms of depression ?
• How do you support a loved one who is struggling with depression?
• The importance of mental health education in schools to prevent and manage depression.
• Social media: the rise of depression and anxiety .
• Is there a need to increase funding for mental health research to develop better treatments for depression?
• Addressing depression in minority communities: overcoming barriers and disparities.
• The benefits of including alternative therapies , such as yoga and meditation, in depression treatment plans.
• Challenging media portrayals of depression: promoting accurate representations.
• Two sides of depression disease .
• How social media affects mental health: the need for responsible use to prevent depression.
• The importance of early intervention: addressing depression in schools and colleges.
• The benefits of seeking professional help for depression.
• There is a need for better access to mental health care, including therapy and medication, for those suffering from depression.
• Depression in adolescents and suitable interventions .
• How do you manage depression while in college or university?
• The role of family and friends in supporting loved ones with depression and encouraging them to seek help.
• The benefits of mindfulness and meditation for depression.
• The link between sleep and depression, and how to improve sleep habits.
• How do you manage depression while working a high-stress job?
• Approaches to treating depression .
• How do you manage depression during pregnancy and postpartum?
• The importance of prioritizing employee mental health and providing resources for managing depression in the workplace.
• How should you manage depression while caring for a loved one with a chronic illness?
• How to manage depression while dealing with infertility or pregnancy loss.
• Andrew Solomon: why we can’t talk about depression .
• Destigmatizing depression: promoting mental health awareness and understanding.
• Raising funds for depression research: investing in mental health advances.
• The power of peer support: establishing peer-led programs for depression.
• Accessible mental health services: ensuring treatment for all affected by depression.
• Evidence-based screening for depression in acute care .
• The benefits of journaling for mental health: putting your thoughts on paper to heal.
• The power of positivity: changing your mindset to fight depression .
• The healing power of gratitude in fighting depression.
• The connection between diet and depression: eating well can improve your mood.
• Teen depression and suicide in Soto’s The Afterlife .
• The benefits of therapy for depression: finding professional help to heal.
• The importance of setting realistic expectations when living with depression.

📝 How to Write about Depression: Essay Structure

We’ve prepared some tips and examples to help you structure your essay and communicate your ideas.

Essay about Depression: Introduction

An introduction is the first paragraph of an essay. It plays a crucial role in engaging the reader, offering the context, and presenting the central theme.

A good introduction typically consists of 3 components:

• Hook. The hook captures readers’ attention and encourages them to continue reading.
• Background information. Background information provides context for the essay.
• Thesis statement. A thesis statement expresses the essay’s primary idea or central argument.

Hook : Depression is a widespread mental illness affecting millions worldwide.

Background information : Depression affects your emotions, thoughts, and behavior. If you suffer from depression, engaging in everyday tasks might become arduous, and life may appear devoid of purpose or joy.

Depression Essay Thesis Statement

A good thesis statement serves as an essay’s road map. It expresses the author’s point of view on the issue in 1 or 2 sentences and presents the main argument.

Thesis statement : The stigma surrounding depression and other mental health conditions can discourage people from seeking help, only worsening their symptoms.

Essays on Depression: Body Paragraphs

The main body of the essay is where you present your arguments. An essay paragraph includes the following:

• a topic sentence,
• evidence to back up your claim,
• explanation of why the point is essential to the argument;
• a link to the next paragraph.

Topic sentence : Depression is a complex disorder that requires a personalized treatment approach, comprising both medication and therapy.

Evidence : Medication can be prescribed by a healthcare provider or a psychiatrist to relieve the symptoms. Additionally, practical strategies for managing depression encompass building a support system, setting achievable goals, and practicing self-care.

Depression Essay: Conclusion

The conclusion is the last part of your essay. It helps you leave a favorable impression on the reader.

The perfect conclusion includes 3 elements:

• Rephrased thesis statement.
• Summary of the main points.
• Final opinion on the topic.

Rephrased thesis: In conclusion, overcoming depression is challenging because it involves a complex interplay of biological, psychological, and environmental factors that affect an individual’s mental well-being.

Summary: Untreated depression heightens the risk of engaging in harmful behaviors such as substance abuse and can also result in negative thought patterns, diminished self-esteem, and distorted perceptions of reality.

We hope you’ve found our article helpful and learned some new information. If so, feel free to share it with your friends. You can also try our free online topic generator !

• Pain, anxiety, and depression – Harvard Health | Harvard Health Publishing
• Depression-related increases and decreases in appetite reveal dissociable patterns of aberrant activity in reward and interoceptive neurocircuitry – PMC | National Library of Medicine
• How to Get Treatment for Postpartum Depression – The New York Times
• What Is Background Information and What Purpose Does It Serve? | Indeed.com
• Thesis | Harvard College Writing Center
• Topic Sentences: How Do You Write a Great One? | Grammarly Blog

725 Research Proposal Topics & Title Ideas in Education, Psychology, Business, & More

414 proposal essay topics for projects, research, & proposal arguments.

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Biological, Psychological, and Social Determinants of Depression: A Review of Recent Literature

Olivia remes.

1 Institute for Manufacturing, University of Cambridge, Cambridge CB3 0FS, UK

João Francisco Mendes

2 NOVA Medical School, Universidade NOVA de Lisboa, 1099-085 Lisbon, Portugal; ku.ca.mac@94cfj

Peter Templeton

3 IfM Engage Limited, Institute for Manufacturing, University of Cambridge, Cambridge CB3 0FS, UK; ku.ca.mac@32twp

4 The William Templeton Foundation for Young People’s Mental Health (YPMH), Cambridge CB2 0AH, UK

Associated Data

Depression is one of the leading causes of disability, and, if left unmanaged, it can increase the risk for suicide. The evidence base on the determinants of depression is fragmented, which makes the interpretation of the results across studies difficult. The objective of this study is to conduct a thorough synthesis of the literature assessing the biological, psychological, and social determinants of depression in order to piece together the puzzle of the key factors that are related to this condition. Titles and abstracts published between 2017 and 2020 were identified in PubMed, as well as Medline, Scopus, and PsycInfo. Key words relating to biological, social, and psychological determinants as well as depression were applied to the databases, and the screening and data charting of the documents took place. We included 470 documents in this literature review. The findings showed that there are a plethora of risk and protective factors (relating to biological, psychological, and social determinants) that are related to depression; these determinants are interlinked and influence depression outcomes through a web of causation. In this paper, we describe and present the vast, fragmented, and complex literature related to this topic. This review may be used to guide practice, public health efforts, policy, and research related to mental health and, specifically, depression.

1. Introduction

Depression is one of the most common mental health issues, with an estimated prevalence of 5% among adults [ 1 , 2 ]. Symptoms may include anhedonia, feelings of worthlessness, concentration and sleep difficulties, and suicidal ideation. According to the World Health Organization, depression is a leading cause of disability; research shows that it is a burdensome condition with a negative impact on educational trajectories, work performance, and other areas of life [ 1 , 3 ]. Depression can start early in the lifecourse and, if it remains unmanaged, may increase the risk for substance abuse, chronic conditions, such as cardiovascular disease, and premature mortality [ 4 , 5 , 6 , 7 , 8 ].

Treatment for depression exists, such as pharmacotherapy, cognitive behavioural therapy, and other modalities. A meta-analysis of randomized, placebo-controlled trials of patients shows that 56–60% of people respond well to active treatment with antidepressants (selective serotonin reuptake inhibitors, tricyclic antidepressants) [ 9 ]. However, pharmacotherapy may be associated with problems, such as side-effects, relapse issues, a potential duration of weeks until the medication starts working, and possible limited efficacy in mild cases [ 10 , 11 , 12 , 13 , 14 ]. Psychotherapy is also available, but access barriers can make it difficult for a number of people to get the necessary help.

Studies on depression have increased significantly over the past few decades. However, the literature remains fragmented and the interpretation of heterogeneous findings across studies and between fields is difficult. The cross-pollination of ideas between disciplines, such as genetics, neurology, immunology, and psychology, is limited. Reviews on the determinants of depression have been conducted, but they either focus exclusively on a particular set of determinants (ex. genetic risk factors [ 15 ]) or population sub-group (ex. children and adolescents [ 16 ]) or focus on characteristics measured predominantly at the individual level (ex. focus on social support, history of depression [ 17 ]) without taking the wider context (ex. area-level variables) into account. An integrated approach paying attention to key determinants from the biological, psychological, and social spheres, as well as key themes, such as the lifecourse perspective, enables clinicians and public health authorities to develop tailored, person-centred approaches.

The primary aim of this literature review: to address the aforementioned challenges, we have synthesized recent research on the biological, psychological, and social determinants of depression and we have reviewed research from fields including genetics, immunology, neurology, psychology, public health, and epidemiology, among others.

The subsidiary aim: we have paid special attention to important themes, including the lifecourse perspective and interactions between determinants, to guide further efforts by public health and medical professionals.

This literature review can be used as an evidence base by those in public health and the clinical setting and can be used to inform targeted interventions.

2. Materials and Methods

We conducted a review of the literature on the biological, psychological, and social determinants of depression in the last 4 years. We decided to focus on these determinants after discussions with academics (from the Manchester Metropolitan University, University of Cardiff, University of Colorado, Boulder, University of Cork, University of Leuven, University of Texas), charity representatives, and people with lived experience at workshops held by the University of Cambridge in 2020. In several aspects, we attempted to conduct this review according to PRISMA guidelines [ 18 ].

The inclusion and exclusion criteria are the following:

• - We included documents, such as primary studies, literature reviews, systematic reviews, meta-analyses, reports, and commentaries on the determinants of depression. The determinants refer to variables that appear to be linked to the development of depression, such as physiological factors (e.g., the nervous system, genetics), but also factors that are further away or more distal to the condition. Determinants may be risk or protective factors, and individual- or wider-area-level variables.
• - We focused on major depressive disorder, treatment-resistant depression, dysthymia, depressive symptoms, poststroke depression, perinatal depression, as well as depressive-like behaviour (common in animal studies), among others.
• - We included papers regardless of the measurement methods of depression.
• - We included papers that focused on human and/or rodent research.
• - This review focused on articles written in the English language.
• - Documents published between 2017–2020 were captured to provide an understanding of the latest research on this topic.
• - Studies that assessed depression as a comorbidity or secondary to another disorder.
• - Studies that did not focus on rodent and/or human research.
• - Studies that focused on the treatment of depression. We made this decision, because this is an in-depth topic that would warrant a separate stand-alone review.
• Next, we searched PubMed (2017–2020) using keywords related to depression and determinants. Appendix A contains the search strategy used. We also conducted focused searches in Medline, Scopus, and PsycInfo (2017–2020).
• Once the documents were identified through the databases, the inclusion and exclusion criteria were applied to the titles and abstracts. Screening of documents was conducted by O.R., and a subsample was screened by J.M.; any discrepancies were resolved through a communication process.
• The full texts of documents were retrieved, and the inclusion and exclusion criteria were again applied. A subsample of documents underwent double screening by two authors (O.R., J.M.); again, any discrepancies were resolved through communication.
• a. A data charting form was created to capture the data elements of interest, including the authors, titles, determinants (biological, psychological, social), and the type of depression assessed by the research (e.g., major depression, depressive symptoms, depressive behaviour).
• b. The data charting form was piloted on a subset of documents, and refinements to it were made. The data charting form was created with the data elements described above and tested in 20 studies to determine whether refinements in the wording or language were needed.
• c. Data charting was conducted on the documents.
• d. Narrative analysis was conducted on the data charting table to identify key themes. When a particular finding was noted more than once, it was logged as a potential theme, with a review of these notes yielding key themes that appeared on multiple occasions. When key themes were identified, one researcher (O.R.) reviewed each document pertaining to that theme and derived concepts (key determinants and related outcomes). This process (a subsample) was verified by a second author (J.M.), and the two authors resolved any discrepancies through communication. Key themes were also checked as to whether they were of major significance to public mental health and at the forefront of public health discourse according to consultations we held with stakeholders from the Manchester Metropolitan University, University of Cardiff, University of Colorado, Boulder, University of Cork, University of Leuven, University of Texas, charity representatives, and people with lived experience at workshops held by the University of Cambridge in 2020.

We condensed the extensive information gleaned through our review into short summaries (with key points boxes for ease of understanding and interpretation of the data).

Through the searches, 6335 documents, such as primary studies, literature reviews, systematic reviews, meta-analyses, reports, and commentaries, were identified. After applying the inclusion and exclusion criteria, 470 papers were included in this review ( Supplementary Table S1 ). We focused on aspects related to biological, psychological, and social determinants of depression (examples of determinants and related outcomes are provided under each of the following sections.

3.1. Biological Factors

The following aspects will be discussed in this section: physical health conditions; then specific biological factors, including genetics; the microbiome; inflammatory factors; stress and hypothalamic–pituitary–adrenal (HPA) axis dysfunction, and the kynurenine pathway. Finally, aspects related to cognition will also be discussed in the context of depression.

3.1.1. Physical Health Conditions

Studies on physical health conditions—key points:

• The presence of a physical health condition can increase the risk for depression
• Psychological evaluation in physically sick populations is needed
• There is large heterogeneity in study design and measurement; this makes the comparison of findings between and across studies difficult

A number of studies examined the links between the outcome of depression and physical health-related factors, such as bladder outlet obstruction, cerebral atrophy, cataract, stroke, epilepsy, body mass index and obesity, diabetes, urinary tract infection, forms of cancer, inflammatory bowel disorder, glaucoma, acne, urea accumulation, cerebral small vessel disease, traumatic brain injury, and disability in multiple sclerosis [ 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 ]. For example, bladder outlet obstruction has been linked to inflammation and depressive behaviour in rodent research [ 24 ]. The presence of head and neck cancer also seemed to be related to an increased risk for depressive disorder [ 45 ]. Gestational diabetes mellitus has been linked to depressive symptoms in the postpartum period (but no association has been found with depression in the third pregnancy trimester) [ 50 ], and a plethora of other such examples of relationships between depression and physical conditions exist. As such, the assessment of psychopathology and the provision of support are necessary in individuals of ill health [ 45 ]. Despite the large evidence base on physical health-related factors, differences in study methodology and design, the lack of standardization when it comes to the measurement of various physical health conditions and depression, and heterogeneity in the study populations makes it difficult to compare studies [ 50 ].

The next subsections discuss specific biological factors, including genetics; the microbiome; inflammatory factors; stress and hypothalamic–pituitary–adrenal (HPA) axis dysfunction, and the kynurenine pathway; and aspects related to cognition.

3.1.2. Genetics

Studies on genetics—key points:

There were associations between genetic factors and depression; for example:

• The brain-derived neurotrophic factor (BDNF) plays an important role in depression
• Links exist between major histocompatibility complex region genes, as well as various gene polymorphisms and depression
• Single nucleotide polymorphisms (SNPs) of genes involved in the tryptophan catabolites pathway are of interest in relation to depression

A number of genetic-related factors, genomic regions, polymorphisms, and other related aspects have been examined with respect to depression [ 61 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 94 , 95 , 96 , 97 , 98 , 99 , 100 , 101 , 102 , 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 , 113 , 114 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 , 125 , 126 , 127 , 128 , 129 , 130 , 131 , 132 , 133 , 134 , 135 , 136 , 137 , 138 , 139 , 140 ]. The influence of BDNF in relation to depression has been amply studied [ 117 , 118 , 141 , 142 , 143 ]. Research has shown associations between depression and BDNF (as well as candidate SNPs of the BDNF gene, polymorphisms of the BDNF gene, and the interaction of these polymorphisms with other determinants, such as stress) [ 129 , 144 , 145 ]. Specific findings have been reported: for example, a study reported a link between the BDNF rs6265 allele (A) and major depressive disorder [ 117 ].

Other research focused on major histocompatibility complex region genes, endocannabinoid receptor gene polymorphisms, as well as tissue-specific genes and gene co-expression networks and their links to depression [ 99 , 110 , 112 ]. The SNPs of genes involved in the tryptophan catabolites pathway have also been of interest when studying the pathogenesis of depression.

The results from genetics studies are compelling; however, the findings remain mixed. One study indicated no support for depression candidate gene findings [ 122 ]. Another study found no association between specific polymorphisms and major depressive disorder [ 132 ]. As such, further research using larger samples is needed to corroborate the statistically significant associations reported in the literature.

3.1.3. Microbiome

Studies on the microbiome—key points:

• The gut bacteria and the brain communicate via both direct and indirect pathways called the gut-microbiota-brain axis (the bidirectional communication networks between the central nervous system and the gastrointestinal tract; this axis plays an important role in maintaining homeostasis).
• A disordered microbiome can lead to inflammation, which can then lead to depression
• There are possible links between the gut microbiome, host liver metabolism, brain inflammation, and depression

The common themes of this review have focused on the microbiome/microbiota or gut metabolome [ 146 , 147 , 148 , 149 , 150 , 151 , 152 , 153 , 154 , 155 , 156 , 157 , 158 , 159 , 160 , 161 ], the microbiota-gut-brain axis, and related factors [ 152 , 162 , 163 , 164 , 165 , 166 , 167 ]. When there is an imbalance in the intestinal bacteria, this can interfere with emotional regulation and contribute to harmful inflammatory processes and mood disorders [ 148 , 151 , 153 , 155 , 157 ]. Rodent research has shown that there may be a bidirectional association between the gut microbiota and depression: a disordered gut microbiota can play a role in the onset of this mental health problem, but, at the same time, the existence of stress and depression may also lead to a lower level of richness and diversity in the microbiome [ 158 ].

Research has also attempted to disentangle the links between the gut microbiome, host liver metabolism, brain inflammation, and depression, as well as the role of the ratio of lactobacillus to clostridium [ 152 ]. The literature has also examined the links between medication, such as antibiotics, and mood and behaviour, with the findings showing that antibiotics may be related to depression [ 159 , 168 ]. The links between the microbiome and depression are complex, and further studies are needed to determine the underpinning causal mechanisms.

3.1.4. Inflammation

Studies on inflammation—key points:

• Pro-inflammatory cytokines are linked to depression
• Pro-inflammatory cytokines, such as the tumour necrosis factor (TNF)-alpha, may play an important role
• Different methods of measurement are used, making the comparison of findings across studies difficult

Inflammation has been a theme in this literature review [ 60 , 161 , 164 , 169 , 170 , 171 , 172 , 173 , 174 , 175 , 176 , 177 , 178 , 179 , 180 , 181 , 182 , 183 , 184 ]. The findings show that raised levels of inflammation (because of factors such as pro-inflammatory cytokines) have been associated with depression [ 60 , 161 , 174 , 175 , 178 ]. For example, pro-inflammatory cytokines, such as tumour necrosis factor (TNF)-alpha, have been linked to depression [ 185 ]. Various determinants, such as early life stress, have also been linked to systemic inflammation, and this can increase the risk for depression [ 186 ].

Nevertheless, not everyone with elevated inflammation develops depression; therefore, this is just one route out of many linked to pathogenesis. Despite the compelling evidence reported with respect to inflammation, it is difficult to compare the findings across studies because of different methods used to assess depression and its risk factors.

3.1.5. Stress and HPA Axis Dysfunction

Studies on stress and HPA axis dysfunction—key points:

• Stress is linked to the release of proinflammatory factors
• The dysregulation of the HPA axis is linked to depression
• Determinants are interlinked in a complex web of causation

Stress was studied in various forms in rodent populations and humans [ 144 , 145 , 155 , 174 , 176 , 180 , 185 , 186 , 187 , 188 , 189 , 190 , 191 , 192 , 193 , 194 , 195 , 196 , 197 , 198 , 199 , 200 , 201 , 202 , 203 , 204 , 205 , 206 , 207 , 208 , 209 , 210 , 211 ].

Although this section has some overlap with others (as is to be expected because all of these determinants and body systems are interlinked), a number of studies have focused on the impact of stress on mental health. Stress has been mentioned in the literature as a risk factor of poor mental health and has emerged as an important determinant of depression. The effects of this variable are wide-ranging, and a short discussion is warranted.

Stress has been linked to the release of inflammatory factors, as well as the development of depression [ 204 ]. When the stress is high or lasts for a long period of time, this may negatively impact the brain. Chronic stress can impact the dendrites and synapses of various neurons, and may be implicated in the pathway leading to major depressive disorder [ 114 ]. As a review by Uchida et al. indicates, stress may be associated with the “dysregulation of neuronal and synaptic plasticity” [ 114 ]. Even in rodent studies, stress has a negative impact: chronic and unpredictable stress (and other forms of tension or stress) have been linked to unusual behaviour and depression symptoms [ 114 ].

The depression process and related brain changes, however, have also been linked to the hyperactivity or dysregulation of the HPA axis [ 127 , 130 , 131 , 182 , 212 ]. One review indicates that a potential underpinning mechanism of depression relates to “HPA axis abnormalities involved in chronic stress” [ 213 ]. There is a complex relationship between the HPA axis, glucocorticoid receptors, epigenetic mechanisms, and psychiatric sequelae [ 130 , 212 ].

In terms of the relationship between the HPA axis and stress and their influence on depression, the diathesis–stress model offers an explanation: it could be that early stress plays a role in the hyperactivation of the HPA axis, thus creating a predisposition “towards a maladaptive reaction to stress”. When this predisposition then meets an acute stressor, depression may ensue; thus, in line with the diathesis–stress model, a pre-existing vulnerability and stressor can create fertile ground for a mood disorder [ 213 ]. An integrated review by Dean and Keshavan [ 213 ] suggests that HPA axis hyperactivity is, in turn, related to other determinants, such as early deprivation and insecure early attachment; this again shows the complex web of causation between the different determinants.

3.1.6. Kynurenine Pathway

Studies on the kynurenine pathway—key points:

• The kynurenine pathway is linked to depression
• Indolamine 2,3-dioxegenase (IDO) polymorphisms are linked to postpartum depression

The kynurenine pathway was another theme that emerged in this review [ 120 , 178 , 181 , 184 , 214 , 215 , 216 , 217 , 218 , 219 , 220 , 221 ]. The kynurenine pathway has been implicated not only in general depressed mood (inflammation-induced depression) [ 184 , 214 , 219 ] but also postpartum depression [ 120 ]. When the kynurenine metabolism pathway is activated, this results in metabolites, which are neurotoxic.

A review by Jeon et al. notes a link between the impairment of the kynurenine pathway and inflammation-induced depression (triggered by treatment for various physical diseases, such as malignancy). The authors note that this could represent an important opportunity for immunopharmacology [ 214 ]. Another review by Danzer et al. suggests links between the inflammation-induced activation of indolamine 2,3-dioxegenase (the enzyme that converts tryptophan to kynurenine), the kynurenine metabolism pathway, and depression, and also remarks about the “opportunities for treatment of inflammation-induced depression” [ 184 ].

3.1.7. Cognition

Studies on cognition and the brain—key points:

• Cognitive decline and cognitive deficits are linked to increased depression risk
• Cognitive reserve is important in the disability/depression relationship
• Family history of cognitive impairment is linked to depression

A number of studies have focused on the theme of cognition and the brain. The results show that factors, such as low cognitive ability/function, cognitive vulnerability, cognitive impairment or deficits, subjective cognitive decline, regression of dendritic branching and hippocampal atrophy/death of hippocampal cells, impaired neuroplasticity, and neurogenesis-related aspects, have been linked to depression [ 131 , 212 , 222 , 223 , 224 , 225 , 226 , 227 , 228 , 229 , 230 , 231 , 232 , 233 , 234 , 235 , 236 , 237 , 238 , 239 ]. The cognitive reserve appears to act as a moderator and can magnify the impact of certain determinants on poor mental health. For example, in a study in which participants with multiple sclerosis also had low cognitive reserve, disability was shown to increase the risk for depression [ 63 ]. Cognitive deficits can be both causal and resultant in depression. A study on individuals attending outpatient stroke clinics showed that lower scores in cognition were related to depression; thus, cognitive impairment appears to be associated with depressive symptomatology [ 226 ]. Further, Halahakoon et al. [ 222 ] note a meta-analysis [ 240 ] that shows that a family history of cognitive impairment (in first degree relatives) is also linked to depression.

In addition to cognitive deficits, low-level cognitive ability [ 231 ] and cognitive vulnerability [ 232 ] have also been linked to depression. While cognitive impairment may be implicated in the pathogenesis of depressive symptoms [ 222 ], negative information processing biases are also important; according to the ‘cognitive neuropsychological’ model of depression, negative affective biases play a central part in the development of depression [ 222 , 241 ]. Nevertheless, the evidence on this topic is mixed and further work is needed to determine the underpinning mechanisms between these states.

3.2. Psychological Factors

Studies on psychological factors—key points:

• There are many affective risk factors linked to depression
• Determinants of depression include negative self-concept, sensitivity to rejection, neuroticism, rumination, negative emotionality, and others

A number of studies have been undertaken on the psychological factors linked to depression (including mastery, self-esteem, optimism, negative self-image, current or past mental health conditions, and various other aspects, including neuroticism, brooding, conflict, negative thinking, insight, cognitive fusion, emotional clarity, rumination, dysfunctional attitudes, interpretation bias, and attachment style) [ 66 , 128 , 140 , 205 , 210 , 228 , 235 , 242 , 243 , 244 , 245 , 246 , 247 , 248 , 249 , 250 , 251 , 252 , 253 , 254 , 255 , 256 , 257 , 258 , 259 , 260 , 261 , 262 , 263 , 264 , 265 , 266 , 267 , 268 , 269 , 270 , 271 , 272 , 273 , 274 , 275 , 276 , 277 , 278 , 279 , 280 , 281 , 282 , 283 , 284 , 285 , 286 , 287 , 288 , 289 , 290 ]. Determinants related to this condition include low self-esteem and shame, among other factors [ 269 , 270 , 275 , 278 ]. Several emotional states and traits, such as neuroticism [ 235 , 260 , 271 , 278 ], negative self-concept (with self-perceptions of worthlessness and uselessness), and negative interpretation or attention biases have been linked to depression [ 261 , 271 , 282 , 283 , 286 ]. Moreover, low emotional clarity has been associated with depression [ 267 ]. When it comes to the severity of the disorder, it appears that meta-emotions (“emotions that occur in response to other emotions (e.g., guilt about anger)” [ 268 ]) have a role to play in depression [ 268 ].

A determinant that has received much attention in mental health research concerns rumination. Rumination has been presented as a mediator but also as a risk factor for depression [ 57 , 210 , 259 ]. When studied as a risk factor, it appears that the relationship of rumination with depression is mediated by variables that include limited problem-solving ability and insufficient social support [ 259 ]. However, rumination also appears to act as a mediator: for example, this variable (particularly brooding rumination) lies on the causal pathway between poor attention control and depression [ 265 ]. This shows that determinants may present in several forms: as moderators or mediators, risk factors or outcomes, and this is why disentangling the relationships between the various factors linked to depression is a complex task.

The psychological determinants are commonly researched variables in the mental health literature. A wide range of factors have been linked to depression, such as the aforementioned determinants, but also: (low) optimism levels, maladaptive coping (such as avoidance), body image issues, and maladaptive perfectionism, among others [ 269 , 270 , 272 , 273 , 275 , 276 , 279 , 285 , 286 ]. Various mechanisms have been proposed to explain the way these determinants increase the risk for depression. One of the underpinning mechanisms linking the determinants and depression concerns coping. For example, positive fantasy engagement, cognitive biases, or personality dispositions may lead to emotion-focused coping, such as brooding, and subsequently increase the risk for depression [ 272 , 284 , 287 ]. Knowing the causal mechanisms linking the determinants to outcomes provides insight for the development of targeted interventions.

3.3. Social Determinants

Studies on social determinants—key points:

• Social determinants are the conditions in the environments where people are born, live, learn, work, play, etc.; these influence (mental) health [ 291 ]
• There are many social determinants linked to depression, such as sociodemographics, social support, adverse childhood experiences
• Determinants can be at the individual, social network, community, and societal levels

Studies also focused on the social determinants of (mental) health; these are the conditions in which people are born, live, learn, work, play, and age, and have a significant influence on wellbeing [ 291 ]. Factors such as age, social or socioeconomic status, social support, financial strain and deprivation, food insecurity, education, employment status, living arrangements, marital status, race, childhood conflict and bullying, violent crime exposure, abuse, discrimination, (self)-stigma, ethnicity and migrant status, working conditions, adverse or significant life events, illiteracy or health literacy, environmental events, job strain, and the built environment have been linked to depression, among others [ 52 , 133 , 235 , 236 , 239 , 252 , 269 , 280 , 292 , 293 , 294 , 295 , 296 , 297 , 298 , 299 , 300 , 301 , 302 , 303 , 304 , 305 , 306 , 307 , 308 , 309 , 310 , 311 , 312 , 313 , 314 , 315 , 316 , 317 , 318 , 319 , 320 , 321 , 322 , 323 , 324 , 325 , 326 , 327 , 328 , 329 , 330 , 331 , 332 , 333 , 334 , 335 , 336 , 337 , 338 , 339 , 340 , 341 , 342 , 343 , 344 , 345 , 346 , 347 , 348 , 349 , 350 , 351 , 352 , 353 , 354 , 355 , 356 , 357 , 358 , 359 , 360 , 361 , 362 , 363 , 364 , 365 , 366 , 367 , 368 , 369 , 370 , 371 ]. Social support and cohesion, as well as structural social capital, have also been identified as determinants [ 140 , 228 , 239 , 269 , 293 , 372 , 373 , 374 , 375 , 376 , 377 , 378 , 379 ]. In a study, part of the findings showed that low levels of education have been shown to be linked to post-stroke depression (but not severe or clinical depression outcomes) [ 299 ]. A study within a systematic review indicated that having only primary education was associated with a higher risk of depression compared to having secondary or higher education (although another study contrasted this finding) [ 296 ]. Various studies on socioeconomic status-related factors have been undertaken [ 239 , 297 ]; the research has shown that a low level of education is linked to depression [ 297 ]. Low income is also related to depressive disorders [ 312 ]. By contrast, high levels of education and income are protective [ 335 ].

A group of determinants touched upon by several studies included adverse childhood or early life experiences: ex. conflict with parents, early exposure to traumatic life events, bullying and childhood trauma were found to increase the risk of depression (ex. through pathways, such as inflammation, interaction effects, or cognitive biases) [ 161 , 182 , 258 , 358 , 362 , 380 ].

Gender-related factors were also found to play an important role with respect to mental health [ 235 , 381 , 382 , 383 , 384 , 385 ]. Gender inequalities can start early on in the lifecourse, and women were found to be twice as likely to have depression as men. Gender-related factors were linked to cognitive biases, resilience and vulnerabilities [ 362 , 384 ].

Determinants can impact mental health outcomes through underpinning mechanisms. For example, harmful determinants can influence the uptake of risk behaviours. Risk behaviours, such as sedentary behaviour, substance abuse and smoking/nicotine exposure, have been linked to depression [ 226 , 335 , 355 , 385 , 386 , 387 , 388 , 389 , 390 , 391 , 392 , 393 , 394 , 395 , 396 , 397 , 398 , 399 , 400 , 401 ]. Harmful determinants can also have an impact on diet. Indeed, dietary aspects and diet components (ex. vitamin D, folate, selenium intake, iron, vitamin B12, vitamin K, fiber intake, zinc) as well as diet-related inflammatory potential have been linked to depression outcomes [ 161 , 208 , 236 , 312 , 396 , 402 , 403 , 404 , 405 , 406 , 407 , 408 , 409 , 410 , 411 , 412 , 413 , 414 , 415 , 416 , 417 , 418 , 419 , 420 , 421 , 422 , 423 , 424 , 425 , 426 , 427 , 428 ]. A poor diet has been linked to depression through mechanisms such as inflammation [ 428 ].

Again, it is difficult to constrict diet to the ‘social determinants of health’ category as it also relates to inflammation (biological determinants) and could even stand alone as its own category. Nevertheless, all of these factors are interlinked and influence one another in a complex web of causation, as mentioned elsewhere in the paper.

Supplementary Figure S1 contains a representation of key determinants acting at various levels: the individual, social network, community, and societal levels. The determinants have an influence on risk behaviours, and this, in turn, can affect the mood (i.e., depression), body processes (ex. can increase inflammation), and may negatively influence brain structure and function.

3.4. Others

Studies on ‘other’ determinants—key points:

• A number of factors are related to depression
• These may not be as easily categorized as the other determinants in this paper

A number of factors arose in this review that were related to depression; it was difficult to place these under a specific heading above, so this ‘other’ category was created. A number of these could be sorted under the ‘social determinants of depression’ category. For example, being exposed to deprivation, hardship, or adversity may increase the risk for air pollution exposure and nighttime shift work, among others, and the latter determinants have been found to increase the risk for depression. Air pollution could also be regarded as an ecologic-level (environmental) determinant of mental health.

Nevertheless, we have decided to leave these factors in a separate category (because their categorization may not be as immediately clear-cut as others), and these factors include: low-level light [ 429 ], weight cycling [ 430 ], water contaminants [ 431 ], trade [ 432 ], air pollution [ 433 , 434 ], program-level variables (ex. feedback and learning experience) [ 435 ], TV viewing [ 436 ], falls [ 437 ], various other biological factors [ 116 , 136 , 141 , 151 , 164 , 182 , 363 , 364 , 438 , 439 , 440 , 441 , 442 , 443 , 444 , 445 , 446 , 447 , 448 , 449 , 450 , 451 , 452 , 453 , 454 , 455 , 456 , 457 , 458 , 459 , 460 , 461 , 462 , 463 , 464 , 465 , 466 , 467 , 468 , 469 ], mobile phone use [ 470 ], ultrasound chronic exposure [ 471 ], nighttime shift work [ 472 ], work accidents [ 473 ], therapy enrollment [ 226 ], and exposure to light at night [ 474 ].

4. Cross-Cutting Themes

4.1. lifecourse perspective.

Studies on the lifecourse perspective—key points:

• Early life has an importance on mental health
• Stress has been linked to depression
• In old age, the decline in social capital is important

Trajectories and life events are important when it comes to the lifecourse perspective. Research has touched on the influence of prenatal or early life stress on an individual’s mental health trajectory [ 164 , 199 , 475 ]. Severe stress that occurs in the form of early-life trauma has also been associated with depressive symptoms [ 362 , 380 ]. It may be that some individuals exposed to trauma develop thoughts of personal failure, which then serve as a catalyst of depression [ 380 ].

At the other end of the life trajectory—old age—specific determinants have been linked to an increased risk for depression. Older people are at a heightened risk of losing their social networks, and structural social capital has been identified as important in relation to depression in old age [ 293 ].

4.2. Gene–Environment Interactions

Studies on gene–environment interactions—key points:

• The environment and genetics interact to increase the risk of depression
• The etiology of depression is multifactorial
• Adolescence is a time of vulnerability

A number of studies have touched on gene–environment interactions [ 72 , 77 , 82 , 119 , 381 , 476 , 477 , 478 , 479 , 480 , 481 ]. The interactions between genetic factors and determinants, such as negative life events (ex. relationship and social difficulties, serious illness, unemployment and financial crises) and stressors (ex. death of spouse, minor violations of law, neighbourhood socioeconomic status) have been studied in relation to depression [ 82 , 135 , 298 , 449 , 481 ]. A study reported an interaction of significant life events with functional variation in the serotonin-transporter-linked polymorphic region (5-HTTLPR) allele type (in the context of multiple sclerosis) and linked this to depression [ 361 ], while another reported an interaction between stress and 5-HTTLPR in relation to depression [ 480 ]. Other research reported that the genetic variation of HPA-axis genes has moderating effects on the relationship between stressors and depression [ 198 ]. Another study showed that early-life stress interacts with gene variants to increase the risk for depression [ 77 ].

Adolescence is a time of vulnerability [ 111 , 480 ]. Perceived parental support has been found to interact with genes (GABRR1, GABRR2), and this appears to be associated with depressive symptoms in adolescence [ 480 ]. It is important to pay special attention to critical periods in the lifecourse so that adequate support is provided to those who are most vulnerable.

The etiology of depression is multifactorial, and it is worthwhile to examine the interaction between multiple factors, such as epigenetic, genetic, and environmental factors, in order to truly understand this mental health condition. Finally, taking into account critical periods of life when assessing gene–environment interactions is important for developing targeted interventions.

5. Discussion

Depression is one of the most common mental health conditions, and, if left untreated, it can increase the risk for substance abuse, anxiety disorders, and suicide. In the past 20 years, a large number of studies on the risk and protective factors of depression have been undertaken in various fields, such as genetics, neurology, immunology, and epidemiology. However, there are limitations associated with the extant evidence base. The previous syntheses on depression are limited in scope and focus exclusively on social or biological factors, population sub-groups, or examine depression as a comorbidity (rather than an independent disorder). The research on the determinants and causal pathways of depression is fragmentated and heterogeneous, and this has not helped to stimulate progress when it comes to the prevention and intervention of this condition—specifically unravelling the complexity of the determinants related to this condition and thus refining the prevention and intervention methods.

The scope of this paper was to bring together the heterogeneous, vast, and fragmented literature on depression and paint a picture of the key factors that contribute to this condition. The findings from this review show that there are important themes when it comes to the determinants of depression, such as: the microbiome, dysregulation of the HPA axis, inflammatory reactions, the kynurenine pathway, as well as psychological and social factors. It may be that physical factors are proximal determinants of depression, which, in turn, are acted on by more distal social factors, such as deprivation, environmental events, and social capital.

The Marmot Report [ 291 ], the World Health Organization [ 482 ], and Compton et al. [ 483 ] highlight that the most disadvantaged segments of society are suffering (the socioeconomic context is important), and this inequality in resources has translated to inequality in mental health outcomes [ 483 ]. To tackle the issue of egalitarianism and restore equality in the health between the groups, the social determinants need to be addressed [ 483 ]. A wide range of determinants of mental health have been identified in the literature: age, gender, ethnicity, family upbringing and early attachment patterns, social support, access to food, water and proper nutrition, and community factors. People spiral downwards because of individual- and societal-level circumstances; therefore, these circumstances along with the interactions between the determinants need to be considered.

Another important theme in the mental health literature is the lifecourse perspective. This shows that the timing of events has significance when it comes to mental health. Early life is a critical period during the lifespan at which cognitive processes develop. Exposure to harmful determinants, such as stress, during this period can place an individual on a trajectory of depression in adulthood or later life. When an individual is exposed to harmful determinants during critical periods and is also genetically predisposed to depression, the risk for the disorder can be compounded. This is why aspects such as the lifecourse perspective and gene–environment interactions need to be taken into account. Insight into this can also help to refine targeted interventions.

A number of interventions for depression have been developed or recommended, addressing, for example, the physical factors described here and lifestyle modifications. Interventions targeting various factors, such as education and socioeconomic status, are needed to help prevent and reduce the burden of depression. Further research on the efficacy of various interventions is needed. Additional studies are also needed on each of the themes described in this paper, for example: the biological factors related to postpartum depression [ 134 ], and further work is needed on depression outcomes, such as chronic, recurrent depression [ 452 ]. Previous literature has shown that chronic stress (associated with depression) is also linked to glucocorticoid receptor resistance, as well as problems with the regulation of the inflammatory response [ 484 ]. Further work is needed on this and the underpinning mechanisms between the determinants and outcomes. This review highlighted the myriad ways of measuring depression and its determinants [ 66 , 85 , 281 , 298 , 451 , 485 ]. Thus, the standardization of the measurements of the outcomes (ex. a gold standard for measuring depression) and determinants is essential; this can facilitate comparisons of findings across studies.

5.1. Strengths

This paper has important strengths. It brings together the wide literature on depression and helps to bridge disciplines in relation to one of the most common mental health problems. We identified, selected, and extracted data from studies, and provided concise summaries.

5.2. Limitations

The limitations of the review include missing potentially important studies; however, this is a weakness that cannot be avoided by literature reviews. Nevertheless, the aim of the review was not to identify each study that has been conducted on the risk and protective factors of depression (which a single review is unable to capture) but rather to gain insight into the breadth of literature on this topic, highlight key biological, psychological, and social determinants, and shed light on important themes, such as the lifecourse perspective and gene–environment interactions.

6. Conclusions

We have reviewed the determinants of depression and recognize that there are a multitude of risk and protective factors at the individual and wider ecologic levels. These determinants are interlinked and influence one another. We have attempted to describe the wide literature on this topic, and we have brought to light major factors that are of public mental health significance. This review may be used as an evidence base by those in public health, clinical practice, and research.

This paper discusses key areas in depression research; however, an exhaustive discussion of all the risk factors and determinants linked to depression and their mechanisms is not possible in one journal article—which, by its very nature, a single paper cannot do. We have brought to light overarching factors linked to depression and a workable conceptual framework that may guide clinical and public health practice; however, we encourage other researchers to continue to expand on this timely and relevant work—particularly as depression is a top priority on the policy agenda now.

Acknowledgments

Thank you to Isla Kuhn for the help with the Medline, Scopus, and PsycInfo database searches.

Supplementary Materials

The following are available online at https://www.mdpi.com/article/10.3390/brainsci11121633/s1 , Figure S1: Conceptual framework: Determinants of depression, Table S1: Data charting—A selection of determinants from the literature.

Appendix A.1. Search Strategy

Search: ((((((((((((((((“Gene-Environment Interaction”[Majr]) OR (“Genetics”[Mesh])) OR (“Genome-Wide Association Study”[Majr])) OR (“Microbiota”[Mesh] OR “Gastrointestinal Microbiome”[Mesh])) OR (“Neurogenic Inflammation”[Mesh])) OR (“genetic determinant”)) OR (“gut-brain-axis”)) OR (“Kynurenine”[Majr])) OR (“Cognition”[Mesh])) OR (“Neuronal Plasticity”[Majr])) OR (“Neurogenesis”[Mesh])) OR (“Genes”[Mesh])) OR (“Neurology”[Majr])) OR (“Social Determinants of Health”[Majr])) OR (“Glucocorticoids”[Mesh])) OR (“Tryptophan”[Mesh])) AND (“Depression”[Mesh] OR “Depressive Disorder”[Mesh]) Filters: from 2017—2020.

Ovid MEDLINE(R) and Epub Ahead of Print, In-Process, In-Data-Review & Other Non-Indexed Citations, Daily and Versions(R)

• exp *Depression/
• exp *Depressive Disorder/
• exp *”Social Determinants of Health”/
• exp *Tryptophan/
• exp *Glucocorticoids/
• exp *Neurology/
• exp *Genes/
• exp *Neurogenesis/
• exp *Neuronal Plasticity/
• exp *Kynurenine/
• exp *Genetics/
• exp *Neurogenic Inflammation/
• exp *Gastrointestinal Microbiome/
• exp *Genome-Wide Association Study/
• exp *Gene-Environment Interaction/
• exp *Depression/et [Etiology]
• exp *Depressive Disorder/et
• or/4-16   637368
• limit 22 to yr = “2017–Current”
• “cause* of depression”.mp.
• “cause* of depression”.ti.
• (cause adj3 (depression or depressive)).ti.
• (caus* adj3 (depression or depressive)).ti.

Appendix A.2. PsycInfo

(TITLE ( depression OR “ Depressive Disorder ”) AND TITLE (“ Social Determinants of Health ” OR tryptophan OR glucocorticoids OR neurology OR genes OR neurogenesis OR “ Neuronal Plasticity ” OR kynurenine OR genetics OR “ Neurogenic Inflammation ” OR “ Gastrointestinal Microbiome ” OR “ Genome-Wide Association Study ” OR “ Gene-Environment Interaction ” OR aetiology OR etiology )) OR TITLE ( cause* W/3 ( depression OR depressive )).

Author Contributions

O.R. was responsible for the design of the study and methodology undertaken. Despite P.T.’s involvement in YPMH, he had no role in the design of the study; P.T. was responsible for the conceptualization of the study. Validation was conducted by O.R. and J.F.M. Formal analysis (data charting) was undertaken by O.R. O.R. and P.T. were involved in the investigation, resource acquisition, and data presentation. The original draft preparation was undertaken by O.R. The writing was conducted by O.R., with review and editing by P.T. and J.F.M. Funding acquisition was undertaken by O.R. and P.T. All authors have read and agreed to the published version of the manuscript.

This research was funded by The William Templeton Foundation for Young People’s Mental Health, Cambridge Philosophical Society, and the Aviva Foundation.

Conflicts of Interest

The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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Overcoming Teen Depression and Anxiety: Brynn’s Story

Parents don’t always recognize the symptoms of teen depression and anxiety in their son or daughter. Sometimes, teenagers themselves don’t understand what is happening to them. This is Brynn’s story of her experience with teen depression and anxiety .

A Long Descent

I have always been a quieter kid, so when I started retreating into myself my junior year, it seemed like no one noticed. I got two to four hours of sleep a night, ate infrequently, felt worthless, and began to lose interest in everything—classes, friends. As time went on, I became more and more convinced that this was just how I was. I would think about asking for help and then be afraid of being a burden on my friends and family—constantly reinforcing the idea that they did not want me around.

I woke up every morning crying and dragged myself out of bed, feeling like I was carrying around a 50-pound backpack.

Despite this, I kept up my grades and my parents had no idea what was happening; they were frustrated with me for being “too sensitive.”

That winter, I began wanting to hurt myself. I finally worked up the courage to say something to my mom, and she was adamant it was just PMS. My confidence was crushed. And my symptoms only got worse. My relationship with my parents deteriorated as we fought more and more. My siblings, whom I used to be so close with, now asked me “where the old Brynn was” when I snapped at them. It took all my energy just to get through the day.

Eventually that summer, I confessed to my friends how I had been feeling—the worthlessness, the suicidal thoughts. But what could they do? I was entrusting them with something way too important and complicated for 16-year-olds to handle. As the summer went by, I became increasingly fixated on my weight, weighing myself daily, over-exercising, and restricting myself to one meal a day.

Then it was time for school again. I felt crushed and helpless with all the pressures of college admissions, my job, orchestra, good grades, a varsity sport. That’s when the anxiety attacks started. In a way, I think they saved me.

The overwhelming shaking and hyperventilating was something physical my parents could see, and that’s when they urged me to see the school guidance counselor. She almost immediately referred me to a therapist who right away saw the bigger issue— depression .

Recovery is Ongoing

My journey to health started there, but it was—and is—far from over. Because of my depression, I started hurting myself and binging. During my senior year, I spent almost three months out of school in the hospital and various therapy programs for teen depression and anxiety . We struggled over and over to find the right combination of meds that would take the edge off my symptoms. By spring, we did find the right “cocktail,” and that is when I turned the corner.

I will be struggling with depression and anxiety for life, but there is hope for me and other victims of these mental disorders. If anything in my story resonated with you, I urge you to tell a trusted adult about the problems that you are having. There is never any harm in talking to the school guidance counselors; they proved to be an invaluable resource to me over the course of my high school experience.

If a friend or family member has talked to you about experiencing anything like this, know that they can get help. Mental health disorders like teen depression and anxiety are not symbols of weakness; they are serious illnesses that can be treated with therapy and medicine. I got through high school, and I am proud to be going to college next year.

*author’s first name

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Recognizing the Lesser-Known Symptoms of Depression

February 09, 2022

By Ginger Robertson

Thanks to sensationalized media depictions of mental illness and stigma surrounding mental health conditions, people tend to have a limited view of what depression actually looks like. When you think of a “depressed person,” perhaps you envision an image from a movie or medication commercial: Someone lying alone in a dark room, crying into a box of tissues, overcome with feelings of hopelessness.

This picture is not necessarily inaccurate; it is simply incomplete. There are many more manifestations of depression — symptoms that aren’t necessarily visible or immediately obvious.

Knowing the seldom discussed symptoms of depression is a valuable skill; being able to recognize the less obvious signs may help you or a loved one identify and seek treatment for depression, if needed. Additionally, knowing and fully understanding these symptoms allows us to be more compassionate and helpful to those who are living with mental health conditions.

Here are a few lesser-known symptoms to look out for:

Studies have shown that depression can reduce cognitive functions , including working memory, long-term memory, decision making and ability to focus. Research also suggests that people with depression often have “widespread grey matter structural abnormalities” in the brain — observable structural differences that contribute to such cognitive deficits.

This often presents in what we refer to as a “brain fog,” in which people may experience an inability to focus on tasks, slower reaction times, forgetfulness and feelings of being mentally “blocked.” Naturally, this can lead to a number of professional, personal and emotional challenges; combating cognitive symptoms can be a frustrating and demoralizing experience.

If this is a symptom you have observed in yourself or someone else, remember to have patience; you and those around you are deserving of grace while navigating a health issue.

Substance Use

While substance use disorders are complex conditions, they are often linked to depression . People experiencing substance use challenges often face the consequences of misinformation and stigma; many are blamed for “poor choices” and irresponsibility.

However, this misguided discourse fails to recognize many of the facets of addiction, including the fact that many people misuse drugs and alcohol to self-medicate their depression. They may not be aware that they are depressed, may not have the resources to treat their depression or may grapple with the stigma surrounding seeking help.

We all have a role to play in dismantling stigma surrounding treatment for mental health conditions; if we can acknowledge that mental health is health, seek help ourselves and encourage others to follow suit, we may, in result, see a decline in substance use.

Weight Changes

While weight changes can be indicative of a shift in physical health, they can also be connected to mental health. Depression is known to affect appetite; some people with depression experience increased appetite and report eating more, while others experience a decrease in appetite and undereat. Accordingly, large weight fluctuations may be a symptom of unmanaged depression.

The challenge of coping with depression is often compounded by stigma surrounding weight and body size; one person may be “fat shamed” for their weight gain while another is praised for their weight loss, despite both weight changes being a result of mental illness. Overeating and undereating — and grappling with public opinion about bodies — only adds to the physical and emotional challenges of depression. A holistic approach to treating depression requires a degree of body positivity: An acceptance of all sizes with the goal of mind and body health.

Irritability

Irritability , anger and impatience often accompany depression. Perhaps you have experienced the surprise of these negative emotions that seemingly “come out of nowhere” — either when you experience them or are on the receiving end of an outburst from someone else.

Often, these outbursts are referred to as anger attacks , sudden intense spells of anger could be considered uncharacteristic and inappropriate in the moment. In turn, this can lead to feelings of shame and confusion surrounding an inability to control these intense emotions. A 2009 study found that angry reactions in depressed individuals may stem from rejection, guilt, fear and “ineffective management of the experience and expression of anger.”

While this experience can be distressing, sharing your concerns with a trusted health care professional could prevent further attacks.

Extreme Fatigue

Often, the chemical imbalances that accompany depression can strip people of their energy. Individuals with depression often have low levels of norepinephrine, serotonin and dopamine. Without appropriate levels of these chemicals, we can experience fatigue, sleep issues, low motivation, decreased interest in once-enjoyed activities and a general lack of joy.

For these reasons, many antidepressants work to increase these chemicals in the body.

From the outside, these symptoms may be judged as a personal failing. Perhaps someone appears lazy, disorganized or unclean — but in reality, they are doing their very best to cope when they are struggling to simply get out of bed. In these moments, chores may go undone, hygiene may falter and basic tasks may get overlooked.

Rather than passing judgment or demanding change, we need to remember that, often, compassion and medical intervention are the appropriate response.

Physical Pain

Other possible physical manifestations of depression are vague aches and pains. The chemicals serotonin and norepinephrine don’t simply affect mood — they also influence how we feel pain. Accordingly, the chemical imbalance linked to depression is also linked to many types of physical pain.

Additionally, research shows that there are biological factors that increase inflammation and decrease immunity during depressive episodes. Those with depression may experience headaches, body aches and stomach aches, among other ailments.

Ultimately, it’s important to remember that depression is complex. It is a mental health condition that doesn’t always look like the tired trope we see played out in the media and stigma-laden conversations.

Depression manifests in a wide variety of symptoms — both mental and physical — that most people may not be aware of. Of course, it is certainly possible to experience brain fog, misuse substances, battle fatigue and feel pain without having depression. But if you are noticing these behaviors and feelings in yourself or someone else, remain vigilant and consider seeking help. Prioritizing your health is not only wise; it is brave.

Ginger Robertson is a registered nurse and mental health blogger. She hopes her work can end the stigma surrounding mental illness and seeking mental health care.

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3 Things Not to Say to Someone Struggling With Depression

Boosting someone with depression is lifting them up without dragging them down..

Posted April 21, 2024 | Reviewed by Jessica Schrader

• What Is Depression?
• Find counselling to overcome depression
• Sometimes we can inadvertently say things that worsen the situation for someone struggling with depression.
• Telling someone with depression to "snap out of it" implies that their condition is a matter of willpower.
• Encouraging someone with depression to "just be positive" oversimplifies the complexity of their condition.

Depression is a serious mental health condition that affects millions of people worldwide. While well-intentioned, sometimes we can inadvertently say things that can worsen the situation for someone struggling with depression. It's crucial to be mindful of our words and actions when supporting loved ones dealing with depression.

Below are three things not to say inspired by real-life examples from my counseling practice (names have been changed to protect privacy).

1. "Just Snap Out of It"—Emily's Struggle

"Emily, why can't you just snap out of it?" Emily's mother exclaimed in frustration, her tone tinged with exasperation. Emily had been battling depression for months, finding it increasingly challenging to engage in daily activities or feel any sense of joy. Hearing her mother's words only deepened her feelings of inadequacy and hopelessness.

Why it's harmful

Telling someone with depression to "snap out of it" implies that their condition is a choice or a matter of willpower . Depression is a complex mental health issue influenced by various biological, psychological, and environmental factors. Such comments dismiss the severity of the illness and invalidate the individual's struggles, making them feel misunderstood and unsupported.

Alternative approach

Instead of minimizing the person's experience, offer empathy and understanding. You could say, "I'm here for you, Emily. It's OK to feel this way, and I want to support you through it. Let's find ways together to help you feel better."

2. "You Have Nothing to Be Depressed About"—Alex's Dilemma

"But Alex, you have such a good life. Why are you so depressed all the time?" Sarah, Alex's friend, questioned with a puzzled expression. Alex had a successful career , a loving family, and a stable relationship, yet the weight of depression seemed insurmountable.

When researching my book, The Anxiety , Depression, & Anger Toolbox for Teens , I saw a lot of research supporting how depression doesn't discriminate based on external circumstances. Even people with seemingly perfect lives can struggle with depression. Invalidating someone's feelings by suggesting they have no reason to be depressed can amplify their guilt and shame . It may also deter them from seeking help, fearing they will not be understood or believed.

Acknowledge that depression can affect anyone, regardless of their life situation. Offer your support by saying, "I understand that depression doesn't always have a clear cause, Alex. You don't have to go through this alone. I'm here to listen whenever you need to talk."

3. "Just Be Positive"—James' Experience

"James, you need to think more positively. Stop dwelling on the negative all the time," remarked David, James' colleague, during a team meeting. James struggled to maintain a facade of normalcy at work, concealing the overwhelming despair that consumed him daily.

Encouraging someone with depression to "just be positive" oversimplifies the complexity of their condition. Depression is not a choice, and simply changing one's mindset cannot alleviate its symptoms. Such comments can intensify feelings of inadequacy and failure, reinforcing the belief that the individual is somehow responsible for their suffering.

Express your concern and willingness to support without imposing unrealistic expectations. You could say, "James, I've noticed you've been having a tough time lately. I'm here to listen if you ever need to talk or if there's anything I can do to help lighten your load."

Concluding Thoughts

Supporting someone with depression requires sensitivity, empathy, and understanding. Avoiding these three harmful statements can create a more supportive environment for individuals struggling with mental illness. Instead, offer unconditional support, validate their experiences, and encourage them to seek professional help when needed. Together, we can contribute to a culture of compassion and acceptance for those battling depression.

To find a therapist, please visit the Psychology Today Therapy Directory .

Jeffrey Bernstein, Ph.D. , is a psychologist and the author of seven books, including 10 Days to a Less Defiant Child.

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