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50+ Research Topics for Psychology Papers

How to Find Psychology Research Topics for Your Student Paper

Kendra Cherry, MS, is a psychosocial rehabilitation specialist, psychology educator, and author of the "Everything Psychology Book."

new topics for psychology research

Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital.

new topics for psychology research

  • Specific Branches of Psychology
  • Topics Involving a Disorder or Type of Therapy
  • Human Cognition
  • Human Development
  • Critique of Publications
  • Famous Experiments
  • Historical Figures
  • Specific Careers
  • Case Studies
  • Literature Reviews
  • Your Own Study/Experiment

Are you searching for a great topic for your psychology paper ? Sometimes it seems like coming up with topics of psychology research is more challenging than the actual research and writing. Fortunately, there are plenty of great places to find inspiration and the following list contains just a few ideas to help get you started.

Finding a solid topic is one of the most important steps when writing any type of paper. It can be particularly important when you are writing a psychology research paper or essay. Psychology is such a broad topic, so you want to find a topic that allows you to adequately cover the subject without becoming overwhelmed with information.

I can always tell when a student really cares about the topic they chose; it comes through in the writing. My advice is to choose a topic that genuinely interests you, so you’ll be more motivated to do thorough research.

In some cases, such as in a general psychology class, you might have the option to select any topic from within psychology's broad reach. Other instances, such as in an  abnormal psychology  course, might require you to write your paper on a specific subject such as a psychological disorder.

As you begin your search for a topic for your psychology paper, it is first important to consider the guidelines established by your instructor.

Research Topics Within Specific Branches of Psychology

The key to selecting a good topic for your psychology paper is to select something that is narrow enough to allow you to really focus on the subject, but not so narrow that it is difficult to find sources or information to write about.

One approach is to narrow your focus down to a subject within a specific branch of psychology. For example, you might start by deciding that you want to write a paper on some sort of social psychology topic. Next, you might narrow your focus down to how persuasion can be used to influence behavior .

Other social psychology topics you might consider include:

  • Prejudice and discrimination (i.e., homophobia, sexism, racism)
  • Social cognition
  • Person perception
  • Social control and cults
  • Persuasion, propaganda, and marketing
  • Attraction, romance, and love
  • Nonverbal communication
  • Prosocial behavior

Psychology Research Topics Involving a Disorder or Type of Therapy

Exploring a psychological disorder or a specific treatment modality can also be a good topic for a psychology paper. Some potential abnormal psychology topics include specific psychological disorders or particular treatment modalities, including:

  • Eating disorders
  • Borderline personality disorder
  • Seasonal affective disorder
  • Schizophrenia
  • Antisocial personality disorder
  • Profile a  type of therapy  (i.e., cognitive-behavioral therapy, group therapy, psychoanalytic therapy)

Topics of Psychology Research Related to Human Cognition

Some of the possible topics you might explore in this area include thinking, language, intelligence, and decision-making. Other ideas might include:

  • False memories
  • Speech disorders
  • Problem-solving

Topics of Psychology Research Related to Human Development

In this area, you might opt to focus on issues pertinent to  early childhood  such as language development, social learning, or childhood attachment or you might instead opt to concentrate on issues that affect older adults such as dementia or Alzheimer's disease.

Some other topics you might consider include:

  • Language acquisition
  • Media violence and children
  • Learning disabilities
  • Gender roles
  • Child abuse
  • Prenatal development
  • Parenting styles
  • Aspects of the aging process

Do a Critique of Publications Involving Psychology Research Topics

One option is to consider writing a critique paper of a published psychology book or academic journal article. For example, you might write a critical analysis of Sigmund Freud's Interpretation of Dreams or you might evaluate a more recent book such as Philip Zimbardo's  The Lucifer Effect: Understanding How Good People Turn Evil .

Professional and academic journals are also great places to find materials for a critique paper. Browse through the collection at your university library to find titles devoted to the subject that you are most interested in, then look through recent articles until you find one that grabs your attention.

Topics of Psychology Research Related to Famous Experiments

There have been many fascinating and groundbreaking experiments throughout the history of psychology, providing ample material for students looking for an interesting term paper topic. In your paper, you might choose to summarize the experiment, analyze the ethics of the research, or evaluate the implications of the study. Possible experiments that you might consider include:

  • The Milgram Obedience Experiment
  • The Stanford Prison Experiment
  • The Little Albert Experiment
  • Pavlov's Conditioning Experiments
  • The Asch Conformity Experiment
  • Harlow's Rhesus Monkey Experiments

Topics of Psychology Research About Historical Figures

One of the simplest ways to find a great topic is to choose an interesting person in the  history of psychology  and write a paper about them. Your paper might focus on many different elements of the individual's life, such as their biography, professional history, theories, or influence on psychology.

While this type of paper may be historical in nature, there is no need for this assignment to be dry or boring. Psychology is full of fascinating figures rife with intriguing stories and anecdotes. Consider such famous individuals as Sigmund Freud, B.F. Skinner, Harry Harlow, or one of the many other  eminent psychologists .

Psychology Research Topics About a Specific Career

​Another possible topic, depending on the course in which you are enrolled, is to write about specific career paths within the  field of psychology . This type of paper is especially appropriate if you are exploring different subtopics or considering which area interests you the most.

In your paper, you might opt to explore the typical duties of a psychologist, how much people working in these fields typically earn, and the different employment options that are available.

Topics of Psychology Research Involving Case Studies

One potentially interesting idea is to write a  psychology case study  of a particular individual or group of people. In this type of paper, you will provide an in-depth analysis of your subject, including a thorough biography.

Generally, you will also assess the person, often using a major psychological theory such as  Piaget's stages of cognitive development  or  Erikson's eight-stage theory of human development . It is also important to note that your paper doesn't necessarily have to be about someone you know personally.

In fact, many professors encourage students to write case studies on historical figures or fictional characters from books, television programs, or films.

Psychology Research Topics Involving Literature Reviews

Another possibility that would work well for a number of psychology courses is to do a literature review of a specific topic within psychology. A literature review involves finding a variety of sources on a particular subject, then summarizing and reporting on what these sources have to say about the topic.

Literature reviews are generally found in the  introduction  of journal articles and other  psychology papers , but this type of analysis also works well for a full-scale psychology term paper.

Topics of Psychology Research Based on Your Own Study or Experiment

Many psychology courses require students to design an actual psychological study or perform some type of experiment. In some cases, students simply devise the study and then imagine the possible results that might occur. In other situations, you may actually have the opportunity to collect data, analyze your findings, and write up your results.

Finding a topic for your study can be difficult, but there are plenty of great ways to come up with intriguing ideas. Start by considering your own interests as well as subjects you have studied in the past.

Online sources, newspaper articles, books , journal articles, and even your own class textbook are all great places to start searching for topics for your experiments and psychology term papers. Before you begin, learn more about  how to conduct a psychology experiment .

What This Means For You

After looking at this brief list of possible topics for psychology papers, it is easy to see that psychology is a very broad and diverse subject. While this variety makes it possible to find a topic that really catches your interest, it can sometimes make it very difficult for some students to select a good topic.

If you are still stumped by your assignment, ask your instructor for suggestions and consider a few from this list for inspiration.

  • Hockenbury, SE & Nolan, SA. Psychology. New York: Worth Publishers; 2014.
  • Santrock, JW. A Topical Approach to Lifespan Development. New York: McGraw-Hill Education; 2016.

By Kendra Cherry, MSEd Kendra Cherry, MS, is a psychosocial rehabilitation specialist, psychology educator, and author of the "Everything Psychology Book."

Grad Coach

Research Topics & Ideas: Psychology

100+ Psychology Topic Ideas To Fast-Track Your Research

Research topics and ideas in psychology

If you’re starting out on the dissertation or thesis journey for your psychology degree, the very first challenge you’ll face is finding a solid research topic . In this post, we’ll help get the topic ideation process started by providing a meaty list of research ideas, spanning a range of psychology sub-disciplines. We’ll also look at some examples from actual theses and dissertations to give you an idea of what these look like in the real world.

NB – This is just the start…

The topic ideation and evaluation process has multiple steps (which we’ll explain a little later). Therefore, it’s important to recognise that this post is only the first step in finding a high-quality psychology-centred research topic. To develop a research topic, you’ll need to identify a clear and convincing research gap , and a viable plan of action to fill that gap.

If this all sounds a bit intimidating, be sure to check out our free dissertation mini-course , which covers the process of writing a dissertation or thesis from A-Z. You can also sign up for our free webinar that explores how to find a high-quality research topic. Alternatively, if you’d like hands-on help, have a look at our 1-on-1 coaching service .

Overview: Psychology-Related Topics

  • How to find a research topic (video)
  • Behavioural psychology
  • Clinical psychology
  • Cognitive psychology
  • Developmental psychology
  • Educational psychology
  • Forensic psychology
  • Social psychology
  • Sports psychology
  • Examples of actual dissertation topics
  • Free Webinar : Topic Ideation 101
  • Where to get extra help

How To Find A Research Topic

In the video below, we explain how to find suitable research ideas (in psychology or any field), and how to then refine those into well-articulated potential topics for your dissertation or thesis. We also discuss a few important evaluation criteria to help you make the right choice for your project.

Below you’ll find a list of research ideas to get your thinking started. Please note that these research topic ideas are intentionally broad and generic, so you will need to refine them a fair deal using the techniques we discussed in the video above.

We’ve grouped the topic ideas based on a few popular areas of psychology to make it a little easier for you to find something in your particular field of interest. That said, there is naturally some overlap between topics, so keep this in mind.

Research Ideas: Behavioural Psychology

  • Cultural variation in behaviour and mental health of adolescents during a disaster: a case study
  • The impact of parental drug use and risky behaviour on early child development
  • The effects of video game violence on aggressive behaviour among teenage boys in school
  • The relationship between adverse childhood experiences and adult risk-seeking behaviour
  • The impact of physical exercise on anxiety and health-harming behaviour
  • The relationship between personality traits and addiction behaviour
  • The effects of reinforcement schedules on decision-making and associative learning
  • The effects of daily mindfulness practice on stress and anxiety in middle-aged women
  • The use of behavioural interventions in the treatment of eating disorders in poorer communities
  • Understanding implicit cognitive processes involved in the over-consumption of fast food
  • The use of cognitive behavioural therapy for alcohol addiction treatment
  • The impact of extensive technology use in children on long-term attention and focus
  • The impact of social media on self-destructive behaviour and poor mental health outcomes
  • Exploring the role of sleep and sleep deprivation on healthy behaviours

Research topic idea mega list

Research Ideas: Clinical Psychology

  • The use of mindfulness-based approaches in the treatment of anxiety disorders among college students
  • The use of technology in the delivery of psychological services in war-torn countries
  • The effectiveness of dialectical behaviour therapy for borderline personality disorder
  • The use of virtual reality technology in the treatment of phobias and PTSD among war veterans
  • The role of childhood adversity on adult mental health in immigrant populations in the USA
  • The role of genetics and epigenetics in the development of bipolar disorder in Pakistani women: an integrative review
  • The effectiveness of pharmacotherapy in the treatment of social anxiety among hikikomori in Japan
  • The perception of healthcare workers and patients on the use of teletherapy for the delivery of psychological services
  • The impact of social support on mental health outcomes among single parents.
  • The effectiveness of integrative therapeutic approaches in the treatment of schizophrenia
  • The effectiveness of trauma-focused therapies on post-traumatic growth in domestic abuse survivors
  • The role and use of cognitive-behavioural therapy for depression among first-generation students
  • The effectiveness of family therapy in addressing childhood trauma and depression
  • The impact of cultural mistrust on the diagnosis and treatment of mental health issues in culturally-diverse populations
  • The effectiveness of group therapy on post-traumatic stress symptoms among survivors of sexual assault

Research Topic Kickstarter - Need Help Finding A Research Topic?

Research Ideas: Cognitive Psychology

  • The impact of lifelong aerobic exercise on cognitive function in old age
  • The effects of evening screen use on cognitive development in preschool children
  • The impact of sleep deprivation on decision-making among graduate students
  • The use of neuroimaging to understand the neural basis of memory retrieval
  • The effect of conservative religious homes on social functioning in LGBT+ adolescents
  • The role of positive emotions in working memory among high school learners
  • The neural basis of decision-making and problem-solving during undergraduate statistic assessments
  • The neural basis of language processing among adults learning English as a second language
  • The role of technological tools in improving working memory in older adults
  • The role of attention in emotional face processing among adult males
  • The impact of depression on cognitive function during ageing The impact of daily meditation and mindfulness practice on cognitive function
  • The relationship between increased protein intake and improved cognitive function
  • The effects of stress on cognitive function among final-year learners

Research topic evaluator

Research Ideas: Developmental Psychology

  • The impact of maternal affection on cognitive, social, and emotional development
  • The effects of parenting styles on children’s executive function
  • The impact of late-night screen use on child development
  • The role of digital play on child development outcomes
  • Exploring the impact of poverty on early child development in Brazil
  • The trauma-informed care as moderating the impact of trauma on child development
  • Evaluating the relationship between peer relationship quality and child social development
  • The impact of child-targeted media and advertising on child behavioural development
  • The role of parental attachment in child resilience
  • The moderating impact of culture on bullying and child social development
  • The impact of single-parenting on child development in India
  • The impact of early educational interventions on child socio-emotional development
  • The impact of digital technology use on adolescent development and mental health
  • The impact of socioeconomic status on child executive function
  • The role of genetics and epigenetics on child neurodevelopmental outcomes linked to depression

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new topics for psychology research

Research Ideas: Educational Psychology

  • The relationship between self-regulated learning and academic performance in asynchronous versus synchronous learning environments
  • Exploring effective parental involvement strategies and their impact on student achievement
  • The role of intrinsic motivation in formative assessment in the classroom
  • The impact of classroom management and practice on student learning and behaviour
  • University students’ preference regarding online learning environments
  • The effects of gentrification on student achievement in traditionally poor neighbourhoods
  • The impact of teacher expectations and academic self-concept on K12 student mathematics performance
  • The use and effectiveness of game-based learning in a high school biology classroom
  • The impact of prejudice on the relationship between student motivation and academic performance among Black university students
  • The impact of culture on second language English student learning preferences
  • The effects of student self-efficacy and engagement on academic performance in secondary school mathematics
  • The role of metacognition in learning musicality in hip hop
  • The role of small group instruction on teacher efficacy and stress in early childhood education
  • The perception and use of multimedia among high school biology teachers in France
  • The use of augmented reality applications and its impact on student learning, motivation and attitude

Research Ideas: Forensic Psychology

  • The impact of trauma on the psychological functioning of police officers and first responders
  • Understanding cultural considerations during forensic psychological assessment and treatment of trauma
  • Ethical considerations of the use of AI in forensic psychology in the legal system
  • The psychological factors related to recidivism among white collar female offenders in the USA
  • The psychological factors related to false confessions among juveniles
  • Understanding the use of psychological assessment in the evaluation of eyewitness testimony in criminal courts in England
  • The impact of trauma on the reflective functioning of adult female sexual assault victims
  • The use and effectiveness of psychological interventions in reducing recidivism among non-violent criminals
  • The impact of domestic violence on the mental health and forensic evaluation of men
  • Exploring the ethical considerations and use of behavioural analysis in the study of criminal behaviour
  • The use and limitations of neuropsychological assessment in forensic evaluations
  • The use of social media forensics in evaluating criminal behaviour in violent crimes
  • The racialised use of psychological assessment in the evaluation of competency to stand trial in Canada
  • Exploring the use and availability of virtual reality technologies in forensic psychology in Spain
  • The impact of motivational interviewing-based interventions among criminalized drug users

Research Ideas: Social Psychology

  • The impact of prejudice and discrimination on social behaviour among African immigrants in South Africa
  • The impact of social networks on behaviour and well-being among young adult females
  • The effects of social identity on non-conformity in University students
  • The effects of group dynamics on risk-seeking behaviour in adult men
  • The impact of social media on the quality of interpersonal relationships among high school learners
  • The impact of parental emotional intelligence on pro-social behaviour in children and adolescents
  • The effects of conformity and deviance on social attitudes and behaviour during a global recession
  • The effects of Tik Tok on social comparison and self-esteem among teenage girls
  • Understanding gendered differences in social influence and algorithms on impulsive decision-making
  • The effects of social support on mental health among healthcare workers in the UK
  • The effects of gender roles on social behaviour among trans teens
  • The impact of perceived power and social status on the behaviour of social media influencers
  • The impact of social norms on prosocial behaviour among women
  • The effects of community participation on aggression and violence in middle-aged men
  • The impact of culture and gender on social behaviour during the COVID-19 pandemic

Research Ideas: Sports Psychology

  • The moderating role of cultural factors on the relationship between mental health and sports performance in team sports
  • The role of mindfulness practice in addressing stress and anxiety in young national athletes
  • The relationship between team cohesion and performance in cricket teams
  • The effect of transformational leadership on female sports teams in Canada
  • The effect of positive self-talk on athletic performance and motivation among Olympic athletes
  • The use and perception of hypnosis in New Zealand team sports Understanding stress and burnout in University team athletes
  • The efficacy of personalised nutrition and diet on athletic performance among sprinters
  • Exploring mental preparation techniques and their effect on athletic motivation and resilience among team-sport athletes
  • Exploring the perception and understanding of goal-setting characteristics on athletic performance among team coaches
  • The effects of motivational feedback on the performance of female gymnasts
  • The perception and use of visualization and imagery among coaches as a means to enhance sport performance
  • The impact of sports injuries on mental health and recovery in high school athletes
  • The moderating role of sleep on mental toughness and sports performance in Olympic athletes
  • The use and perception of technology in sports training and performance in little league softball

Free Webinar: How To Find A Dissertation Research Topic

Psychology-Related Dissertations & Theses

While the ideas we’ve presented above are a decent starting point for finding a research topic in psychology, they are fairly generic and non-specific. So, it helps to look at actual dissertations and theses to see how this all comes together in practice.

Below, we’ve included a selection of research projects from various psychology degree programs to help refine your thinking. These are actual dissertations and theses, written as part of Master’s and PhD-level programs, so they can provide some useful insight as to what a research topic looks like in practice.

  • Effects of a Patient Question Prompt List on Outpatient Palliative Care Appointments (McDarby, 2022)
  • The role of affect and exercise goals in physical activity engagement in younger and older adults (Stojanovic, 2022)
  • Lay Theories about Whether Emotion Helps or Hinders Reasoning and Well-being (Karnaze, 2022)
  • The effects of blast-induced traumatic brain injury on two transgenic models of Alzheimer’s Disease (Gann, 2020)
  • Understanding the parental mind: Examining the stability of parental reflective functioning across the birth of a child and associations with maternal mind-mindedness (Pitzen, 2021)
  • An investigation of ineffective ally behaviours (Collier, 2019)
  • Response Inhibition-Related Beta Power: Distinguishing Cognitively Intact Elders by Risk for Alzheimer’s Disease (Evans, 2021)
  • Recognition Memory of Extremely High-Frequency Words (Miller, 2019)
  • The Relationship between Dementia Caregiver Burden and Caregiver Communications in a Memory Clinic Setting (Martin, 2021)
  • Examination of Maternal Versus Paternal Ratings of Child Pre-Injury Functioning in Predicting Child Post-Traumatic Stress Symptoms (Sayer, 2021)
  • Electromyography As A Means of Predicting The Rubber Hand Illusion (Teaford, 2021)
  • Linking Diversity Climate and Feedback Seeking Through Interpersonal Processes and Race Effects (Flores, 2021)

Looking at these titles, you can probably pick up that the research topics here are far more specific and narrowly-focused , compared to the generic ones presented earlier. This is an important thing to keep in mind as you develop your own research topic. That is to say, to create a top-notch research topic, you must be precise and target a specific context with specific variables of interest . In other words, you need to identify a clear, well-justified research gap.

Fast-Track Your Topic Ideation

Still unsure about how to find the right topic for your research project? Check out our private coaching services , where we work with psychology students on a 1:1 basis to help them find the perfect topic.

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Topic Kickstarter: Research topics in education

10 Comments

Mariam Nakamanya

Great insight

Tom Byaruhanga

A very interesting site that offers a variety of options regarding research topics.

Derek Jansen

You’re most welcome

Aiman Kanwal

A good platform to get information

Chiemerie Lucy Okolo

Amazing and interesting options 👌

Mahwish Haris Awan

Very useful but had not any field of research in health psychology

Aishah

I feel honored going through this lovely stuff put together. Thank you so much

Olaniyan Olatunbosun

I need counseling psychology research topics

Fiso Ncube

very empowering and insightful presentations. Can I be assisted in crafting a school psychology-related research topic about African context

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Research Topics is a collection of previously published articles, features, and news stories. They are meant to serve as an information clearinghouse and represent some of APS’s most requested and publicly relevant subjects. Note: this content may reflect the accepted style and terminology of the date the articles were first published.

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Researchers explore how practices associated with mindfulness and meditation can affect decision-making and other cognitive processes.

new topics for psychology research

Mindfulness and Meditation

Psychological scientists are identifying cognitive, developmental, and cultural aspects of music perception and the essential role that music plays in our everyday lives.

A-440 Tuning Fork and Sheet Music

How does misinformation spread and how do we combat it? Psychological science sheds light on the mechanisms underlying misinformation and 'fake news.'

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Scientists are increasingly busting some myths and making new discoveries about a dark personality trait.

new topics for psychology research

Deal making at the international, business, and interpersonal levels involves a variety of emotional, social, and language factors that lead to a final agreement -- or a stalemate.

new topics for psychology research

Negotiation

Read about the wealth of psychological studies on neurodiversity and the differences in learning, attention, and mood.

new topics for psychology research

Neurodivergence

Psychological scientists are devoting an increasing amount of their research time examining the role of the brain in human behavior, emotion, and cognitive health.

new topics for psychology research

Neuroscience

Recent news events have sparked a surge of interest in the Dunning-Kruger effect -- a distorted view of one's knowledge and ability. Learn how this cognitive bias can spark overconfidence among world leaders and corporate giants.

new topics for psychology research

Overconfidence

Amid the epidemic of opioid addiction, psychological science has demonstrated that pain relief doesn't have to be pharmaceutical.

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Pain Management

Personality tests are the center of countless psychological studies exploring targeted marketing, workplace dynamics, and different brain structures.

new topics for psychology research

Personality Traits

Public trust in the police has remained flat for decades, a problem that has become especially salient due to recent events.

new topics for psychology research

Policing and Law Enforcement

A scientific analysis upends the notion that people on the political right are more biased about their ideological views than are people on the left.

new topics for psychology research

Political Differences

Why do we dawdle and delay, even on the most important tasks? Researchers explore the causes and consequences of procrastination.

Hourglass and calendar

Procrastination

Plenty of beliefs about human psychology are based on myth masquerading as facts. Psychological scientists have not only exposed the weak evidence for these notions, but can recommend strategies to help us to distinguish true science from bunk.

new topics for psychology research

Pseudoscience

Psychological researchers are examining the complexities of racism and xenophobia at both the interpersonal and societal levels.

new topics for psychology research

Racism and Discrimination

Psychological research explores how we evaluate, perceive, and choose whether to take risks.

new topics for psychology research

Why does self-control fail, and how can we boost it? Researchers explore the mechanisms underlying this important ability and how it develops over time.

This is an illustrations of many points on a path to the mountain top

Self-Control

The #metoo movement has brought sexual harassment to the center of public consciousness, raising questions about the causes of predatory actions. Psychological research shows how feeling powerful relates to sexually coercive behavior.

new topics for psychology research

Sexual Assault and Harassment

Insufficient sleep has been shown to have adverse effects at work, in driving, and even in court.

Student sleeping between piles of books

From the scent of flowers to the stench of hazardous chemicals, our sense of smell guides us through our environment and significantly influences our emotions, as scientists have discovered.

new topics for psychology research

How does athletic engagement and competition affect our thoughts and behaviors? Learn what psychological science has uncovered.

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New discoveries about the ill effects of psychological stress abound, but scientists are also learning about buffers to stress.

Knotted rope

Psychological scientists delve into study strategies, math anxiety, reading comprehension, and more.

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Studying and Learning

Research from APS on addiction and substance abuse.

new topics for psychology research

Substance Abuse and Addiction

Scientists show how get-aways and enjoyable activities affect our work lives and relationships.

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Taking a Break

Psychological research is fostering understanding of the important factors that contribute to effective teaching, from individual instruction to school climate.

new topics for psychology research

The psychological mechanisms that lead us to have faith in certain people and be suspicious of others are vast. Learn what psychological researchers have discovered about interpersonal trust.

new topics for psychology research

September 10 is World Suicide Prevention Day. Read about the steps that psychological scientists are taking to identify and help people at risk of taking their own lives.

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Understanding and Preventing Suicide

Psychological science suggests that behavioral 'nudges' which aim to alter individuals' actions rather than their attitudes are essential to promoting vaccination against COVID-19 and other vaccine-preventable diseases.

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Vaccination

The effects of playing video games on well-being seem to depend largely on why and how an individual chooses to partake.

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Video Games

The way the brain and the human eye process visual stimuli, including illusions, is a thriving area of psychological science.

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Researchers unravel the mystery of voting behavior, including why people vote in seemingly unpredictable or illogical ways.

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How does weather, both ordinary and extreme, affect decision-making, behavior, and emotions?

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Weather and Behavior

Research in psychological science reveals the causes and consequences of bullying behavior in the office.

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Workplace Bullying

When done well, efforts to improve intergroup harmony at work can uplift individuals and lead entire organizations to perform at a higher level.

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Workplace Diversity

Privacy overview.

new topics for psychology research

Research Topics

Cutting-edge research into the workings of the human mind

Our faculty conducts scientific research on topics that span across all areas of psychology. Some themes of research concentration are listed below. Click the topics to see the list of department faculty associated with each theme.

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Addictive Behaviors

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Computational Approaches

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Decision Science

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Developmental Approaches

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Interventions

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Learning & Memory

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Mathematical Cognition

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Meaning & Mental Representation

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Motivation & Emotion

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Neuroimaging

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Plasticity & Change

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Psychopathology & Risk

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Reasoning & Problem Solving

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Self & Identity

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Self-Regulation & Control

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Social Cognition

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Stereotyping & Stereotype Threat

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Vision Science

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Words & Categories

80 fascinating psychology research questions for your next project

Last updated

15 February 2024

Reviewed by

Brittany Ferri, PhD, OTR/L

Psychology research is essential for furthering our understanding of human behavior and improving the diagnosis and treatment of psychological conditions.

When psychologists know more about how different social and cultural factors influence how humans act, think, and feel, they can recommend improvements to practices in areas such as education, sport, healthcare, and law enforcement.

Below, you will find 80 research question examples across 16 branches of psychology. First, though, let’s look at some tips to help you select a suitable research topic.

  • How to choose a good psychology research topic

Psychology has many branches that break down further into topics. Choosing a topic for your psychology research paper can be daunting because there are so many to choose from. It’s an important choice, as the topic you select will open up a range of questions to explore.

The tips below can help you find a psychology research topic that suits your skills and interests.

Tip #1: Select a topic that interests you

Passion and interest should fuel every research project. A topic that fascinates you will most likely interest others as well. Think about the questions you and others might have and decide on the issues that matter most. Draw on your own interests, but also keep your research topical and relevant to others.

Don’t limit yourself to a topic that you already know about. Instead, choose one that will make you want to know more and dig deeper. This will keep you motivated and excited about your research.

Tip #2: Choose a topic with a manageable scope

If your topic is too broad, you can get overwhelmed by the amount of information available and have trouble maintaining focus. On the other hand, you may find it difficult to find enough information if you choose a topic that is too narrow.

To determine if the topic is too broad or too narrow, start researching as early as possible. If you find there’s an overwhelming amount of research material, you’ll probably need to narrow the topic down. For example, instead of researching the general population, it might be easier to focus on a specific age group. Ask yourself what area of the general topic interests you most and focus on that.

If your scope is too narrow, try to generalize or focus on a larger related topic. Expand your search criteria or select additional databases for information. Consider if the topic is too new to have much information published on it as well.

Tip #3: Select a topic that will produce useful and relevant insights

Doing some preliminary research will reveal any existing research on the topic. If there is existing research, will you be able to produce new insights? You might need to focus on a different area or see if the existing research has limitations that you can overcome.

Bear in mind that finding new information from which to draw fresh insights may be impossible if your topic has been over-researched.

You’ll also need to consider whether your topic is relevant to current trends and needs. For example, researching psychology topics related to social media use may be highly relevant today.

  • 80 psychology research topics and questions

Psychology is a broad subject with many branches and potential areas of study. Here are some of them:

Developmental

Personality

Experimental

Organizational

Educational

Neuropsychology

Controversial topics

Below we offer some suggestions on research topics and questions that can get you started. Keep in mind that these are not all-inclusive but should be personalized to fit the theme of your paper.

Social psychology research topics and questions

Social psychology has roots as far back as the 18th century. In simple terms, it’s the study of how behavior is influenced by the presence and behavior of others. It is the science of finding out who we are, who we think we are, and how our perceptions affect ourselves and others. It looks at personalities, relationships, and group behavior.

Here are some potential research questions and paper titles for this topic:

How does social media use impact perceptions of body image in male adolescents?

2. Is childhood bullying a risk factor for social anxiety in adults?

Is homophobia in individuals caused by genetic or environmental factors?

What is the most important psychological predictor of a person’s willingness to donate to charity?

Does a person’s height impact how other people perceive them? If so, how?

Cognitive psychology research questions

Cognitive psychology is the branch that focuses on the interactions of thinking, emotion, creativity, and problem-solving. It also explores the reasons humans think the way they do.

This topic involves exploring how people think by measuring intelligence, thoughts, and cognition. 

Here are some research question ideas:

6. Is there a link between chronic stress and memory function?

7. Can certain kinds of music trigger memories in people with memory loss?

8. Do remote meetings impact the efficacy of team decision-making?

9. Do word games and puzzles slow cognitive decline in adults over the age of 80?

10. Does watching television impact a child’s reading ability?

Developmental psychology research questions

Developmental psychology is the study of how humans grow and change over their lifespan. It usually focuses on the social, emotional, and physical development of babies and children, though it can apply to people of all ages. Developmental psychology is important for understanding how we learn, mature, and adapt to changes.

Here are some questions that might inspire your research:

11. Does grief accelerate the aging process?

12. How do parent–child attachment patterns influence the development of emotion regulation in teenagers?

13. Does bilingualism affect cognitive decline in adults over the age of 70?

14. How does the transition to adulthood impact decision-making abilities

15. How does early exposure to music impact mental health and well-being in school-aged children?

Personality psychology research questions

Personality psychology studies personalities, how they develop, their structures, and the processes that define them. It looks at intelligence, disposition, moral beliefs, thoughts, and reactions.

The goal of this branch of psychology is to scientifically interpret the way personality patterns manifest into an individual’s behaviors. Here are some example research questions:

16. Nature vs. nurture: Which impacts personality development the most?

17. The role of genetics on personality: Does an adopted child take on their biological parents’ personality traits?

18. How do personality traits influence leadership styles and effectiveness in organizational settings?

19. Is there a relationship between an individual’s personality and mental health?

20. Can a chronic illness affect your personality?

Abnormal psychology research questions

As the name suggests, abnormal psychology is a branch that focuses on abnormal behavior and psychopathology (the scientific study of mental illness or disorders).

Abnormal behavior can be challenging to define. Who decides what is “normal”? As such, psychologists in this area focus on the level of distress that certain behaviors may cause, although this typically involves studying mental health conditions such as depression, obsessive-compulsive disorder (OCD), and phobias.

Here are some questions to consider:

21. How does technology impact the development of social anxiety disorder?

22. What are the factors behind the rising incidence of eating disorders in adolescents?

23. Are mindfulness-based interventions effective in the treatment of PTSD?

24. Is there a connection between depression and gambling addiction?

25. Can physical trauma cause psychopathy?

Clinical psychology research questions

Clinical psychology deals with assessing and treating mental illness or abnormal or psychiatric behaviors. It differs from abnormal psychology in that it focuses more on treatments and clinical aspects, while abnormal psychology is more behavioral focused.

This is a specialty area that provides care and treatment for complex mental health conditions. This can include treatment, not only for individuals but for couples, families, and other groups. Clinical psychology also supports communities, conducts research, and offers training to promote mental health. This category is very broad, so there are lots of topics to explore.

Below are some example research questions to consider:

26. Do criminals require more specific therapies or interventions?

27. How effective are selective serotonin reuptake inhibitors in treating mental health disorders?

28. Are there any disadvantages to humanistic therapy?

29. Can group therapy be more beneficial than one-on-one therapy sessions?

30. What are the factors to consider when selecting the right treatment plan for patients with anxiety?

Experimental psychology research questions

Experimental psychology deals with studies that can prove or disprove a hypothesis. Psychologists in this field use scientific methods to collect data on basic psychological processes such as memory, cognition, and learning. They use this data to test the whys and hows of behavior and how outside factors influence its creation.

Areas of interest in this branch relate to perception, memory, emotion, and sensation. The below are example questions that could inspire your own research:

31. Do male or female parents/carers have a more calming influence on children?

32. Will your preference for a genre of music increase the more you listen to it?

33. What are the psychological effects of posting on social media vs. not posting?

34. How is productivity affected by social connection?

35. Is cheating contagious?

Organizational psychology research questions

Organizational psychology studies human behavior in the workplace. It is most frequently used to evaluate an employee, group, or a company’s organizational dynamics. Researchers aim to isolate issues and identify solutions.

This area of study can be beneficial to both employees and employers since the goal is to improve the overall work environment and experience. Researchers apply psychological principles and findings to recommend improvements in performance, communication, job satisfaction, and safety. 

Some potential research questions include the following:

36. How do different leadership styles affect employee morale?

37. Do longer lunch breaks boost employee productivity?

38. Is gender an antecedent to workplace stress?

39. What is the most effective way to promote work–life balance among employees?

40. How do different organizational structures impact the effectiveness of communication, decision-making, and productivity?

Forensic psychology research questions

Some questions to consider exploring in this branch of psychology are:

41. How does incarceration affect mental health?

42. Is childhood trauma a driver for criminal behavior during adulthood?

43. Are people with mental health conditions more likely to be victims of crimes?

44. What are the drivers of false memories, and how do they impact the justice system?

45. Is the media responsible for copycat crimes?

Educational psychology research questions

Educational psychology studies children in an educational setting. It covers topics like teaching methods, aptitude assessment, self-motivation, technology, and parental involvement.

Research in this field of psychology is vital for understanding and optimizing learning processes. It informs educators about cognitive development, learning styles, and effective teaching strategies.

Here are some example research questions:

46. Are different teaching styles more beneficial for children at different times of the day?

47. Can listening to classical music regularly increase a student’s test scores?

48. Is there a connection between sugar consumption and knowledge retention in students?

49. Does sleep duration and quality impact academic performance?

50. Does daily meditation at school influence students’ academic performance and mental health?

Sports psychology research question examples

Sport psychology aims to optimize physical performance and well-being in athletes by using cognitive and behavioral practices and interventions. Some methods include counseling, training, and clinical interventions.

Research in this area is important because it can improve team and individual performance, resilience, motivation, confidence, and overall well-being

Here are some research question ideas for you to consider:

51. How can a famous coach affect a team’s performance?

52. How can athletes control negative emotions in violent or high-contact sports?

53. How does using social media impact an athlete’s performance and well-being?

54. Can psychological interventions help with injury rehabilitation?

55. How can mindfulness practices boost sports performance?

Cultural psychology research question examples

The premise of this branch of psychology is that mind and culture are inseparable. In other words, people are shaped by their cultures, and their cultures are shaped by them. This can be a complex interaction.

Cultural psychology is vital as it explores how cultural context shapes individuals’ thoughts, behaviors, and perceptions. It provides insights into diverse perspectives, promoting cross-cultural understanding and reducing biases.

Here are some ideas that you might consider researching:

56. Are there cultural differences in how people perceive and deal with pain?

57. Are different cultures at increased risk of developing mental health conditions?

58. Are there cultural differences in coping strategies for stress?

59. Do our different cultures shape our personalities?

60. How does multi-generational culture influence family values and structure?

Health psychology research question examples

Health psychology is a crucial field of study. Understanding how psychological factors influence health behaviors, adherence to medical treatments, and overall wellness enables health experts to develop effective interventions and preventive measures, ultimately improving health outcomes.

Health psychology also aids in managing stress, promoting healthy behaviors, and optimizing mental health, fostering a holistic approach to well-being.

Here are five ideas to inspire research in this field:

61. How can health psychology interventions improve lifestyle behaviors to prevent cardiovascular diseases?

62. What role do social norms play in vaping among adolescents?

63. What role do personality traits play in the development and management of chronic pain conditions?

64. How do cultural beliefs and attitudes influence health-seeking behaviors in diverse populations?

65. What are the psychological factors influencing the adherence to preventive health behaviors, such as vaccination and regular screenings?

Neuropsychology research paper question examples

Neuropsychology research explores how a person’s cognition and behavior are related to their brain and nervous system. Researchers aim to advance the diagnosis and treatment of behavioral and cognitive effects of neurological disorders.

Researchers may work with children facing learning or developmental challenges, or with adults with declining cognitive abilities. They may also focus on injuries or illnesses of the brain, such as traumatic brain injuries, to determine the effect on cognitive and behavioral functions.

Neuropsychology informs diagnosis and treatment strategies for conditions such as dementia, traumatic brain injuries, and psychiatric disorders. Understanding the neural basis of behavior enhances our ability to optimize cognitive functioning, rehabilitate people with brain injuries, and improve patient care.

Here are some example research questions to consider:

66. How do neurotransmitter imbalances in specific brain regions contribute to mood disorders such as depression?

67. How can a traumatic brain injury affect memory?

68. What neural processes underlie attention deficits in people with ADHD?

69. Do medications affect the brain differently after a traumatic brain injury?

70. What are the behavioral effects of prolonged brain swelling?

Psychology of religion research question examples

The psychology of religion is a field that studies the interplay between belief systems, spirituality, and mental well-being. It explores the application of the psychological methods and interpretive frameworks of religious traditions and how they relate to both religious and non-religious people.

Psychology of religion research contributes to a holistic understanding of human experiences. It fosters cultural competence and guides therapeutic approaches that respect diverse spiritual beliefs.

Here are some example research questions in this field:

71. What impact does a religious upbringing have on a child’s self-esteem?

72. How do religious beliefs shape decision-making and perceptions of morality?

73. What is the impact of religious indoctrination?

74. Is there correlation between religious and mindfulness practices?

75. How does religious affiliation impact attitudes towards mental health treatment and help-seeking behaviors?

Controversial topics in psychology research question examples

Some psychology topics don’t fit into any of the subcategories above, but they may still be worthwhile topics to consider. These topics are the ones that spark interest, conversation, debate, and disagreement. They are often inspired by current issues and assess the validity of older research.

Consider some of these research question examples:

76. How does the rise in on-screen violence impact behavior in adolescents.

77. Should access to social media platforms be restricted in children under the age of 12 to improve mental health?

78. Are prescription mental health medications over-prescribed in older adults? If so, what are the effects of this?

79. Cognitive biases in AI: what are the implications for decision-making?

80. What are the psychological and ethical implications of using virtual reality in exposure therapy for treating trauma-related conditions?

  • Inspiration for your next psychology research project

You can choose from a diverse range of research questions that intersect and overlap across various specialties.

From cognitive psychology to clinical studies, each inquiry contributes to a deeper understanding of the human mind and behavior. Importantly, the relevance of these questions transcends individual disciplines, as many findings offer insights applicable across multiple areas of study.

As health trends evolve and societal needs shift, new topics emerge, fueling continual exploration and discovery. Diving into this ever-changing and expanding area of study enables you to navigate the complexities of the human experience and pave the way for innovative solutions to the challenges of tomorrow.

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Psychology Research Topics – Ideas for Your Paper

new topics for psychology research

While it may seem that a research paper requires a creative approach, in fact, it is focused on scientific writing more. Students need to conduct research to fill in their literature review part and to create a methodology section. Additionally, students need to use theoretical concepts and research methods to create a research paper in psychology successfully. 

However, before proceeding to the content part students need to choose a topic. While choosing a topic may seem the easiest step in writing a psychology research paper, in fact, it is not true. Students often struggle to make decisions among a wide variety of topics and subfields. If you are in the same trouble now you can use the useful list provided by the Dissertation Team “ 200+ Psychology Research Topics for Your Paper ” which is the website that can also write a research paper or dissertation in psychology for you.

How to Choose Psychology Research Topics

new topics for psychology research

The most important criterion for choosing a topic is that it should be relevant to the psychology field. To make sure that the topic is relevant you need to conduct preliminary research. It implies the following: 

  • Reviewing current trends in psychology and popular research studies 
  • Finding the information in the material provided by your professor 
  • Scrolling the internet to find current non-solved issues in psychology 
  • This way you will be able to learn what topics are relevant and would be highly appreciated by your professor.

Additionally, you should remember that you would necessarily need to wait until your professor approves that topic. You need to submit your research question to the professor and ask whether they consider it relevant and allow you to use it for your research paper.

Get Ready to Choose Psychology Topics to Research

You should realize that the difficulty of writing a research paper directly depends on the availability of the literature on this topic. You simply would not be able to write a psychology research paper if the topic of your choice had not been investigated by anyone before. When writing a research paper the students should necessarily create a literature review. You can learn more about what is a literature review and how to write it here . 

Importance of Literature Review 

In your literature review, you would need to gather the relevant studies that have been conducted regarding that topic. You would need to use the findings of the authors who conducted the research and tell how effective their research was on the topic. You would necessarily need this information to investigate the topic further. There are two options for how you can use the research of other authors for your research paper: 

  • You can highlight the existing gaps in the literature as research regarding the specific topic and outline the ways your research paper will fill them. 
  • You can contribute your research to those that exist in findings and make the research issue even more understandable for the scientific society.

Therefore, you need to make sure that there is enough literature in online or real libraries. 

Conduct a Pre-Research for Psychology Research Paper Topics

As we have already mentioned you should necessarily be sure that there is enough literature for you to conduct a literature review and use it for your research paper. Therefore, we will provide you with useful advice on how to conduct literature research to make sure that this topic will be easy for you to develop.

  • Choose a library: Firstly you need to choose an online library that you would use to research the available literature. You can simply use Google Scholar which combines scholarly articles, books and other sources of information. This would allow you to quickly review all the available literature. 
  • Enter keywords: to conduct research effectively you need to use the keywords which are relevant to your research question. For example, if your research question is “how the use of the Internet affects the development of children”, you should answer such keywords as “Internet and children development”, “How the Internet affects children’s development”, “Effect of the Internet on development and brain”
  • Use filters: usually, the professors request to use the relevant and new literature sources. Therefore you need to outline the minimum year of publication for the sources. For example, if your professor has asked you to use the sources which have been published no more than 10 years ago you should put a filter of minimum 2014 year. This way you would be able to see all the relevant sources. Otherwise, you will need to sort tons of literature that could have been published 30 or even 40 years ago. 
  • Review the number of sources: after the filters have been applied and the keywords have been entered you need to see how many results the search engine provides. If you see that there are at least five relevant literature sources such as research articles or books you can understand that this topic has been widely researched and you can use it. 

You can start saving the relevant sources which you have found during your pre-research.

Help with Social Psychology Research Topics

new topics for psychology research

As we have mentioned, choosing a psychology topic may not be that easy. They should be relevant and will guide you throughout all the research paper writing and you will be relying on it. Everything that you will research will be based on the research question and hypothesis of your research question. However, if you do not want to trouble yourself with all of these challenges you can simply visit Dissertation Team or any other website and order quick research paper help.

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By Andy Sowards

Im a professional Freelancer specializing in Web Developer, Design, Programming web applications. Im an Avid member of the Design/Development community and a Serial Blogger. follow me on Twitter @AndySowards

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April 23, 2024

Research in Context: Treating depression

Finding better approaches.

While effective treatments for major depression are available, there is still room for improvement. This special Research in Context feature explores the development of more effective ways to treat depression, including personalized treatment approaches and both old and new drugs.

Woman standing on a road between a bleak, desolate area and a lush, green area.

Everyone has a bad day sometimes. People experience various types of stress in the course of everyday life. These stressors can cause sadness, anxiety, hopelessness, frustration, or guilt. You may not enjoy the activities you usually do. These feelings tend to be only temporary. Once circumstances change, and the source of stress goes away, your mood usually improves. But sometimes, these feelings don’t go away. When these feelings stick around for at least two weeks and interfere with your daily activities, it’s called major depression, or clinical depression.

In 2021, 8.3% of U.S. adults experienced major depression. That’s about 21 million people. Among adolescents, the prevalence was much greater—more than 20%. Major depression can bring decreased energy, difficulty thinking straight, sleep problems, loss of appetite, and even physical pain. People with major depression may become unable to meet their responsibilities at work or home. Depression can also lead people to use alcohol or drugs or engage in high-risk activities. In the most extreme cases, depression can drive people to self-harm or even suicide.

The good news is that effective treatments are available. But current treatments have limitations. That’s why NIH-funded researchers have been working to develop more effective ways to treat depression. These include finding ways to predict whether certain treatments will help a given patient. They're also trying to develop more effective drugs or, in some cases, find new uses for existing drugs.

Finding the right treatments

The most common treatments for depression include psychotherapy, medications, or a combination. Mild depression may be treated with psychotherapy. Moderate to severe depression often requires the addition of medication.

Several types of psychotherapy have been shown to help relieve depression symptoms. For example, cognitive behavioral therapy helps people to recognize harmful ways of thinking and teaches them how to change these. Some researchers are working to develop new therapies to enhance people’s positive emotions. But good psychotherapy can be hard to access due to the cost, scheduling difficulties, or lack of available providers. The recent growth of telehealth services for mental health has improved access in some cases.

There are many antidepressant drugs on the market. Different drugs will work best on different patients. But it can be challenging to predict which drugs will work for a given patient. And it can take anywhere from 6 to 12 weeks to know whether a drug is working. Finding an effective drug can involve a long period of trial and error, with no guarantee of results.

If depression doesn’t improve with psychotherapy or medications, brain stimulation therapies could be used. Electroconvulsive therapy, or ECT, uses electrodes to send electric current into the brain. A newer technique, transcranial magnetic stimulation (TMS), stimulates the brain using magnetic fields. These treatments must be administered by specially trained health professionals.

“A lot of patients, they kind of muddle along, treatment after treatment, with little idea whether something’s going to work,” says psychiatric researcher Dr. Amit Etkin.

One reason it’s difficult to know which antidepressant medications will work is that there are likely different biological mechanisms that can cause depression. Two people with similar symptoms may both be diagnosed with depression, but the causes of their symptoms could be different. As NIH depression researcher Dr. Carlos Zarate explains, “we believe that there’s not one depression, but hundreds of depressions.”

Depression may be due to many factors. Genetics can put certain people at risk for depression. Stressful situations, physical health conditions, and medications may contribute. And depression can also be part of a more complicated mental disorder, such as bipolar disorder. All of these can affect which treatment would be best to use.

Etkin has been developing methods to distinguish patients with different types of depression based on measurable biological features, or biomarkers. The idea is that different types of patients would respond differently to various treatments. Etkin calls this approach “precision psychiatry.”

One such type of biomarker is electrical activity in the brain. A technique called electroencephalography, or EEG, measures electrical activity using electrodes placed on the scalp. When Etkin was at Stanford University, he led a research team that developed a machine-learning algorithm to predict treatment response based on EEG signals. The team applied the algorithm to data from a clinical trial of the antidepressant sertraline (Zoloft) involving more than 300 people.

Young woman undergoing electroencephalography.

EEG data for the participants were collected at the outset. Participants were then randomly assigned to take either sertraline or an inactive placebo for eight weeks. The team found a specific set of signals that predicted the participants’ responses to sertraline. The same neural “signature” also predicted which patients with depression responded to medication in a separate group.

Etkin’s team also examined this neural signature in a set of patients who were treated with TMS and psychotherapy. People who were predicted to respond less to sertraline had a greater response to the TMS/psychotherapy combination.

Etkin continues to develop methods for personalized depression treatment through his company, Alto Neuroscience. He notes that EEG has the advantage of being low-cost and accessible; data can even be collected in a patient’s home. That’s important for being able to get personalized treatments to the large number of people they could help. He’s also working on developing antidepressant drugs targeted to specific EEG profiles. Candidate drugs are in clinical trials now.

“It’s not like a pie-in-the-sky future thing, 20-30 years from now,” Etkin explains. “This is something that could be in people's hands within the next five years.”

New tricks for old drugs

While some researchers focus on matching patients with their optimal treatments, others aim to find treatments that can work for many different patients. It turns out that some drugs we’ve known about for decades might be very effective antidepressants, but we didn’t recognize their antidepressant properties until recently.

One such drug is ketamine. Ketamine has been used as an anesthetic for more than 50 years. Around the turn of this century, researchers started to discover its potential as an antidepressant. Zarate and others have found that, unlike traditional antidepressants that can take weeks to take effect, ketamine can improve depression in as little as one day. And a single dose can have an effect for a week or more. In 2019, the FDA approved a form of ketamine for treating depression that is resistant to other treatments.

But ketamine has drawbacks of its own. It’s a dissociative drug, meaning that it can make people feel disconnected from their body and environment. It also has the potential for addiction and misuse. For these reasons, it’s a controlled substance and can only be administered in a doctor’s office or clinic.

Another class of drugs being studied as possible antidepressants are psychedelics. These include lysergic acid diethylamide (LSD) and psilocybin, the active ingredient in magic mushrooms. These drugs can temporarily alter a person’s mood, thoughts, and perceptions of reality. Some have historically been used for religious rituals, but they are also used recreationally.

In clinical studies, psychedelics are typically administered in combination with psychotherapy. This includes several preparatory sessions with a therapist in the weeks before getting the drug, and several sessions in the weeks following to help people process their experiences. The drugs are administered in a controlled setting.

Dr. Stephen Ross, co-director of the New York University Langone Health Center for Psychedelic Medicine, describes a typical session: “It takes place in a living room-like setting. The person is prepared, and they state their intention. They take the drug, they lie supine, they put on eye shades and preselected music, and two therapists monitor them.” Sessions last for as long as the acute effects of the drug last, which is typically several hours. This is a healthcare-intensive intervention given the time and personnel needed.

In 2016, Ross led a clinical trial examining whether psilocybin-assisted therapy could reduce depression and anxiety in people with cancer. According to Ross, as many as 40% of people with cancer have clinically significant anxiety and depression. The study showed that a single psilocybin session led to substantial reductions in anxiety and depression compared with a placebo. These reductions were evident as soon as one day after psilocybin administration. Six months later, 60-80% of participants still had reduced depression and anxiety.

Psychedelic drugs frequently trigger mystical experiences in the people who take them. “People can feel a sense…that their consciousness is part of a greater consciousness or that all energy is one,” Ross explains. “People can have an experience that for them feels more ‘real’ than regular reality. They can feel transported to a different dimension of reality.”

About three out of four participants in Ross’s study said it was among the most meaningful experiences of their lives. And the degree of mystical experience correlated with the drug’s therapeutic effect. A long-term follow-up study found that the effects of the treatment continued more than four years later.

If these results seem too good to be true, Ross is quick to point out that it was a small study, with only 29 participants, although similar studies from other groups have yielded similar results. Psychedelics haven’t yet been shown to be effective in a large, controlled clinical trial. Ross is now conducting a trial with 200 people to see if the results of his earlier study pan out in this larger group. For now, though, psychedelics remain experimental drugs—approved for testing, but not for routine medical use.

Unlike ketamine, psychedelics aren’t considered addictive. But they, too, carry risks, which certain conditions may increase. Psychedelics can cause cardiovascular complications. They can cause psychosis in people who are predisposed to it. In uncontrolled settings, they have the risk of causing anxiety, confusion, and paranoia—a so-called “bad trip”—that can lead the person taking the drug to harm themself or others. This is why psychedelic-assisted therapy takes place in such tightly controlled settings. That increases the cost and complexity of the therapy, which may prevent many people from having access to it.

Better, safer drugs

Despite the promise of ketamine or psychedelics, their drawbacks have led some researchers to look for drugs that work like them but with fewer side effects.

Depression is thought to be caused by the loss of connections between nerve cells, or neurons, in certain regions of the brain. Ketamine and psychedelics both promote the brain’s ability to repair these connections, a quality called plasticity. If we could understand how these drugs encourage plasticity, we might be able to design drugs that can do so without the side effects.

Neuron with 5-HT2A receptors inside.

Dr. David Olson at the University of California, Davis studies how psychedelics work at the cellular and molecular levels. The drugs appear to promote plasticity by binding to a receptor in cells called the 5-hydroxytryptamine 2A receptor (5-HT2AR). But many other compounds also bind 5-HT2AR without promoting plasticity. In a recent NIH-funded study, Olson showed that 5-HT2AR can be found both inside and on the surface of the cell. Only compounds that bound to the receptor inside the cells promoted plasticity. This suggests that a drug has to be able to get into the cell to promote plasticity.

Moreover, not all drugs that bind 5-HT2AR have psychedelic effects. Olson’s team has developed a molecular sensor, called psychLight, that can identify which compounds that bind 5-HT2AR have psychedelic effects. Using psychLight, they identified compounds that are not psychedelic but still have rapid and long-lasting antidepressant effects in animal models. He’s founded a company, Delix Therapeutics, to further develop drugs that promote plasticity.

Meanwhile, Zarate and his colleagues have been investigating a compound related to ketamine called hydroxynorketamine (HNK). Ketamine is converted to HNK in the body, and this process appears to be required for ketamine’s antidepressant effects. Administering HNK directly produced antidepressant-like effects in mice. At the same time, it did not cause the dissociative side effects and addiction caused by ketamine. Zarate’s team has already completed phase I trials of HNK in people showing that it’s safe. Phase II trials to find out whether it’s effective are scheduled to begin soon.  

“What [ketamine and psychedelics] are doing for the field is they’re helping us realize that it is possible to move toward a repair model versus a symptom mitigation model,” Olson says. Unlike existing antidepressants, which just relieve the symptoms of depression, these drugs appear to fix the underlying causes. That’s likely why they work faster and produce longer-lasting effects. This research is bringing us closer to having safer antidepressants that only need to be taken once in a while, instead of every day.

—by Brian Doctrow, Ph.D.

Related Links

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References:  An electroencephalographic signature predicts antidepressant response in major depression.  Wu W, Zhang Y, Jiang J, Lucas MV, Fonzo GA, Rolle CE, Cooper C, Chin-Fatt C, Krepel N, Cornelssen CA, Wright R, Toll RT, Trivedi HM, Monuszko K, Caudle TL, Sarhadi K, Jha MK, Trombello JM, Deckersbach T, Adams P, McGrath PJ, Weissman MM, Fava M, Pizzagalli DA, Arns M, Trivedi MH, Etkin A.  Nat Biotechnol.  2020 Feb 10. doi: 10.1038/s41587-019-0397-3. Epub 2020 Feb 10. PMID: 32042166. Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial. Ross S, Bossis A, Guss J, Agin-Liebes G, Malone T, Cohen B, Mennenga SE, Belser A, Kalliontzi K, Babb J, Su Z, Corby P, Schmidt BL. J Psychopharmacol . 2016 Dec;30(12):1165-1180. doi: 10.1177/0269881116675512. PMID: 27909164. Long-term follow-up of psilocybin-assisted psychotherapy for psychiatric and existential distress in patients with life-threatening cancer. Agin-Liebes GI, Malone T, Yalch MM, Mennenga SE, Ponté KL, Guss J, Bossis AP, Grigsby J, Fischer S, Ross S. J Psychopharmacol . 2020 Feb;34(2):155-166. doi: 10.1177/0269881119897615. Epub 2020 Jan 9. PMID: 31916890. Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors.  Vargas MV, Dunlap LE, Dong C, Carter SJ, Tombari RJ, Jami SA, Cameron LP, Patel SD, Hennessey JJ, Saeger HN, McCorvy JD, Gray JA, Tian L, Olson DE.  Science . 2023 Feb 17;379(6633):700-706. doi: 10.1126/science.adf0435. Epub 2023 Feb 16. PMID: 36795823. Psychedelic-inspired drug discovery using an engineered biosensor.  Dong C, Ly C, Dunlap LE, Vargas MV, Sun J, Hwang IW, Azinfar A, Oh WC, Wetsel WC, Olson DE, Tian L.  Cell . 2021 Apr 8: S0092-8674(21)00374-3. doi: 10.1016/j.cell.2021.03.043. Epub 2021 Apr 28. PMID: 33915107. NMDAR inhibition-independent antidepressant actions of ketamine metabolites. Zanos P, Moaddel R, Morris PJ, Georgiou P, Fischell J, Elmer GI, Alkondon M, Yuan P, Pribut HJ, Singh NS, Dossou KS, Fang Y, Huang XP, Mayo CL, Wainer IW, Albuquerque EX, Thompson SM, Thomas CJ, Zarate CA Jr, Gould TD. Nature . 2016 May 26;533(7604):481-6. doi: 10.1038/nature17998. Epub 2016 May 4. PMID: 27144355.

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How Pew Research Center will report on generations moving forward

Journalists, researchers and the public often look at society through the lens of generation, using terms like Millennial or Gen Z to describe groups of similarly aged people. This approach can help readers see themselves in the data and assess where we are and where we’re headed as a country.

Pew Research Center has been at the forefront of generational research over the years, telling the story of Millennials as they came of age politically and as they moved more firmly into adult life . In recent years, we’ve also been eager to learn about Gen Z as the leading edge of this generation moves into adulthood.

But generational research has become a crowded arena. The field has been flooded with content that’s often sold as research but is more like clickbait or marketing mythology. There’s also been a growing chorus of criticism about generational research and generational labels in particular.

Recently, as we were preparing to embark on a major research project related to Gen Z, we decided to take a step back and consider how we can study generations in a way that aligns with our values of accuracy, rigor and providing a foundation of facts that enriches the public dialogue.

A typical generation spans 15 to 18 years. As many critics of generational research point out, there is great diversity of thought, experience and behavior within generations.

We set out on a yearlong process of assessing the landscape of generational research. We spoke with experts from outside Pew Research Center, including those who have been publicly critical of our generational analysis, to get their take on the pros and cons of this type of work. We invested in methodological testing to determine whether we could compare findings from our earlier telephone surveys to the online ones we’re conducting now. And we experimented with higher-level statistical analyses that would allow us to isolate the effect of generation.

What emerged from this process was a set of clear guidelines that will help frame our approach going forward. Many of these are principles we’ve always adhered to , but others will require us to change the way we’ve been doing things in recent years.

Here’s a short overview of how we’ll approach generational research in the future:

We’ll only do generational analysis when we have historical data that allows us to compare generations at similar stages of life. When comparing generations, it’s crucial to control for age. In other words, researchers need to look at each generation or age cohort at a similar point in the life cycle. (“Age cohort” is a fancy way of referring to a group of people who were born around the same time.)

When doing this kind of research, the question isn’t whether young adults today are different from middle-aged or older adults today. The question is whether young adults today are different from young adults at some specific point in the past.

To answer this question, it’s necessary to have data that’s been collected over a considerable amount of time – think decades. Standard surveys don’t allow for this type of analysis. We can look at differences across age groups, but we can’t compare age groups over time.

Another complication is that the surveys we conducted 20 or 30 years ago aren’t usually comparable enough to the surveys we’re doing today. Our earlier surveys were done over the phone, and we’ve since transitioned to our nationally representative online survey panel , the American Trends Panel . Our internal testing showed that on many topics, respondents answer questions differently depending on the way they’re being interviewed. So we can’t use most of our surveys from the late 1980s and early 2000s to compare Gen Z with Millennials and Gen Xers at a similar stage of life.

This means that most generational analysis we do will use datasets that have employed similar methodologies over a long period of time, such as surveys from the U.S. Census Bureau. A good example is our 2020 report on Millennial families , which used census data going back to the late 1960s. The report showed that Millennials are marrying and forming families at a much different pace than the generations that came before them.

Even when we have historical data, we will attempt to control for other factors beyond age in making generational comparisons. If we accept that there are real differences across generations, we’re basically saying that people who were born around the same time share certain attitudes or beliefs – and that their views have been influenced by external forces that uniquely shaped them during their formative years. Those forces may have been social changes, economic circumstances, technological advances or political movements.

When we see that younger adults have different views than their older counterparts, it may be driven by their demographic traits rather than the fact that they belong to a particular generation.

The tricky part is isolating those forces from events or circumstances that have affected all age groups, not just one generation. These are often called “period effects.” An example of a period effect is the Watergate scandal, which drove down trust in government among all age groups. Differences in trust across age groups in the wake of Watergate shouldn’t be attributed to the outsize impact that event had on one age group or another, because the change occurred across the board.

Changing demographics also may play a role in patterns that might at first seem like generational differences. We know that the United States has become more racially and ethnically diverse in recent decades, and that race and ethnicity are linked with certain key social and political views. When we see that younger adults have different views than their older counterparts, it may be driven by their demographic traits rather than the fact that they belong to a particular generation.

Controlling for these factors can involve complicated statistical analysis that helps determine whether the differences we see across age groups are indeed due to generation or not. This additional step adds rigor to the process. Unfortunately, it’s often absent from current discussions about Gen Z, Millennials and other generations.

When we can’t do generational analysis, we still see value in looking at differences by age and will do so where it makes sense. Age is one of the most common predictors of differences in attitudes and behaviors. And even if age gaps aren’t rooted in generational differences, they can still be illuminating. They help us understand how people across the age spectrum are responding to key trends, technological breakthroughs and historical events.

Each stage of life comes with a unique set of experiences. Young adults are often at the leading edge of changing attitudes on emerging social trends. Take views on same-sex marriage , for example, or attitudes about gender identity .

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By choosing not to use the standard generational labels when they’re not appropriate, we can avoid reinforcing harmful stereotypes or oversimplifying people’s complex lived experiences.

Existing generational definitions also may be too broad and arbitrary to capture differences that exist among narrower cohorts. A typical generation spans 15 to 18 years. As many critics of generational research point out, there is great diversity of thought, experience and behavior within generations. The key is to pick a lens that’s most appropriate for the research question that’s being studied. If we’re looking at political views and how they’ve shifted over time, for example, we might group people together according to the first presidential election in which they were eligible to vote.

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New research from the group of MIT Professor Brett McGuire has revealed the presence of a previously unknown molecule in space. The team's open-access paper, “ Rotational Spectrum and First Interstellar Detection of 2-Methoxyethanol Using ALMA Observations of NGC 6334I ,” appears in April 12 issue of The Astrophysical Journal Letters .

Zachary T.P. Fried , a graduate student in the McGuire group and the lead author of the publication, worked to assemble a puzzle comprised of pieces collected from across the globe, extending beyond MIT to France, Florida, Virginia, and Copenhagen, to achieve this exciting discovery. 

“Our group tries to understand what molecules are present in regions of space where stars and solar systems will eventually take shape,” explains Fried. “This allows us to piece together how chemistry evolves alongside the process of star and planet formation. We do this by looking at the rotational spectra of molecules, the unique patterns of light they give off as they tumble end-over-end in space. These patterns are fingerprints (barcodes) for molecules. To detect new molecules in space, we first must have an idea of what molecule we want to look for, then we can record its spectrum in the lab here on Earth, and then finally we look for that spectrum in space using telescopes.”

Searching for molecules in space

The McGuire Group has recently begun to utilize machine learning to suggest good target molecules to search for. In 2023, one of these machine learning models suggested the researchers target a molecule known as 2-methoxyethanol. 

“There are a number of 'methoxy' molecules in space, like dimethyl ether, methoxymethanol, ethyl methyl ether, and methyl formate, but 2-methoxyethanol would be the largest and most complex ever seen,” says Fried. To detect this molecule using radiotelescope observations, the group first needed to measure and analyze its rotational spectrum on Earth. The researchers combined experiments from the University of Lille (Lille, France), the New College of Florida (Sarasota, Florida), and the McGuire lab at MIT to measure this spectrum over a broadband region of frequencies ranging from the microwave to sub-millimeter wave regimes (approximately 8 to 500 gigahertz). 

The data gleaned from these measurements permitted a search for the molecule using Atacama Large Millimeter/submillimeter Array (ALMA) observations toward two separate star-forming regions: NGC 6334I and IRAS 16293-2422B. Members of the McGuire group analyzed these telescope observations alongside researchers at the National Radio Astronomy Observatory (Charlottesville, Virginia) and the University of Copenhagen, Denmark. 

“Ultimately, we observed 25 rotational lines of 2-methoxyethanol that lined up with the molecular signal observed toward NGC 6334I (the barcode matched!), thus resulting in a secure detection of 2-methoxyethanol in this source,” says Fried. “This allowed us to then derive physical parameters of the molecule toward NGC 6334I, such as its abundance and excitation temperature. It also enabled an investigation of the possible chemical formation pathways from known interstellar precursors.”

Looking forward

Molecular discoveries like this one help the researchers to better understand the development of molecular complexity in space during the star formation process. 2-methoxyethanol, which contains 13 atoms, is quite large for interstellar standards — as of 2021, only six species larger than 13 atoms were detected outside the solar system , many by McGuire’s group, and all of them existing as ringed structures.  

“Continued observations of large molecules and subsequent derivations of their abundances allows us to advance our knowledge of how efficiently large molecules can form and by which specific reactions they may be produced,” says Fried. “Additionally, since we detected this molecule in NGC 6334I but not in IRAS 16293-2422B, we were presented with a unique opportunity to look into how the differing physical conditions of these two sources may be affecting the chemistry that can occur.”

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Borderline Personality Disorder

The latest theory on borderline personality disorder, new research uses logic to understand people with borderline disorder..

Posted April 27, 2024 | Reviewed by Lybi Ma

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  • A new approach uses statistical modeling to see what factors influence the tendency toward splitting.
  • People with this disorder can use their experiences to help overcome splitting and achieve integration.

When you think of someone with borderline personality disorder , it’s likely that you imagine their tendency to let their emotions veer out of control, become overly intrusive, and alternate between loving and hating the same individual, or what’s known as “splitting.”

Perhaps you have an in-law who you know has this diagnosis, and as much as you would like to show understanding and empathy, it’s difficult when they decide to make you the target of the hate side of the splitting equation. If only you could figure out what’s behind these stormy changes of heart, perhaps you could get along better, if not become a trusted source of help. New research uses a logical analysis to provide some clues.

The Logic of Splitting in Borderline Personality Disorder

According to the University of College London’s Giles Story and colleagues (2024), traditional theories of this disorder regard splitting as an offshoot of unhealthy early emotional development, in which “an infant structures its experience by discriminating between positive and negative affect… [leading to] disconnected states of extreme satisfaction and frustration.” (p. 750) In ordinary development, individuals learn to bring these two states into balance as the bonds with their caregivers become stable and enduring, regardless of whether their needs are satisfied or frustrated. In BPD, though, this integration fails to occur, and individuals come to acquire split representations not just of other people, but of themselves.

Tracing the development of these “object relations” approaches to BPD, Story and colleagues maintain that these approaches miss the mark by considering only emotional aspects of splitting and not potential cognitive ones. Instead, the UCL authors propose a framework of probabilistic inference. Perhaps people with BPD form the wrong conclusions when they try to establish the causes of other people’s behaviors.

Everyone engages in this type of speculation, whether BPD or not. Even a simple act such as someone smiling at you could have you wonder what’s behind their apparent good intentions. Did you do something they liked, which would be a “situational” cause, or are they just people who tend to smile (“dispositional” cause)? You might then go on to observe their future behavior which would allow you to settle the question.

There are many possible variants of the situational versus dispositional attributional process. If you like someone, you’ll be more inclined to view good behavior as dispositional. If someone generally behaves a certain way and then suddenly shows the opposite behavior, it must be situational. For the most part, these reasoning processes are rational, allowing individuals to test “hypotheses” about why others behave as they do. In BPD, all-or-nothing reasoning sets in, in which people tend to view the causes of other people’s behavior in overly simplistic, all-or-nothing ways.

A Statistical Modeling Approach to Splitting

In ordinary experience, Story and colleagues propose, people go through statistical thinking known as “Bayesian,” in which they change the probabilities of a person’s behavior reflecting dispositional factors based on behaviors as they unfold over time. The first time you see a stranger smile, you have no idea whether they are nice, or not. However, as you see them continuing to smile regardless of what’s happening around them, the odds increasingly shift in favor of a dispositional attribution. If people with BPD can’t make that calculation, they’ll judge someone’s personality based on a snap judgment that won’t change over time. Splitting, in this view, becomes “a distorted causal inference.” They don’t, as the authors propose, update a “person prior” (p. 757). Once nice, always nice, and vice versa. The “split priors,” in which people are all bad or all good become “impervious to learning." (p. 762)

The UCL authors ran statistical models on data from a prior study of participants with BPD and non-BPD controls given the simulated task of judging the moral character of “Person A” toward “Person B.” Ordinarily if you were making such a judgment with no “prior person,” you would have to wait to see what Person A actually did in a given situation and then update your judgments. By running a model against the actual data from participants as they judged whether Person A was a good or a bad “agent,” Story and colleagues could determine whether the groups differed in their ability to draw Bayesian inferences.

Not only did the findings confirm the predictions of differences in attributional processes between BPD and non-BPD groups, but the authors were also able to run a model to show how the tendency to engage in splitting could potentially be modified. Part of the problem in making attributions in general is that sometimes the external context in which people act isn’t all that clear-cut. The lack of clarity only feeds into the tendency of people with BPD to draw conclusions based on their initial impressions of others. However, by creating a model in which precise information is available about Person A’s behavior, attributions based on splitting diminish and a more integrated, and realistic, set of judgments can emerge.

Turning Statistical Modeling into Intervention

The job of intervention is to help “split priors” to be updated by data from experience, using the processes described through the Bayesian modeling. Consider the example provided by the authors. A person with BPD might jump to the conclusion that if someone they’re supposed to meet is late, this proves that “they hate me.” Intervention can help the individual take extra external information into account (such as heavy traffic). Training the individual to be more sensitive to situational factors would reduce the tendency to make judgments based not on what people do, but on how they imagine people to be (all good or all bad).

new topics for psychology research

In general, it is a good idea to let the evidence influence your judgments of people, but for individuals who tend to block out the data from experience, this type of intervention could help the person with BPD become more attuned to what the people around them are actually doing. Additionally, based on the Bayesian model, in which your judgments about probability should shift depending on prior outcomes, training people to monitor their conclusions about people over time would help individuals integrate positive and negative judgments rather than shift toward one or the other.

To sum up, whatever early experiences shape the individual with BPD are less important, in this approach, than the logic of the decisions the individual makes in the here and now. Giving people with this disorder the power and knowledge to observe themselves over time can help build the fulfillment that comes from an integrated view of the people in their lives.

Story, G. W., Smith, R., Moutoussis, M., Berwian, I. M., Nolte, T., Bilek, E., Siegel, J. Z., & Dolan, R. J. (2024). A social inference model of idealization and devaluation. Psychological Review , 131 (3), 749-780. https://doi.org/10.1037/rev0000430

Susan Krauss Whitbourne Ph.D.

Susan Krauss Whitbourne, Ph.D. , is a Professor Emerita of Psychological and Brain Sciences at the University of Massachusetts Amherst. Her latest book is The Search for Fulfillment.

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Automated machine learning robot unlocks new potential for genetics research

This technology will save labs time and money while enabling large-scale experiments.

University of Minnesota Twin Cities researchers have constructed a robot that uses machine learning to fully automate a complicated microinjection process used in genetic research.

In their experiments, the researchers were able to use this automated robot to manipulate the genetics of multicellular organisms, including fruit fly and zebrafish embryos. The technology will save labs time and money while enabling them to more easily conduct new, large-scale genetic experiments that were not possible previously using manual techniques

The research is featured on the cover of the April 2024 issue of GENETICS , a peer-reviewed, open access, scientific journal. The work was co-led by two University of Minnesota mechanical engineering graduate students Andrew Alegria and Amey Joshi. The team is also working to commercialize this technology to make it widely available through the University of Minnesota start-up company, Objective Biotechnology.

Microinjection is a method for introducing cells, genetic material, or other agents directly into embryos, cells, or tissues using a very fine pipette. The researchers have trained the robot to detect embryos that are one-hundredth the size of a grain of rice. After detection, the machine can calculate a path and automate the process of the injections.

"This new process is more robust and reproducible than manual injections," said Suhasa Kodandaramaiah, a University of Minnesota mechanical engineering associate professor and senior author of the study. "With this model, individual laboratories will be able to think of new experiments that you couldn't do without this type of technology."

Typically, this type of research requires highly skilled technicians to perform the microinjection, which many laboratories do not have. This new technology could expand the ability to perform large experiments in labs, while reducing time and costs.

"This is very exciting for the world of genetics. Writing and reading DNA have drastically improved in recent years, but having this technology will increase our ability to perform large-scale genetic experiments in a wide range of organisms," said Daryl Gohl, a co-author of the study, the group leader of the University of Minnesota Genomics Center's Innovation Lab and research assistant professor in the Department of Genetics, Cell Biology, and Development.

Not only can this technology be used in genetic experiments, but it can also help to preserve endangered species through cryopreservation, a preservation technique conducted at ultra-low temperatures.

"You can use this robot to inject nanoparticles into cells and tissues that helps in cryopreservation and in the process of rewarming afterwards," Kodandaramaiah explained.

Other team members highlighted other applications for the technology that could have even more impact.

"We hope that this technology could eventually be used for in vitro fertilization, where you could detect those eggs on the microscale level," said Andrew Alegria, co-lead author on the paper and University of Minnesota mechanical engineering graduate research assistant in the Biosensing and Biorobotics Lab.

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Story Source:

Materials provided by University of Minnesota . Note: Content may be edited for style and length.

Journal Reference :

  • Andrew D Alegria, Amey S Joshi, Jorge Blanco Mendana, Kanav Khosla, Kieran T Smith, Benjamin Auch, Margaret Donovan, John Bischof, Daryl M Gohl, Suhasa B Kodandaramaiah. High-throughput genetic manipulation of multicellular organisms using a machine-vision guided embryonic microinjection robot . GENETICS , 2024; 226 (4) DOI: 10.1093/genetics/iyae025

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