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The Ebola Wars: General Edition

By Tracie M. Addy, Linda M. Iadarola, Derek Dube

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The Ebola Wars: General Edition

This case study introduces students to viruses and is suitable for a general biology course. Terry is a college student who travels to a West African clinic for the summer as a volunteer. While abroad, Terry comes into contact with a patient infected with the Ebola virus and later displays the signs and symptoms of an Ebola virus infection. Over the course of the case study Terry learns about the general features of viruses, viral life cycles, in addition to the unique features of the Ebola virus and treatment options. The case is presented in an interrupted fashion. Students are expected to have prior knowledge of protein, lipid and nucleic acid structure and function, the parts of the cells (e.g., the properties of the cell membrane and the role of ribosomes) and the central dogma (e.g., the processes of transcription and translation). An advanced version of the case, intended for upper level undergraduate and graduate students, is also available on this site.

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  • Describe the different parts that make up the structure of a virus.
  • Explain the five steps needed for a virus to infect a host cell.
  • Describe how receptors on host cells are important for viral attachment to host cells.
  • Explain how a virus gains entry into the host cell.
  • Describe what parts of the host cell are used for virus replication and how a virus leaves when replication is complete.
  • Describe major structural features of the Ebola virus.
  • Label the major steps in the Ebola virus life cycle.
  • Describe the general options available for currently treating Ebola virus infections.

Viruses; Ebola virus; Ebola therapy; viral structure; infection; viral life cycle; disease; capsid; glycoproteins; immunotherapy; ZMapp

  

Subject Headings

EDUCATIONAL LEVEL

High school, Undergraduate lower division

TOPICAL AREAS

TYPE/METHODS

Teaching Notes & Answer Key

Teaching notes.

Case teaching notes are protected and access to them is limited to paid subscribed instructors. To become a paid subscriber, purchase a subscription here .

Teaching notes are intended to help teachers select and adopt a case. They typically include a summary of the case, teaching objectives, information about the intended audience, details about how the case may be taught, and a list of references and resources.

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Answer Keys are protected and access to them is limited to paid subscribed instructors. To become a paid subscriber, purchase a subscription here .

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Materials & Media

Supplemental materials.

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  • NEWS FEATURE
  • 11 September 2019

Exclusive: Behind the front lines of the Ebola wars

You can also search for this author in PubMed   Google Scholar

Health workers in a war-weary region are confronted with Ebola, a deadly virus that has claimed more than 2,000 lives. Credit: John Wessels for Nature

This story was supported by the Pulitzer Center on Crisis Reporting.

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Nature 573 , 178-183 (2019)

doi: https://doi.org/10.1038/d41586-019-02673-7

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IMAGES

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COMMENTS

  1. Ebola Case Study

    NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE ##### "The Ebola Wars: General Edition" by Addy, Iadarola, & Dube Page 2. V ir uses have either a DNA or RNA genome, which can be single- or double-str anded. T hese genomes are housed in a capsid made of proteins. Viruses can be classified by their specific genomes

  2. PDF The Ebola wars advanced edition

    Te additional viral particles produced inside host cells can exit and infect other cells. "Tese viruses seem kind of creepy," thought Terry. "Tey're like parasites to cells.". Terry continued reading: "Te Ebola Wars: Advanced Edition" by Dube, Iadarola, & Addy. Viruses have either a DNA or RNA genome, which can be single- or ...

  3. PDF The ebola wwars general edition

    NATIONAL CENTER FOR CASE STUDY TEACHING IN SCIENCE . Part IV - The Ebola Wars . In the middle of searching for more information on the Ebola virus, Terry began to feel gravely ill. Feverish, achy, nauseated and weak, Terry's worst fears came true—the symptoms were consistent with an Ebola virus infection.

  4. EBOLA WARS CASE STUDY Flashcards

    viruses are intracellular obligate parasites; they enter and hijack the host cell machinery to replicate; they are not able to replicate or metabolize without the host cell. because the abilities to reproduce and metabolize on their own is a major property of all living things, and viruses are unable to do so without the host cell, they are therefore classified as non-living

  5. The Ebola Wars: Mission Immune Evasion

    Abstract. Through a unique anthropomorphic view and the integration of game-based learning, this case study explores how the Ebola virus can evade the immune response. In working through the case, students are challenged to examine the first, second and third lines of defense of the immune response and the weapons that the Ebola virus employs ...

  6. PDF preparing for the ebola wars

    Te following information is intended to prepare you for the case study "The Ebola Wars: Mission Immune Evasion.". After reading this document, you should be able to: List the major Ebola genes involved in the evasion of the host cell immune response. Explain the role of the proteins encoded by Ebola genes in evading the immune response.

  7. The Ebola Wars: Advanced Edition

    Abstract. This case study was written for upper level undergraduate and graduate students to review foundational aspects of virology and to examine Ebola virus infection in detail. Terry is a college student who travels to a West African clinic for the summer as a volunteer. While abroad, Terry comes into contact with a patient infected with ...

  8. Case Study-The Ebola Wars 1 .docx

    13. The Ebola virus outbreak of 2014 caused devastation in West Africa with many lives lost. This case study is written from the perspective of the Ebola virus to enhance understanding of how this deadly virus can evade the immune response. When the immune system wins the Ebola virus loses, and vice- versa.

  9. The Ebola Wars: General Edition

    Abstract. This case study introduces students to viruses and is suitable for a general biology course. Terry is a college student who travels to a West African clinic for the summer as a volunteer. While abroad, Terry comes into contact with a patient infected with the Ebola virus and later displays the signs and symptoms of an Ebola virus ...

  10. Ebola Wars Answer Key-3.docx

    Name Case Study—The Ebola Wars Read through all the sections of this case study, and answer the questions as you progress through the case. Use this file to collect all your answers. Once you have finished, proofread your answers, and then submit this document to Canvas. Your submission will be run through VeriCite plagiarism software, so please make sure all your work is your own, written ...

  11. Exclusive: Behind the front lines of the Ebola wars

    This cornerstone of the Ebola response, called contact tracing, is the key to stopping the virus's transmission. In a country with a strong, centralized network of doctors and public-health ...

  12. Case Study- The Ebola Wars.docx

    View Case Study- The Ebola Wars.docx from BIO 522 at Alabama A&M University. 1 Case Study: The Ebola Wars Part I -What Is a Virus? ... Budding Key similarities and differences : Each have similar factors . However , Ebola is the only one that does budding . 6 o GP Trimer ... Explain your answer. Keep in mind the Ebola virus structures and that ...

  13. Enhancing Student Learning on Emerging Infectious Diseases: An Ebola

    Case Study Design Using a storyline with a main character and probable scenario of infection, The Ebola Wars: General Edition supports student learning of the general attributes of viruses, and application of their general knowledge of virology to the specific biological features of the Ebola virus. The case uses a stepwise approach to guide ...

  14. Solved BATIONAL CENTEREDE CASE STUDY TEACHING SCIENCE Part

    Biology questions and answers. BATIONAL CENTEREDE CASE STUDY TEACHING SCIENCE Part IV - The Ebola Wars In the middle of searching for more information on the Ebola virus, Terry began to feel gravely ill, Feverish, achy, nauseated and weak. Terry's worst fears came true the symptoms were consistent with an Ebola virus infection.

  15. CASE STUDY: EBOLA Flashcards

    Know how virsuses make new viruses. (A) The Ebola virus is enclosed in a package that contains RNA, its genetic "blueprint" for reproduction. (B) Ebola has a protein called glycoprotein that sticks out of its membrane and binds to receptors (in red) on the cell surface. (C) The binding of these receptors triggers a cell "eating" process called ...

  16. Ebola War Flashcards

    Study with Quizlet and memorize flashcards containing terms like What is the Ebola virus and where do they believe the virus lives?, How is the Ebola virus spread?, Is there a vaccine or cure for Ebola? and more. ... Ebola Case Study. 42 terms. Evangelina_Din. Preview. The Autobiography & Virginia Convention. Teacher 21 terms. afuggiti. Preview ...

  17. Complete the case study, The Ebola Wars First,

    Biology questions and answers. Complete the case study, The Ebola Wars First, download the case study. Second, work through the case, answering all question. Submit pictures of all viruses constructed and the completed case study to Moodle. Question: Complete the case study, The Ebola Wars First, download the case study.

  18. PDF The ebola wars

    The Ebola virus outbreak of 2014 caused devastation in West Africa with many lives lost. This case study is written from the perspective of the Ebola virus to enhance understanding of how this deadly virus can evade the immune response. When the immune system wins the Ebola virus loses, and vice-versa.

  19. Ebola Case Study Flashcards

    Ebola Case Study. Ebola Symptoms. Click the card to flip 👆. 1) Flu-like (headache, fever, muscle pain, sore throat. 2) Stomach pain. 3) Vomiting. 4) Diarrhea. 5) Bruising, hemorrhaging. *Can appear like malaris, dengue fever, Marburg virus disease, and other viral hemorrhagic devers.

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    What makes the the ebola wars general edition answer key legally binding? Because the world takes a step away from office working conditions, the completion of documents increasingly occurs electronically. The ebola wars answer key isn't an exception. Working with it using electronic means is different from doing so in the physical world.

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    Study with Quizlet and memorize flashcards containing terms like -working with the decontamination team @ the clinic -*unnoticed error, a microscopic puncture in her hazmat suit, or incorrectly removed her gloves or facemask*, 1) fever 2) rash 3) blood-shot eyes 4) body pain 5) deterioration 6) nausea 7) vomiting 8) diarrhea 9) internal bleeding, passive immunity and more.

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    Prepare a file. Use the Add New button. Then upload your file to the system from your device, importing it from internal mail, the cloud, or by adding its URL. 3. Edit ebola wars answer key form. Replace text, adding objects, rearranging pages, and more. Then select the Documents tab to combine, divide, lock or unlock the file.

  23. Microbiology-Case Studies(Ebola) Flashcards

    Microbiology-Case Studies (Ebola) Describe the highlights of the different stages of Ebola disease. Incubation: Symptoms may appear anywhere from 2 to 21 days after exposure to Ebola, but the average is 8 to 10 days. Prodromal: <1 week, Abrupt onset fever, severe prostration, headache, myalgias. Invasive: Elevated body temperature or subjective ...